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Migration mechanism and risk assessment of perand polyfluoroalkyl substances in the Ya'Er Lake oxidation pond area,China

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Journal of Environmental Sciences 2024年第2期136卷 301-312页

作者： chang Li Huifang Zhong Jing Wu Lingyi Meng Yingjun wang Chunyang Liao Yawei wang Yujian He University of Chinese Academy of Sciences Beijing 100049China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Institute of Biomedical and Health Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China China National Environmental Monitoring Centre Beijing 100012China Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances Institute of Environment and HealthJianghan UniversityWuhan 430056China

The migration mechanisms,sources,and environmental risks of 29 legacy and emerging perfluorinated and polyfluoroalkyl species present in an oxidation pond(Ya'Er Lake)were investigated for treating sewage based on the analysis of their occurrence and *** concentration of per-and polyfluoroalkyl substances(PFAS)in pond area was between0.30 and 63.2 ng/g dw(dry weight),with the overall average concentration of 8.00 ng/g ***,the PFAS concentrations in the surface sediments near the sewage outlet in Pond-1(50.2 ng/g dw)and Pond-5(average 15.1 ng/g dw)were 1–2 orders of magnitude higher than those in other *** general,the legacy PFAS,i.e.,perfluorooctane sulfonic acid was considered to be the major pollutant in the polluted area,on average,accounting for 73.0%of the total concentration of PFAS *** evaluating the regional distribution of different PFAS homologs,the short-chain PFAS pollutants with lower K_(ow)were found to migrate farther in both horizontal and vertical *** sewage outlets in Pond-1 and Pond-5are the main pollution sources in polluted area and the emerging PFAS pollutants in Pond-5have replaced the legacy PFAS pollutants as the main *** on positive matrix factorization analysis,three main industrial sources of PFAS pollutants in the study area were identified:protective coating,fire-fighting,and food packaging ***,the environmental risk assessment results showed that most study areas exhibited medium environmental risk(0.01≤Risk quotient(RQ)<1),indicating that the ecological environment risks in this area need further attention.

关键词： Perfluoroalkyl substances Distribution Migration mechanism Risk assessment

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Single-incision laparoscopic transabdominal preperitoneal repair in the treatment of adult female patients with inguinal hernia

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World Journal of Gastrointestinal Surgery 2024年第1期16卷 49-58页

作者： Xiao-Jun Zhu Jing-Yi Jiao Hui-Min Xue Peng chen chang-Fu Qin Peng wang Department of General Surgery The Affiliated Hospital of Nantong UniversityNantong 226001Jiangsu ProvinceChina Medical School Nantong UniversityNantong 226001Jiangsu ProvinceChina Department of Hernia and Abdominal Wall Surgery Peking University People's HospitalBeijing 100044China

BACKGROUND Women have a 3%lifetime chance of developing an inguinal hernia,which is not as common in *** to its cosmetic benefits,single-incision laparoscopic transabdominal preperitoneal(SIL-TAPP)inguinal hernia repair is becoming in-creasingly popular in the management of inguinal hernia in ***,there are no studies comparing the safety and applicability of SIL-TAPP repair with conventional laparoscopic transabdominal preperitoneal(CL-TAPP)inguinal hernia repair for the treatment of inguinal hernia in *** To compare the outcomes of SIL-TAPP and CL-TAPP repair in adult female patients with inguinal hernia and to estimate the safety and applicability of SIL-TAPP repair in adult female inguinal hernia *** We retrospectively compared the clinical information and follow-up data of fe-male inguinal hernia patients who underwent SIL-TAPP inguinal hernia repair and those who underwent CL-TAPP inguinal hernia repair at the Affiliated Hos-pital of Nantong University from February 2018 to December 2020 and assessed the long-term and short-term outcomes of both *** This study included 123 patients,with 71 undergoing SIL-TAPP repair and 52 un-dergoing CL-TAPP *** two cohorts of patients and inguinal hernia charac-teristics were similar,with no statistically meaningful *** rate of intraoperative inferior epigastric vessel injury was lower in patients in the SIL-TAPP cohort(0,0%)than in patients in the CL-TAPP cohort(4,7.7%)and was significantly different(P<0.05).In addition,the median[interquartile range(IQR)]total hospitalization costs were significantly lower in patients in the SIL-TAPP cohort[$3287(3218-3325)]than in patients in the CL-TAPP cohort[$3511(3491-3599)].Postoperatively,the occurrence rate of trocar site hernia was lower in the SIL-TAPP cohort(0,0%)than in the CL-TAPP cohort(4,7.7%),and the median(IQR)cosmetic score was significantly higher in the SIL-TAPP cohort[10(10-10)]than in the CL-TAPP cohort[9(9

