检索结果-南通市图书馆

Copper release and ROS in antibacterial activity of Ti-Cu alloys against implant-associated infection

Rare Metals 2023年第6期42卷 2007-2019页

作者： Hai-Lin Yang Ling Zou Akram Nasser Juaim chen-xu ma Meng-Zhen Zhu Fei xu Xiao-Na chen Yin-Zhou Wang Xiong-Wen Zhou State Key Laboratory of Powder Metallurgy Central South UniversityChangsha410083China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha410008China Department of Prosthodontics Center of StomatologyXiangya HospitalCentral South UniversityChangsha410008China Department of Oral Implantology Xiangya Stomatological Hospital and Xiangya School of StomatologyCentral South UniversityChangsha410008China Department of Prosthodontics Faculty of DentistryThamar UniversityDhamarYM999101Yemen Center of Stomatology Xiangya HospitalCentral South UniversityChangsha410008China

Enhancing the antibacterial properties of the currently used implant materials is a major concern of healthcare providers to minimize the impact of peri-implant infection and improve implant survival *** this study,titanium-copper sintered alloys(3 wt% and 5 wt%Cu) were developed for medical implant *** phase identification,microstructure,copper ions release,and wettability of these alloys were evaluated using X-ray diffraction(XRD),optical microscope(OM),scanning electron microscope(SEM),transmission electron microscope(TEM),energy-dispersive X-ray spectroscope(EDS),inductively coupled plasma spectroscope(ICP) and drop shape *** antibacterial activities of Ti-Cu alloys against Porphyromonas gingivalis and Streptococcus mutans were evaluated using inhibition zone assay,plate counting assay,live/dead fluorescent staining,SEM and reactive oxygen species(ROS) staining *** results demonstrated that Ti-Cu alloys are composed of α-Ti and Ti_(2)Cu phases that increased with increased Cu content of the ***-Cu alloys exhibited antibacterial activity against both bacteria species in a time-dependent *** antibacterial rates of Ti-3Cu and Ti-5Cu after72 h were 57% and 70% against Porphyromonas gingivalis and 63% and 78% against Streptococcus mutans,*** highest amount of Cu^(2+) released from these alloys was 0.3 mg·L^(-1) during the first 24 h,within the safe *** copper ions release and ROS production were suggested as the main antibacterial ***,Ti-Cu sintered alloys are promising materials for dental and orthopedic implants.

关键词： Titanium-copper alloy Antibacterial Dental implant Ti_(2)Cu Copper release

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Antibacterial activity and mechanism of newly developed Zr-30Ta and Zr-25Ta-5Ti alloys against implant-associated infection

引用

Rare Metals 2022年第12期41卷 4176-4187页

作者： Hai-Lin Yang Akram Nasser Juaim Ling Zou Meng-Zhen Zhu Xiao-Na chen chen-xu ma Xiong-Wen Zhou State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008China Department of Prosthodontics Center of StomatologyXiangya HospitalCentral South UniversityChangsha 410008China Department of Prosthodontics Faculty of DentistryThamar UniversityDharmarYemen Department of Oral Implantology Xiangya Stomatological Hospital and School of StomatologyCentral South UniversityChangsha 410008China

Infection is a common problem after implantation,and the currently used Ti-based implants have insufficient antibacterial *** newly developed Zr-30Ta and Zr-25Ta-5Ti alloys exhibited good mechanical properties,low elastic moduli,and high corrosion *** this work,their antibacterial activities and antibacterial mechanisms were *** surface roughness,wettability,and charge of the alloys were evaluated using a profilometer,drop shape analyzer,and electrokinetic analyzer,*** antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis was investigated using the inhibition zone assay,plate count assay,live/dead staining,and scanning electron microscopy(SEM).The reactive oxygen species release(ROS)was evaluated using the 2’7’-dichlorodihydrofluorescein diacetate(DCFH-DA)*** results demonstrated that Zr-30Ta and Zr-25Ta-5Ti alloys had favorable smooth,hydrophilic,negatively charged surfaces that decreased bacteria adhesion and prevented biofilm ***-30Ta and Zr-25Ta-5Ti alloys also exhibited a time-dependent decrease in the bacteria adhesion and ***-30Ta and Zr-25Ta-5Ti alloys were also found to induce direct membrane damage and increase ROS production,resulting in significantly better antibacterial activities than ***-30Ta and Zr-25Ta-5Ti alloys exhibited comparable antibacterial *** work suggests that the newly developed Zr-30Ta and Zr-25Ta-5Ti alloys have good antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis and are promising candidate materials for dental and orthopedic implants.

