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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon J.Brown Rafael J.Yáñez-muñoz Heidi R.Fuller School of Pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

Optical encryption with cascaded fractional wavelet transforms

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第8期7卷 1431-1435页

作者： BAO liang-hua chen Lin-fei ZHAO Dao-mu Department of Phvsics Zhejiang University Hangzhou 310027 China Department of Physics Zhejiang Education College Hangzhou 310012 China

On the basis of fractional wavelet transform, we propose a new method called cascaded fractional wavelet transform to encrypt images. It has the virtues of fractional Fourier transform and wavelet transform. Fractional orders, standard focal lengths and scaling factors are its keys. multistage fractional Fourier transforms can add the keys easily and strengthen information se-curity. This method can also realize partial encryption just as wavelet transform and fractional wavelet transform. Optical reali-zation of encryption and decryption is proposed. Computer simulations confirmed its possibility.

关键词： Wavelet transform (WT) Cascaded fractional wavelet transform (CFWT) Encryption Decryption

Role of Parameter Errors in the Spring Predictability Barrier for ENSO Events in the Zebiak–Cane Model

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Advances in Atmospheric Sciences 2014年第3期31卷 647-656页

作者： YU liang mu mu Yanshan YU Key Laboratory of Ocean Circulation and Waves Institute of Oceanology Chinese Academy of Sciences University of Chinese Academy of Sciences School of Mathematical Sciences Monash University Clayton Victoria

ABSTRACT The impact of both initial and parameter errors on the spring predictability barrier （SPB） is investigated using the Zebiak Cane model （ZC model）. Previous studies have shown that initial errors contribute more to the SPB than parameter errors in the ZC model. Although parameter errors themselves are less important, there is a possibility that nonlinear interactions can occur between the two types of errors, leading to larger prediction errors compared with those induced by initial errors alone. In this case, the impact of parameter errors cannot be overlooked. In the present paper, the optimal combination of these two types of errors [i.e., conditional nonlinear optimal perturbation （CNOP） errors] is calculated to investigate whether this optimal error combination may cause a more notable SPB phenomenon than that caused by initial errors alone. Using the CNOP approach, the CNOP errors and CNOP-I errors （optimal errors when only initial errors are considered） are calculated and then three aspects of error growth are compared：（1） the tendency of the seasonal error growth; （2） the prediction error of the sea surface temperature anomaly; and （3） the pattern of error growth. All three aspects show that the CNOP errors do not cause a more significant SPB than the CNOP-I errors. Therefore, this result suggests that we could improve the prediction of the E1 Nifio during spring by simply focusing on reducing the initial errors in this model.

关键词： ENSO predictability spring predictability barrier initial errors parameter errors error growth

Lane Detection:A Survey with New Results

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Journal of Computer Science & Technology 2020年第3期35卷 493-505页

作者： Dun liang Yuan-chen Guo Shao-Kui Zhang Tai-Jiang mu Xiaolei Huang Department of Computer Science and Technology BNRistTsinghua UniversityBeijing100084China College of Information Sciences and Technology Pennsylvania State UniversityUniversity ParkPA16802USA

Lane detection is essential for many aspects of autonomous driving,such as lane-based navigation and high-definition(HD)map *** lane detection is challenging especially with complex road conditions,considerable progress has been witnessed in this area in the past several *** this survey,we review recent visual-based lane detection datasets and *** datasets,we categorize them by annotations,provide detailed descriptions for each category,and show comparisons among *** methods,we focus on methods based on deep learning and organize them in terms of their detection ***,we introduce a new dataset with more detailed annotations for HD map modeling,a new direction for lane detection that is applicable to autonomous driving in complex road conditions,a deep neural network LineNet for lane detection,and show its application to HD map modeling.