关键词： Single-incision Groin hernia Female Inguinal hernia Laparoscopic transabdominal preperitoneal inguinal hernia repair

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Spatial and temporal variation of water clarity in typical reservoirs in the Beijing-Tianjin-Hebei region observed by GF 1-WFV satellite data

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Journal of Oceanology and Limnology 2024年第4期42卷 1048-1060页

作者： chang CAO Junsheng LI Xiaodong JIA Shenglei wang Bo WAN Liaoning Earthquake Agency Shenyang 11000China Key Laboratory of Digital Earth Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100094China International Research Center of Big Data for Sustainable Development Goals Beijing 100094China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China

Rapidly monitoring regional water quality and the changing trend is of great practical and scientific significance,especially for the Beijing-Tianjin-Hebei(BTH)region of China where water resources are relatively scarce and inland water bodies are generally *** remote sensing data of the GF 1 satellite launched in 2013 have characteristics of high spatial and temporal resolution,which can be used for the dynamic monitoring of the water environment in small lakes and ***,the water quality remote sensing monitoring model based on the GF 1 satellite data for lakes and reservoirs in BTH is still lacking because of the considerable differences in the optical characteristics of the lakes and *** this paper,the typical reservoirs in BTH-Guanting Reservoir,Yuqiao Reservoir,Panjiakou Reservoir,and Daheiting Reservoir are taken as the study *** the atmospheric correction of GF 1-WFV,the relative radiation normalized atmospheric correction was adopted after comparing it with other methods,such as 6 S and *** the water clarity retrieval,a water color hue angle based model was proposed and outperformed other available published models,with the R 2 of 0.74 and MRE of 31.7%.The clarity products of the four typical reservoirs in the BTH region in 2013-2019 were produced using the GF 1-WFV *** on the products,temporal and spatial changes in clarity were analyzed,and the main influencing factors for each water body were *** was found that the clarity of Guanting,Daheiting,and Panjiakou reservoirs showed an upward trend during this period,while that of Yuqiao Reservoir showed a downward *** the influencing factors,the water level of the water bodies can be an important factor related to the water clarity changes in this region.

关键词： GF 1 satellite atmospheric correction clarity Beijing-Tianjin-Hebei spatial and temporal change analysis

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Development of CONTHAC-3D and hydrogen distribution analysis of HPR1000

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Nuclear Science and Techniques 2024年第2期35卷 210-221页

作者： Hui wang Jing-Jing Li Yuan chang Gong-Lin Li Ming Ding China Nuclear Power Engineering Co.LTD. Beijing 100084China Fundamental Science on Nuclear Safety and Simulation Technology Laboratory Harbin 100049China

An in-house code,CONTHAC-3D,was developed to calculate and analyze thermal-hydraulic phenomena in containments during severe ***-3D is a three-dimensional computational fluid dynamics code that can be applied to predict gas flow,diffusion,and steam condensation in a containment during a severe hypothetical accident,as well as to obtain an estimate of the local hydrogen concentration in various zones of the ***-3D was developed using multiple models to simulate the features of the proprietary systems and equipment of HPR1000 and ACP100,such as the passive cooling system,passive autocatalytic recombiners and the passive air cooling *** validate CONTHAC-3D,a GX6 test was performed at the Battelle Model Containment *** hydrogen concentration and temperature monitored by the GX6 test are accurately predicted by ***,the hydrogen distribution in the HPR1000 containment during a severe accident was *** results show that the hydrogen removal rates calculated using CONTHAC-3D for different types of PARs agree well with the theoretical values,with an error of less than 1%.As the accident progresses,the hydrogen concentration in the lower compartment becomes higher than that in the large space,which implies that the lower compartment has a higher hydrogen risk than the dome and large space at a later stage of the *** amount of hydrogen removed by the PARs placed on the floor of the compartment is small;therefore,raising the installation height of these recombiners appropriately is ***,we do not recommend installing all autocatalytic recombiners at high *** study findings in regard to the hydrogen distribution in the HPR1000 containment indicate that CONTHAC-3D can be applied to the study of hydrogen risk containment.

