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Journal of Materials Science & Technology 1997年第6期13卷 483-486页

作者： Huang, yh.chen, QZ Chu, WY Univ Sci & Technol Beijing Dept Mat Phys Beijing 100083 Peoples R China

Using a special constant deflection device, the in situ TEM observations of dislocation emission, motion and the initiation of nanocrack in 310 stainless steel in water were carried out. The results show that SCC in thin foil specimen of 310 stainless steel can occur in water. A nanocrack initiated in the DFZ or at the blunt crack tip in corrosion solution after dislocation emission, multiplication and motion, which were induced by the localized anodic dissolution, reached a critical condition. The nanocrack propagated by a cleavage mode because of the influence of the corrosion solution.

关键词： Stainless steel

Differential expression of endoplasmic reticulum molecular chaperone Grp94 in human colorectal carcinoma and promyelocytic leukemia cells

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Chinese Science Bulletin 1997年第19期42卷 1651-1655页

作者： chen, yh.Song, JD Key Laboratory of Cell Biology Ministry of Public Health of China China Medical University Shenyang 110001 China

ENDOPLASMIC reticulum (ER) molecular chaperone glucose regulated protein (Grp94 ), a mem-ber of heat shock protein 90 family, is a relatively abundant luminal protein in the ER. Theexpression of the Grp94 gene is markedly increased under many stress conditions. Grp94 isprimarily involved in folding, assembly and translocation of proteins synthesized within

关键词： neoplasms endoplasmic reticulum molecular chaperone Crp94 differential expression.

ISOLATION　AND　DETERMINATION　OF　A　GROUP　OF　OLIGOPEPTIDES　RELATED　TO　GLUTATHIONE　FROM　PANAX　GINSENG

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Chinese Chemical Letters 1996年第4期7卷 337-340页

作者： chen, ZK Ye, yh.Xing, QY BEIJING UNIV DEPT CHEMBEIJING 100871PEOPLES R CHINA

Oligopeptides related to oxidized glutathione were isolated from aqueous methanol extract of Panax ginseng, through successive column chromatography on ion-exchange, gel-filtration and HPLC. Their structures had been identified with the methods of amino acid component analysis, N-terminal, C-terminal analysis and sequellce analysis.

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NONLINEAR DYNAMICS IN THE SOL-GEL PROCESS

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Chinese Chemical Letters 1995年第7期6卷 621-624页

作者： chen, yh.Guo, GL Tang, YC Zhai, C Beijing Univ Dept Chem Beijing 100871 Peoples R China

Si-29 NMR is used to measure the concentration of the various functional groups in an acid catalyzed Si(OEt)(4): EtOH: H2O sol-gel systems. The corresponding rate expressions for the reactions are shown in equations (1-3). The non-linear dynamics in the sol-gel process has been discussed. The molecular structure is changeable as the reactions proceed and the diffusion of clusters is spatially constrained. These factors lead to an anomalous kinetics. The overall rate coefficients have been got from numerical solution.

关键词： SOL NONLINEAR DYNAMICS IN THE SOL-GEL PROCESS

On the Methods of Beam Direction and MisorientationAngle/Axis Determination by Systematic Tilt

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Journal of Materials Science & Technology 1999年第5期15卷 410-414页

作者： Rong, yh.He, G chen, SP Hu, GX Gao, M Wei, RP Shanghai Jiao Tong Univ Sch Mat Sci & Engn Shanghai 200030 Peoples R China Lehigh Univ Dept Mech Engn & Mech Bethlehem PA 18015 USA

The methods for determining electron beam direction and misorientation angle/axis of grain boundaries are described in this paper. The present methods are based on a series of diffraction spot patterns obtained by systematic tilt of the crystal, combined with simple mathematical calculations. Instead of the use of Kikuchi patterns, the limitations resulting from the visibility or sharpness of Kikuchi lines and the number of Kikuchi pole(s) existed are avoided and a sufficient accuracy of determination has been achieved.