关键词： Zirconium-tantalum Dental implant Antibacterial Peri-implant infection Biofilm

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Optimization of mechanical and antibacterial properties of Ti-3wt%Cu alloy through cold rolling and annealing

引用

Rare Metals 2022年第2期41卷 610-620页

作者： Hai-Lin Yang Meng-Zhen Zhu Jian-Ying Wang chen-xu ma Xiong-Wen Zhou Hai-Xia Xing Er-Lin Zhang Shou-xun Ji State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China Department of Prosthodontics Centre of StomatologyXiangya HospitalCentral South UniversityChangsha 410008China Department of General Dentistry Peking University School and Hospital of StomatologyBeijing 100081China Key Laboratory for Anisotropy and Texture of materials School of Materials Science and EngineeringEducation Ministry of ChinaNortheastern UniversityShenyang 110819China Brunel Centre for Advanced Solidification Technology(BCAST) Brunel University LondonUxbridge UB83PHUK

In this work,a process of cold rolling with 70%thickness reduction and different annealing temperatures was selected to regulate the microstructure of Ti-3wt%Cu *** evolution,mechanical properties and antibacterial properties of the Ti-3wt%Cu alloy under different conditions were systematically investigated in terms of X-ray diffraction(XRD),scanning electron microscope(SEM),transmission electron microscope(TEM),tensile and antibacterial *** results indicated that cold rolling could dramatically increase the ultimate tensile stress(UTS)from 520 to 928 MPa,but reduce the fracture strain from 15.3%to 3.8%.With the annealing temperature increasing from 400 to 800C for 1 h,the UTS decreased from 744 to 506 MPa and the fracture strain increased from12.7%to 24.4%.Moreover,the antibacterial properties of the Ti-3wt%Cu alloy under different conditions showed excellent antibacterial rate(>96.69%).The results also indicated that the excellent combination of strength and ductility of the Ti-3wt%Cu alloy with cold rolling and following annealing could be achieved in a trade-off by tuning the size and distribution of Ti2Cu phase,which could increase the applicability of the alloy in clinical *** importantly,the antibacterial properties maintained a good stability for the Ti-3wt%Cu alloy under different *** excellent combination of mechanical properties and antibacterial properties could make the Ti-3wt%Cu alloy a good candidate for long-term orthopaedic implant application.

关键词： Titanium alloys Mechanical properties Antibacterial property Microstructure Plastic deformation Orthopaedic implant application

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A surface engineering strategy for the stabilization of zinc metal anodes with montmorillonite layers toward long-life rechargeable aqueous zinc ion batteries

引用

Journal of Energy Chemistry 2025年第1期100卷 94-105页

作者： Wenbo Wang Ruifeng xu xu Zhang Peiyu Wang Bao Yang Bingjun Yang Juan Yang Kailimai Su Pengjun ma Yanan Deng Xianfeng Fan Wanjun chen Key Laboratory for Electronic materials College of Electrical Engineering Northwest Minzu University Resource Chemistry and Energy materials Research Center State Key Laboratory of Solid Lubrication Lanzhou Institute of Chemical Physics Chinese Academy of Sciences University of Chinese Academy of Sciences Institute for materials and Processes School of Engineering University of Edinburgh

Rechargeable aqueous zinc-ion batteries （AZIBs） exhibit appreciable potential in the domain of electrochemical energy ***,there are serious challenges for AZIBs,for instance zinc dendrite growth,hydrogen evolution reaction （HER）,and corrosion side ***,we propose a surface engineering modification strategy for coating the montmorillonite （MMT） layer onto the surface of the Zn anode to tackle these issues,thereby achieving high cycling stability for rechargeable *** results reveal that the MMT layer on the surface of the Zn anode is able to provide ordered zincophilic channels for zinc ions migration,facilitating the reaction kinetics of zinc *** functional theory（DFT） calculations and water contact angle （CA） tests prove that MMT@Zn anode exhibits superior adsorption capacity for Zn2+and better hydrophobicity than the bare Zn anode,thereby achieving excellent cycling ***,the MMT@Zn||MMT@Zn symmetric cell holds the stable cycling over 5600 h at 0.5 ma cm-2and 0.125 m A h cm-2,even exceeding 1800 h long cycling under harsh conditions of 5 m A cm-2and 1.25 m A h *** MMT@Zn||V2O5full cell reaches over 3000 cycles at 2 A g-1with excellent rate ***,this surface engineering modification strategy for enhancing the electrochemical performance of AZIBs represents a promising application.