关键词： Hydrogen risk mitigation Pressurized water reactor HPR1000 Thermal hydraulic CONTHAC-3D

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Ion and electron motions in the outer electron diffusion region of collisionless magnetic reconnection

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Earth and Planetary Physics 2024年第3期8卷 472-478页

作者： Cong chang QuanMing Lu San Lu Kai Huang RongSheng wang Deep Space Exploration Laboratory School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China Chinese Academy of Sciences(CAS)Center for Excellence in Comparative Planetology CAS Key Laboratory of Geospace EnvironmentHefei 230026China Collaborative Innovation Center of Astronautical Science and Technology Harbin 150001China

Two-dimensional particle-in-cell simulations are performed to study the coupling between ion and electron motions in collisionless magnetic *** electron diffusion region(EDR),where the electron motions are demagnetized,is found to have a two-layer structure:an inner EDR near the reconnection site and an outer EDR that is elongated to nearly 10 ion inertial lengths in the outflow *** the inner EDR,the speed of the electron outflow increases when the electrons move away from the X *** the outer EDR,the speed of the electron outflow first increases and then decreases until the electrons reach the boundary of the outer *** the boundary of the outer EDR,the magnetic field piles up and forms a depolarization *** the perspective of the fluid,a force analysis on the formation of electron and ion outflows has also been *** the X line,the electrons are accelerated by the reconnection electric field in the out-of-plane *** the electrons move away from the X line,we find that the Lorentz force converts the direction of the accelerated electrons to the x direction,forming an electron *** electric field forces and electron gradient forces tend to drag the electron *** acceleration along the x direction is caused by the Lorentz force,whereas the pressure gradient force tends to decelerate the ion *** these two terms are important,their effects on ions are almost *** Hall electric field force does positive work on ions and is not *** ions are continuously accelerated,and the ion and electron outflow velocities are almost the same near the depolarization front.

关键词： collisionless magnetic reconnection electron diffusion region force analysis particle-in-cell simulation

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Research on the generation method of seawater sound velocity model based on Perlin noise

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Acta Oceanologica Sinica 2024年第1期43卷 99-111页

作者： Zhimiao chang Fuxing Han Zhangqing Sun Zhenghui Gao Xueqiu wang College of Geoexploration Science and Technology Jilin UniversityChangchun 130026China

In the processing of conventional marine seismic data,seawater is often assumed to have a constant velocity ***,due to static pressure,temperature difference and other factors,random disturbances may often frequently in seawater *** impact of such disturbances on data processing results is a topic of theoretical *** seawater sound velocity is a difficult physical quantity to measure,there is a need for a method that can generate models conforming to seawater *** article will combine the Munk model and Perlin noise to propose a two-dimensional dynamic seawater sound velocity model generation method,a method that can generate a dynamic,continuous,random seawater sound velocity model with some regularity at large ***,the paper discusses the influence of the inhomogeneity characteristics of seawater on wave field propagation and *** results show that the seawater sound velocity model with random disturbance will have a significant influence on the wave field simulation and imaging results.

关键词： Munk model Perlin noise seawater inhomogeneity

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Organic near-infrared optoelectronic materials and devices:an overview

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Advanced Photonics 2024年第1期6卷 17-42页

作者： Zong-Lu Che chang-Cun Yan Xue-Dong wang Liang-Sheng Liao Soochow University Institute of Functional Nano and Soft Materials(FUNSOM)Jiangsu Key Laboratory for Carbon-Based Functional Materials and DevicesSuzhouChina Soochow University College of ChemistryChemical Engineering and Materials ScienceJiangsu Engineering Laboratory of Novel Functional Polymeric MaterialsSuzhouChina Macao University of Science and Technology Macao Institute of Materials Science and EngineeringMacaoChina

Near-infrared(NIR)light has shown great potential for military and civilian applications owing to its advantages in the composition of sunlight,invisibility to human eyes,deeper penetration into biological tissues,and low optical loss in optical ***,organic optoelectronic materials that can absorb or emit NIR light have aroused great scientific interest in basic science and practical *** on these NIR organic optoelectronic materials,NIR optoelectronic devices have been greatly improved in performance and *** this review,the representative NIR organic optoelectronic materials used in organic solar cells,organic photodetectors,organic light-emitting diodes,organic lasers,and organic optical waveguide devices are briefly introduced,and the potential applications of each kind of device are briefly ***,we summarize and take up the development of NIR organic optoelectronic materials and devices.