关键词： Transmission electron microscopy

Overexpression of low-density lipoprotein receptor prevents neurotoxic polarization of astrocytes via inhibiting NLRP3 inflammasome activation in experimental ischemic stroke

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Neural Regeneration Research 2025年第2期20卷 491-502页

作者： Shuai Feng Juanji Li Tingting Liu Shiqi Huang Xiangliang chen Shen Liu Junshan Zhou Hongdong Zhao Ye Hong Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Jinling HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina

Neurotoxic astrocytes are a promising therapeutic target for the attenuation of cerebral ischemia/reperfusion ***-density lipoprotein receptor,a classic cholesterol regulatory receptor,has been found to inhibit NLR family pyrin domain containing protein 3(NLRP3)inflammasome activation in neurons following ischemic stroke and to suppress the activation of microglia and astrocytes in individuals with Alzheimer’s ***,little is known about the effects of low-density lipoprotein receptor on astrocytic activation in ischemic *** address this issue in the present study,we examined the mechanisms by which low-density lipoprotein receptor regulates astrocytic polarization in ischemic stroke ***,we examined low-density lipoprotein receptor expression in astrocytes via immunofluorescence staining and western blotting *** observed significant downregulation of low-density lipoprotein receptor following middle cerebral artery occlusion reperfusion and oxygen-glucose deprivation/***,we induced the astrocyte-specific overexpression of low-density lipoprotein receptor using astrocyte-specific adeno-associated ***-density lipoprotein receptor overexpression in astrocytes improved neurological outcomes in middle cerebral artery occlusion mice and reversed neurotoxic astrocytes to create a neuroprotective ***,we found that the overexpression of low-density lipoprotein receptor inhibited NLRP3 inflammasome activation in oxygen-glucose deprivation/reoxygenation injured astrocytes and that the addition of nigericin,an NLRP3 agonist,restored the neurotoxic astrocyte *** findings suggest that low-density lipoprotein receptor could inhibit the NLRP3-meidiated neurotoxic polarization of astrocytes and that increasing low-density lipoprotein receptor in astrocytes might represent a novel strategy for treating cerebral ischemic stroke.

关键词： inflammation ischemia/reperfusion injury ischemic stroke low-density lipoprotein receptor neuroprotective astrocytes neurotoxic astrocytes NLRP3 inflammasome polarization

SYNTHESIS　OF　LINEAR　CONJUGATED　POLYBENZONITRILE　WITH　ULTRAFAST　OPTICAL　KERR　EFFECT

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Chinese Chemical Letters 1996年第1期7卷 71-72页

作者： Zhao, XY Xu, Q He, YK chen, HY Qiang, D Wang, CF Ai, XC Xia, ZJ Zou, yh BEIJING UNIV DEPT CHEMDIV POLYMERBEIJING 100871PEOPLES R CHINA BEIJING UNIV INST PHYS CHEMBEIJING 100871PEOPLES R CHINA BEIJING UNIV DEPT PHYSMESOSCOP PHYS LABBEIJING 100871PEOPLES R CHINA

Linear polybenzonitrile with carbon-nitrogen conjugated backbones was prepared by plasma polyemrization techniques The 'ultrafast Kerr effect of polymer in DMF solution was examined with femtosecond laser pulses Sec...

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Effect of pulley integrity on excursions and work of flexion in healing flexor tendons

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南通大学学报(医学版) 2003年第1期 116-117页

作者： Wang yh.Gu YT chen F

We investigated the effect of incision of a single critical pulley on excursions and work of flexion in healing flexor ***-two long toes from 21 white leghorn chickens were used as the experimental *** excursions of the flexor digitorum profundus tendons and work of flexion of the long toes were studied 8 weeks after tendon repair to determine the functions of the healed tendons in intact,incised, or enlarged A2 *** additional chickens (22 long toes) were used to obtain tendon excursion measurements in normal chicken *** 8 weeks,gliding excursions were statistically smaller in the intact pulley group than in the incised or enlarged pulley groups;the excursions were 73%+/-4% for the intact pulley group,88%+/-9% for the incised pulley group,and 91%+/-8% for the enlarged sheath group compared with the normal *** of flexion of the toes in the intact pulley group was statistically greater than that in the incised or enlarged pulley *** efficiency of the flexor tendons was not statistically different among the toes receiving different treatments in the *** results of this study demonstrate that release of a single pulley after repair of the tendons in this area improved gliding excursions of the tendons and reduced resistance to motion of the repaired tendons,and provide support for partial A2 pulley incision after repair of the tendons in the area of the pulley.(J Hand Surg 2001;26A:347-353,Copyright(C) 2001 by the American Society for Surgery of the Hand).

关键词： tendon sheath repair biomechanics hand

Intravitreal administration of bevacizumab in the treatment of choroidal metastasis in a patient with eriotinib-failed pulmonary adenocarcinoma.6

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Intravitreal administration of bevacizumab in the treatment ...