关键词： Hydrogen evolution reaction

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

New glucocerebrosidase antibodies can advance research in the field of neurodegenerative disorders

引用

Neural Regeneration Research 2025年第4期20卷 1085-1086页

作者： Charis ma Krystyna Rytel Yu chen Ellen Sidransky Medical Genetics Branch National Human Genome Research InstituteNational Institutes of HealthBethesdaMDUSA

In medical research,there are times when the introduction of a new tool can launch scientific discovery in new *** antibody development may be considered mundane,in the field of glucocerebrosidase(GCase)research,the dearth of validated antibodies for different applications has impeded progress in studies of disease pathogenesis and therapeutic *** recent introduction of new,rigorously evaluated antibodies can now propel research into the link between glucocerebrosidase and Parkinson’s disease(PD)as well as aspects of the pathobiology of Gaucher disease(Jong et al.,2024).

关键词： antibodies cerebro

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rational design of lipid-activatable NIR-II probes for precisely imaging atherosclerotic plaque

引用

Science China Chemistry 2025年

作者： Xinyu xu Yuan ma Hui Cao Li xu Haoming chen Sulai Liu Wei Sun Guosheng Song Xiaobing Zhang State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical EngineeringHunan University Department of Hepatobiliary Surgery/Central Laboratory Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University) Department of Cardiology the First Affiliated Hospital of Nanjing Medical University Key Laboratory of Targeted Intervention of Cardiovascular Disease Collaborative Innovation Center for Cardiovascular Disease Translational MedicineNanjing Medical University Shenzhen Research Institute of Hunan University

Atherosclerosis(AS) is a prevalent condition associated with cardiovascular and cerebrovascular diseases, featuring lipid-laden plaque; however, the insufficient resolution and low sensitivity of traditional medical imaging techniques limit their application in lipid imaging. Currently, the second near-infrared(NIR-II) fluorescence imaging offers promising sensitivity and convenience. However, existing probes have limitations in terms of signal-to-background ratio, penetration depth, and tissue scattering. Herein, we use a molecular regulatory strategy to design a lipid-activatable probe Rh-965 with high specificity and NIR-II emission for improved imaging potential in deep tissues. The potential of Rh-965 for imaging plaque lipids in mice with AS is demonstrated by localizing carotid artery plaques using NIR-II imaging. The development of more stable lipid-activated NIR-II probes can significantly enhance atherosclerosis diagnosis and facilitate in vivo imaging in deeper tissues.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Analysis of Micromechanical Properties at the Interface of Pre-wet SBS Modified Asphalt Mixture Based on Molecular Simulation Technology

引用

Journal of Wuhan University of Technology(materials Science) 2025年第1期40卷 103-113页

作者： chen Wuxing chen Shuang YU Yan ZHANG Jiangyi xu Haiyang GUO Wei School of Mines China University of Mining and TechnologyXuzhou 221000China College of Construction Engineering Jilin Uni-versityChangchun 130026China

The pre-wetting of aggregate surface is a means to improve the interface performance of SBS modified asphalt and *** effect of pre-wetting technology on the interaction between SBS modified asphalt and aggregate was analyzed by molecular dynamics *** diffusion coefficient and concentration distribution of SBS modified asphalt on aggregate surface are *** simulation results show that the diffusion coefficient of the aggregate surface of SBS modified asphalt is increased by 47.6%and 70.5%respectively after 110#asphalt and 130#asphalt are *** concentration distribution of SBS modified asphalt on the aggregate surface after pre-wetting is more *** to the results of interface energy calculation,the interface energy of SBS modified bitumen and aggregate can be increased by about 5%after *** to the results of molecular dynamics simulation,the pre-wetting technology can effectively improve the interface workability of SBS modified bitumen and aggregate,so as to improve the interface performance.

关键词： pre-wet oil-stone interface interface interaction interface mechanics molecular dynamics simulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rapid and scalable preparation of highly quaternized polymer networks to achieve efficient simultaneous adsorption of iodide and pertechnetate

引用

Science China Chemistry 2025年第1期68卷 337-349页

作者： Meiyun xu Song Gu Fulong chen Zhe Zhao Peng Liu Daoben Hua State Key Laboratory of Radiation Medicine and Protection School of Radiological and Interdisciplinary Sciences (RAD-X) Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions Soochow University