关键词： near-infrared organic optoelectronic materials organic solar cells organic light-emitting devices organic optical waveguides

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Decitabine induces IRF7-mediated immune responses in p53-mutated triple-negative breast cancer:a clinical and translational study

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Frontiers of Medicine 2024年第2期18卷 357-374页

作者： Haoyu wang Zhengyuan wang Zheng wang Xiaoyang Li Yuntong Li Ni Yan Lili Wu Ying Liang Jiale Wu Huaxin Song Qing Qu Jiahui Huang Chunkang chang Kunwei Shen Xiaosong chen Min Lu Department of General Surgery Comprehensive Breast Health CenterRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200025China Shanghai Institute of Hematology State Key Laboratory of Medical GenomicsNational Research Center for Translational Medicine(Shanghai)Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200025China Department of Hematology Shanghai Institute of HematologyRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai200025China Department of Hematology Shanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghai200025China

p53 is mutated in half of cancer ***,no p53-targeting drugs have been ***,we reposition decitabine for triple-negative breast cancer(TNBC),a subtype with frequent p53 mutations and extremely poor *** a retrospective study on tissue microarrays with 132 TNBC cases,DNMT1 overexpression was associated with p53 mutations(P=0.037)and poor overall survival(OS)(P=0.010).In a prospective DEciTabinE and Carboplatin in TNBC(DETECT)trial(NCT03295552),decitabine with carboplatin produced an objective response rate(ORR)of 42%in 12 patients with stage IV *** the 9 trialed patients with available TP53 sequencing results,the 6 patients with p53 mutations had higher ORR(3/6 vs.0/3)and better OS(16.0 vs.4.0 months)than the patients with wild-type *** a mechanistic study,isogenic TNBC cell lines harboring DETECT-derived p53 mutations exhibited higher DNMT1 expression and decitabine sensitivity than the cell line with wild-type *** the DETECT trial,decitabine induced strong immune responses featuring the striking upregulation of the innate immune player IRF7 in the p53-mutated TNBC cell line(upregulation by 16-fold)and the most responsive patient with *** integrative studies reveal the potential of repurposing decitabine for the treatment of p53-mutated TNBC and suggest IRF7 as a potential biomarker for decitabine-based treatments.

关键词： p53 mutation triple-negative breast cancer decitabine DNMT1 IRF7 innate immune response

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75 mW robust single frequency Yb-doped DFB fiberBragg grating laser

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Chinese Science Bulletin 2008年第17期53卷 2729-2732页

作者： chen JiaLin wang Li chang LiPing LI GuoYang chen Bai LIN ZunQi Shanghai Institute of Optics and Fine Mechanics Chinese Academy of Sciences Shanghai 201800 China

Incorporating the shielded method and post-processing method, a 75 mW single frequency Yb-doped DFB fiber laser was obtained with a 250 mW laser diode pump source at 978 nm. The threshold of the laser is 2 mW. The laser is single-polarization operation and the output power fluctuation is less than 0.2 mW in one hour when the pump power is 250 mW.

关键词：光纤布拉格光栅激光器镱掺杂后处理法激光技术

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Prospect of ultrahigh-resolution fast neutron absorption spectroscopy based on a laser plasma electron accelerator

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High Power Laser Science and Engineering 2024年第1期12卷 108-115页

作者： Wen-Zhao wang Jie Feng Xiao-Peng Zhang Yao-Jun Li Wei-Jun Zhou Wen-Chao Yan Guo-Qiang Zhang chang-Bo Fu Li-Ming chen Key Laboratory of Laser Plasma(MoE) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina IFSA Collaborative Innovation Center Shanghai Jiao Tong UniversityShanghaiChina Institute of High Energy Physics Chinese Academy of SciencesBeijingChina Shanghai Advanced Research Institute Chinese Academy of SciencesShanghaiChina Key Laboratory of Nuclear Physics and Ion-beam Application(MoE) Institute of Modern PhysicsFudan UniversityShanghaiChina

Fast neutron absorption spectroscopy is widely used in the study of nuclear structure and element analysis. However,due to the traditional neutron source pulse duration being of the order of nanoseconds, it is difficult to obtain a high-resolution absorption spectrum. Thus, we present a method of ultrahigh energy-resolution absorption spectroscopy via a high repetition rate, picosecond duration pulsed neutron source driven by a terawatt laser. The technology of single neutron count is used, which results in easily distinguishing the width of approximately 20 keV at 2 MeV and an asymmetric shape of the neutron absorption peak. The absorption spectroscopy based on a laser neutron source has one order of magnitude higher energy-resolution power than the state-of-the-art traditional neutron sources, which could be of benefit for precisely measuring nuclear structure data.

关键词： fast neutron absorption spectroscopy laser plasma accelerator photo-nuclear neutrons single neutron count

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