检索结果-南通市图书馆

A Chinese Multi-Specialty Delphi Consensus to Optimize RAASi Usage and Hyperkalaemia Management in Patients with Chronic Kidney Disease and Heart Failure

引用

Chinese Medical Sciences Journal 2024年第2期39卷 79-90页

作者： Ming-Hui Zhao Wei Chen Hong cheng bi-cheng Liu Zhi-Guo Mao Zhuang Tian Gang Xu Jing-Min Zhou Renal Division Peking University First HospitalBeijing 100034China Department of Nephrology The First Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510080China Department of Nephrology Capital Medical UniversityBeijing 100029China Department of Nephrology Southeast University Zhongda HospitalNanjing 210009China Department of Nephrology Shanghai Changzheng HospitalShanghai 200003China Department of Cardiology Peking Union Medical College HospitalBeijing 100730China Renal Division Tongji Medical College of Huazhong University of Science and TechnologyWuhan 430030China Department of Cardiology Zhongshan HospitalFudan UniversityShanghai 200032China

Objective Variations are present in common clinical practices regarding best practice in managing hyperkalaemia(HK),there is therefore a need to establish a multi-specialty approach to optimal renin angiotension-aldosterone system inhibitors(RAASi)usage and HK management in patients with chronic kidney disease(CKD)&heart failure(HF).This study aimed to establish a multi-speciality approach to the optimal use of RAASi and the management of HK in patients with CKD and HF.Methods A steering expert group of cardiology and nephrology experts across China were convened to discuss challenges to HK management through a nominal group technique.The group then created a list of 41 statements for a consensus questionnaire,which was distributed for a further survey in extended panel group of cardiologists and nephrologists across China.Consensus was assessed using a modified Delphi technique,with agreement defined as"strong"(≥75%and<90%)and"very strong"(≥90%).The steering group,data collection,and analysis were aided by an independent facilitator.Results A total of 150 responses from 21 provinces across China were recruited in the survey.Respondents were comprised of an even split(n=75,50%)between cardiologists and nephrologists.All 41 statements achieved the 75%consensus agreement threshold,of which 27 statements attained very strong consensus(≥90%agreement)and 14 attained strong consensus(agreement between 75%and 90%).Conclusion Based on the agreement levels from respondents,the steering group agreed a set of recommendations intended to improve patient outcomes in the use of RAASi therapy and HK management in China.

关键词： Sardiorenal syndrome chronic kidney failure heart failure hyperkalemia multidisciplinary communication RAASi

来源：

维普期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Translational Informatics for Parkinson’s Disease:from big biomedical Data to Small Actionable Alterations

引用

Genomics, Proteomics & bioinformatics 2019年第4期17卷 415-429页

作者： Bairong Shen Yuxin Lin cheng bi Shengrong Zhou Zhongchen Bai Guangmin Zheng Jing Zhou Institutes for Systems Genetics West China HospitalSichuan UniversityChengdu 610041China Center for Systems biology Soochow UniversitySuzhou 215006China Center for Translational biomedical Informatics Guizhou University School of MedicineGuiyang 550025China

Parkinson’s disease(PD)is a common neurological disease in elderly people,and its morbidity and mortality are increasing with the advent of global ageing.The traditional paradigm of moving from small data to big data in biomedical research is shifting toward big data-based identification of small actionable alterations.To highlight the use of big data for precision PD medicine,we review PD big data and informatics for the translation of basic PD research to clinical applications.We emphasize some key findings in clinically actionable changes,such as susceptibility genetic variations for PD risk population screening,biomarkers for the diagnosis and stratification of PD patients,risk factors for PD,and lifestyles for the prevention of PD.The challenges associated with the collection,storage,and modelling of diverse big data for PD precision medicine and healthcare are also summarized.Future perspectives on systems modelling and intelligent medicine for PD monitoring,diagnosis,treatment,and healthcare are discussed in the end.

关键词： Parkinson’s disease Healthcare Disease biomarker Translational informatics Systems modelling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An improved mathematical model to simulate mold filling process in high pressure die casting using CLSVOF method and CSF model

引用

China Foundry 2015年第3期12卷 180-188页

作者： cheng bi Zhi-peng Guo Shou-mei Xiong School of Materials Science and Engineering Tsinghua University

A 3D mathematical model was proposed to simulate the mold filling process in high-pressure die casting(HPDC) to improve accuracy considering the surface tension. Piecewise liner interface calculation(PLIC) and volume of fluid(VOF) methods were used to construct the pattern of the liquid interface. A coupled levelset and VOF method(CLSVOF) was proposed to capture the interface pattern and obtain its normal vector. A continuum surface force(CSF) model was used to consider the surface tension. Two water analogy experiments were carried out using the proposed model. Simulation and experimental results were analyzed and compared; and the effects of surface tension were also discussed. The simulation results agreed well with the experiments and the simulation accuracy was an improvement on interface geometries, liquid flows, and gas entrapments.