The efficient separation of fission products,such as TcO4-and I-,holds strategic significance for the management of radioactive wastes and environmental *** this study,we propose an ultrafast strategy for scalable preparation of a highly quaternized organic network to facilitate efficient and synchronous separation of iodide and *** network can be prepared within a few minutes at room temperature,using polyethylenimine and 1,2,4,5-tetrakis（bromomethyl）benzene as building *** chlorine replacement,the network,abundantly decorated with quaternary ammonium groups （Cl@QPN）,exhibits an ultrahigh positive charge density of 7.6 mmol/*** enables the rapid and efficient enrichment of target anions through strong electrostatic Coulomb *** a result,Cl@QPN exhibits significantly higher adsorption rate constants of 0.830 g/（mg min） for ReO4-（a nonradioactive surrogate of TcO4-） and 0.677 g/（mg min） for I-compared to other ***,it possesses high adsorption capacities,reaching 1,681 mg/g for ReO4-and 917.4 mg/g for I-.Cl@QPN also demonstrates good selectivity towards target ions and shows efficient adsorption for99TcO4-.Additionally,Cl@QPN exhibits high dynamic processing capacities,handling up to 3,100 and 7,400 kg of simulated streams per kilogram of material for I-and ReO4-,respectively.

关键词： quaternized polymer networks adsorption pertechnetate iodide liquid radioactive streams

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

mainchain conformation ordering self-assembly tailored room temperature phosphorescence emission

引用

Science China Chemistry 2025年第1期68卷 329-336页

作者： Yuzhu Li Yumeng Gao Feng Tian Yu Wang Yuan Yao Shaoliang Lin Xiang ma Binbin xu Shanghai Key Laboratory of Advanced Polymeric materials Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science and Technology Shanghai Synchrotron Radiation Facility Shanghai Advanced Research Institute Chinese Academy of Sciences Key Laboratory for Advance materials and Feringa Noble Prize Scientist Joint Research Centre Frontiers Science for Materiobiology and Dynamic Chemistry School of Chemistry and Molecular Engineering East China University of Science & Technology

Developing organic room-temperature phosphorescence （RTP） materials with a wide range of tunable-emission is significant in expanding the applications of RTP ***,we rationally designed amphiphilic alternating copolymers poly(1,2-bis（4-alkoxyphenyl）ethane-1,2-dione-alt-（ethylene glycol）x)(P（Bz-alt-EGx）) that combined the advantage of alternating benzil and EGxskeleton,and tunable mainchain *** a mainchain conformation ordering assembly （COA） process,P（Bz-alt-EGx） self-assembled into well-defined platelets,and such assemblies emitted blue RTP at ca.425 nm due to the ordered folded-chain conformation and confined *** contrast,traditional self-assembly （TA） of P（Bz-alt-EGx） obtained less ordered aggregates,such as asymmetric worms,vesicles,and rod-like *** resultant less ordered aggregates exhibited yellow-green RTP at ca.550 *** wide-tuning RTP emission in solution （between blue and yellow-green,over125 nm） is realized using the P（Bz-alt-EGx） alternating copolymers under the treatment of different self-assembly *** study uncovers a new strategy to tailor the RTP emission through different self-assembly pathways and holds great promise for the fabrication of advanced optical materials.

关键词： self-assembly conformation ordering alternating copolymer phosphorescence emission

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice

引用

Neural Regeneration Research 2025年第9期20卷 2727-2736页

作者： Yujia Liu xue Han Yan Su Yiming Zhou Minhui xu Jiyan xu Zhengliang ma Xiaoping Gu Tianjiao Xia Department of Anesthesiology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina Medical School Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory of Molecular Medicine Nanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjingJiangsu ProvinceChina Department of Anesthesiology Zhongshan HospitalFudan UniversityShanghaiChina

Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life of *** date,there are no viable treatment options for postoperative cognitive *** identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future *** identify the signaling mechanisms contributing to postoperative cognitive dysfunction,we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset,which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus3 days after tibial *** dataset was enriched in genes associated with the biological process"regulation of immune cells,"of which Chill was identified as a hub ***,we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fractu re *** were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 124 hours post-surgery,and the injection groups were compared with untreated control mice for learning and memory capacities using the Y-maze and fear conditioning *** addition,protein expression levels of proinflammatory factors(interleukin-1βand inducible nitric oxide synthase),M2-type macrophage markers(CD206 and arginase-1),and cognition-related proteins(brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B)were measured in hippocampus by western *** with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment,downregulated interleukin-1βand nducible nitric oxide synthase expression,and upregulated CD206,arginase-1,pNR2B,and brain-derived neurotropic factor expr

关键词： Chil1 hippocampus learning and memory M2 microglia neuroinflammation postoperative cognitive dysfunction(POCD) recombinant CHI3L1

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：