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In Vivo Fast Induction of Homogeneous Autopolyploids via Callus in Sour Jujube(Ziziphus acidojujuba cheng et liu)

Horticultural Plant Journal 2016年第3期2卷 147-153页

作者： SHI Qinghua liu Ping liu Mengjun WANG Jiurui ZHAO Jin ZHAO Zhihui DAI Li Research Center of Chinese Jujube Agricultural University of Hebei College of Forestry Agricultural University of Hebei College of Life Science Agricultural University of Hebei

Polyploidization has been demonstrated as a very effective approach in fruit tree *** jujube(Ziziphus acidojujuba cheng et liu) is a promising diploid wild,traditional fruit species(2n = 2x = 24) that is rich in vitamin C,which is the main rootstock of Chinese jujube(*** Mill.).The novel method we developed for rapid in vivo induction of homogeneous autopolyploids(IVIHA) via callus in Chinese jujube was first applied and further optimized in sour *** optimized conditions,an average of one pure autotetraploid shoot could be regenerated from one treated branch,thereby indicating a relatively high efficiency rate.A total of 9 pure autotetraploid genotypes were created,and one of these was released as a new cultivar named ‘Zhuguang' in ***,unexpected octoploids and hexaploids were also simultaneously created and *** leaves of tetraploids were thicker,broader,and darker in color than those of the original diploids,whereas the leaf sizes of octoploids were much smaller compared to that of ***,stoma size increased with the occurrence of ploidy,mainly from diploid to *** well grown ploidies of jujube included diploids,triploids,and *** observation indicated that adventitious buds/shoots emerged from the callus that formed on the cut,which was then followed by the development of connective vascular tissues between the adventitious bud and the stock plant *** study demonstrates the universality of the IVIHA method that was initially developed in Chinese jujube,as well as provides a foundation for high-efficiency pure polyploid induction in sour jujube.

关键词： sour jujube in vivo callus homogeneous autopolyploid tetraploid hexaploid octoploid

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Herpes simplex virus 2-induced aseptic meningitis presenting with sudden deafness:A case report

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World Journal of Clinical Cases 2025年第8期13卷 22-25页

作者： Yuan-cheng liu Shih-Hsuan Hsiao Peir-Rong Chen Department of Otolaryngology Hualien Tzu Chi HospitalHualien 970TaiwanChina Department of Otolaryngology Hualien Tzu Chi Hospitaland Department of OtolaryngologyHead and Neck SurgerySchool of MedicineTzu Chi UniversityHualien 970TaiwanChina

BACKGROUND Aseptic meningitis is defined as meningeal inflammation caused by various etio-logies with negative cerebrospinal fluid(CSF)bacterial *** most common etiologies are viruses[enteroviruses,arboviruses,and herpes simplex virus type 2(HSV-2)].Aseptic meningitis can have various presentations,including sensori-neural *** sensorineural deafness from mumps meningoencephalitis has been reported,cases of HSV-2-induced hearing loss are ***,we re-port a case of HSV-2-induced meningitis that presented with sudden *** SUMMARY A 68-year-old man experienced a profound sudden onset of left-sided hearing loss for one ***-tone audiograms demonstrated sudden left-sided sensorineural hearing loss(thresholds 80-90 dB).After treatment with high-dose steroids for 1 week,he experienced an acute consciousness change with left *** laboratory data showed no significant *** computed tomography without contrast and magnetic resonance imaging revealed no intracranial hemo-rrhage or obvious brain *** CSF analysis and the Multiplex PCR panels showed HSV-2 ***,under the diagnosis of herpes meningoenceph-alitis,acyclovir was prescribed and his symptoms gradually *** This case report further demonstrates that a viral infection could be a cause of sudden sensorineural hearing loss.

关键词： Aseptic meningitis Type 2 herpes simplex Sudden sensorineural hearing loss Immunocompromised Cerebrospinal fluid Case report

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思想政治教育数字化的价值意蕴及实践进路

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新疆师范大学学报（哲学社会科学版） 2025年第2期46卷 128-136页

作者：于祥成刘成合肥工业大学安徽合肥230009 武汉大学马克思主义学院湖北武汉430064

随着数字技术的广泛应用和教育数字化转型发展,数字化变革成为思想政治教育创新发展的必然选择。面对新的时代境遇,要全面把握思想政治教育数字化的内涵和特征,深刻认识思想政治教育数字化在推动思想政治教育认知重建、资源重组、话语... 详细信息

随着数字技术的广泛应用和教育数字化转型发展,数字化变革成为思想政治教育创新发展的必然选择。面对新的时代境遇,要全面把握思想政治教育数字化的内涵和特征,深刻认识思想政治教育数字化在推动思想政治教育认知重建、资源重组、话语重构、形态重塑等方面的重要价值。同时,要秉承数字理念,构建思想政治教育数字范式;搭建数字平台,优化思想政治教育数字服务;培育数字素养,提升思想政治教育数字技能;厚植“数字土壤”,形塑思想政治教育数字生态,积极探索思想政治教育数字化实践创新路径。