关键词： mold filling HPDC CLSVOF CSF surface tension force

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Incidence and risk factor analysis for swelling after apical microsurgery

引用

World Journal of Clinical Cases 2022年第26期10卷 9303-9309页

作者： cheng bi Si-Qi Xia Yu-Chi Zhu Xin-Zhu Lian Li-Jun Hu Chen-Xing Rao Hai-bin Jin Xiao-Dan Shang Fei-Fan Jin Jing-Yu Li Pei Zheng Shu-Hua Wang School of Stomatology Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina VIP Center Hangzhou Stomatology HospitalHangzhou 310006Zhejiang ProvinceChina

BACKGROUND Swelling after apical microsurgery is a postoperative reaction and may reduce quality of life during healing.AIM To evaluate periapical swelling after apical microsurgery and determine potential risk factors.METHODS Ninety-eight apical microsurgery patients were selected for this study.Before surgery,bone shadow volume and density of pathological tissue were measured by cone beam computed tomography.The other variables(age,gender,operative teeth number,fistula,preoperative swelling,drug use and preoperative root canal treatments)were assessed during examination.Swelling degree was confirmed by questionnaires for patients on postoperative days 1,7,14 and 21.Statistical analyses were performed to identify predictors for swelling.RESULTS Majority of patients reported moderate(45.9%)or severe(34.7%)swelling on day 1,and moderate(44.9%)or mild(45.9%)on postoperative day 7.Ninety-nine percent of patients had no or mild swelling on postoperative day 14.The average swelling level peaked on day 1 postoperatively and gradually decreased.Of statistical significance,age,bone shadow volume and density of pathological tissue acted as predictors of swelling(P0.05).CONCLUSION Younger patients with larger shadow volume and density were significantly more likely to develop swelling after apical microsurgery.

关键词： Apical microsurgery Swelling Incidence Risk factor Prognosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficient preparation of β-hydroxy aspartic acid and its derivatives

引用

Chinese Chemical Letters 2018年第7期29卷 1113-1115页

作者： Long Liu Bo Wang cheng bi Gang He Gong Chen State Key Laboratory and Institute of Elemento-Organic Chemistry College of Chemistry Nankai University Tianjin 300071 China Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin 300071 China

We report an efficient and practical synthetic route to various properly-protected erythreo-β-OH-Asp compounds, which are key β-branched a-amino acid units in coralmycin A and other peptide natural products. Fmoc and cyclic ketal-protected erythreo-β-OH-Asp 7 is prepared from cheap chiral precursor L-diethyl tortrate in six steps without the need of column purification. The modified form of 7 serves as a versatile precursor to various β-alkoxyl analogs of erythreo-β-OH-Asp. In addition, we successfully performed a model study toward the total synthesis of coralmycin A, featuring a late stage installation of the side chain primary amide group of erythreo-β-OMe-Asn.

关键词： Amino acid Natural product Erythreo-β-OH-Asp Erythreo-β-OMe-Asn Antibiotics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

一个涉及高阶导函数的Hardy-Hilbert型积分不等式

引用

五邑大学学报（自然科学版） 2024年第1期38卷 12-22页

作者：杨必成广东第二师范学院数学学院广东广州510303

应用权函数方法、参量化思想及实分析技巧,建立一个新的齐次核为1/(x+y)^(λ+m+n)(λ>0)的涉及高阶导函数的Hardy-Hilbert型积分不等式,求出了联系该式的最佳常数因子及多参数的等价陈述.作为推论,还求出了特殊条件下该不等式的等价形... 详细信息

应用权函数方法、参量化思想及实分析技巧,建立一个新的齐次核为1/(x+y)^(λ+m+n)(λ>0)的涉及高阶导函数的Hardy-Hilbert型积分不等式,求出了联系该式的最佳常数因子及多参数的等价陈述.作为推论,还求出了特殊条件下该不等式的等价形式、非齐次核的情形及算子表示,并导出了若干特例.

关键词：权函数 Hardy-Hilbert型积分不等式高阶导函数 beta函数

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

非遗语境下茶文化对外传播的方法与路径探索

引用

中国茶叶 2024年第2期46卷 74-82页

作者：张帅毕程浙江农林大学茶学与茶文化学院浙江杭州311300

近年来,我国茶文化对外传播取得了明显进展,但也面临着特定文化语境缺失与被误读等问题。文章在充分认识我国茶文化对外传播现状的基础上,强调了在“中国传统制茶技艺及其相关习俗”列入联合国教科文组织人类非物质文化遗产代表作名录... 详细信息

近年来,我国茶文化对外传播取得了明显进展,但也面临着特定文化语境缺失与被误读等问题。文章在充分认识我国茶文化对外传播现状的基础上,强调了在“中国传统制茶技艺及其相关习俗”列入联合国教科文组织人类非物质文化遗产代表作名录的契机下,以非物质文化遗产为媒介传播茶文化的优势与意义,并从构建茶文化对外传播话语体系、创建茶文化传播资源集群、搭建茶文化传播交流平台等方面提出了具体的路径与方法。

关键词：茶文化非遗传承对外传播中国传统制茶技艺及其相关习俗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Generating Giant Membrane Vesicles from Live Cells with Preserved Cellular Properties

