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Arbitrary acoustic orbital angular momentum detection using dual-layer metasurfaces

Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 106-112页

作者： Zhanlei Hao Haojie Chen Yuhang Yin Shan Zhu Yadong Xu cheng-Wei qiu Huanyang Chen Department of Physics College of Physical Science and TechnologyXiamen UniversityXiamen 361005China Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Department of Mechanical and Electrical Engineering Xiamen UniversityXiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China School of Physical Science and Technology and Jiangsu Key Laboratory of Thin Films Soochow UniversitySuzhou 215006China

Orbital angular momentum(OAM),with its unique physical properties and vast application prospects,has attracted widespread attention in various fields.Nonetheless,the development of valid and practical acoustic OAM detection methods continues to be a challenging endeavor.In this paper,we propose a novel construction method of dual-layer metasurfaces to achieve a doubleconversion process for the waveform reshaping and differentiated focusing of two-dimensional vortex sources with different OAMs.Specifically,by utilizing a concise formula,a one-to-one correspondence is established between the OAM of incident vortex waves and different imaging points.The fundamental principle of this special conversion relationship is rigorously constrained by the directional compensation of phase and the material parameters of dual-layer metasurfaces with different quadratic phase distributions.More importantly,the highly consistent results between numerical demonstrations and acoustic experiments further confirm the feasibility and effectiveness of the proposed OAM detection scheme.Our work provides a new perspective on the precise manipulation for the phase of vortex fields,holding potential applications in super-resolution imaging and the design of acoustic OAM-based devices.

关键词： arbitrary acoustic OAM detection vortex waves dual-layer metasurfaces waveform reshaping differentiated focusing acoustic experiments

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Tunable VO_(2) cavity enables multispectral manipulation from visible to microwave frequencies

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Light(Science & Applications) 2024年第3期13卷 510-518页

作者： Hang Wei Jinxin Gu Tao Zhao Zhiyuan Yan He-Xiu Xu Shuliang Dou cheng-Wei qiu Yao Li Center for Composite Materials and Structure Harbin Institute of TechnologyHarbin 150001China National University of Singapore Department of Electrical&Computer EngineeringSingapore 117583Singapore School of Chemical Engineering and Technology Harbin Institute of TechnologyHarbin 150001China Suzhou Laboratory Suzhou 215123China

Optical materials capable of dynamically manipulating electromagnetic waves are an emerging field in memories,optical modulators,and thermal management.Recently,their multispectral design preliminarily attracts much attention,aiming to enhance their efficiency and integration of functionalities.However,the multispectral manipulation based on these materials is challenging due to their ubiquitous wavelength dependence restricting their capacity to narrow wavelengths.In this article,we cascade multiple tunable optical cavities with selective-transparent layers,enabling a universal approach to overcoming wavelength dependence and establishing a multispectral platform with highly integrated functions.Based on it,we demonstrate the multispectral(ranging from 400 nm to 3 cm),fast response speed(0.9 s),and reversible manipulation based on a typical phase change material,vanadium dioxide.Our platform involves tandem VO_(2)-based Fabry–Pérot(F-P)cavities enabling the customization of optical responses at target bands independently.It can achieve broadband color-changing capacity in the visible region(a shift of~60 nm in resonant wavelength)and is capable of freely switching between three typical optical models(transmittance,reflectance,and absorptance)in the infrared to microwave regions with drastic amplitude tunability exceeding 0.7.This work represents a state-of-art advance in multispectral optics and material science,providing a critical approach for expanding the multispectral manipulation ability of optical systems.

关键词： spectral microwave visible

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MicroRNA-409-5p Inhibits GIST Tumorigenesis and Improves Imatinib Resistance by Targeting KDM4D Expression

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Current Medical Science 2023年第5期43卷 935-946页

