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2A12航空铝合金多轴疲劳试验及应力准则寿命预测模型研究

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中国机械工程 2017年第9期28卷 1092-1096,1100页

作者：陈亚军刘波刘辰辰周剑中国民航大学中欧航空工程师学院天津300300 中国南方航空股份有限公司广州510410

针对多轴疲劳失效问题,选取2A12航空铝合金进行应力幅比变量、相位差变量和平均应力变量的多轴疲劳试验。对常用的3种多轴疲劳应力准则寿命预测模型(即Lee准则、Carpinteri准则和Sines准则)进行讨论,并通过引入应力幅比参量和相位差参量... 详细信息

针对多轴疲劳失效问题,选取2A12航空铝合金进行应力幅比变量、相位差变量和平均应力变量的多轴疲劳试验。对常用的3种多轴疲劳应力准则寿命预测模型(即Lee准则、Carpinteri准则和Sines准则)进行讨论,并通过引入应力幅比参量和相位差参量,提出基于Carpinteri准则的修正模型。将不同条件下2A12航空铝合金的试验寿命与不同应力准则下模型的预测寿命进行比较,结果表明:Lee准则对上述多轴疲劳试验的预测结果过于危险;Carpinteri准则和Sines准则由于未考虑拉-扭应力幅比和相位差因素,预测寿命与实际寿命相比均出现了较大偏差;修正后的应力准则寿命预测模型在不同条件下90%的寿命预测数据在两倍误差带内。

关键词： 2A12铝合金多轴疲劳应力准则寿命预测模型修正

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基于ARM的远程视频监控系统设计

计算机测量与控制 2012年第8期20卷 2127-2129,2132页

作者：刘尘尘西昌学院汽车与电子工程学院四川西昌615013

着眼视频监控网络化发展需求,开发了一种基于ARM的远程视频监控系统;系统的硬件以ARM S3C2440嵌入式芯片为核心,设计了硬件系统的电源、以太网接口、JTAG接口、数据存储等主要模块的电路结构;系统的软件以Linux为操作系统,利用Vide-o4Li... 详细信息

着眼视频监控网络化发展需求,开发了一种基于ARM的远程视频监控系统;系统的硬件以ARM S3C2440嵌入式芯片为核心,设计了硬件系统的电源、以太网接口、JTAG接口、数据存储等主要模块的电路结构;系统的软件以Linux为操作系统,利用Vide-o4Linux完成视频图像的采集,采用JPEG图像压缩技术实现视频的压缩处理,并用实时传输协议RTP实现对视频图像的封装和网络传输、控制;测试结果表明,该视频监控系统硬件结构小、功耗低、占用资源少,启动时间仅需20ms,网络实时视频图像传输速率达到25～30fps,实现了远程视频图像的实时网络化传输,具有一定的实用价值。

关键词：远程视频监控图像识别与跟踪图像压缩设计

Waste Activated Sludge Alkaline Fermentation Liquid as Carbon Source for Biological Nutrients Removal in Anaerobic Followed by Alternating Aerobic-Anoxic Sequencing Batch Reactors

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Chinese Journal of Chemical Engineering 2010年第3期18卷 478-485页

作者：郑雄陈银广刘晨晨 State Key Laboratory of Pollution Control and Resources Reuse School of Environmental Science and Engineering Tongji University Shanghai 200092 China Kuang Yarning Honors School Nanjing University Nanjing 210093 China

Activated sludge process has been widely used to remove phosphorus and nitrogen from wastewater. However,the nitrogen and phosphorus removal is sometimes unsatisfactory due to the low influent *** problem with the activated sludge process is that large amount of waste activated sludge is produced,which needs further *** this study,the waste activated sludge alkaline fermentation liquid was used as the main carbon source for phosphorus and nitrogen removal under anaerobic followed by alternating aerobic-anoxic conditions,and the results were compared with those using acetic acid as the carbon *** use of alkaline fermentation liquid not only affected the transformations of phosphorus,nitrogen,intracellular polyhydroxyalkanoates and glycogen, but also led to higher removal efficiencies for phosphorus and nitrogen compared with acetic *** was observed that ammonium was completely removed with either alkaline fermentation liquid or acetic acid as the carbon source. However,the former resulted in higher removal efficiencies for phosphorus(95%)and nitrogen(82%),while the latter showed lower ones(87%and 74%,respectively).The presence of a large amount of propionic acid in the alkaline fermentation liquid was one possible reason for its higher phosphorus removal *** instead of endogenous denitrification was the main pathway for nitrogen removal with the alkaline fermentation liquid as the carbon source,which was responsible for its higher nitrogen removal *** seems that the alkaline fermentation liquid can replace acetic acid as the carbon source for phosphorus and nitrogen removal in anaerobic fol- lowed by alternating aerobic-anoxic sequencing batch reactor.

