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Factors influencing COVID-19 vaccination intention among university students:A cross-sectional study in Malaysia

Biosafety and Health 2023年第1期5卷 37-44页

作者： Chee Yin Wong Jen Sern Tham Chai Nien Foo Foong Leng Ng Saleha Shahar Mohd Nizam Zahary Mohd Nazri Ismail cheng siang tan Boon Peng Hoh Subbiah Vijay Kumar Yang Mooi Lim Center for Cancer Research Universiti Tunku Abdul RahmanKajang 43000Malaysia M.Kandiah Faculty of Medicine&Health Sciences Universiti Tunku Abdul RahmanKajang 43000Malaysia Department of Communication Faculty of Modern Languages and CommunicationUniversiti Putra MalaysiaSerdang 43400Malaysia UPM-UNICEF C4D Faculty of Modern Languages and CommunicationUniversiti Putra MalaysiaSerdang 43400Malaysia Faculty of Science Universiti Teknologi MalaysiaJohor Bahru 81310Malaysia Faculty of Health Sciences Universiti Sultan Zainal AbidinKuala Nerus 21300Malaysia Analytical Biochemistry Research Centre Universiti Sains MalaysiaBayan Lepas 11900Malaysia Faculty of Medicine and Health Sciences Universiti Malaysia SarawakKota Samarahan 94300Malaysia Faculty of Medicine and Health Sciences UCSI UniversityCheras 56000Malaysia Biotechnology Research Institute Universiti Malaysia SabahKota Kinabalu 88400Malaysia

Vaccination is crucial in controlling the spread of the coronavirus disease 2019(COVID-19)that triggered the pandemic,but herd immunity can only work with high vaccination coverage in the *** study aims to measure the COVID-19 knowledge level and determine the factors influencing COVID-19 vaccination intention among university students in Malaysia.A cross-sectional online survey was carried out with 1,274 Malaysian university students in July *** and multivariate analyses were employed to examine the relationships between the study *** showed that the majority of university students had an acceptable level of knowledge of *** knowledge,risk perception of COVID-19,social norms,and perceived benefit of COVID-19 vaccination were positively associated with vaccination ***,perceived trust in information sources of COVID-19 vaccination and the government's response to COVID-19 did not affect the university students’desire to receive the *** findings are essential for health policymakers and healthcare providers to implement evidence-based interventions to increase COVID-19 vaccination uptake among university students.

关键词： Behavioral intention COVID-19 Influencing factor SARS-CoV-2 University student Vaccination

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Pyogenic liver abscess caused by Klebsiella pneumoniae:analysis of the clinical characteristics and outcomes of 84 patients

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Chinese Medical Journal 2007年第2期120卷 136-139页

作者： CHAN Khee-siang YU Wen-liang TSAI Chi-lun cheng Kuo-chen HOU Ching-cheng LEE Meng-chih tan Che-kim Department of Intensive Care Medicine Chi Mei Medical Center Tainan Taiwan 710 China Institute of Medicine Chung Shan Medical University Taichung Taiwan 400 China

Background The increased incidence of pyogenic liver abscess caused by Klebsiella pneumoniae （***） was reported in the recent literature. This study was conducted retrospectively to investigate the clinical characteristics and outcomes of these patients. Methods Microbiological and medical databases of a medical center were searched from January 2000 to June 2003. Eighty-four patients with liver abscess caused by K. pneumoniae were analyzed. Results In the 84 patients, 52 men and 32 women aged （58.2±13.3） years on average, 64.4% had concomitant diabetes mellitus and 23.8% had biliary disease. The most common clinical symptoms were fever （98.8%）, chills （69.0%） and abdominal pain （58.3%）. 85.7% of the 84 patients received catheter drainage for the abscess. The length of hospital stay was （17.4 ±8.7） days. The mortality rate was 7.1%. Older age and presence of biliary disease were associated with mortality. Conclusions The low mortality of our patients was probably related to the high proportion of patients who received catheter drainage. Older age and presence of biliary disease were associated with the mortality.

