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Signal Transduction and Targeted Therapy 2021年第4期6卷 1113-1115页

作者： Chang-Long He Lu-Yi Huang Kai Wang chen-jian gu Jie Hu gui-Ji Zhang Wei Xu You-Hua Xie Ni Tang Ai-Long Huang Key Laboratory of Molecular Biology for Infectious Diseases(Ministry of Education) Institute for Viral HepatitisDepartment of Infectious DiseasesThe Second Affiliated HospitalChongqing Medical UniversityChongqingChina Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS) Department of Medical Microbiology and ParasitologySchool of Basic Medical SciencesShanghai Medical CollegeFudan UniversityShanghaiChina Children's Hospital Fudan UniversityShanghaiChina

Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a major public health *** spike(S)protein mutation D614G became dominant in SARS-CoV-2 during a global pandemic,which displayed increased infectivity.1 Entry of a virus into host cells is one of the most critical steps in the viral life *** blockade of the entry process is a promising therapeutic option for COVID-19,research attention has been focused on the discovery of viral entry *** SARS-CoV-2 entry inhibitor development is very attractive,no candidates have progressed into clinical trials yet.

关键词： acute respiratory attractive

AI-Enhanced Secure Data Aggregation for Smart Grids with Privacy Preservation

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Computers, Materials & Continua 2025年第1期82卷 799-816页

作者： Congcong Wang chen Wang Wenying Zheng Wei gu School of Software Nanjing University of Information Science and TechnologyNanjing210044China School of Information Science and Engineering Zhejiang Sci-Tech UniversityHangzhou310018China State Key Laboratory of Public Big Data Guizhou UniversityGuiyang550025China School of Computer Science and Technology(School of Artificial Intelligence) Zhejiang Sci-Tech UniversityHangzhou310018China School of Computer Science(School of Cyber Science and Engineering) Nanjing University of Information Science and TechnologyNanjing210044China

As smart grid technology rapidly advances,the vast amount of user data collected by smart meter presents significant challenges in data security and privacy *** research emphasizes data security and user privacy concerns within smart ***,existing methods struggle with efficiency and security when processing large-scale *** efficient data processing with stringent privacy protection during data aggregation in smart grids remains an urgent *** paper proposes an AI-based multi-type data aggregation method designed to enhance aggregation efficiency and security by standardizing and normalizing various data *** approach optimizes data preprocessing,integrates Long Short-Term Memory(LSTM)networks for handling time-series data,and employs homomorphic encryption to safeguard user *** also explores the application of Boneh Lynn Shacham(BLS)signatures for user *** proposed scheme’s efficiency,security,and privacy protection capabilities are validated through rigorous security proofs and experimental analysis.

关键词： Smart grid data security privacy protection artificial intelligence data aggregation

Mutual-structure weighted guided image filtering for depth map restoration

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Optoelectronics Letters 2025年第1期21卷 51-56页

作者： LIU Zijian SONG jian chen Quanmin XU jiangtao Tianjin Key Laboratory of Imaging and Sensing Microelectronic Technology School of Microelectronics Tianjin University Spikesee Technology Co. Ltd.

Although guided image filtering(GIF) is known for preserving edges and fast computation, it may produce inaccurate outputs in depth map restoration. In this paper, a novel confidence-weighted GIF called mutual-structure weighted GIF(MSWGIF) is proposed, which replaces the mean filtering strategy in GIF during handling overlapping windows. The confidence value is composed of a depth term and a mutual-structure term, where the depth term is utilized to protect the edges of the output, and the mutual-structure term helps to select accurate windows during the structure characteristics of the guidance image are transferred to the output. Experimental results show that MSWGIF reduces the root mean square error(RMSE) by an average of 12.37%, and the average growth rate of correlation(CORR) is 0.07% on average. Additionally, the average growth rate of structure similarity index measure(SSIM) is 0.34%.

关键词： Wiener filtering

Preparation and Performance of Ternary Early Strength Agent and Quercetin Composite Cement Sealing Material

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 130-140页

作者： LIU jian chen Meiting JI Xiaoli XU Chao WANG Chunmei Department of Safety Science and Engineering Anhui University of Science and TechnologyHuainan 232001China Key Laboratory of Mine Safety and High Efficient Mining Jointly Built by Province and Education Ministry Anhui University of Science and TechnologyHuainan 232001China Department of Chemical Engineering and Explosives Anhui University of Science and TechnologyHuainan 232001China