关键词：思想政治教育数字化数字技术实践进路

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Improved concept models for straight thin-walled columns with box cross section

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第11期9卷 1473-1479页

作者： Yu-cheng liu Department of Mechanical Engineering University of Louisville Louisville KY40292 USA

This paper focuses on developing improved concept models for straight thin-walled box sectional columns which can better predict the peak crushing force that occurs during crashworthiness analyses. We develop a nonlinear translational spring based on previous research and apply such a spring element to build the enhanced concept models. The work presented in this article is developed on the basis of the publication of the author (liu and Day, 2006b) and has been applied in a crashworthiness design issue, which is presented by the author in another paper (liu, 2008).

关键词： Concept model Peak crushing force Box section Nonlinear translational springs Crashworthiness analysis Thin-walled column

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Simulation of violent free surface flow by AMR method

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Journal of Hydrodynamics 2018年第3期30卷 384-389页

作者： Changhong Hu cheng liu Research Institute for Applied Mechanics Kyushu University Fukuoka Japa

A novel CFD approach based on adaptive mesh refinement（AMR） technique is being developed for numerical simulation of violent free surface flows. CIP method is applied to the flow solver and tangent of hyperbola for interface capturing with slope weighting（THINC/SW） scheme is implemented as the free surface capturing scheme. The PETSc library is adopted to solve the linear system. The linear solver is redesigned and modified to satisfy the requirement of the AMR mesh topology. In this paper, our CFD method is outlined and newly obtained results on numerical simulation of violent free surface flows are presented.

关键词： Adaptive mesh refinement CIP method parallel computation violent free surface flow

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Exactly solving some typical Riemann-Liouville fractional models by a general method of separation of variables

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Communications in Theoretical Physics 2020年第5期72卷 46-51页

作者： cheng-Shi liu Department of Mathematics Northeast Petroleum UniversityDaqing 163318China

Finding exact solutions for Riemann–Liouville(RL)fractional equations is very *** propose a general method of separation of variables to study the *** obtain several general results and,as applications,we give nontrivial exact solutions for some typical RL fractional equations such as the fractional Kadomtsev–Petviashvili equation and the fractional Langmuir chain *** particular,we obtain non-power functions solutions for a kind of RL time-fractional reaction–diffusion *** addition,we find that the separation of variables method is more suited to deal with high-dimensional nonlinear RL fractional equations because we have more freedom to choose undetermined functions.

关键词： Riemann–Liouville derivative exact solution fractional differential equation separation of variables method

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残余胆固醇与进展为主要不良心血管事件的非罪犯病变易损斑块的相关性研究

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中国全科医学 2025年第3期28卷 299-304页

作者：杨红刘成刘森邵琪琪夭元昊付真彦新疆医科大学第一附属医院心脏中心新疆维吾尔自治区乌鲁木齐市830054

背景残余胆固醇(RC)被认为是动脉粥样硬化性心血管疾病的重要危险因素,而冠状动脉非罪犯病变(NCCLs)进展也是影响冠心病患者预后的重要因素,但是残余胆固醇与进展为主要不良心血管事件(MACE)的NCCLs易损斑块的关系尚不明确。目的探讨R... 详细信息

背景残余胆固醇(RC)被认为是动脉粥样硬化性心血管疾病的重要危险因素,而冠状动脉非罪犯病变(NCCLs)进展也是影响冠心病患者预后的重要因素,但是残余胆固醇与进展为主要不良心血管事件(MACE)的NCCLs易损斑块的关系尚不明确。目的探讨RC对发生MACE的NCCLs易损斑块的预测价值及长期预后的相关性。方法选取2015年2月—2022年2月于新疆医科大学第一附属医院心脏中心住院的488例冠心病患者为研究对象,通过电子病历系统收集患者基线资料,行冠状动脉造影及光学相干断层扫描OCT。入组患者在出院1、3、6和12个月接受预定随访。采用Spearman秩相关检验探究RC与NCCLs中薄纤维帽粥样硬化斑块(TCFA)斑块特征的相关性。采用多因素Logistic回归分析探究NCCLs中TCFA发生MACE的影响因素。绘制受试者工作特征曲线(ROC曲线)并计算ROC曲线下面积(AUC),探究RC对NCCLs中TCFA发生MACE的预测价值。结果共纳入488例冠心病患者,根据NCCLs是否发生MACE将患者分为发生MACE组(n=38)和未发生MACE组(n=450)。通过OCT识别NCCLs的斑块特征,共分析了749个NCCLs斑块,304个NCCLs斑块最小管腔面积(MLA)<3.5 mm^(2)。随访期间38例(7.8%)患者共发生了41例次NCCLs斑块引起的MACE事件,18例(3.7%)患者发生了支架内再狭窄,15例(3.1%)发生了不确定因素的死亡。发生MACE组患者高血压、糖尿病、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、RC、糖化血红蛋白(Hb A1c)、TCFA、MLA<3.5 mm^(2)比例高于未发生MACE组(P<0.05)。105例患者检查出TCFA,其中22例发生MACE(发生MACE的TCFA组),83例未发生MACE(未发生MACE的TCFA组)。发生MACE的TCFA组糖尿病比例与RC高于未发生MACE的TCFA组(P<0.05)。Spearman秩相关分析结果示,RC与最薄纤维帽厚度、MLA呈负相关(r_(s)=-0.665、-0.771,P<0.05),与最大脂质弧度、巨噬细胞浸润呈正相关(r_(s)=0.806、0.481,P<0.05)。多因素Logistic回归分析结果显示糖尿病(OR=3.410,95%CI=1.165~9.988,P=0.025)、高RC水平(OR=5.879,95%CI=1.436~24.073,P=0.014)是NCCLs中TCFA发生MACE的危险因素。绘制RC预测NCCLs中TCFA发生MACE的ROC曲线,结果显示AUC为0.695(95%CI=0.571~0.819,P=0.005),最佳截断值为0.606 mmol/L,灵敏度、特异度分别为0.818、0.518。结论 RC水平升高可能是冠心病患者中NCCLs易损斑块发生MACE的危险因素,对NCCLs中TCFA发生MACE有一定的预测价值。

