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Seeing at a distance with multicore fibers

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Opto-Electronic Advances 2024年第7期7卷 39-49页

作者： Haogong Feng Xi chen Runze Zhu Yifeng Xiong ye chen Yanqing Lu Fei Xu National Laboratory of Solid State Microstructures College of Engineering and Applied Sciencesand Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China College of Physics MIIT Key Laboratory of Aerospace Information Materials and PhysicsState Key Laboratory of Mechanics and Control for Aerospace StructuresNanjing University of Aeronautics and AstronauticsNanjing 211106China

Images and videos provide a wealth of information for people in production and *** most digital information is transmitted via optical fiber,the image acquisition and transmission processes still rely heavily on electronic *** development of all-optical transmission networks and optical computing frameworks has pointed to the direction for the next generation of data transmission and information ***,we propose a high-speed,low-cost,multiplexed parallel and one-piece all-fiber architecture for image acquisition,encoding,and transmission,called the Multicore Fiber Acquisition and Transmission Image System(MFAT).Based on different spatial and modal channels of the multicore fiber,fiber-coupled self-encoding,and digital aperture decoding technology,scenes can be observed directly from up to 1 km *** expansion of capacity provides the possibility of parallel coded transmission of multimodal high-quality *** requires no additional signal transmitting and receiving *** all-fiber processing saves the time traditionally spent on signal conversion and image pre-processing(compression,encoding,and modulation).Additionally,it provides an effective solution for 2D information acquisition and transmission tasks in extreme environments such as high temperatures and electromagnetic interference.

关键词： long-distance fiber imaging image transmission parallel transmission all-optical encoding multicore fiber

A cost-efficient quantum access network with qubit-based synchronization

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 12-22页

作者： Chunfeng Huang ye chen Tingting Luo Wenjie He Xin Liu Zhenrong Zhang Kejin Wei Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Guangxi Key Laboratory of Multimedia Communications and Network Technology School of Computer Electronics and InformationGuangxi UniversityNanning 530004China

Quantum key distribution(QKD)is a physical layer encryption technique that enables two distant parties to exchange secure keys with information-theoretic *** the last two decades,QKD has transitioned from laboratory research to real-world applications,including multi-user quantum access networks(QANs).This network structure allows users to share a single-photon detector at a network node through time-division multiplexing,thereby significantly reducing the network ***,current QAN implementations require additional hardware for auxiliary tasks such as time *** address this issue,we propose a cost-efficient QAN that uses qubit-based *** this approach,the transmitted qubits facilitate time synchronization,eliminating the need for additional synchronization *** tested our scheme by implementing a network for two users and successfully achieved average secure key rates of 53.84 kbps and 71.90 kbps for each user over a 50-km commercial fiber *** addition,we investigated the capacity of the access network under cross-talk and loss *** simulation results demonstrate that this scheme can support a QAN with 64 users with key rates up to 1070 *** work provides a feasible and cost-effective way to implement a multi-user QKD network,further promoting the widespread application of QKD.

关键词： quantum key distribution quantum access network qubit-based synchronization

Evaluation and salivary biochemistry associations of sour-salty taste interaction

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Journal of Future Foods 2024年第4期4卷 376-382页

作者： Hongnan Jiang ye chen Jianshe chen Louise Dye Xinmiao Wang Laboratory of Food Oral Processing School of Food Science and BiotechnologyZhejiang Gongshang UniversityHangzhou 310018China Zhejiang-UK Joint Laboratory of Food Sensory Science Zhejiang Gongshang UniversityHangzhou 310018China School of Food Science and Nutrition University of LeedsLeeds LS29JTUK

Taste interaction is a well-known phenomenon in sensory stodies,but how to quantify the magnitode of the effect of one tastant on other taste attribute(s)is still largely unsolved,let alone further explorations from a salivary biochemistry *** acquiring the individual taste threshold and evaluating the just noticeable difference(JND).this stody firstly established a quantitative method to assess the magnitude of taste interaction in a binary taste mixture by evaluating the concentration difference upon psychologically-comparable *** change of salty taste intensity(CSI)was therefore defined as the subtraction of JND using sour-salty taste stimulant from JND using pure salty taste stimulant,with a dimension of concentration in mmol/*** was then used to demonstrate how citric acid affected salty taste perception in a salty-sour binary taste mixture in 16 young and healthy *** of citric acid used in the binary taste mixtore were 0.***.0.09.0.***.0.24 and 0.40 mmolL,*** results showed that salty taste perception was enhanced(average CSI of 0.93 mmolL)when the citric acid concentration was low(at 0.05 and 0.09 mmolL).but with an increasing concentration of citric acid ranging from 0.14 to 0.40 mmol/L,this effect gradually turned from enhancement to suppression of salty taste perception(correspondingly a continoously decreasing CSI all the way down to an average of-2.94 mumol/L).It was also found that cystatin SN concentration in participants'unstimulated saliva samples was significantly negatively correlated with salty taste threshold(with and without the presence of citric acid),and it was one of the most significant factors affecting CSI,s shown in multiple regression *** anhydrase VI concentration in participants'unstimulated saliva sanples was also found to be significantly negatively correlated with salty taste recognition(with and without presence of citric acid).but it did not pose signific