作者： cheng qiu Yong-dong FENG Xi YANG GI Cancer Research Institute Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Objective Gastrointestinal stromal tumors(GISTs)can rapidly proliferate through angiogenesis.Previous studies indicated the potential influence of microRNA on the progression of tumor immature angiogenesis.This study aimed to explore the specific mechanism by which microRNA-409-5p(miR-409-5p)contributes to GIST.Methods To identify genes potentially involved in the development and progression of GIST,the differences of miR-409-5p between tumors and adjacent tissues were first analyzed.Following this analysis,target genes were predicted.To further investigate the function of miRNA in GIST cells,two GIST cell lines(GIST-T1 and GIST882)were transfected with lentiviruses that stably expressed miR-409-5p and scrambled miRNA(negative control).Later,the cells were subjected to Western blotting and ELSA to determine any differences in angiogenesis-related genes.Results In GISTs,there was a decrease in the expression levels of miR-409-5p compared to the adjacent tissues.It was observed that the upregulation of miR-409-5p in GIST cell lines effectively inhibited the proteins hypoxia-inducible transcription factor 1β(HIF1β)and vascular endothelial growth factor A(VEGF-A).Further investigations revealed that miR-409-5p acted as an inhibitor of angiogenesis by binding to the 3′-UTR of Lysine-specific demethylase 4D(KDM4D)mRNA.Moreover,the combination of miR-409-5p with imatinib enhanced its inhibitory effect on angiogenesis.Conclusion This study demonstrated that the miRNA-409-5p/KDM4D/HIF1β/VEGF-A signaling pathway could serve as a novel target for the development of therapeutic strategies for the treatment of imatinib-resistance in GIST patients.

关键词： microRNA-409-5p KDM4D gastrointestinal stromal tumor

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Treatment strategy on traumatic mid-lumbar spondyloptosis with concomitant multiple injuries:A case report and literature review

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Chinese Journal of Traumatology 2023年第1期26卷 33-40页

作者： Lin cheng cheng qiu Xin-Yu Liu Xi-Guang Sang Department of Emergency Medicine Qilu Hospital of Shandong UniversityJinan250012China Department of Orthopaedic Surgery Qilu Hospital of Shandong UniversityJinan250012China Cheeloo College of Medicine Shandong UniversityJinan250012China

Spondyloptosis in the clinic is rarely reported.We herein present a 47-year-old female,who suffered from a crush injury directly by a heavy cylindrical object from the lateral side.She was diagnosed to have traumatic L3 spondyloptosis with multiple traumas.Staged surgical procedures were conducted and a three-year follow-up was obtained.Eventually,normal spinal alignment was restored,and neurological deficits were gradually improved.At three years follow-up,the motor strength scores and function of the sphincters were incompletely improved.Previously published reports on traumatic lumbar spondyloptosis were reviewed and several critical points for management of this severe type of spinal injury were proposed.First,thoracolumbar and lumbosacral junction were mostly predilection sites.Second,numerous patients involving traumatic lumbar spondyloptosis were achieved to American Spinal Injury Association grade A.Third,lumbar spondyloptosis was commonly coupling withcauda equina injury.Finally,the outcomes were still with poorly prognosis and recovery of patients was correlation to spondyloptosis severity.Based on this case report and literatures review,we highlighted that the spinal alignment restoration relying on staged operations and following rehabilitation hereof are both important once facing with multiple traumas.Furthermore,we suggested to perform routine CT angiography during lumbar spondyloptosis to justify whether there are large vessel compression or injury.

关键词： Spondyloptosis Multiple trauma Fracture dislocation American Spinal Injury Association Lumbar spine

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Exploring a novel class tryptophan hydroxylase 1 inhibitor derived from Sambucus williamsii Hance for the osteoporosis treatment

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Acupuncture and Herbal Medicine 2024年第1期4卷 102-112页

作者： Yu-Xin Zhu Zi-Ling Tang Lu Lu Zuo-cheng qiu Dabo Pan Yang Yu Hui-Hui Xiao Man-Sau Wong State Key Laboratory of Chinese Medicine and Molecular Pharmacology(Incubation) The Hong Kong Polytechnic University Shenzhen Research InstituteShenzhenChina Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine School of Traditional Chinese MedicineJinan UniversityGuangzhouChina Guangdong Provincial Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research College of PharmacyJinan UniversityGuangzhouChina Department of Food Science and Nutrition The Hong Kong Polytechnic UniversityHong KongChina Research Center for Chinese Medicine Innovation The Hong Kong Polytechnic UniversityHong KongChina

Objective:Gut-derived serotonin strongly inhibits bone formation by inhibiting osteoblast proliferation.Our previous study demonstrated that the lignan-rich fraction prepared from Sambucus willimasii Hance,a folk herbal medicine used to treat bone fractures and joint diseases in China,exerted bone-protective effects,and its actions were modulated by suppressing the synthesis of gut-derived serotonin via the inhibition of intestinal tryptophan hydroxylase 1(TPH-1).However,there is no direct evidence for the action of lignans on TPH-1.This study aimed to verify the direct action of lignans on the TPH-1 and its influence on serotonin synthesis and bone properties.Methods:Molecular docking and surface plasmon resonance were performed to determine the affinities of lignans to TPH-1.The cell viability and the protein activity and expression of TPH-1 were measured in RBL2H3 cells.The serum serotonin level and bone mineral density upon lignan treatment in ovariectomized mice were determined.Result:The lignans showed high binding scores and binding affinities to TPH-1,inhibited the activity and protein expression of TPH-1,suppressed the serum serotonin levels in ovariectomized mice as well as promoted bone mineral density.Conclusion:This is the first study to report that lignans are novel TPH-1 inhibitors and that these lignans could be potential agents for the management of serotonin-related diseases,including osteoporosis.

