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Three-dimensional echocardiographic assessment of left ventricular volume in different heart diseases using a fully automated quantification software

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World Journal of Clinical Cases 2022年第13期10卷 4050-4063页

作者： chen-ke pan Bo-Wen Zhao Xuan-Xuan Zhang Mei pan Yan-Kai Mao Yuan Yang Department of Diagnostic Ultrasound and Echocardiography Sir Run Run Shaw HospitalZhejiang University College of MedicineHangzhou 310016Zhejiang ProvinceChina Department of Ultrasound The Fourth Affiliated Hospital of Zhejiang University College of MedicineYiwu 322200Zhejiang ProvinceChina

BACKGROUND HeartModel(HM)is a fully automated adaptive quantification software that can quickly quantify left heart volume and left ventricular *** study used HM to quantify the left ventricular end-diastolic(LVEDV)and end-systolic volumes(LVESV)of patients with dilated cardiomyopathy(DCM),coronary artery heart disease with segmental wall motion abnormality,and hypertrophic cardiomyopathy(HCM)to determine whether there were differences in the feasibility,accuracy,and repeatability of measuring the LVEDV,LVESV,LV ejection fraction(LVEF)and left atrial end-systolic volume(LAESV)and to compare these measurements with those obtained with traditional twodimensional(2D)and three-dimensional(3D)*** To evaluate the application value of HM in quantifying left heart chamber volume and LVEF in clinical *** A total of 150 subjects who underwent 2D and 3D echocardiography were divided into 4 groups:(1)42 patients with normal heart shape and function(control group,Group A);(2)35 patients with DCM(Group B);(3)41 patients with LV remodeling after acute myocardial infarction(Group C);and(4)32 patients with HCM(Group D).The LVEDV,LVESV,LVEF and LAESV obtained by HM with(HM-RE)and without regional endocardial border editing(HM-NE)were compared with those measured by traditional 2D/3D echocardiographic methods to assess the correlation,consistency,and repeatability of all ***(1)The parameters measured by HM were significantly different among the groups(P<0.05 for all).Compared with Groups A,C,and D,Group B had higher LVEDV and LVESV(P<0.05 for all)and lower LVEF(P<0.05 for all);(2)HM-NE overestimated LVEDV,LVESV,and LAESV with wide biases and underestimated LVEF with a small bias;contour adjustment reduced the biases and limits of agreement(bias:LVEDV,28.17 mL,LVESV,14.92 mL,LAESV,8.18 mL,LVEF,-0.04%).The correlations between HM-RE and advanced cardiac 3D quantification(3DQA)(r_(s)=0.91-0.95,P<0.05 for all)were higher than those between HM-NE(

关键词： HeartModel Three-dimensional echocardiography Left ventricular volume Left ventricular ejection function Left atrial volume

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Bedside ultrasound-guided water injection assists endoscopically treatment in esophageal perforation caused by foreign bodies: A case report

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1240-1246页

作者： Hua-Xing Wei Song-Yong Lv Bin Xia Kai Zhang chen-ke pan Department of Ultrasound The Fourth Affiliated Hospital of Zhejiang University College of MedicineYiwu 322200Zhejiang ProvinceChina Department of Ultrasound Jinyun County People’s HospitalLishui 321400Zhejiang ProvinceChina

BACKGROUND Fishbone migration from the esophagus to the neck is relatively uncommon in clinical *** complications secondary to esophageal perforation after ingestion of a fishbone have been described in the ***,a fishbone is detected and diagnosed by imaging examination and is usually removed by a neck *** SUMMARY Herein,we report a case of a 76-year-old patient with a fishbone in the neck that had migrated from the esophagus and that was in close proximity to the common carotid artery,and the patient experienced *** endoscopically-guided neck incision was made over the insertion point in the esophagus,but the surgery failed due to having a blurred image at the insertion site during the *** injection of normal saline laterally to the fishbone in the neck under ultrasound guidance,the purulent fluid outflowed to the piriform recess along the sinus *** endoscopic guidance,the position of the fish bone was precisely located along the direction of liquid outflow,the sinus tract was separated,and the fish bone was *** the best of our knowledge,this is the first case report describing bedside ultrasound-guided water injection positioning combined with endoscopy in the treatment of a cervical esophageal perforation with an *** In conclusion,the fishbone could be located by the water injection method under the guidance of ultrasound and could be accurately located along the outflow direction of the purulent fluid of the sinus by the endoscope and was removed by incising the *** method can be a nonoperative treatment option for foreign body-induced esophageal perforation.