引用

Research 2019年第1期2019卷 859-867页

作者： Qiaoling Liu cheng bi Jiangling Li Xuejiao Liu Ruizi Peng cheng Jin Yang Sun Yifan Lyu Hui Liu Huijing Wang Can Luo Weihong Tan Molecular Science and biomedicine Laboratory(MBL) State Key Laboratory of Chemo/Bio-Sensing and ChemometricsCollege of BiologyCollege of Chemistry and Chemical EngineeringAptamer Engineering Center of Hunan ProvinceHunan UniversityChangshaChina Institute of Molecular Medicine(IMM) Renji HospitalShanghai Jiao Tong University School of Medicine and School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghaiChina Departments of Chemistry Physiology and Functional GenomicsMolecular Genetics and Microbiology and Pathology and Laboratory MedicineUF Health Cancer CenterCenter for Research at the Bio/Nano InterfaceUniversity of FloridaGainesvilleFLUSA

biomimetic giant membrane vesicles,with size and lipid compositions comparable to cells,have been recognized as an attractive experimental alternative to living systems.Due to the similarity of their membrane structure to that of body cells,cell-derived giant plasma membrane vesicles have been used as a membrane model for studying lipid/protein behavior of plasma membranes.However,further application of biomimetic giant membrane vesicles has been hampered by the side-efects of chemical vesiculants and the utilization of osmotic bufer.We herein develop a facile strategy to derive giant membrane vesicles(GMVs)from mammalian cells in biofriendly medium with high yields.Tese GMVs preserve membrane properties and adaptability for surface modifcation and encapsulation of exogenous molecules,which would facilitate their potential biological applications.Moreover,by loading GMVs with therapeutic drugs,GMVs could be employed for drug transport to tumor cells,which represents another step forward in the biomedical application of giant membrane vesicles.Tis study highlights biocompatible GMVs with biomimicking membrane surface properties and adaptability as an ideal platform for drug delivery strategies with potential clinical applications.

关键词： attractive similarity preserve

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

复合溶胶感光机理及点阵防腐涂层制备

引用

涂料工业 2024年第4期54卷 47-53页

作者：贠柯张澄杨旭毕成刘金娥鲁元任洋西安特种设备检验检测院西安710065 西安理工大学材料科学与工程学院西安710048

为提升20钢的耐腐蚀性,基于感光微细加工原理,采用溶胶凝胶法在20钢表面制备了具有疏水性的TiO_(2)-SiO_(2)点阵涂层,重点研究了TiO_(2)-SiO_(2)复合溶胶的感光机理,并对比了受TiO_(2)点阵涂层、TiO_(2)-SiO_(2)点阵涂层和平铺底层/TiO_... 详细信息

为提升20钢的耐腐蚀性,基于感光微细加工原理,采用溶胶凝胶法在20钢表面制备了具有疏水性的TiO_(2)-SiO_(2)点阵涂层,重点研究了TiO_(2)-SiO_(2)复合溶胶的感光机理,并对比了受TiO_(2)点阵涂层、TiO_(2)-SiO_(2)点阵涂层和平铺底层/TiO_(2)-SiO_(2)点阵涂层保护的20钢的耐腐蚀性。结果表明:TiO_(2)-SiO_(2)溶胶对330~380 nm紫外光具有优秀的感光能力,感光后的Ti4+金属鳌合物在有机溶剂中的溶解度急剧降低,因此,采用感光溶胶凝胶技术可以获得结构完整的TiO_(2)-SiO_(2)点阵涂层,使材料由亲水性向疏水性转变,并且耐腐蚀性大幅度提升,其中平铺底层/TiO_(2)-SiO_(2)点阵涂层经盐雾试验后表面没有任何腐蚀痕迹,对20钢板有很强的保护能力。

关键词：感光溶胶凝胶 20钢 TiO_(2)-SiO_(2)点阵涂层耐腐蚀性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

一个含离散型分式核的Hilbert型不等式

引用

兰州理工大学学报 2024年第3期50卷 151-155页

作者：有名辉董飞杨必成浙江机电职业技术学院数学教研室浙江杭州310053 广东第二师范学院数学学院广东广州510303

引入若干正参数,新构建了一个分式型的离散形态的核函数,并借助于权系数的方法,建立了一个二重Hilbert型级数不等式,并证明此不等式的常数因子是最佳取值.另外,根据余割函数的有理分式展开形式,给出最佳常数因子的余割函数表示形式.通... 详细信息

引入若干正参数,新构建了一个分式型的离散形态的核函数,并借助于权系数的方法,建立了一个二重Hilbert型级数不等式,并证明此不等式的常数因子是最佳取值.另外,根据余割函数的有理分式展开形式,给出最佳常数因子的余割函数表示形式.通过对参数赋予一些特殊数值,得到了一些已有结果,并且给出了一些新的含特殊核函数的Hilbert型不等式.

关键词： Hilbert型不等式分式型核函数有理分式展开余割函数

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：