关键词： Lignan Osteoporosis Sambucus williamsii Hance Serotonin TPH-1 inhibitor

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Wearable and interactive multicolored photochromic fiber display

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Light(Science & Applications) 2024年第3期13卷 454-465页

作者： Pan Li Yuwei Wang Xiaoxian He Yuyang Cui Jingyu Ouyang Ju Ouyang Zicheng He Jiayu Hu Xiaojuan Liu Hang Wei Yu Wang Xiaoling Lu Qian Ji Xinyuan Cai Li Liu Chong Hou Ning Zhou Shaowu Pan Xiangru Wang Huamin Zhou cheng-Wei qiu Yan-Qing Lu Guangming Tao State Key Laboratory of Material Processing and Die&Mould Technology School of Materials Science and Engineering and Wuhan National Laboratory for OptoelectronicsHuazhong University of Science and TechnologyWuhan 430074China Key Laboratory of Vascular Aging(HUST) Ministry of EducationWuhan 430030China School of Optoelectronic Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore National Laboratory of Solid State Microstructures Key Laboratory of Intelligent Optical Sensing and ManipulationCollege of Engineering and Applied Sciencesand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210023China School of Performing Arts Wuhan Conservatory of MusicWuhan 430060China School of Mechanical Science and Engineering Huazhong University of Science and TechnologyWuhan 430074China School of Architecture and Urban Planning Huazhong University of Science and TechnologyWuhan 430074China School of Fashion Beijing Institute of Fashion TechnologyBeijing 100029China School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China Tongji Medical College Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai 201620China

Endowing flexible and adaptable fiber devices with light-emitting capabilities has the potential to revolutionize the current design philosophy of intelligent,wearable interactive devices.However,significant challenges remain in developing fiber devices when it comes to achieving uniform and customizable light effects while utilizing lightweight hardware.Here,we introduce a mass-produced,wearable,and interactive photochromic fiber that provides uniform multicolored light control.We designed independent waveguides inside the fiber to maintain total internal reflection of light as it traverses the fiber.The impact of excessive light leakage on the overall illuminance can be reduced by utilizing the saturable absorption effect of fluorescent materials to ensure light emission uniformity along the transmission direction.In addition,we coupled various fluorescent composite materials inside the fiber to achieve artificially controllable spectral radiation of multiple color systems in a single fiber.We prepared fibers on mass-produced kilometer-long using the thermal drawing method.The fibers can be directly integrated into daily wearable devices or clothing in various patterns and combined with other signal input components to control and display patterns as needed.This work provides a new perspective and inspiration to the existing field of fiber display interaction,paving the way for future human–machine integration.

关键词： fiber interactive colored

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Vortex localization and OAM selective conversion via cylindrical metagratings

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Chinese Optics Letters 2024年第3期22卷 137-141页

作者：郝占磊朱杉仇成伟徐亚东陈焕阳 Institute of Electromagnetics and Acoustics and Department of Physics College of Physical Science and TechnologyXiamen UniversityXiamen 361005China Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore School of Physical Science and Technology and Jiangsu Key Laboratory of Thin Films Soochow UniversitySuzhou 215006China

Vortex waves with orbital angular momentum(OAM)are a highly active research topic in various fields.In this paper,we design and investigate cylindrical metagratings(CMs)with an even number of unit cells that can efficiently achieve vortex localization and specific OAM selective conversion.The multifunctional manipulation of vortex waves and the new OAM conservation law have further been confirmed through analytical calculations and numerical simulations.In addition,we qualitatively and quantitatively determine the OAM range for vortex localization and the OAM value of vortex selective conversion and also explore the stability for performance and potential applications of the designed structure.This work holds potential applications in particle manipulation and optical communication.

