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Link between pharyngeal acid reflux episodes and the effectiveness of proton pump inhibitor therapy

World Journal of Gastroenterology 2024年第48期30卷 5162-5173页

作者： Yen-Yang chen chen-chi wang Chun-Yi Chuang Yung-An Tsou Yen-Chun Peng chi-Sen Chang Han-Chung Lien Division of Gastroenterology Taichung Veterans General HospitalTaichung 402TaiwanChina Department of Otolaryngology Taichung Veterans General HospitalTaichung 402TaiwanChina School of Medicine National Yang Ming Chiao Tung UniversityTaipei 112TaiwanChina School of Speech Language Pathology and Audiology Chung Shan Medical UniversityTaichung 402TaiwanChina School of Medicine Chung Shan Medical UniversityTaichung 402TaiwanChina Department of Otolaryngology Chung Shan Medical University HospitalTaichung 402TaiwanChina Department of Otorhinolaryngology-Head and Neck Surgery China Medical University HospitalTaichung 400TaiwanChina Division of Gastroenterology and Hepatology Department of Internal MedicineTungs’Taichung Metro Harbor HospitalTaichung 435TaiwanChina Division of Gastroenterology Center for Functional Esophageal DisordersTaichung Veterans General HospitalTaichung 402TaiwanChina Department of Post-Baccalaureate Medicine College of MedicineNational Chung Hsing UniversityTaichung 402Taiwan

BACKGROUND Diagnosing laryngopharyngeal reflux(LPR)is challenging due to overlapping *** proton pump inhibitors(PPIs)are commonly prescribed,reliable predictors of their responsiveness are *** monitoring techno-server *** hypothesized that PAR episodes alone might also predict PPI *** To investigate whether PAR episodes alone predict a positive response to PPI *** Patients suspected of having LPR were prospectively recruited from otolaryngologic clinics in three Taiwan residents tertiary *** underwent a 24-hour esophagopharyngeal pH test using either 3-pH-sensor or hypopha-ryngeal MII-pH catheters while off medication,followed by a 12-week esomeprazole course(40 mg twice daily).Participants were categorized into four groups based on pH results:PAR alone,EAR alone,both pH(+),and both pH(-).The primary outcome was a≥50%reduction in primary laryngeal symptoms,with observers blinded to group *** A total of 522 patients(mean age 52.3±12.8 years,54%male)were *** these,190(mean age 51.5±12.4 years,61%male)completed the treatment,and 89(47%)responded to PPI *** rates were highest in the PAR alone group(73%,n=11),followed by EAR alone(59%,n=68),both pH(+)(56%,n=18),and both pH(-)(33%,n=93).Multivariate analysis adjusting for age,sex,body mass index,and endoscopic esophagitis showed that participants with PAR alone,EAR alone,and both pH(+)were 7.4-fold(P=0.008),4.2-fold(P=0.0002),and 3.4-fold(P=0.03)more likely to respond to PPI therapy,respectively,compared to the both pH(-)*** analyses using the definition of≥1 PAR episode were less *** In the absence of proven hypopharyngeal predictors,this post-hoc analysis found that baseline≥2 PAR episodes alone are linked to PPI responsiveness,suggesting the importance of hypopharyngeal reflux monitoring.

关键词： Pharyngeal acid reflux episodes Laryngopharyngeal reflux Hypopharyngeal multichannel intraluminal impedance-pH 3-pH-sensor Proton pump inhibitors

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1-Methyl-3-octylimidazolium Polyoxomolybdate Ionic Liquid with Low Melting Point and High Stability:Preparation and Photocatalytic Activity

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Chemical Research in chinese Universities 2011年第2期27卷 177-180页

作者： DONG Tao XU Yan-qing chen Fa-wang chi Ying-nan HU Chang-wen State Key Laboratory of Explosion Science and Technology Department of ChemistryInstitute for Chemical Physics Beo＇ing Institute of Technology Beijing 100081 P R. China

The polyoxometalate（POM）-imidazole ionic liquid（IL） [C8mim]2[Mo6O19]（C8mim=1-methyl-3-octylimi- dazolium） with a low melting point of 82.6 °C was successfully prepared and characterized by FTIR, XPS, NMR, TG and so on. The polyoxomolybdate-based IL has high stability, and its decomposing temperature reaches 321 °C, which is higher than that of 1-alkyl-3-methylimidazolium halides IL. Further photocatalytic performances of the IL were measured via degrading dye rhodamine B（RB） in aqueous solution under the UV light irradiation. The experiments show that the conversion of RB reaches 80.5% after 90 min under UV-light and the degradation efficiency depends on the pH value of the solution, irradiation time and the dosage of the IL and so on.