关键词：冠心病冠状动脉粥样硬化血脂异常主要不良心血管事件冠状动脉非罪犯病变残余胆固醇相关性研究

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Vortical structures and wakes of a sphere in homogeneous and density stratified fluid

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Journal of Hydrodynamics 2021年第2期33卷 207-215页

作者： liu-shuai Cao Feng-lai Huang cheng liu De-cheng Wan Computational Marine Hydrodynamics Lab(CMHL) School of Naval ArchitectureOcean and Civil Engi-neeringShanghai Jiao Tong UniversityShanghai 200240China Ocean College Zhejiang UniversityZhoushan 316021China

Vortical structures and wakes of bluff bodies in homogenous and stratified environment are common and important in ocean *** on the Boussinesq approximation,a thermocline model is proposed to deal with the variable density stratified fluid,and implemented in the commercial software Simcenter STAR-CCM+*** improved delayed detached eddy simulation(IDDES)modeling method is adopted to resolve the coherent vortical structures and turbulent wakes precisely and *** conditions consisting of one homogenous and three stratified fluid cases with different density gradient past a sphere at Reynolds number 3700 are *** show that density stratification has a great impact on the vortical structures,the vertical motion is suppressed and internal waves will be induced and propagated,which is very different with that of homogenous *** the stratification strength increases,the vortical structures are gradually flattened,the asymmetry and anisotropy between vertical and horizontal motions are enhanced.

关键词： Vortical structures wakes sphere homogenous stratified fluid

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CFD simulation of tidal current farm by using AL model

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Journal of Hydrodynamics 2019年第1期31卷 34-40页

作者： cheng liu Changhong Hu Research Institute for Applied Mechanics Kyushu UniversityFukuokaJapan

In this study,an efficient numerical method for predicting the wake interference of multiple turbines is *** actuator line (AL) model instead of the geometry-resolved method is adopted to represent the *** large-eddy simulation (LES) is performed to predict wakes of multiple turbines operated in turbulent *** efficient immersed boundary (IB) method with moving least square reconstruction (MLS) is developed to model the nacelle and support structure of the tidal turbine.A simple wall function based on the MLS-IB method and boundary-layer equations is employed to compute the instantaneous wall shear *** flow simulations of unsteady flows past a cylinder illustrate the accuracy of the wall function IB ***,the proposed method is extended to study turbulent flow past tandem tidal rotors,in which the wake profile behind rotors is *** results are found to be in reasonable agreement with published data.

关键词： Tidal current farm immersed boundary method wall fimction model large eddy simulation (LES) actuator line model

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Development of Cartesian grid method for simulation of violent ship-wave interactions

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Journal of Hydrodynamics 2016年第6期28卷 1003-1010页

作者： Changhong HU cheng liu Research Institute for Applied Mechanics Kyushu University

We present a Cartesian grid method for numerical simulation of strongly nonlinear phenomena of ship-wave interactions. The Constraint Interpolation Profile （CIP） method is applied to the flow solver, which can efficiently increase the discretization accuracy on the moving boundaries for the Cartesian grid method. Tangent of Hyperbola for Interface Capturing （THINC） is imple- mented as an interface capturing scheme for free surface calculation. An improved immersed boundary method is developed to treat moving bodies with complex-shaped geometries. In this paper, the main features and some recent improvements of the Cartesian grid method are described and several numerical simulation results are presented to discuss its performance.

关键词： strongly nonlinear wave-body interaction Cartesian grid method CIP method

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