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The Magnaporthe oryzae effector Avr-PikD suppresses rice immunity by inhibiting an LSD1-like transcriptional activator

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The Crop Journal 2024年第2期12卷 482-492页

作者： Jiayuan Guo Yiling wu Jianqiang Huang Kaihui yu Meilian chen Yijuan Han Zhenhui Zhong Guodong Lu Yonghe Hong Zonghua Wang Xiaofeng chen Fujian Universities Engineering Research Center of Marine Biology and Drugs Fuzhou Institute of OceanographyCollege of Geography and OceanographyMinjiang UniversityFuzhou 350108FujianChina Rice Research Institute Fujian Academy of Agricultural SciencesFuzhou 350018FujianChina Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops Minjiang UniversityFuzhou 350108FujianChina State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops College of Plant ProtectionFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina

Avirulence effectors(Avrs),encoded by plant pathogens,can be recognized by plants harboring the corresponding resistance proteins,thereby initiating effector-triggered immunity(ETI).In susceptible plants,however,Avrs can function as effectors,facilitating infection via effector-triggered susceptibility(ETS).Mechanisms of Avr-mediated ETS remain largely *** we report that the Magnaporthe oryzae effector Avr-PikD enters rice cells via the canonical cytoplasmic secretion pathway and suppresses rice basal ***-PikD interacts with an LSD1-like transcriptional activator AKIP30 of rice,and AKIP30 is also a positive regulator of rice immunity,whereas Avr-PikD impedes its nuclear localization and suppresses its transcriptional *** summary,*** delivers Avr-PikD into rice cells to facilitate ETS by inhibiting AKIP30-mediated transcriptional regulation of immune response against ***.

关键词： Magnaporthe oryzae Avirulence effector Avr-PikD Effector-triggered susceptibility Rice immunity Transcriptional activator

High-Performance All-Printed Flexible Micro-Supercapacitors with Hierarchical Encapsulation

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Energy & Environmental Materials 2024年第4期7卷 262-268页

作者： yuhang yuan Wei yuan Yaopeng wu Xuyang wu Xiaoqing Zhang Simin Jiang Bote Zhao yu chen chenghao Yang Liangxin Ding Zhenghua Tang Yingxi Xie Yong Tang School of Mechanical & Automotive Engineering South China University of Technology School of Environment and Energy South China University of Technology School of Chemistry and Chemical Engineering South China University of Technology

Printed micro-supercapacitors (MSCs) have shown broad prospect in flexible and wearable *** of previous studies focused on printing the electrochemically active materials paying less attention to other key components like current collectors and *** study presents an allprinting strategy to fabricate in-plane flexible and substrate-free MSCs with hierarchical encapsulation.

关键词： all-printing flexible hierarchical encapsulation micro-supercapacitors substrate-free

Generic Existence of Infinitely Many Non-contractible Closed Geodesics on Compact Space Forms

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Acta Mathematica Sinica,English Series 2024年第7期40卷 1674-1684页

作者： Hui Liu yu chen Wang School of Mathematics and Statistics Wuhan UniversityWuhan430072P.R.China School of Mathematics Tianjin Normal UniversityTianjin300384P.R.China

Let M=S^(n)/Γand h be a nontrivial element of finite order p inπ_(1)(Μ),where the integers n,p≥2,Γis a finite abelian group which acts freely and isometrically on the n-sphere and therefore M is diffeomorphic to a compact space *** this paper,we prove that there are infinitely many non-contractible closed geodesics of class[h]on the compact space form with C^(r)-generic Finsler metrics,where 4≤r≤∞.The conclusion also holds for Cr-generic Riemannian metrics for 2≤r≤∞.The proof is based on the resonance identity of non-contractible closed geodesics on compact space forms.

关键词： Compact space forms non-contractible closed geodesics generic Finsler metrics resonance identity

Safety-Critical Trajectory Tracking for Mobile Robots With Guaranteed Performance

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IEEE/CAA Journal of Automatica Sinica 2024年第9期11卷 2033-2035页

作者： Wentao wu Di wu Yibo Zhang Shukang chen Weidong Zhang Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China Department of Information and Communication Engineering Hainan UniversityHaikou 570288China

Dear Editor,This letter considers a collision-free trajectory tracking problem for performance-guaranteed mobile robots(MRs)subject to *** propose a safety-critical performance-guaranteed trajectory tracking method based on control barrier functions(CBFs).First,an auxiliary system is established to generate the non-negative signals for inflexible bounds such that the performance constraints are not violated when avoiding obstacles.