关键词： convolutional neural network(CNN) dataset deep learning high-definition(HD)map lane detection

Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

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World Journal of Gastroenterology 2025年第1期31卷 58-67页

作者： mu-Hsien Lee cheng-Hui Lin Chi-Huan Wu Yung-Kuan Tsou Kai-Feng Sung Sheng-Fu Wang Nai-Jen Liu Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan 33305Taiwan School of Medicine Chang Gung UniversityTaoyuan 33305Taiwan

BACKGROUND Needle-knife precut papillotomy(NKP)is typically performed ***,it remains unclear whether pancreatic stent(PS)placement can improve the outcomes of *** To explore whether PS placement improves the success rate of NKP in patients with difficult biliary *** This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary *** cases with incidental pancreatic duct cannulation during conventional biliary cannulation,the decision for pre-NKP PS placement was made at the endoscopist's *** primary outcome was the difference in the NKP success rate between patients with and without PS placement;the secondary outcome was the adverse event *** Among the 190 participants,82 received pre-NKP PS(PS-NKP group)whereas 108 did not[freehand or freehand NKP(FH-NKP)group].Post-NKP selective biliary cannulation was successful in 167(87.9%)patients,and the PS-NKP had a significantly higher success rate than the FH-NKP group(93.9%vs 83.3%,P=0.027).The overall adverse event rates were 7.3%and 11.1%in the PS-NKP and FH-NKP groups,respectively(P=0.493).A periampullary diverticulum(PAD)and significant intraoperative bleeding during NKP were independently associated with NKP failure;however,a pre-NKP PS was the only predictor of NKP *** the 44 participants with PADs,the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group(87.5%and 65%,respectively;P=0.076).CONCLUSION PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.

关键词： Difficult biliary cannulation Endoscopic retrograde cholangiopancreatography Needle-knife papillotomy Pancreatic stent Selective biliary cannulation

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自然语言处理研究综述

新疆师范大学学报（哲学社会科学版） 2025年第2期46卷 89-111,F0002页

作者：赵铁军许木璠陈安东哈尔滨工业大学计算学部黑龙江哈尔滨150001

近年来,自然语言处理因在分析与建模人类语言任务领域取得诸多成果而备受关注。当前,大规模预训练语言模型展现出强大的对话问答和文本生成能力,带来自然语言处理研究的新一轮热潮。自然语言处理在机器翻译、文本摘要、信息抽取等领域... 详细信息

近年来,自然语言处理因在分析与建模人类语言任务领域取得诸多成果而备受关注。当前,大规模预训练语言模型展现出强大的对话问答和文本生成能力,带来自然语言处理研究的新一轮热潮。自然语言处理在机器翻译、文本摘要、信息抽取等领域应用广泛。文本首先讨论自然语言处理针对语言学四个不同层次文本信息的分析手段,对自然语言处理的基本任务组成进行概述;其次,讨论自然语言处理在具体下游任务中的应用现状,包括自然语言处理在具体任务中的应用历史、当前的研究趋势以及面临的挑战;最后,在大规模预训练语言模型研究对数据集提出更高要求的背景下,对自然语言处理领域已有的数据集及评测基准集等进行讨论。

关键词：自然语言处理句法分析语义分析机器翻译问答系统信息抽取

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Cysteine-enhanced reductive degradation of nitrobenzene using nano-sized zero-valent iron by accelerated electron transfer

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Journal of Environmental Sciences 2021年第2期33卷 110-116页

作者： Yuanming Peng Yunsong mu Chao Xue Anwei chen liang Peng Haiyong Wu Si Luo College of Resources and Environment Hunan Agricultural UniversityChangsha 410128China School of Enuironment&Natural Resources Renmin University of ChinaBeijing 100872China Soil and Fertilizer Institute of Hunan Province Hunan Academy of Agricultural SciencesChangsha 401125China 不详

As an aliphatic amino acid,cysteine(CYS)is diffuse in the living cells of plants and ***,little is known of its role in the reactivity of nano-sized zero-valent iron(NZVI)in the degradation of *** study shows that the introduction of CYS to the NZVI system can help improve the efficiency of reduction,with 30%more efficient degradation and a reaction rate constant nine times higher when nitrobenzene(NB)is used as probe *** rates of degradation of NB were positively correlated with the range of concentrations of CYS from 0 to 10 mmol/*** introduction of CYS increased the maximum concentration of Fe(Ⅲ)by 12 times and that of Fe(II)by four times in this system.A comparison of systems featuring only CYS or Fe(Ⅱ)showed that the direct reduction of NB was not the main factor influencing its CYS-stimulated *** reduction in the concentration of CYS was accompanied by the generation of cystine(CY,the oxidized form of cysteine),and both eventually became *** introduction of CY also enhanced NB degradation due to NZVI,accompanied by the regeneration of *** supports the claim that CYS can accelerate electron transfer from NZVI to NB,thus enhancing the efficiency of degradation of NB.

