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纯银光亮退火工艺优化

特种铸造及有色合金 2024年第1期44卷 141-144页

作者：卢焕洵袁军平陈绍兴潘成强徐楚君陈惠昕广州番禺职业技术学院珠宝学院广州511483

光亮纯银首饰坯件在中间退火时常出现哑光,增加后续抛光工作量。以首饰行业常用纯银为原料,研究了光亮银条在大气下的退火工艺。结果表明,随着退火时间延长,硬度快速降低并逐渐趋缓;色差不断加大,且呈现先快后慢的趋势。随着加热温度提... 详细信息

光亮纯银首饰坯件在中间退火时常出现哑光,增加后续抛光工作量。以首饰行业常用纯银为原料,研究了光亮银条在大气下的退火工艺。结果表明,随着退火时间延长,硬度快速降低并逐渐趋缓;色差不断加大,且呈现先快后慢的趋势。随着加热温度提高,硬度降低速度加快,且最终的硬度值低,而色差值相应增加。因此,光亮纯银在大气下退火时,硬度下降和颜色保持需做出适当的平衡。对于中等壁厚手镯用光亮银条,退火时将温度控制在400℃左右,保温时间约为60 min,可满足硬度降低和光亮度保持需要。

关键词：纯银光亮退火硬度色差

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电弧3D打印TC4钛合金的组织与性能研究

热加工工艺 2024年第8期53卷 98-103页

作者：冯帅彭勇陈绍兴刘祥奎宋新翔康承飞孔见南京理工大学材料科学与工程学院江苏南京210094

采用冷金属过渡(Cold metal transfer,CMT)焊接技术制备了TC4钛合金件,研究了TC4钛合金增材体的显微组织和力学性能。结果表明:TC4钛合金打印态的表面成形良好,电弧3D打印TC4钛合金高度方向宏观组织上为外延生长的粗大β柱状晶形态,组... 详细信息

采用冷金属过渡(Cold metal transfer,CMT)焊接技术制备了TC4钛合金件,研究了TC4钛合金增材体的显微组织和力学性能。结果表明:TC4钛合金打印态的表面成形良好,电弧3D打印TC4钛合金高度方向宏观组织上为外延生长的粗大β柱状晶形态,组织由α相和β相组成。增材体的顶部为针状马氏体区,中部为细小的层片状网篮组织,基材结合处主要由层片状组织、β相以及少量残余α'相组成。所制备的成形件硬度较基材的高,表层部分硬度最大。室温拉伸性能呈现出明显的各向异性,水平方向拉伸强度较高,沿增材高度方向的塑性较高。室温冲击韧度未呈现出明显的各向异性,Aku2均达到70 J/cm2。

关键词：电弧3D打印 TC4钛合金组织特征力学性能

SOME APPROACHES TO THE MAIN TYPES OF CHINESE ENDANGERED PLANTS

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Journal of Geographical Sciences 1991年第2期2卷 57-67页

作者： chen shaoxing Zhang Yuanzhen Wang Ning Beijing Natural History Museum

The authors divide the 388 species of endangered plants recorded in the first volume of China Plant Red Data Book into 7 types:*** fossils;*** relics;*** of only a small range;*** genus;*** important element of the fl... 详细信息

关键词： flora endangered plants endemics

食管癌放疗引起食管瘘的危险因素Meta分析

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当代医学 2024年第15期30卷 1-7页

作者：陈少兴杨小煌林艺娜林坤花李艺江福建医科大学附属漳州市医院肿瘤放疗科福建漳州363000 福建医科大学附属协和医院消化内科福建福州350000

目的系统评价食管癌患者放疗引起食管瘘的危险因素。方法检索PubMed、Embase、The Cochrane Library、中国期刊全文数据库(知网)、中国学术期刊数据库(万方)及维普资讯中文科技期刊数据库等发表的中文及英文文献,检索时间为数据库建立至... 详细信息