关键词： constraints bounds collision

Boosting hydrogen production of ammonia decomposition via the construction of metal-oxide interfaces

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Impact of open hepatectomy on postoperative bile leakage in patients with biliary tract cancer

结构化学 2024年第2期43卷 49-59页

作者： Jiangping chen Hongju Ren Kai wu Huihuang Fang Chongqi chen Li Lin yu Luo Lilong Jiang National Engineering Research Center for Chemical Fertilizer Catalyst(NERC-CFC) School of Chemical EngineeringFuzhou UniversityFuzhou350002China National Engineering Research Center for Chemical Fertilizer Catalyst(NERC-CFC) School of Chemical EngineeringFuzhou UniversityFuzhou350002China Qingyuan Innovation Laboratory QuanzhouFujian362801China

The ammonia decomposition for the production of carbon-free hydrogen has triggered great attention yet still remains challenging due to its sluggish kinetics,posting the importance of precise design of efficient catalysts for ammonia decomposition under low *** the metal-support interaction and interface is one of the most important strategies for promoting *** this work,by coating ceria onto the Ni nanoparticles(NPs),we discover that the Ni-CeO2 interfaces create an exceptional effect to enhance the catalytic decomposition of ammonia by over 10 folds,compared with the pristine *** kinetic analysis demonstrates that the recombinative N2 desorption is the rate-determining step(RDS)and the Ni-CeO2 interface greatly increases the *** on these understandings,a strategy to fabricate the Ni/CeO2 catalyst with abundant Ni-Ce-O in-terfaces via one-pot sol-gel method was employed(hereafter denoted to s-Ni/CeC2).The s-Ni/CeO2 catalyst shows a high activity for ammonia decomposition,achieving a H2 formation rate of 10.5 mmol gcat1 min-1 at 550 ℃.Combined with a series of characterizations,the relationship between the catalyst structure and the performance was investigated for further understanding the effect of metal-oxide interfaces.

关键词： Metal-support interaction Ammonia decomposition Nickel Cerium oxide Metal-oxide interfaces

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 67-75页

作者： Gang wu Wen-Ying Li yu-Xing Gong Feng Lin chen Sun General Surgery Department The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150000Heilongjiang ProvinceChina

BACKGROUND Bile leakage is a common and serious complication of open hepatectomy for the treatment of biliary tract *** To evaluate the incidence,risk factors,and management of bile leakage after open hepatectomy in patients with biliary tract *** We retrospectively analyzed 120 patients who underwent open hepatectomy for biliary tract cancer from February 2018 to February *** leak was defined as bile drainage from the surgical site or drain or the presence of a biloma on *** incidence,severity,timing,location,and treatment of the bile leaks were *** risk factors for bile leakage were analyzed using univariate and multivariate logistic regression *** The incidence of bile leak was 16.7%(20/120),and most cases were grade A(75%,15/20)according to the International Study Group of Liver Surgery *** median time of onset was 5 d(range,1-14 d),and the median duration was 7 d(range,2-28 d).The most common location of bile leakage was the cut surface of the liver(70%,14/20),followed by the anastomosis site(25%,5/20)and the cystic duct stump(5%,1/20).Most bile leaks were treated conservatively with drainage,antibiotics,and nutritional support(85%,17/20),whereas some required endoscopic retrograde cholangiopancreatography with stenting(10%,2/20)or percutaneous transhepatic cholangiography with drainage(5%,1/20).Risk factors for bile leakage include male sex,hepatocellular carcinoma,major hepatectomy,blood loss,and blood *** Bile leakage is a frequent complication of open hepatectomy for biliary tract ***,most cases are mild and can be conservatively *** sex,hepatocellular carcinoma,major hepatectomy,blood loss,and blood transfusion were associated with an increased risk of bile leak.

关键词： Open hepatectomy Bile leak Biliary tract cancer Risk factors Management Complication

Small nucleolar RNA and its potential role in the oncogenesis and development of colorectal cancer

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World Journal of Gastroenterology 2024年第2期30卷 115-127页

作者： Yang-Zheng Lan Zheng wu Wen-Jia chen Ze-Xuan Fang Xin-Ning yu Hua-Tao wu Jing Liu The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery The First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

Small nucleolar RNAs(snoRNAs)represent a class of non-coding RNAs that play pivotal roles in post-transcriptional RNA processing and modification,thereby contributing significantly to the maintenance of cellular functions related to protein *** have been discovered to possess the ability to influence cell fate and alter disease progression,holding immense potential in controlling human *** is suggested that the dysregulation of snoRNAs in cancer exhibits differential expression across various cancer types,stages,metastasis,treatment response and/or prognosis in *** the other hand,colorectal cancer(CRC),a prevalent malignancy of the digestive system,is characterized by high incidence and mortality rates,ranking as the third most common cancer *** research indicates that snoRNA dysregulation is associated with CRC,as snoRNA expression significantly differs between normal and cancerous ***,assessing snoRNA expression level and function holds promise for the prognosis and diagnosis of ***,current comprehension of the potential roles of snoRNAs in CRC remains *** review offers a comprehensive survey of the aberrant regulation of snoRNAs in CRC,providing valuable insights into the discovery of novel biomarkers,therapeutic targets,and potential tools for the diagnosis and treatment of CRC and furnishing critical cues for advancing research into CRC and the judicious selection of therapeutic targets.