A ternary early-strengthening agent consisting of calcium formate+triethanolamine+lithium sulfate was compounded with quercetin to shorten the setting time of cementitious materials while ensuring their early *** optimum ratio of the three early-strengthening agents was determined as 0.5%calcium formate+0.04%triethanolamine+0.4%lithium sulfate by response surface *** effects of the ternary early-strengthening agent composed of calcium formate+triethanolamine(TEA)+lithium sulfate on cementitious pore sealing materials under the synergistic effect of quercetin were studied by means of the performance tests of compressive strength,fluidity,and setting time,and the microstructural characterizations of X-ray powder diffractometer(XRD),thermogravimetry(TG-DSC)and scanning electron microscopy(SEM).The study shows that the synergistic effect of ternary early-strengthening agent and quercetin forms a multi-performance composite admixture for cementitious *** best performance was obtained with the compounding scheme of 0.5%calcium formate+0.04%triethanolamine+0.4%lithium sulfate ternary early-strengthening agent and 0.05%*** compressive strength of 1,3,7,and 28 d are 94.8%,39.8%,42%,and 28%higher than those of the blank group,*** initial time and final setting time are 41 and 57 minutes,*** to the microscopic analysis,the network and fibrous C-S-H gels generated by ternary early-strengthening agents are attached to the surface promoted by quercetin,which forms skeleton support while thickening and solidifying the cement slurry,which enhances the early compressive strength of the cement-based materials.

关键词： sealing material ternary early-strengthening agent quercetin synergetic effect response surface methodology

固体CD光谱研究及其应用于手性席夫碱M(II)配合物

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物理化学学报 2006年第6期22卷 666-671页

作者：章慧陈渊川王芳邱晓明李丽陈坚固厦门大学化学化工学院

结合课题组近期的相关研究,对固体CD光谱在手性配合物研究中的应用,特别是手性样品固体CD光谱的测试方法进行了概述,通过对四对手性席夫碱M(II)(M=Ni、Cu)配合物的固体和溶液CD光谱进行比较研究,发现配合物的手性构型在固液相中保持一致... 详细信息

结合课题组近期的相关研究,对固体CD光谱在手性配合物研究中的应用,特别是手性样品固体CD光谱的测试方法进行了概述,通过对四对手性席夫碱M(II)(M=Ni、Cu)配合物的固体和溶液CD光谱进行比较研究,发现配合物的手性构型在固液相中保持一致,但其固液CD光谱之间存在不同程度的差异,可能是由于相应配合物在固体和溶液相中的四面体扭曲或构象的微妙不同所致.

关键词：固体圆二色(CD)光谱测试方法手性席夫碱M(Ⅱ)配合物

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Observation of topological charge transformations in acoustic vortex using passive periodic systems

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 140-147页

作者： Di-Chao chen Xie Liu Changqing Xu Da-jian Wu Ying cheng Xiao-Jun Liu School of Physics and Technology Nanjing Normal University Key Laboratory of Modern Acoustics School of Physics Nanjing University

Vortex transmutation utilizes a periodic system, which not only enables the alteration of the topological charge(TC) of unstable input vortices but also facilitates their transformation into stable structures. This approach is crucial for investigating the characteristics of vortices in various wave systems. Here, we achieve acoustic vortex TC transmutation by employing a welldesigned dual-structured plate external system(DPES). The interactions between the acoustic vortex and the finite-order discrete rotational symmetry lead to the transformation of its topological charge when complete rotational symmetry is broken to Nthorder discrete symmetry. Our results experimentally demonstrate the acoustic vortex TC transmutation based on passive artificial structures, enabling numerous applications in particle manipulation and information multiplexing as well as advancing our understanding and control over free-space acoustic vortices.

关键词： acoustic vortex topological charge transformation artificial structure

Two paths, one goal: mechanism of calcium homeostasis to balance plant growth and immunity

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Science China Life Sciences 2025年第1期 306-308页

作者： Aziz Ul Ikram Yanping Jing Huan chen jian chen International Genome Center Jiangsu University Joint Center for Single Cell Biology School of Agriculture and BiologyShanghai Jiao Tong University

Calcium(Ca2+) is an essential nutrient and a cellular signal in plants. The level of free Ca2+in the apoplast is ～10,000-fold higher than that in the cytoplasm at the resting state. This large Ca2+level gradient across the membrane between the interior and exterior can cause Ca2+overload and toxicity. Plants have evolved mechanisms to export Ca2+out of the cytoplasm or store it in intracellular organelles, such as endoplasmic reticulum（ER）, mitochondria, and vacuole.

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Preparation of Modified Composite Nanofiltration Membrane Synergistically Using Carboxylic Multi- walled Carbon Nanotube and β-cyclodextrin

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 232-239页

作者： LIU Peng MAO Junpeng FANG Yanfeng YU Yunwu chen Changxiu TANG Ning WAN Ye gu Yaxin LIU Yunxue WANG Lihua School of Materials Science and Engineering Shenyang Jianzhu UniversityShenyang 110168China