关键词： Zero-valent iron Nanoparticles CYS Electron shuttle Reactivity

On spectrum of Hermitizable tridiagonal matrices

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Frontiers of Mathematics in China 2020年第2期15卷 285-303页

作者： mu-Fa chen Research Institute of Mathematical Science Jiangsu Normal UniversityXuzhou 221116China School of Mathematical Sciences Beijing Normal UniversityLaboratory of Mathematics and Complex Systems(Beijing Normal University)Ministry of EducationBeijing 100875China

This paper is devoted to the study on the spectrum of Hermitizable tridiagonal *** an illustration of the application of the author’s recent results on Hermitizable matrices,an explicit criterion for discrete spectrum of the matrices is presented,with a slight and technical *** problem is well known,but from the author’s knowledge,it has been largely opened for quite a long *** is important in various application,in quantum mechanics for *** main tool to solve the problem is the isospectral technique developed a few years *** alternative constructions of the isospectral operator are presented;they are helpful in theoretical analysis and in numerical computations,*** illustrated examples are included.

关键词： Hermitizable birth-death matrix isospectral matrices discrete spectrum

Application of deep eutectic solvents in biomass pretreatment and conversion

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Green Energy & Environment 2019年第2期4卷 95-115页

作者： Yu chen Tiancheng mu School of Chemistry and Material Science Langfang Normal University Department of Chemistry Renmin University of China

Biomass is renewable, abundant, cheap, biocompatible, and biodegradable materials and has been used to produce chemicals, materials,energy, and fuels. However, most of the biomass, especially most of the biomass polymers are not soluble in common solvents, which hinders their pretreatment and conversion. Deep eutectic solvents(DESs) are environmental-friendly, cheap, and highly tunable, with high solubility,which renders them potential applications in biomass pretreatment and conversion. They could be used as solvents or catalysts and so on. This paper intends to review the application of DESs for the pretreatment of biomass and conversion of biomass to value-added products. We focus on the following topics related to biomass and DESs:(1) DESs for the pretreatment of biomass;(2) DESs for the dissolution and separation of biomass or extraction of chemicals from biomass;(3) DESs for biomass conversion;(4) Drawbacks, and recyclability of DESs for pretreatment and conversion of biomass.

关键词： Deep eutectic solvents Biomass Pretreatment Conversion

The functional role of Higd1a in mitochondrial homeostasis and in multiple disease

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Genes & Diseases 2023年第5期10卷 1833-1845页

作者： Jie-Ying Zhu Min chen Wang-Jing mu Hong-Yang Luo liang Guo School of Kinesiology Shanghai University of SportShanghai 200438China Shanghai Frontiers Science Research Base of Exercise and Metabolic Health Shanghai University of SportShanghai 200438China

Higd1a is a conserved gene in evolution which is widely expressed in many tissues in *** evidence has revealed multiple functions of Higd1a,as a mitochon-drial inner membrane protein,in the regulation of metabolic *** plays an impor-tant role in anti-apoptosis and promotes cellular survival in several cell types under hypoxic *** the survival of porcine Sertoli cells facilitated by Higd1a helps to support *** some cases,Higd1a can serve as a sign of metabolic *** the past several years,a considerable amount of studies about how tumor fate is determined and how cancerous proliferation is regulated by Higd1a have been *** this review,we summarize the physiological functions of Higd1a in metabolic homeostasis and its pathophysiological roles in distinct diseases including cancer,nonalcoholic fatty liver disease(NAFLD),type Il diabetes and mitochondrial *** prospect of Higd1a with potential to preserve mammal health is also *** review might pave the way for Higd1a-based research andapplicationinclinicalpractice.

关键词： Apoptosis Cancer Diabetes Mitochondrial homeostasis NAFLD