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Multislice spiral computed tomography imaging in evaluating hemophilic arthropathy

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Chinese Medical Journal 2020年第14期133卷 1669-1675页

作者： Yu-Xia Zhang M ei-Xia Li Shu-Fang Wei Lu Zhang tian-ming cheng Ying-Hui Ge Department of Medical Imaging People's Hospital of Zhengzhou UniversityHenan Provincial People's HospitalCentral China Fuwai HospitalZhengzhouHenan 450003China Department of Radiology The First Affiliated Hospital of Xinxiang Medical UniversityWeihuiHenan 453100China Department of Medical Imaging People's Hospital of Zhengzhou UniversityHenan Provincial People's HospitalZhengzhouHenan 450003China

Background:Certain hemophilia patients are unable to cooperate with or afford magnetic resonance imaging(MRI)*** purpose of our study was to explore the value of multislice spiral computed tomography(MSCT)in evaluating hemophilic arthropathy(HA).Methods:Thirty-eight patients with 73 joints of HA were consecutively selected from January 2016 to May 2018 for this prospective *** 73 joints were examined by X-ray,CT,and MRI within 2 *** MRI scores of the joints were determined by the International Prophylaxis Study Group(IPSG)*** CT findings were quantified according to the IPSG standard,except for cartilage injury,which was quantified by joint space narrowing using the X-ray Pettersson *** CT and MRI scores were compared by the paired Wilcoxon signed-rank *** correlations between the CT score of joint space narrowing and MRI score of cartilage injury and the total CT and MRI scores were analyzed by Spearman rank *** kappa test was used to compare the consistency of CT and MRI ***:MRI was superior to CT based on the scores for small amount of effusion(P0.05),and there was a high degree of consistency between the two scores(kappa>0.81).The consistency between the Pettersson scores of joint space narrowing on CT and the IPSG scores of cartilage injury on MRI was high(kappa=0.774,P<0.05).Conclusion:The image scores of MSCT are generally consistent with MRI except for mild synovitis,which can be used as an alternative for the evaluation of HA.

关键词： Hemophilia Arthritis Magnetic resonance imaging Computed tomography Radiography Comparative evaluation

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胃肠道间质瘤的CT检查表现

中华消化外科杂志 2012年第3期11卷 235-238页

作者：朱绍成程天明李攀河南省人民医院放射科郑州450003

1983年，Mazur和Clark首次提出胃肠道间质瘤（gastrointestinal stromal tumor，GIST）的概念。随着分子生物学、免疫组织化学以及电镜技术的发展，GIST已被证实是一类来源于胃肠道原始间叶组织、原癌基因c—kit阳性的梭形细胞或上皮细... 详细信息

1983年，Mazur和Clark首次提出胃肠道间质瘤（gastrointestinal stromal tumor，GIST）的概念。随着分子生物学、免疫组织化学以及电镜技术的发展，GIST已被证实是一类来源于胃肠道原始间叶组织、原癌基因c—kit阳性的梭形细胞或上皮细胞样肿瘤。

关键词：胃肠道间质肿瘤体层摄影术 X线计算机

“军事预防医学”新学科的创建与八年教学实践

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中国高等医学教育 2006年第8期 47-49,77页

作者：程天民第三军医大学重庆400038

将“三防医学”(防原医学、防化医学、防生物危害医学)与军队卫生学(包括军事劳动卫生学、军队环境卫生学和军队营养与食品卫生学)等学科内容扩展组合为“军事预防医学”新学科。此后的八年教学实践,实现了创建新学科、编著新教材、开... 详细信息

将“三防医学”(防原医学、防化医学、防生物危害医学)与军队卫生学(包括军事劳动卫生学、军队环境卫生学和军队营养与食品卫生学)等学科内容扩展组合为“军事预防医学”新学科。此后的八年教学实践,实现了创建新学科、编著新教材、开设新课程的教学改革系统工程,使全军预防医学领域研究生显著地增加了培养数量,提高了培养质量,促进了学科的发展和高层次人才队伍的建设,对提高我国军事预防医学学术水平,推进预防医学防疫事业和增强国防卫勤保障能力,发挥了重要的作用。此项教学改革获2005年军队教学成果一等奖和国家教学成果二等奖。

关键词：教学改革军事预防医学学科建设教学成果第三军医大学

Homologous CoS2 interface with directed electron transfer and strong chloridion repulsion for efficient seawater oxidation

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Science China Chemistry 2025年

作者： Yuan tian Jiang-Bo Chen Jie Ying Ge tian Yu-Xuan Xiao Yi Lu Si-ming Wu Wei Geng Ling Shen Xiao-Yu Yang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing and School of Materials Science and Engineering and Shenzhen Research Institute & Laoshan Laboratory Wuhan University of Technology School of Chemical Engineering and Technology Sun Yat-Sen University National Energy Key Laboratory for New Hydrogen-Ammonia Energy Technologies Foshan Xianhu Laboratory