A new modified blend ultrafiltration(UF)membrane with good hydrophilicity,high porosity and excellent anti-fouling performance was developed by using carboxylic multi-walled carbon nanotube(CMWCNT)as casting solution ***,a composite nanofiltration(NF)membrane with large water flux and good retention rate was fabricated by using the PVDF/CMWCNT blend UF membrane as the substrate,and polyvinyl alcohol(PVA),β-cyclodextrin(β-CD)and polyethylenimine(PEI)as the coating *** results show that with the appropriate addition of CMWCNT in the casting solution,the surface roughness,porosity and recovery rate of the PVDF/CMWCNT blend UF membrane is obviously *** water flux of blend UF membrane is significantly improved when the CMWCNT content increases from 0 wt%to 0.2 wt%.The water flux of blend UF membrane with 0.2 wt%CMWCNT is 162.7 L/(m^(2)·h),which is 44.3%higher than that of the pure PVDF ***β-CD content is 0.8 wt%,the retention rate of Congo red by PVDF/CMWCNT/β-CD composite NF membrane reaches 98.7%,which is 28.3%higher than that of single PVA/PEI modified *** research will provide a new idea and simple method for developing novel high-performance composite NF membranes.

关键词： CMWCNT cyclodextrin nanofiltration membrane

Rapid and scalable preparation of highly quaternized polymer networks to achieve efficient simultaneous adsorption of iodide and pertechnetate

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Science China Chemistry 2025年第01期 337-349页

作者： Meiyun Xu Song gu Fulong chen Zhe Zhao Peng Liu Daoben Hua State Key Laboratory of Radiation Medicine and Protection School of Radiological and Interdisciplinary Sciences (RAD-X) Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions Soochow University

The efficient separation of fission products,such as TcO4-and I-,holds strategic significance for the management of radioactive wastes and environmental *** this study,we propose an ultrafast strategy for scalable preparation of a highly quaternized organic network to facilitate efficient and synchronous separation of iodide and *** network can be prepared within a few minutes at room temperature,using polyethylenimine and 1,2,4,5-tetrakis（bromomethyl）benzene as building *** chlorine replacement,the network,abundantly decorated with quaternary ammonium groups （Cl@QPN）,exhibits an ultrahigh positive charge density of 7.6 mmol/*** enables the rapid and efficient enrichment of target anions through strong electrostatic Coulomb *** a result,Cl@QPN exhibits significantly higher adsorption rate constants of 0.830 g/（mg min） for ReO4-（a nonradioactive surrogate of TcO4-） and 0.677 g/（mg min） for I-compared to other ***,it possesses high adsorption capacities,reaching 1,681 mg/g for ReO4-and 917.4 mg/g for I-.Cl@QPN also demonstrates good selectivity towards target ions and shows efficient adsorption for99TcO4-.Additionally,Cl@QPN exhibits high dynamic processing capacities,handling up to 3,100 and 7,400 kg of simulated streams per kilogram of material for I-and ReO4-,respectively.

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Recent progress in the applications of presynaptic dopaminergic positron emission tomography imaging in parkinsonism

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Neural Regeneration Research 2025年第1期20卷 93-106页

作者： Yujie Yang Xinyi Li Jiaying Lu Jingjie Ge Mingjia chen Ruixin Yao Mei Tian jian Wang Fengtao Liu Chuantao Zuo Key Laboratory of Arrhythmias Ministry of EducationDepartment of Medical GeneticsShanghai East HospitalSchool of MedicineTongji UniversityShanghaiChina Department of Neurology National Research Center for Aging and MedicineNational Center for Neurological Disordersand State Key Laboratory of Medical NeurobiologyHuashan HospitalFudan UniversityShanghaiChina Department of Nuclear Medicine&PET Center National Center for Neurological Disordersand National Clinical Research Center for Aging and MedicineHuashan HospitalFudan UniversityShanghaiChina International Human Phenome Institutes(Shanghai) ShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Nowadays,presynaptic dopaminergic positron emission tomography,which assesses deficiencies in dopamine synthesis,storage,and transport,is widely utilized for early diagnosis and differential diagnosis of *** review provides a comprehensive summary of the latest developments in the application of presynaptic dopaminergic positron emission tomography imaging in disorders that manifest *** conducted a thorough literature search using reputable databases such as PubMed and Web of *** criteria involved identifying peer-reviewed articles published within the last 5 years,with emphasis on their relevance to clinical *** findings from these studies highlight that presynaptic dopaminergic positron emission tomography has demonstrated potential not only in diagnosing and differentiating various Parkinsonian conditions but also in assessing disease severity and predicting ***,when employed in conjunction with other imaging modalities and advanced analytical methods,presynaptic dopaminergic positron emission tomography has been validated as a reliable in vivo *** validation extends to screening and exploring potential neuropathological mechanisms associated with dopaminergic *** summary,the insights gained from interpreting these studies are crucial for enhancing the effectiveness of preclinical investigations and clinical trials,ultimately advancing toward the goals of neuroregeneration in parkinsonian disorders.

关键词： aromatic amino acid decarboxylase brain imaging dopamine transporter Parkinson’s disease parkinsonism positron emission tomography presynaptic dopaminergic function vesicle monoamine transporter type 2

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