关键词： Esophageal perforation Foreign body removal Fishbone Beside ultrasound-guided Endoscopy Case report

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Decreased expression of Neurensin-2 correlates with poor prognosis in hepatocellular carcinoma

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World Journal of Gastroenterology 2009年第38期15卷 4844-4848页

作者： Hai-Qing Ma Xiao-Ting Liang Jing-Jing Zhao Hui Wang Jian-Cong Sun Yi-Bing chen ke pan Jian-Chuan Xia key Laboratory of Oncology in Southern China and Departmentof Experimental Research Sun Yat-sen University Cancer CenterGuangzhou 510060 Guangdong Province China

AIM： To investigate the expression of Neurensin-2 （NRSN2） in hepatocellular carcinoma （HCC） and its prognostic values in predicting survival. METHODS： The expression and prognostic significance of NRSN2 in HCC was examined by performing immunohistochemical analysis using a total of 110 HCC clinical tissue samples, and Western blotting analysis to further confirm the result. RESULTS： Decreased NRSN2 expression was shown in 70.9% cases. Loss of NRSN2 expression in HCC was significantly related to tumor size （P = 0.006）. Larger tumor size was related to negative expression of NRSN2. Patients showing negative NRSN2 expression had a significantly shorter overall survival than those with positive expression （P = 0.008）. Multivariate Cox regression analysis indicated that NRSN2 expression level was an independent factor of survival （P = 0.013）. Western blotting analysis further confirmed decreased expression of NRSN2 in tumor tissues compared with non-tumorous tissues. CONCLUSION： Our study indicated that NRSIV2 could be a tumor suppressor gene for HCC and a candidate biomarker for long-term survival in HCC.

关键词： Neurensin-2 Hepatocellular carcinoma Expression Immunohistochemical analysis Prognosis

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Engineering atomic Rb-N configurations to tune radical pathways for highly selective photocatalytic H2O2 synthesis coupled with biomass valorization

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Journal of Energy Chemistry 2025年第1期100卷 215-225页

作者： Jiaye Li Shuang pan Yihuang chen Qiong Liu College of Chemistry and Materials Engineering Wenzhou University Guangdong Provincial key Laboratory of Chemical Measurement and Emergency Test Technology (China) Institute of Analysis Guangdong Academy of Sciences (China National Analytical CenterGuangzhou)

Photocatalytic oxygen reduction for hydrogen peroxide （H2O2） synthesis presents a green and costeffective production ***,achieving highly selective H2O2synthesis remains challenging,necessitating precise control over free radical reaction pathways and minimizing undesirable oxidative ***,we report for the visible light-driven simultaneous co-photocatalytic reduction of O2to H2O2and oxidation of biomass using the atomic rubidium-nitride modified carbon nitride（CNRb）.The optimized CNRb catalyst demonstrates a record photoreduction rate of 8.01 mM h-1for H2O2generation and photooxidation rate of 3.75 mM h-1for furfuryl alcohol to furoic acid,achieving a remarkable solar-to-chemical conversion （SCC） efficiency of up to 2.27%.Experimental characterizations and DFT calculation disclosed that the introducing atomic Rb–N configurations allows for the high-selective generation of superoxide radicals while suppressing hydroxyl free radical *** is because the Rb–N serves as the new alternative site to perceive a stronger connection position for O2adsorption and reinforce the capability to extract protons,thereby triggering a high selective redox product *** study holds great potential in precisely regulating reactive radical processes at the atomic level,thereby paving the way for efficient synthesis of H2O2coupled with biomass valorization.

关键词： Atomic economy Radical pathway regulation Rubidium atom coordination Biomass valorization

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Co-production of hydrogen, oxygen, and electricity via an integrated solar-driven system with decoupled water electrolyzer and Na-Zn ion battery

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Journal of Energy Chemistry 2025年第1期100卷 621-627页

作者： Fei Lv Longjie Liu Jiazhe Wu Pengfei Wang Lixia pan Dengwei Jing Yubin chen International Research Center for Renewable Energy State Key Laboratory of Multiphase Flow in Power Engineering Xi'an Jiaotong University

Combining water electrolysis and rechargeable battery technologies into a single system holds great promise for the co-production of hydrogen （H2） and ***,the design and development of such systems is still in its ***,an integrated hydrogen-oxygen （O2）-electricity co-production system featuring a bipolar membrane-assisted decoupled electrolyzer and a Na-Zn ion battery was established with sodium nickelhexacyanoferrate （NaNiHCF） and Zn2+/Zn as dual redox *** decoupled electrolyzer enables to produce H2and O2in different time and space with almost 100%Faradaic efficiency at 100 mA ***,the charged NaNiHCF and Zn electrodes after the electrolysis processes formed a Na-Zn ion battery,which can generate electricity with an average cell voltage of 1.75 V at 10 m A *** connecting Si photovoltaics with the modular electrochemical device,a well-matched solar driven system was built to convert the intermittent solar energy into hydrogen and electric energy with a solar to hydrogen-electricity efficiency of 16.7%,demonstrating the flexible storage and conversion of renewables.