关键词： nutrients removal alkaline fermentation liquid waste activated sludge endogenous denitrification carbon source

Maillard reaction affecting immunobinding activity and digestibility of tropomyosin in Alectryonella plicatula food matrix

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Food Science and Human Wellness 2024年第5期13卷 2959-2969页

作者： chenchen Yu Xinrong He Nairu Ji Shuai Kang Dongxiao Li Huilin Zhang Yang Yang Dong Lai Qingmei liu Guangming liu College of Ocean Food and Biological Engineering Xiamen Key Laboratory of Marine Functional FoodFujian Provincial Engineering Technology Research Center of Marine Functional FoodJimei UniversityXiamen 361021China The Second Affiliated Hospital of Xiamen Medical College Xiamen 361021China

In recent years,the allergy rate of oysters has surged,and daily food processing methods make it hard to reduce heat resistance and digestive allergy such as tropomyosin(TM).In this study,the Maillard reaction with xylose significantly reduced the IgE binding capacity of Alectryonella plicatula food matrix(AFM),that reduced by(77.81±2.68)%.The study found the Maillard reaction changes the structure of the AFM,in which the content ofα-helix decreased by(24.64±1.46)%.Structural transformation further explains why the Maillard reaction alters the immunobinding activity of *** addition,the Maillard reaction reduces the digestive stability of the AFM and makes TM in the *** food matrix Maillard reaction products(AFM-MRPs)more easily *** on the above research,10 amino acids on the 7 IgE epitopes of TM were *** result indicates that the Maillard reaction reduces the immunobinding activity of the AFM by changing the structure and modifying the amino acids on the epitope.

关键词： Alectryonella plicatula Food matrix Immunobinding activity Maillard reaction Tropomyosin

碳基CMOS集成电路技术:发展现状与未来挑战

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中国科学：化学 2021年第11期51卷 1457-1473页

作者：刘晨晨张志勇北京大学纳米器件物理与化学教育部重点实验室与碳基电子学研究中心北京100871

碳纳米管凭借其优良的电学性质、准一维尺寸以及稳定的结构成为后摩尔时代最理想的半导体材料.目前碳基电子学已经取得很大进展,例如可以在4寸晶圆上得到高半导体纯度(超过99.9999%)的密排(100~200 CNTs/μm)阵列碳纳米管,晶体管栅长可... 详细信息

碳纳米管凭借其优良的电学性质、准一维尺寸以及稳定的结构成为后摩尔时代最理想的半导体材料.目前碳基电子学已经取得很大进展,例如可以在4寸晶圆上得到高半导体纯度(超过99.9999%)的密排(100~200 CNTs/μm)阵列碳纳米管,晶体管栅长可以缩至5 nm且具备超越硅基的性能,世界首个碳基现代微处理器RV16XNANO已经问世.本文综述了近年来碳纳米管在材料、器件和集成电路方面的发展,以及未来可能在光电、传感、显示和射频等领域的应用前景.最后,文章列举了碳基CMOS集成电路推向产业化的过程中面临的一系列挑战,并对碳基技术发展路线做了进一步展望.

关键词：碳纳米管 CMOS晶体管集成电路纳米电子学

LncRNA IDH1-AS1 sponges miR-518c-5p to suppress proliferation of epithelial ovarian cancer cell by targeting RMB47

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The Journal of Biomedical Research 2024年第1期38卷 51-65页

作者： Juan Zhou Yiran Xu Luyao Wang Yu Cong Ke Huang Xinxing Pan Guangquan liu Wenqu Li chenchen Dai Pengfei Xu Xuemei Jia Department of Gynecology Women's Hospital of Nanjing Medical UniversityNanjing Maternity and Child Health Care HospitalNanjingJiangsu 210004China Nanjing Maternity and Child Health Medical Institute Women's Hospital of Nanjing Medical UniversityNanjing Maternity and Child Health Care HospitalNanjingJiangsu 210004China.

Long noncoding RNA(lncRNA)IDH1 antisense RNA 1(IDH1-AS1)is involved in the progression of multiple cancers,but its role in epithelial ovarian cancer(EOC)is ***,we investigated the expression levels of IDH1-AS1 in EOC cells and normal ovarian epithelial cells by quantitative real-time PCR(qPCR).We first evaluated the effects of IDH1-AS1 on the proliferation,migration,and invasion of EOC cells through cell counting kit-8,colony formation,EdU,transwell,wound-healing,and xenograft *** then explored the downstream targets of IDH1-AS1 and verified the results by a dual-luciferase reporter,qPCR,rescue experiments,and Western *** found that the expression levels of IDH1-AS1 were lower in EOC cells than in normal ovarian epithelial *** IDH1-AS1 expression of EOC patients from the Gene Expression Profiling Interactive Analysis database indicated a favorable prognosis,because IDH1-AS1 inhibited cell proliferation and xenograft tumor growth of ***1-AS1 sponged miR-518c-5p whose overexpression promoted EOC cell *** miR-518c-5p mimic also reversed the proliferation-inhibiting effect induced by IDH1-AS1 ***,we found that RNA binding motif protein 47(RBM47)was the downstream target of miR-518c-5p,that upregulation of RBM47 inhibited EOC cell proliferation,and that RBM47 overexpressing plasmid counteracted the proliferation-promoting effect caused by the IDH1-AS1 *** together,IDH1-AS1 may suppress EOC cell proliferation and tumor growth via the miR-518c-5p/RBM47 axis.