关键词： Small nucleolar RNAs Colorectal cancer Dysregulation Biomarker

A nanoplatform with oxygen self-supplying and heat-sensitizing capabilities enhances the efficacy of photodynamic therapy in eradicating multidrug-resistant biofilms

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Journal of Materials Science & Technology 2024年第2期169卷 209-219页

作者： Haixin Zhang Yi Zou Kunyan Lu Yan wu yuancheng Lin Jingjing cheng Chunxia Liu Hong chen Yanxia Zhang Qian yu State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials College of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China Department of Cardiovascular Surgery of the First Affiliated Hospital and Institute for Cardiovascular Science Suzhou Medical College of Soochow UniversitySoochow UniversitySuzhou 215007China

Bacterial biofilms,especially those caused by multidrug-resistant bacteria,have emerged as one of the greatest dangers to global public *** acceleration of antimicrobial resistance to conventional an-tibiotics and the severe lack of new drugs necessitates the development of novel agents for biofilm *** therapy(PDT)is a promising non-antibiotic method for treating bacterial ***,its application in biofilm eradication is hampered by the hypoxic microenvironment of biofilms and the physical protection of extracellular polymeric *** this study,we develop a composite nanoplatform with oxygen(O_(2))self-supplying and heat-sensitizing capabilities to improve the PDT efficacy against ***_(2)/ICG@PDA nanoparticles(CIP NPs)are fabricated by combining calcium peroxide(CaO_(2))with the photosensitizer indocyanine green(ICG)via electrostatic interactions,followed by coating with polydopamine(PDA).The CIP NPs can gradually generate O_(2)in response to the acidic microenvironment of the biofilm,thereby alleviating its hypoxic *** near-infrared(NIR)irradiation,the nanoplatform converts O_(2)into a significant amount of singlet oxygen(^(1)O_(2))and heat to eradicate *** generated heat enhances the release of O_(2),accelerates the generation of^(1)O_(2)in PDT,increases cell membrane permeability,and increases bacterial sensitivity to^(1)O_(2).This nanoplatform significantly improves the efficacy of PDT in eradicating biofilm-dwelling bacteria without fostering drug *** on biofilm eradication demonstrate that this nanoplatform can eradicate over 99.9999%of methicillin-resistant Staphylococcus aureus(MRSA)biofilms under 5-min NIR ***,these integrated advantages enable the system to promote the healing of MRSA biofilm-infected wounds with negligible toxicity in vivo,indicating great promise for overcoming the obstacles associated with bacterial biofilm eradication.

关键词： Bacterial biofilm Multidrug-resistant bacteria Photodynamic therapy Oxygen supplying Photothermal therapy

Introduction of rare-earth element Sc in alloy design to modify wear features of dual-phase high-entropy alloy

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Rare Metals 2024年第2期43卷 817-828页

作者： Hao Ren Rui-Run chen Xue-Feng Gao Tong Liu Gang Qin yu-Lung Chiu Shi-Ping wu Jing-Jie Guo Guo National Key Laboratory for Precision Hot Processing of Metals School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin150001China School of Metallurgy and Materials University of BirminghamBirminghamB152TTUK

Tailoring the alloy composition,which induces the hard secondary phase to increase hardness and strength to improve the wear features,is a feasible approach for developing wear-resistant metal ***,a group of(AlCoCrFeNi)_(100–x)Sc_(x)(x=0–2.0,at%)high-entropy alloys(HEAs)are designed and the phase compositions and wear behaviors are ***-doped HEA series contain the primary body-centered cubic(BCC)and eutectic phases,in which the eutectic phase is composed of the alternately grown BCC and Laves *** addition promotes the diffusion of Ni atoms from BCC phase to form the Sc-rich Laves phase at the grain *** hardness increases due to solid solution strengthening and second phase *** the second phase strengthening plays a more significant role relative to solid solution *** phase and the oxides caused by wear heating prevent the direct contact between friction pair and HEAs,thus inducing a decreased wear rate from 6.82×10^(−5) to 3.47×10^(−5)m^(3)·N^(−1)·m^(−1).Moreover,the wear mechanism changes from adhesive wear,abrasive wear and oxidative wear to abrasive wear and oxidative wear.

关键词： High entropy alloy(HEA) Laves phase Hardness Wear mechanism