关键词： Klebsiella pneumoniae liver abscess biliary tract disease

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Utilization of Infused Tea Leaves (Camellia sinensis) for the Removal of Pb²⁺, Fe²⁺ and Cd²⁺ Ions from Aqueous Solution: Equilibrium and Kinetic Studies

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Journal of Water Resource and Protection 2016年第5期8卷 568-582页

作者： Chen Son Yue Kok How Chong Cheah cheng Eng Ling siang Loh Faculty of Applied Sciences and Computing Tunku Abdul Rahman University College Kuala Lumpur Malaysia

In this study, infused tea leaves as a low-cost adsorbent have been used in the removal of the Pb2+, Fe2+ and Cd2+ ions from aqueous solution. The adsorption study was carried out in a batch process and the effects of parameters such as initial pH, adsorbent dose, contact time and initial metal ion concentration were investigated. Experimental results showed that the maximum adsorption of metal ions occurred at pH 5 for Pb2+ and Fe2+ and at pH 6 for Cd2+. Adsorption of metal ions increased with increasing adsorbent concentration and contact time. The isothermal data for the adsorption of metal ions by infused tea leaves were found to fit well with the Langmuir equations. Based on the experimental data of the Langmuir isotherm model, the maximum adsorption capacities of the metal ions onto the infused tea leaves were found in the order of Pb2+ > Cd2+ > Fe2+ with the adsorption capacities of 26.32 mg·gǃ, 14.29 mg·gǃ and 12.38 mg·gǃ respectively. The adsorption process followed the pseudo-second order reaction and the corresponding rate constant were found to be 4.30 × 10ǅ g·mgǃ·minǃ, 1.75 × 10ǃ g·mgǃ·minǃ and 1.45 × 10Ǆ g·mgǃ·minǃ for Pb2+, Fe2+ and Cd2+ ions respectively.

关键词： Infused Tea Leaves Isotherms Kinetics Lead Cadmium Iron

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Differential subcellular distribution renders HAI-2 a less effective protease inhibitor than HAI-1 in the control of extracellular matriptase proteolytic activity

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Genes & Diseases 2022年第4期9卷 1049-1061页

作者： Yi-Lin Chiu Yi-Ying Wu Robert B.Barndt Yu-Wen Lin Hou-Ping Sytwo Amy cheng Kacy Yang Khee-siang Chan Jehng-Kang Wang Michael D.Johnson Chen-Yong Lin Lombardi Comprehensive Cancer Center Department of Oncology Georgetown UniversityWashingtonDC 20057USA Department of Biochemistry National Defense Medical CenterTapei 114Chinese Taipei Division of Hematology/Oncology Department of Internal MedicineTri-Service General HospitalNational Defense Medical CenterTapei 114Chinese Taipei School of Medicine National Defense Medical CenterTapei 114Chinese Taipei Department of Intensive Care Medicine Chi Mei Medical CenterTainan 710Chinese Taipei

The integral membrane,Kunitz-type serine protease inhibitors HAI-1 and HAI-2,can suppress the proteolytic activity of the type 2 transmembrane serine protease matriptase with high specificity and *** levels of extracellular matriptase proteolytic activity have,however,been observed in some neoplastic B-cells with high levels of endogenous HAI-2,indicating that HAI-2 may be an ineffective matriptase inhibitor at the cellular *** different effectiveness of the HAIs in the control of extracellular matriptase proteolytic activity is examined *** inducing matriptase zymogen activation in the HAI Teton Daudi Burkitt lymphoma cells,which naturally express matriptase with very low levels of HAI-2 and no HAI-1,nascent active matriptase was rapidly inhibited or shed as an enzymatically active *** increasing HAI-1 expression,cellular matriptase-HAI-1 complex increased,and extracellular active matriptase decreased *** HAI-2 expression,however,resulted in cellular matriptase-HAI-2 complex levels reaching a plateau,while extracellular active matriptase remained *** contrast to this differential effect,both HAI-1 and HAI-2,even at very low levels,were shown to promote the expression and cell-surface translocation of endogenous *** difference in the suppression of extracellular active matriptase by the two closely related serine protease inhibitors could result from the primarily cell surface expression of HAI-1 compared to the mainly intracellular localization of *** HAIs,therefore,resemble one another with respect to promoting matriptase expression and surface translocation but differ in their effectiveness in the control of extracellular matriptase enzymatic activity.