关键词： Ionic liquid Polyoxomolybdate Low melting point High stability Photocatalytic activity

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产业建筑遗存与转型住屋

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新建筑 2003年第2期 4-6页

作者：陈帆王驰浙江大学建筑系杭州310027

在旧城改造如火如荼的今日中国城市,产业建筑作为20世纪数量最大的建筑遗产,正带着城市发展的记忆在人们的视野中消失。拟探讨一种产业建筑的动态保护策略——改造性再利用,并结合我国目前住宅大量紧缺的社会现实,提出了将产业建筑遗... 详细信息

在旧城改造如火如荼的今日中国城市,产业建筑作为20世纪数量最大的建筑遗产,正带着城市发展的记忆在人们的视野中消失。拟探讨一种产业建筑的动态保护策略——改造性再利用,并结合我国目前住宅大量紧缺的社会现实,提出了将产业建筑遗存改造成为转型住屋的建筑设计对策。

关键词：产业建筑转型住屋旧城改造建筑遗产建筑设计

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EXCIPLEX FORMATION INFLUENCED BY ISOMERS——EXCIPLEX FORMED FROM DIMETHYL TEREPHTHALATE AND PHTHALATE WITH 9-ETHYL CARBAZOLE

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Science china Chemistry 1989年第5期32卷 513-521页

作者：陈尚贤陈展翅王竹庭 Institute of Chemistry Academia Sinica Beijing

Both dimethyl terephthalate (DMTP) and dimethyl phthalate are able to form exciplex with 9-ethyl carbazole (EtCz) but the fluorescence quenching constant of DMTP to EtCz is larger than that of DMP to EtCz. The peak positions of the fluorescence bands of the exciplex formed from DMTP and DMP with EtCz are also different. The former gives a peak at shorter wavelength region. Either the exciplex formation rate constant k_3 or the exciplex dissociation rate constant k_4 is not alike. Both of these constants of DMTP are larger than those of DMP. All these results are difficult to explain with the established theory, so a new model which could be used to explain the results satisfactorily is supposed.

关键词： exciplex carbazole fluorescence isomer.

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Heat Transfer Characteristics of Wavy-Wall Channels in Micropolar Fluids

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Tsinghua Science and Technology 2002年第2期7卷 146-154页

作者： Cha’o Kuang chen , chi Chang wang Department of Mechanical Engineering, cheng Kung University, Tainan 701, china Department of Mechanical Engineering Cheng Kung University Tainan 701 China

Forced convection flow through a sinusoidally curved converging diverging channel in micropolar fluids has been investigated numerically. A simple coordinate transformation is employed to transform the complex wavy wall channel to a parallel plate channel, and the cubic spline alternating direction implicit method is then used to solve the flow patterns and heat transfer characteristics. The effects of the wavy geometry, vortex viscosity parameter and Reynolds number on skin friction coefficient and Nusselt number have been examined in detail. Results show that the flow through a sinusoidally curved converging diverging channel forms a strong forward flow and a reticular vortex within each wave for larger Reynolds number and wavy amplitudes. The heat transfer rate of a micropolar fluid is smaller than that of a Newtonian fluid, but the skin friction of a micropolar fluid is larger than that of a Newtonian fluid. Moreover, both Reynolds number and wavy amplitude tend to enhance the total heat transfer rate, irrespective of whether the fluids are Newtonian fluids or micropolar fluids. 

关键词： micropolar fluids forced convection wavy surface cubic spline

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Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： Jie wang Wei wang Xuheng chen Junfang Bao Qiuyue Hao Heng Zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model

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High-energy-density lithium manganese iron phosphate for lithium-ion batteries: Progresses, challenges, and prospects

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Journal of Energy Chemistry 2025年第1期100卷 1-17页

作者： Bokun Zhang Xiaoyun wang Shuai wang Yan Li Libo chen Handong Jiao Zhijing Yu Jiguo Tu State Key Laboratory of Advanced Metallurgy University of Science and Technology Beijing Research Institute for Intelligent Wearable Systems The Hong Kong Polytechnic University Institute of Advanced Structure Technology Beijing Institute of Technology