关键词： Hydrogen Electricity Decoupled water electrolyzer Na-Zn ion battery Solar energy

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THE CRYSTAL STRUCTURE OF PSEUDOLARIC ACID D

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结构化学 1986年第3期 190-192页

作者： Wu Jianhua Wang Boyi Zheng PeijuCenter of Analysis and Measurament, Fudan UniversityLi Zhulian chen ke pan DejiSchool of Pharmceutical Science, Shanghai Medical InstituteXu GuangyiShanghai Institute of Pharmaceutical Industry

Mr=318.46, orthorhombic, P212121, a=6.921(2), b=10.175(2), c= 25.036(5) A, Z=4, Dc=1.200 ***-3, V=1763.0 A3, final R=0.057 for 1451 observed reflections. The rings A and B take chair conformations, so is the ring C ap... 详细信息

关键词：七八 THE CRYSTAL STRUCTURE OF PSEUDOLARIC ACID D ACID

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聚丙烯酰胺稀溶液的分子模拟

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物理化学学报 2010年第11期26卷 2907-2914页

作者：刘艳艳陈攀科罗健辉周歌江波四川大学化学学院绿色化学与技术教育部重点实验室成都610064 中国石油勘探开发研究院北京100083

聚丙烯酰胺(PAM)是一类重要的线性水溶性聚合物,具有"百业助剂"之称,因此对其溶液性质的研究意义重大.在溶液质量浓度约为1g·mL-1的基础上,分别构建了含有不同水分子数的溶液模型.采用分子动力学(MD)方法模拟分析了不同温度下非离子型... 详细信息

聚丙烯酰胺(PAM)是一类重要的线性水溶性聚合物,具有"百业助剂"之称,因此对其溶液性质的研究意义重大.在溶液质量浓度约为1g·mL-1的基础上,分别构建了含有不同水分子数的溶液模型.采用分子动力学(MD)方法模拟分析了不同温度下非离子型的聚丙烯酰胺(PAM-H)和阴离子型的聚丙烯酰胺(HPAM)在纯水溶液及含不同质量分数NaCl的水溶液中的回旋半径(Rg).结果发现,不同温度下PAM-H和HPAM的抗盐性能的模拟结果与实验数据基本吻合,水分子数不同的溶液模型所得模拟结果趋势没有明显变化,为了提高模拟效率,选取含有2000个水分子的溶液模型分析HPAM链中氧负离子及氧原子的径向分布函数,从微观结构模拟说明了HPAM水溶液粘度随NaCl质量分数增加而减小,且HPAM比PAM-H具有较好的增粘效果及较差的抗盐性能的原因.

关键词：分子动力学聚丙烯酰胺溶液性质回旋半径径向分布函数

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Construction of 3D porous Cu_(1.81)S/nitrogen-doped carbon frameworks for ultrafast and long-cycle life sodium-ion storage

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 191-200页

作者： chen chen Hongyu Xue Qilin Hu Mengfan Wang pan Shang Ziyan Liu Tao Peng Deyang Zhang Yongsong Luo key Laboratory of Microelectronics and Energy of Henan Province Henan Joint International Research Laboratory of New Energy Storage TechnologyCollege of Physics and Electronic EngineeringXinyang Normal UniversityXinyang 464000China School of Physics and Electronic Engineering Nanyang Normal UniversityNanyang 473061China

Transition metal sulfides have great potential as anode mterials for sodium-ion batteries(SIBs)due to their high theoretical specific ***,the inferior intrinsic conductivity and large volume variation during sodiation-desodiation processes seriously affect its high-rate and long-cyde performance,unbeneficial for the application as fast-charging and long-cycling SIBs ***,the three-dimensional porous Cu_(1.81)S/nitrogen-doped carbon frameworks(Cu_(1.81)S/NC)are synthesized by the simple and facile sol-gel and annealing processes,which can accommodate the volumetric expansion of Cu_(1.81)S nanoparticles and accelerate the transmission of ions and electrons during Na^(+)insertion/extraction processes,exhibiting the excellent rate capability(250.6 mA·g^(-1)at 20.0 A·g^(-1))and outstanding cycling stability(70% capacity retention for 6000 cycles at 10.0 A·g^(-1))for ***,the Na-ion full cells coupled with Na_(3)V_(2)(PO_(4))_(3)/C cathode also demonstrate the satisfactory reversible specific capacity of 330.5 mAh·g^(-1)at 5.0 A·g^(-1)and long-cycle performance with the 86.9% capacity retention at 2.0 A·g^(-1)after 750 *** work proposes a promising way for the conversionbased metal sulfides for the applications as fast-charging sodium-ion battery anode.