目的系统评价食管癌患者放疗引起食管瘘的危险因素。方法检索PubMed、Embase、The Cochrane Library、中国期刊全文数据库(知网)、中国学术期刊数据库(万方)及维普资讯中文科技期刊数据库等发表的中文及英文文献,检索时间为数据库建立至2022年2月,中文检索词为“食管癌”“放疗”“食管穿孔”“食管瘘”等,英文检索词为“esophagus cancer”“tracheoesophageal fistula”“esophagorespiratory fistula”“esophageal fistula”“esophageal perforation”“radiotherapy”“radiationtherapy”“chemoradiotherapy”等。由3名评价者对文献进行质量评价,纳入与食管癌患者放疗引起食管瘘危险因素有关的合格文献,采用stata 12.0 SE软件进行Meta分析。结果最终纳入文献10篇,共2342例食管癌患者。Meta分析结果显示,KPS评分<80分(OR=1.770,95%CI=1.040~3.020,P=0.035)、N3分期(OR=2.060,95%CI=1.150~3.170,P=0.016)、T4分期(OR=2.250,95%CI=2.010~2.530,P<0.001)、溃疡型食管癌(OR=2.670,95%CI=1.700~4.190,P<0.001)、有吸烟史(OR=1.410,95%CI=1.040~1.920,P=0.028)、食管狭窄(OR=2.830,95%CI=1.070~4.970,P<0.001)、再程放疗(OR=5.430,95%CI=3.300~8.950,P<0.001)是食管癌患者放疗引起食管瘘的危险因素。结论KPS评分<80分、N3分期、T4分期、溃疡型食管癌、吸烟史、食管狭窄、再程放疗是食管癌放疗引起食管瘘的危险因素,临床应高度警惕上述因素,制定相应的预防措施,改善患者预后。

关键词：食管癌放疗食管瘘 Meta分析

海绵Phyllospongia Foliascens中的双高Scalarane二倍半萜

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高等学校化学学报 1991年第11期12卷 1486-1487页

作者：符雄曾陇梅苏镜娱 chen shaoxing Snyder John K. 中山大学化学系广州510275 美国波士顿大学化学系

具有Scalarane碳架的二倍半萜以及C-20单甲基化或C-20和C-24双甲基化的Scalarane型高二倍半萜普遍存在于Dictyoceratida科海绵中,我们从同科海绵Phyllospongia foliascens中已分离及测定了5个结构新颖的双高二倍半萜,本文报道另外2个双... 详细信息

具有Scalarane碳架的二倍半萜以及C-20单甲基化或C-20和C-24双甲基化的Scalarane型高二倍半萜普遍存在于Dictyoceratida科海绵中,我们从同科海绵Phyllospongia foliascens中已分离及测定了5个结构新颖的双高二倍半萜,本文报道另外2个双高二倍半萜phyllohemiketal A(1)和B(2)的分离和结构测定。

关键词：海绵二倍半萜分离结构

Long-term in vivo chimeric cells tracking in non-human primate

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Protein & Cell 2024年第3期15卷 207-222页

作者： Junmo Wu Yu Kang Xiang Luo shaoxing Dai Yuxi Shi Zhuoyao Li Zengli Tang Zhenzhen chen Ran Zhu Pengpeng Yang Zifan Li Hong Wang Xinglong chen Ziyi Zhao Weizhi ji Yuyu Niu State Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China Yunnan Key Laboratory of Primate Biomedical Research Kunming 650500China Faculty of Life Science and Technology Kunming University of Science and TechnologyKunming 650500China

Non-human primates(NHPs)are increasingly used in preclinical trials to test the safety and efficacy of biotech-nology ***,given the ethical issues and costs associated with this model,it would be highly advantageous to use NHP cellular models in clinical ***,developing and maintaining the naive state of primate pluripotent stem cells(PSCs)remains difficult as does in vivo detection of PSCs,thus limiting biotech-nology application in the cynomolgus ***,we report a chemically defined,xeno-free culture system for culturing and deriving monkey PSCs in *** cells display global gene expression and genome-wide hypometh-ylation patterns distinct from monkey-primed *** also found expression of signaling pathways components that may increase the potential for chimera *** for biomedical applications,we were also able to integrate bioluminescent reporter genes into monkey PsCs and track them in chimeric embryos in vivo and in *** engineered cells retained embryonic and extra-embryonic developmental ***,we generated a chimeric monkey carrying bioluminescent cells,which were able to track chimeric cells for more than 2 years in living *** study could have broad utility in primate stem cell engineering and in utilizing chimeric monkey models forclinical studies.