Seawater electrolysis is a highly promising method to produce high energy density hydrogen,especially in dry areas that have scarce freshwater ***,application of seawater electrolysis is confronted by two major problems associated with catalysts employed for the anodic oxygen evolution reaction （OER） including the competitive hypochlorite evolution reaction（HCER） and strong chloridion （Cl–） triggered *** studies aimed at overcoming these problems,a facile method has been developed to synthesize a homologous CoS2heterojunction as an OER *** to a difference in work functions at the interface and increased electron density,this material has directed electron transfer and strong chloridion repulsion properties,*** have shown that CoS2achieves low overpotentials of 289 and 322 mV at 10 mA cm-2current density in respective alkaline （1 M KOH） and alkaline simulated seawater ***,the outstanding stability of CoS2is reflected in a negligible decline in activity during promotion of the OER for 100 *** of density functional theory calculations reveal that the homologous CoS2heterojunction promotes directed electron transport for optimizing adsorption/desorption of reactive species and heightens the Cl-adsorption energy for strongly repulsing Cl-,phenomena that enhance OER performance in alkaline simulated seawater.

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不同病理类型脊柱骨肿瘤的X线、CT及MRI的影像征象特点及诊断价值

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中国CT和MRI杂志 2018年第4期16卷 138-142页

作者：李锋程天明河南省新乡市中心医院CT室河南新乡453000 河南省人民医院放射科河南郑州450000

目的分析不同病理类型脊柱骨肿瘤X线、CT、MRI影像征象特点及诊断价值。方法回顾性分析2011年3月-2016年7月我院收治的52例脊柱骨肿瘤患者的临床资料,所有患者入院后均完成X线、CT、MRI检查,总结不同病理类型脊柱骨肿瘤患者影像学特点... 详细信息

目的分析不同病理类型脊柱骨肿瘤X线、CT、MRI影像征象特点及诊断价值。方法回顾性分析2011年3月-2016年7月我院收治的52例脊柱骨肿瘤患者的临床资料,所有患者入院后均完成X线、CT、MRI检查,总结不同病理类型脊柱骨肿瘤患者影像学特点。结果 (1)本组良性骨肿瘤13例,主要分布于腰椎,其次为颈椎、胸椎,以血管瘤、纤维结构不良常见;中间性骨肿瘤15例,主要分布于胸椎、腰椎,以骨母细胞瘤、骨巨细胞瘤、朗格汉斯细胞组织细胞增多症多见;恶性骨肿瘤34例,主要分布于胸椎,其次为腰椎,以浆细胞骨髓瘤、非霍奇金淋巴瘤常见。(2)MRI诊断不同病理类型脊柱骨肿瘤准确率最高(76.92%、80.00%、83.33%),其次为CT(61.54%、73.33%、75.00%),其中MRI诊断整体准确率(80.77%)高于X线(55.77%)(P<0.05)。结论 MRI对不同病理类型脊柱骨肿瘤诊断准确率最高,对X线、CT无法确诊脊柱骨肿瘤可进一步进行MRI筛查,以减少漏诊,为临床治疗奠定影像学依据。

关键词：脊柱骨肿瘤 MRI X线 CT 病理诊断

Ni-catalyzed cross-electrophile alkyl-alkyl coupling reactions

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Science China Chemistry 2025年

作者： Li-Xu You Lan tian Chun-Ling Guo Shun-Xi Li Yu-cheng Liu Yu-Long Li Wei Shu College of Chemistry and Environmental Engineering Key Laboratory of Green Catalysis of Higher Education Institutes of Sichuan Sichuan University of Science and Engineering Guangming Advanced Research Institute Shenzhen Grubbs Institute Department of Chemistry and Guangdong Provincial Key Laboratory of Catalysis Southern University of Science and Technology

Introducing saturated carbon-carbon bonds into organic molecules significantly increases the three-dimensional configuration,thus altering the physical and chemical properties as well as the functions of molecules. Transition-metal-catalyzed carboncarbon cross-couplings represent one of the most straightforward, efficient and modular alternatives to build saturation in a single step. However, the efficient construction of alkyl-alkyl bonds remains a formidable challenge due to the precise manipulation of multiple alkyl metallic intermediates as well as associated competitive side reactions and selectivity control. Over the past years, Ni-catalyzed cross-coupling under reductive conditions has gained more and more attention for alkyl-alkyl crosscoupling partially attributing to the low-valent state of metal centers under reducing conditions, which suppresses the competitive β-hydride elimination process, thus facilitating the formation of alkyl-alkyl bonds. In this review, the initiative and progress of Ni-catalyzed cross-electrophile alkyl-alkyl cross-coupling, including the efforts in racemic and enantioselective formation of alkyl-alkyl bonds, have been summarized and discussed. Moreover, the challenges and further opportunities in this area have also been discussed.