The soaring demand for smart portable electronics and electric vehicles is propelling the advancements in high-energy–density lithium-ion *** manganese iron phosphate (LiMnxFe1-xPO4) has garnered significant attention as a promising positive electrode material for lithium-ion batteries due to its advantages of low cost,high safety,long cycle life,high voltage,good high-temperature performance,and high energy *** LiMnxFe1-xPO4has made significant breakthroughs in the past few decades,there are still facing great challenges in poor electronic conductivity and Li-ion diffusion,manganese dissolution affecting battery cycling performance,as well as low tap *** review systematically summarizes the reaction mechanisms,various synthesis methods,and electrochemical properties of LiMnxFe1-xPO4to analyze reaction processes accurately and guide material ***,the main challenges currently faced are concluded,and the corresponding various modification strategies are discussed to enhance the reaction kinetics and electrochemical performance of LiMnxFe1-xPO4,including multi-scale particle regulation,heteroatom doping,surface coating,as well as microscopic morphology ***,in view of the current research challenges faced by intrinsic reaction processes,kinetics,and energy storage applications,the promising research directions are *** importantly,it is expected to provide key insights into the development of high-performance and stable LiMnxFe1-xPO4materials,to achieve practical energy storage requirements.

关键词： Lithium manganese iron phosphate High energy density Lithium-ion batteries Reaction mechanism Tap density

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Co-production of hydrogen, oxygen, and electricity via an integrated solar-driven system with decoupled water electrolyzer and Na-Zn ion battery

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Journal of Energy Chemistry 2025年第1期100卷 621-627页

作者： Fei Lv Longjie Liu Jiazhe Wu Pengfei wang Lixia Pan Dengwei Jing Yubin chen International Research Center for Renewable Energy State Key Laboratory of Multiphase Flow in Power Engineering Xi'an Jiaotong University

Combining water electrolysis and rechargeable battery technologies into a single system holds great promise for the co-production of hydrogen （H2） and ***,the design and development of such systems is still in its ***,an integrated hydrogen-oxygen （O2）-electricity co-production system featuring a bipolar membrane-assisted decoupled electrolyzer and a Na-Zn ion battery was established with sodium nickelhexacyanoferrate （NaNiHCF） and Zn2+/Zn as dual redox *** decoupled electrolyzer enables to produce H2and O2in different time and space with almost 100%Faradaic efficiency at 100 mA ***,the charged NaNiHCF and Zn electrodes after the electrolysis processes formed a Na-Zn ion battery,which can generate electricity with an average cell voltage of 1.75 V at 10 m A *** connecting Si photovoltaics with the modular electrochemical device,a well-matched solar driven system was built to convert the intermittent solar energy into hydrogen and electric energy with a solar to hydrogen-electricity efficiency of 16.7%,demonstrating the flexible storage and conversion of renewables.

关键词： Hydrogen Electricity Decoupled water electrolyzer Na-Zn ion battery Solar energy

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MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： Jiaen wang Wei Ming Longfu chen Tianliang Song Moxi Yele Hao Zhang Long Yang Gegen Sarula Benliang Liang Luting Yan Guangsheng wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 MJ m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance

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Surface micro-arrays enhancing electromagnetic interference shielding of polydimethylsiloxane/multiwalled carbon nanotubes nanocomposites

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Nano Research 2025年第1期18卷 508-519页

作者： Ke Jiang Zhi chen Ji Yu chen Zheng Shan Huang Ming wang Chongqing Key Laboratory of Soft-Matter Material Manufacturing School of Chemistry and Chemical EngineeringSouthwest UniversityChongqing 400715China School of Mechanics Civil Engineering and ArchitecturesNorthwestern Polytechnical UniversityXi’an 710072China Jieyang Branch of Chemistry and Chemical Engineering Guangdong Laboratory(Rongjiang Laboratory) Jieyang 515200China

Herein,the electromagnetic shielding performance of surface concave-convex(SC)and zig-zag micro-arrays was studied by using a simulation prediction and a three-dimensional(3D)printing custom ***,surface stripe concaveconvex(SSC)and surface cylindrical concave-convex(SCC)micro-arrays with or without zig-zag micro-arrays are designed,and their shielding performance is simulated in multi-bands(C-,X-band).The multiwalled carbon nanotubes/polydimethylsiloxane composites(MWCNT/PDMS)with different SC structures and different electrical conductivity are molded in acrylonitrile-butadiene-styrene copolymer(ABS)molds which are printed by a 3D *** results show that the electromagnetic interference shielding effectiveness(EMI SE)of the samples can be enhanced by constructing the SC micro-arrays with zig-zag micro-arrays,and improving with the increase of conductivity and *** addition,the shielding mechanism of the SC-MWCNT/PDMS composites is investigated and discussed by an electromagnetic simulation.

关键词： surface micro-arrays electrical properties electromagnetic interference(EMI)shielding three-dimensional(3D)printing

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