关键词： lncRNA IDH1-AS1 epithelial ovarian cancer miR-518c-5p RBM47

Advanced nano drug delivery systems for neuroprotection against ischemic stroke

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Chinese Chemical Letters 2024年第2期35卷 151-162页

作者： chenchen Xie Jun Liao Ning Zhang Yuhan Sun Yi Li Liyan Xiong Yingnan Zhang Xiaoyan liu Wei Su Heming Chen Ping Zeng Xiaoqing Zhang Ying Lu Tingfang Wang Chuan Zhang Shanghai Engineering Research Center of Organ Repair School of MedicineShanghai UniversityShanghai 200444China Department of Pharmaceutical Science School of PharmacyNaval Medical UniversityShanghai 200433China Department of pharmacy the International Peace Maternity and Child Health HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200030China School of Pharmacy Shanghai Jiao Tong UniversityShanghai 200040China

Ischemic stroke(IS)represents a significant threat to brain health due to its elevated mortality and disability *** efficacy of small-molecule neuroprotective agents has been impeded by challenges associated with traversing the blood-brain barrier(BBB)and limited ***,advanced nano drug delivery systems hold promise for overcoming these obstacles by facilitating efficient transportation across the BBB and maintaining optimal drug *** review aims to explore advanced neuroprotective nano drug delivery systems as a means of effectively administering neuroprotective agents to the brain using pharmaceutical approaches in the treatment of *** examining these systems,researchers and clinicians can gain valuable insights and innovative concepts,illuminating the potential of advanced neuroprotective nano drug delivery *** these advancements can drive the progress of pioneering and efficacious therapeutic interventions for IS.

关键词： Target Blood-brain barrier Ischemic stroke Nano drug delivery Neuroprotection

“交通”天人：商周时期巫文化演进的传播学考古研究

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国际新闻界 2019年第11期41卷 89-114页

作者：钱佳湧刘辰辰上海大学新闻传播学院

传播不止于现实世界中的信息传递和意义共享,同时也包含人们在现实世界与超越世界之间寻求沟通的努力。这种努力在中国古代体现在"巫"这一特殊职业群体"交通天人"的沟通活动中。初民社会中,这种天人之际的沟通活动更多是基于生存的现实... 详细信息

传播不止于现实世界中的信息传递和意义共享,同时也包含人们在现实世界与超越世界之间寻求沟通的努力。这种努力在中国古代体现在"巫"这一特殊职业群体"交通天人"的沟通活动中。初民社会中,这种天人之际的沟通活动更多是基于生存的现实需求而产生的对超自然神秘力量的崇拜和模仿。"绝地天通"之后,兼行巫职的"王"垄断了"交通天人"的权力,并通过将权力秩序视作宇宙运行秩序之现世映射的方式合理化了权力集中化的现实。随着"天人合一"思想的出现,个人文化道德品质抽象出来的价值系统开始取代超自然的、具有实体性的神秘力量,成为统治者在"交通天人"中意欲沟通的对象。由此,现世权力秩序的合法性途径也从寻求外在于人的神祗之赐福与授权转变为统治者本人在文化道德品质的超然地位。

关键词：传播考古巫文化神圣性

7075航空铝合金原位腐蚀-多轴疲劳行为分析

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中国机械工程 2019年第5期30卷 615-621页

作者：刘辰辰陈亚军李柯王川中国民航大学中欧航空工程师学院天津300300 航天精工股份有限公司天津300300

针对沿海地区飞机服役过程中的疲劳失效问题,利用自行开发的腐蚀装置对7075铝合金进行未腐蚀和3.5%NaCl盐雾原位腐蚀条件下,等效应力分别为200 MPa、250 MPa和300 MPa时的多轴疲劳试验。结合循环曲线和断口形貌对未腐蚀和原位腐蚀条件... 详细信息

针对沿海地区飞机服役过程中的疲劳失效问题,利用自行开发的腐蚀装置对7075铝合金进行未腐蚀和3.5%NaCl盐雾原位腐蚀条件下,等效应力分别为200 MPa、250 MPa和300 MPa时的多轴疲劳试验。结合循环曲线和断口形貌对未腐蚀和原位腐蚀条件下的多轴疲劳失效机理进行对比分析,并提出改进的Manson-Coffin-Basquin(MCB)准则进行寿命预测。结果表明,随着等效应力的增大,7075铝合金未腐蚀和原位腐蚀条件下多轴疲劳寿命均下降;等效应力相同时,相对于未腐蚀试样,原位腐蚀试样的多轴疲劳寿命显著缩短,轴向和扭向滞回线的面积均不同程度增大;200 MPa等效应力条件下,试样多轴疲劳寿命在未腐蚀条件下为99 675周次,原位腐蚀条件下下降至55 284周次;未腐蚀和原位腐蚀条件下,裂纹源均出现在外表面,原位腐蚀试样扩展区有盐粒出现;修正的MCB准则引入加载条件和环境因素,得到了良好的预测效果,寿命预测值均位于两倍分散带内。

关键词： 7075铝合金多轴疲劳原位腐蚀失效机理寿命预测