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腰椎多层螺旋CT容积扫描的临床应用

中华放射学杂志 2008年第11期42卷 1137-1142页

作者：王玲葛英辉朱绍成张明程天明雷志丹吕传剑孙晓平武明辉郭溁马千里温泽迎河南省人民医院放射科郑州450003

目的探讨腰椎多层螺旋CT容积（VH）扫描的临床应用价值。方法按就诊顺序抽取1000例腰腿痛患者，腰椎VH模式扫描患者模拟重建常规单层（SS）L3～4、L4—5、L5-S1椎间盘层面。VH扫描模式参数为120kV，210mAs，螺距1．5，平均扫描范围97．... 详细信息

目的探讨腰椎多层螺旋CT容积（VH）扫描的临床应用价值。方法按就诊顺序抽取1000例腰腿痛患者，腰椎VH模式扫描患者模拟重建常规单层（SS）L3～4、L4—5、L5-S1椎间盘层面。VH扫描模式参数为120kV，210mAs，螺距1．5，平均扫描范围97．5mm。SS扫描模式参数为120kV、240mAs、扫描范围为45．0mm。比较2种扫描模式对腰椎疾病征象显示的差异及辐射剂量的不同。对所获数据进行配对资料X^2检验和一致性检验分析。结果VH扫描模式比SS扫描模式显示更多的征象，骨性椎管狭窄、椎间隙变窄、椎间盘脱出、侧隐窝狭窄、椎体病变、L5横突肥大、椎小关节方向异常、椎小关节退行性变、椎弓峡部裂、椎旁软组织异常的检出率，VH分别为11．8％（118例）、38．5％（385例）、9．3％（93例）、46．8％（468例）、31．4％（314例）、5．7％（57例）、25．4％（254例）、49．7％（497例）、9．9％（99例）、0．6％（6例），ss分别为5．6％（56例）、0、0．6％（6例）、27．9％（279例）、22．4％（224例）、1．2％（12例）、16．7％（167例）、37．2％（372例）、0．5％（5例）、0．2％（2例），2种模式下对每一种测量指标比较除椎旁软组织异常两者差异无统计学意义（P〉0．05）外，其余测量指标差异均有统计学意义（P值均〈0．05）。与ss扫描模式相比，VH扫描模式下的骨性椎管狭窄、椎间隙变窄、椎间盘脱出和椎弓峡部裂的检出率分别提高6．2％（62例）、38．5％（385例）、8。7％（87例）和9．4％（94例），只能部分显示椎小关节面及方向、侧隐窝狭窄、L5横突肥大和椎旁软组织异常。46．7％（467例）（腰骶角〉35°）的患者SS扫描模式下的定位线不能与椎间盘层面一致。VH扫描模式（164．9mGy／cm）比SS扫描模式（147．0mGy／cm）辐射剂量稍有增加。结论腰椎多层螺旋CT VH扫描模式比SS扫描模式可以显示更多腰椎病变征象，且不受扫描架限制，辐射剂量增加不多。

关键词：腰椎脊柱疾病体层摄影术,X线计算机

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传统教育仪式的作用机理及当代启示

齐齐哈尔大学学报（哲学社会科学版） 2023年第5期 45-49页

作者：程天明王义德黄山学院马克思主义学院安徽黄山245041 安徽师范大学法学院安徽芜湖241000

中国传统教育仪式是中国古代教育制度的重要组成部分,是中国古代宣教以儒家思想为核心的主流意识形态的重要载体,是中华传统文化的重要体现。从仪式理论出发,分析传统教育仪式的象征符号、仪式空间和政治控制,探析以释奠礼、拜师礼、视... 详细信息

中国传统教育仪式是中国古代教育制度的重要组成部分,是中国古代宣教以儒家思想为核心的主流意识形态的重要载体,是中华传统文化的重要体现。从仪式理论出发,分析传统教育仪式的象征符号、仪式空间和政治控制,探析以释奠礼、拜师礼、视学礼为代表的传统教育仪式的发生机理,寻找古今仪式育人的同频共振点,为传统教育仪式的创造性转化和创新性发展提供路径选择,为新时代高校开展思想政治教育仪式提供启示和借鉴。

关键词：传统教育仪式象征符号仪式空间仪式育人

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Modular assembly of complex C-alkyl glycoside enabled via cooperative NHC and photoredox catalysis

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Science China Chemistry 2025年

作者： Rui-Qiang Jiao ming Li Xi Chen Mei-Ze Xu tian Ding Xiao-Ping Gong Zhuo-Mei Li Xue-Yuan Liu Yong-Min Liang State Key Laboratory of Applied Organic Chemistry Lanzhou University College of Chemistry and Chemical Engineering Northwest Normal University

C-Alkyl glycosides are found in natural products and are indispensable in drug development programs,owing to their diverse range of medicinal ***-component reactions involving glycosyl radical addition are well documented and proved efficient for the C-alkyl glycosides ***,multicomponent reactions for the rapid and controllable construction of structurally diversified C-alkyl glycosides in a single step remains a significant challenge due to the issues associated with balancing reactivity,compatibility,and ***,we report an NHC and photoredox co-catalyzed three-component method to access complex and valuable C-alkyl *** protocol exhibits broad substrate scope and excellent chemoand ***,nine types of sugars are compatible with this *** addition,the generality of this catalytic strategy was further highlighted by the potential for scalable production,the feasibility of further modifications of the products and its successful application in the late-stage functionalization of pharmaceutical skeletons.

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