关键词： HAI-1 HAI-2 Matriptase Neoplastic B-cells Proteolytic activity

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Power Generation Characteristics of Piezoelectric Ceramics Bimorph Structure

Power Generation Characteristics of Piezoelectric Ceramics B...

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2011年全国压电和声波理论及器件应用研讨会

作者： Ming-cheng Chure King-Kung Wu siang-Bin Fang Department of Electronics Engineering Far-East University49 Chung-Hua RoadSinshih DistrictTainan CityTaiwanROC.

＜正＞Open circuit voltage of the bimorph structure increased with the increasing of the impact *** circuit voltage of the series structure is higher than that of parallel *** current also increased with the increasing of the impact force,but it decreased with the increasing of load *** power output is increased with the increasing of load *** structure with fiberglass reinforced plastic（FPR） base had higher open circuit voltage then that with metal base.

关键词： piezoelectric ceramics bimorph structure power generation characteristics

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Superior Fidelity and Distinct Editing Outcomes of SaCas9 Compared with SpCas9 in Genome Editing

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Genomics, Proteomics & Bioinformatics 2023年第6期21卷 1206-1220页

作者： Zhi-Xue Yang Ya-Wen Fu Juan-Juan Zhao Feng Zhang Si-Ang Li Mei Zhao Wei Wen Lei Zhang Tao cheng Jian-Ping Zhang Xiao-Bing Zhang State Key Laboratory of Experimental Hematology National Clinical Research Center for Blood DiseasesHaihe Laboratory of Cell EcosystemInstitute of Hematology&Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China Center for Stem Cell Medicine Chinese Academy of Medical SciencesTianjin 300020China Department of Stem Cell&Regenerative Medicine Peking Union Medical CollegeTianjin 300020China

A series of clustered regularly interspaced short palindromic repeats(CRISPR)-CRISPR associated protein 9(Cas9)systems have been engineered for genome *** most widely used Cas9 is SpCas9 from Streptococcus pyogenes and SaCas9 from Staphylococcus ***,a comparison of their detailed gene editing outcomes is still *** characterizing the editing outcomes of 11 sites in human induced pluripotent stem cells(iPSCs)and K562 cells,we found that SaCas9 could edit the genome with greater efficiencies than *** also compared the effects of spacer lengths of single-guide RNAs(sgRNAs;18–21 nt for SpCas9 and 19–23 nt for SaCas9)and found that the optimal spacer lengths were 20 nt and 21 nt for SpCas9 and SaCas9,***,the optimal spacer length for a particular sgRNA was 18–21 nt for SpCas9 and 21–22 nt for ***,SpCas9 exhibited a more substantial bias than SaCas9 for nonhomologous end-joining(NHEJ)+1 insertion at the fourth nucleotide upstream of the protospacer adjacent motif(PAM),indicating a characteristic of a staggered ***,editing with SaCas9 led to higher efficiencies of NHEJ-mediated double-stranded oligodeoxynucleotide(dsODN)insertion or homology-directed repair(HDR)-mediated adeno-associated virus serotype 6(AAV6)donor ***,GUIDE-seq analysis revealed that SaCas9 exhibited significantly reduced off-target effects compared with *** work indicates the superior performance of SaCas9 to SpCas9 in transgene integration-based therapeutic gene editing and the necessity to identify the optimal spacer length to achieve desired editing results.