关键词： pluripotent stem cells bioluminescence imaging non-human primates

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嗜盐古菌几种常见胞外酶研究进展

微生物学通报 2021年第3期48卷 830-841页

作者：王锐陈绍兴安徽师范大学生命科学学院安徽芜湖241000

嗜盐古菌是一类生活于极端高盐环境的化能异养型原核微生物,其所分泌的胞外酶(外泌酶)具有在高盐条件下仍能保持活性的特点,在制革工业、高盐有机废水处理和泡菜加工等腌制食品方面发挥重要用途。本文对嗜盐古菌的胞外蛋白酶、淀粉酶、... 详细信息

嗜盐古菌是一类生活于极端高盐环境的化能异养型原核微生物,其所分泌的胞外酶(外泌酶)具有在高盐条件下仍能保持活性的特点,在制革工业、高盐有机废水处理和泡菜加工等腌制食品方面发挥重要用途。本文对嗜盐古菌的胞外蛋白酶、淀粉酶、酯酶等几种常见胞外酶的来源和基本酶学性质的最新研究进展进行综述,为更好地开发利用嗜盐古菌胞外酶资源提供参考。

关键词：嗜盐古菌外泌酶蛋白酶淀粉酶酯酶

Halorubrum yunnanense ***.,isolated from Salt Ore Yipinglang,Yunnan,China

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Halorubrum yunnanense ***.,isolated from Salt Ore Yipinglang...

Integrative bioinformatics and in vitro exploration of EVI2A expression:unraveling its immunological and prognostic implications in kidney renal clear cell carcinoma

2008年中国微生物学会学术年会

作者： shaoxing chen (College of life sciences and technology,Honghe University,Mengzi 661100,Yunnan )

Strain YYJ21 was isolated from a ore sample collected from Salt Ore Yipinglang (25°15’ N,101°92’ E) in Yunnan,*** the sampling(September 2005) the Salt Ore area had a temperature between 15 to 21℃,an altitude of *** isolation procedure was as described by *** proposed minimal standards for the description of novel taxa were according to which Oren described in the order *** motility and morphology were examined by phase-contrast

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Oncology Research 2024年第11期32卷 1733-1746页

作者： RONG LIU SHENG LI SITU XIONG FUCUN ZHENG XIANGPENG ZHAN JIN ZENG BIN FU SONGHUI XU shaoxing ZHU RU chen Department of Urology Fujian Medical University Union HospitalFuzhou350000China Department of Urology The First Affiliated Hospital of Nanchang UniversityNanchang350000China

EVI2A has emerged as a significant biomarker in various diseases;however,its biological role and mechanism in kidney renal clear cell carcinoma(KIRC)remains *** used TCGA and GEO databases to analyze EVI2A gene expression comprehensively and performed pan-cancer *** relevance was evaluated through Kaplan-Meier analysis and ROC *** gene’s immune relevance was explored through analyses of the tumor microenvironment(TME),Tumor Immune Single-cell Hub(TISCH),immune checkpoints,and immunotherapy *** results indicate that EVI2A expression is upregulated in KIRC,showing correlations with tumor grade and T/N/M ***2A demonstrates high diagnostic accuracy(AUC=0.906)and predicts poor overall and progression-free survival in KIRC ***,EVI2A expression exhibits significant associations with immunity,including TME scores and specific immune cell types such as Tfh cells,CD4 memory T cells,and CD8+T *** EVI2A expression suggests increased sensitivity to PD-1/CTLA-4 and tyrosine kinase *** vitro assays confirmed the impact of EVI2A on KIRC behavior,with its knockdown resulting in reduced cell proliferation and *** conclusion,our comprehensive analysis identifies EVI2A as a promising biomarker and a novel therapeutic target for intervening in *** findings hold significant implications for further research and potential clinical applications.

关键词： EVI2A Kidney Renal Clear Cell Carcinoma(KIRC) Prognosis Immunological analysis