关键词： vortex waves cylindrical metagratings vortex localization high-efficiency transmission vortex selective conversion

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Graphite recycling from spent lithium-ion batteries for fabrication of high-performance aluminum-ion batteries

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Rare Metals 2024年第5期43卷 2161-2171页

作者： Li Wang Chao Wang Jing-Yi Zhang Jia-cheng qiu Xu-Wang Fu Zi-Rui Zhang Jian-Min Feng Lei Dong Cong-Lai Long De-Jun Li Xiao-Wei Wang Bao Zhang Jia-Feng Zhang Rui-Rui Zhao College of Physics and Materials Science Tianjin Normal University National Engineering Laboratory for High Efficiency Recovery of Refractory Nonferrous Metals School of Metallurgy and Environment Central South University School of Chemistry South China Normal University

Efficient extraction of electrode components from recycled lithium-ion batteries （LIBs） and their highvalue applications are critical for the sustainable and ecofriendly utilization of resources.This work demonstrates a novel approach to stripping graphite anodes embedded with Li+from spent LIBs directly in anhydrous ethanol which can be utilized as high efficiency cathodes for aluminum-ion batteries （AIBs）.Recycled graphite （RG） with foam morphology and crystal structure defects was obtained under the action of ultrasonic peeling and gas generation reaction between residual lithium-graphite interlayer compound and ethanol.The inherent open structure of RG facilitates the intercalation/deintercalation of chloralum anions （AlCl4-） and enhances its AIB cathode performance.The electrochemical measurements revea that the RG cathode has a specific capacity of 123 m Ah·g-1at a current of 5 A·g-1,which is 1.55 times higher than tha of unprocessed natural graphite and 1.25 times higher than that of commercial artificial graphite.Additionally,the RG cathode demonstrated remarkable stability,retaining its high particular capacity of 138.15 mAh·g-1even through2000 times at 10 A·g-1in a low-cost electrolyte consisting of an ionic liquid/urea/AlCl3mixture.This work offers a novel approach to reusing of graphite anode waste materials from LIBs.

关键词： Aluminum ion batteries Lithium-ion batteries Graphite anode Recycling

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Inaugurating a novel adjuvant therapy in urological cancers:Ferroptosis

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Cancer Pathogenesis and Therapy 2023年第2期1卷 127-140页

作者： Zhaoxiang Xie Qianghua Zhou cheng qiu Dingjun Zhu Kaiwen Li Hai Huang Department of Urology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhouGuangdong 510120China Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation Sun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhouGuangdong 510120China Department of Orthopedic Surgery Qilu HospitalCheeloo College of MedicineShandong UniversityJinanShandong 250012China Department of Urology The Sixth Affiliated Hospital of Guangzhou Medical UniversityQingyuan People's HospitalQingyuanGuangdong 511518China

Ferroptosis,a distinctive form of programmed cell death,is involved in numerous diseases with specific characteristics,including certain cell morphology,functions,biochemistry,and genetics,that differ from other forms of programmed cell death,such as apoptosis.Many studies have explored ferroptosis and its associated mechanisms,drugs,and clinical applications in diseases such as kidney injury,stroke,ischemia-reperfusion injury,and prostate cancer.In this review,we summarize the regulatory mechanisms of some ferroptosis inducers,such as enzalutamide and erastin.These are current research focuses and have already been studied extensively.In summary,this review focuses on the use of ferroptosis induction as a therapeutic strategy for treating tumors of the urinary system.

关键词： Ferroptosis Urinary system Prostatic cancer Lipid ROS GPX4

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Water Flow Characteristics and Related Effects in PEMFC

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Fluid Dynamics & Materials Processing 2019年第4期15卷 431-444页

作者： Mingge Wu Lei Wang Yixiang Wang cheng Zhang cheng qiu College of mechanical and electrical engineering Wenzhou UniversityWenzhou325035China Haitian Drive Systems Co. Ltd.Ningbo315800China

Water management in proton exchange membrane fuel cells(PEMFC)is a topic of great importance for the optimization of these systems.Effective proton conductivity calls for moderate moisture content in the membrane,while uneven water distribution can lead to instability of the whole flow field,thereby decreasing the performance of the fuel cell.In the present study,a simplified two-tier hybrid structure is used to investigate the impact of the dynamic behavior of liquid water on the current density of the PEMFC.Simulation results show that water droplets attached to wall sides tend to increase current density.Visualization experiments confirm the existence of liquid droplets and the enhancement of current density,while indicating that the best performance and stability of fuel cell are attained for a cathode air flow rate of 300 ml/min.

关键词： PEMFC water management simulation airflow rate visualization

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