关键词： SpCas9 SaCas9 Spacer length Indel pattern Knock-in efficiency Off-target

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美国职工持股计划的实践与启示

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淮南职业技术学院学报 2001年第1期1卷 48-50页

作者：严成根项贤勇淮南矿业集团安徽淮南232001

职工持股计划(EMPLOYEE STOCK OWNERSHIP PLANS简称BSOP)是一种新型的产权激励制度,介绍了美国标准ESOP的制度设计,分析了ESOP在美国的实践和绩效情况,并在此基础上提出了美国ESOP对我国的借鉴意义。

关键词：美国职工持股计划实践产权激励制度制度设计借鉴意义企业制度绩效分析

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锡青铜中微量铁和锑的粉末法光谱分析

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吉林大学自然科学学报 1965年第3期 85-89页

作者：汪永祥刘再生郑衍生吉林大学吉林大学 1965年畢业生

本文提出了一种简便的粉末法光谱测定锡青铜中微量铁和锑的分析方法.同时对合金的主要组份Sn和Zn的含量变化的影响进行了研究.当Sn和Zn的含量分别在0-18％和0-8％范围内变化,对Fe和Sb的分析线对强度比无影响.应用本方法对三个10-2牌号... 详细信息

本文提出了一种简便的粉末法光谱测定锡青铜中微量铁和锑的分析方法.同时对合金的主要组份Sn和Zn的含量变化的影响进行了研究.当Sn和Zn的含量分别在0-18％和0-8％范围内变化,对Fe和Sb的分析线对强度比无影响.应用本方法对三个10-2牌号锡青铜样品进行了九次分析.结果表明,方法的再现性以标准偏差表示分别为Fe±5％和Sb±10％.加入试验证明,方法的准确度亦是令人满意的.

关键词：锡青铜牌号微量铁粉末法

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广东南雄晚白垩纪—早第三纪地层剖面的观察

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古脊椎动物与古人类 1973年第1期 18-30页

作者：郑家坚张英俊邱占祥叶祥奎中国科学院古脊椎动物与古人类研究所

自垩纪—三纪的“红色岩系”在华南广大地区相当发育。解放后,于湖南、江西、广东等地的红色地层中,先后发现了一些重要的脊椎动物及其他门类的化石。近年来,中国科学院古脊椎动物与古人类研究所在广东南雄进行了地层研究和化石发掘工作... 详细信息

自垩纪—三纪的“红色岩系”在华南广大地区相当发育。解放后,于湖南、江西、广东等地的红色地层中,先后发现了一些重要的脊椎动物及其他门类的化石。近年来,中国科学院古脊椎动物与古人类研究所在广东南雄进行了地层研究和化石发掘工作。1962—1963年,张玉萍、童永生等在该区“红色岩系”的不同层位中发现了一些化石,并作了分层,1963—1964年本文作者等,再次前往南雄调查,着重测制标准地点的剖面,并系统采集不同层位的化石。(图1)我们就这次观察所获,撰成本文,作为1962—1963年工作的补充记述,以便于今后对华南(尤其是南岭两

关键词：早第三纪砂质泥岩广东南雄砾石成分老第三纪泥质砂岩砂砾岩地层剖面南雄盆地

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4,4′二乙氧基二苯硫脲抗结核作用的实验疗效

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上海第一医学院学报 1964年第1期 101-105页

作者：崔祥瑸袁承炽张月娥杨藻宸上海第一医学院附属中山医院肺病学教研组上海第一医学院病理解剖学教研组上海第一医学院药理学教研组

4,4′二乙氧基二苯硫脲（简称双代硫脲）为白色结晶,分子结构（CH3CH2O（?）NH-CS-NH（?）OCH2CH3）,1953年经Mayer 氏等编号为 Su 1380,并认为在试管和动物实验中,都有一定的抗结核作用。于此期间,苏联亦有类似的报告,并命名为（安痨息... 详细信息

4,4′二乙氧基二苯硫脲（简称双代硫脲）为白色结晶,分子结构（CH3CH2O（?）NH-CS-NH（?）OCH2CH3）,1953年经Mayer 氏等编号为 Su 1380,并认为在试管和动物实验中,都有一定的抗结核作用。于此期间,苏联亦有类似的报告,并命名为（安痨息）,还在临床上证明了它的实用价值。为鉴定疗效起见,对双代硫脲进行了实验研究,本文报导这一研究的结果。实验方法和结果一、试管内制菌作用:双代硫脲不溶于水,

关键词：动物疗效小剂量豚鼠荷兰猪鼠蹊部疗程乙氧基烷氧基

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