关键词： copper sulfide nanoparticles porous carbon framework fast charging long-cycle performance sodium-ion full batteries

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腺病毒介导hRAMP1基因转染血管平滑肌细胞的增殖和凋亡

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中国组织工程研究与临床康复 2011年第46期15卷 8598-8602页

作者：龙仙萍赵然尊石蓓崔璨盛瑾陈攀科遵义医学院第一附属医院心血管内科贵州省遵义市563003

背景:外源性受体活性修饰蛋白1基因转染可能对血管平滑肌细胞增殖调控具有重要的作用。目的:探讨腺病毒载体介导人受体活性修饰蛋白1基因对体外培养的兔血管平滑肌细胞增殖和凋亡的影响。方法:分离培养获得兔主动脉血管平滑肌细胞,分别... 详细信息

背景:外源性受体活性修饰蛋白1基因转染可能对血管平滑肌细胞增殖调控具有重要的作用。目的:探讨腺病毒载体介导人受体活性修饰蛋白1基因对体外培养的兔血管平滑肌细胞增殖和凋亡的影响。方法:分离培养获得兔主动脉血管平滑肌细胞,分别以携带人受体活性修饰蛋白1基因的腺病毒和空腺病毒转染后,分成人受体活性修饰蛋白1组、空病毒组和对照组。结果与结论:腺病毒转染细胞后随时间延长,报告基因绿色荧光蛋白表达逐渐增加,72h表达最强,感染率达80%,96h时仍有绿色荧光蛋白表达。人受体活性修饰蛋白1组的受体活性修饰蛋白1蛋白表达增加,血管平滑肌细胞凋亡率增加,细胞增殖明显抑制,与空病毒组和对照组比较差异有显著性意义(P<0.05)。提示人受体活性修饰蛋白1基因感染血管平滑肌细胞后明显抑制血管平滑肌细胞增殖,促进细胞凋亡。

关键词：受体活性修饰蛋白1 降钙素基因相关肽血管平滑肌细胞增殖凋亡

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Enhanced electrochemical CO_(2)reduction coupled with urea oxidation using bifunctional atomically dispersed CuNi catalysts

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Nano Research 2025年第1期18卷 208-216页

作者： Wenjie Wu Haoyang Zhou Ying Liu Yifei pan Qingqing chen Yu Zhang Junjie Mao Wenjie Ma Ping Yu Beijing National Laboratory for Molecular Sciences Key Laboratory of Analytical Chemistry for Living BiosystemsInstitute of ChemistryChinese Academy of Sciences(CAS)Beijing 100190China College of Chemistry and Materials Science Anhui Normal UniversityWuhu 241002China University of Chinese Academy of Sciences Beijing 100049China

The electrochemical conversion of carbon dioxide(CO_(2))into chemical fuels represents a promising approach for addressing global carbon balance ***,this process is hindered by the kinetic limitations of anodic reactions,usually the oxygen evolution reaction,resulting in less efficient production of high value-added ***,we report an integrated electrocatalytic system that couples CO_(2)reduction reaction(CO_(2)RR)with urea oxidation reaction(UOR)using a bifunctional electrocatalyst with atomically dispersed dual-metal CuNi sites anchored on bamboo-like nitrogen-doped carbon nanotubes(CuNi-CNT),which were synthesized through a one-step pyrolysis *** bifunctional CuNi-CNT catalyst exhibits a near 100%CO Faraday efficiency for CO_(2)RR over a wide potential range and outstanding UOR performance with a negatively shifted potential of 210 mV at 10 mA·cm^(-2).In addition,we assemble a two-electrode electrolyzer using bifunctional CuNi-CNT-modified carbon fiber paper electrodes as both cathode and anode,capable of operating at a remarkably low cell voltage of 1.81 V at 10 mA·cm-2,significantly lower than conventional *** study provides a novel avenue to achieving an efficient carbon cycle with reduced electric power consumption.

关键词： electrochemical conversion bimetallic site catalyst bifunctional electrocatalyst carbon dioxide reduction urea oxidation

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