关键词： Taste interaction evaluation Sensory analysis Salty taste perception Salivay biochemical components

The RFI Fast Mitigation Algorithm Based on Block LMS Filter

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Research in Astronomy and Astrophysics 2024年第1期24卷 265-272页

作者： Han Wu Hai-Long Zhang Ya-Zhou Zhang Jie Wang Xu Du Ting Zhang Xin-chen ye Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China National Astronomical Data Center Beijing 100101China

The radio telescope possesses high sensitivity and strong signal collection *** receiving celestial radiation signals,it also captures Radio Frequency Interferences(RFIs)introduced by human ***,as signals originating from sources other than the astronomical targets,significantly impacts the quality of astronomical *** paper presents an RFI fast mitigation algorithm based on block Least Mean Square(LMS)*** enhances the traditional adaptive LMS filter by grouping L adjacent time-sampled points into one block and applying the same filter coefficients for filtering within each *** transformation reduces multiplication calculations and enhances algorithm efficiency by leveraging the time-domain convolution *** algorithm is tested using baseband data from the Parkes 64 m radio telescope's pulsar observations and simulated *** results confirm the algorithm's effectiveness,as the pulsar profile after RFI mitigation closely matches the original pulsar profile.

关键词： methods:data analysis techniques:interferometric (stars:)pulsars:individual(J0437-4715)

Success of susceptibility-guided eradication of Helicobacter pylori in a region with high secondary clarithromycin and levofloxacin resistance rates

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World Journal of Gastroenterology 2024年第2期30卷 184-195页

作者： Yan-Meng Wang Mo-ye chen Jing chen Xin-He Zhang Yan Feng Yu-Xi Han Yi-Ling Li Department of Gastroenterology The First Affiliated Hospital of China Medical UniversityShenyang 110000Liaoning ProvinceChina Key Laboratory of Cancer Etiology and Prevention in Liaoning Education Department The First Hospital of China Medical UniversityShenyang 110000Liaoning ProvinceChina

BACKGROUND Resistance to clarithromycin(CLA)and levofloxacin(LFX)of Helicobacter pylori(***)is increasing in severity,and successful eradication is ***,the eradication success rate has greatly declined,leaving a large number of patients with previous treatment *** To investigate secondary resistance rates,explore risk factors for antibiotic resistance,and assess the efficacy of susceptibility-guided *** We recruited 154 subjects positive for Urea Breath Test who attended The First Affiliated Hospital of China Medical University between July 2022 and April *** underwent a string test after an overnight *** gastric juice was obtained and transferred to vials containing storage ***,DNA extraction and the specific DNA amplification were performed using quantitative polymerase chain reaction(qPCR).Demographic information was also analyzed as part of the *** on these results,the participants were administered susceptibility-guided *** was compared with that of the empiric treatment *** A total of 132 individuals tested positive for the *** ureA gene by qPCR *** resistance rate reached a high level of 82.6%(n=109),LFX resistance rate was 69.7%(n=92)and dual resistance was 62.1%(n=82).Gastric symptoms[odds ratio(OR)=2.782;95%confidence interval(95%CI):1.076-7.194;P=0.035]and rural residence(OR=5.152;95%CI:1.407-18.861;P=0.013)were independent risk factors for secondary resistance to CLA and LFX,respectively.A total of 102 and 100 individuals received susceptibility-guided therapies and empiric treatment,*** antibiotic susceptibility-guided treatment and empiric treatment groups achieved successful eradication rates of 75.5%(77/102)and 59.0%(59/411)by the intention-to-treat(ITT)analysis and 90.6%(77/85)and 70.2%(59/84)by the per-protocol(PP)analysis,*** eradication rates of these two treatment strategies were significantly

关键词： Helicobacter pylori Antibiotic resistance Clarithromycin Levofloxacin String-test Susceptibility-guided therapy Eradication rate

Dynamic failure process of expanded polystyrene particle lightweight soil under cyclic loading using discrete element method

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Earthquake Engineering and Engineering Vibration 2024年第4期23卷 815-828页

作者： Zhou Wei Hou Tianshun chen ye Wang Qi Luo Yasheng Zhang Yafei College of Water Resources and Architectural Engineering Northwest A&F UniversityXianyang 712100China Xi’an Key Laboratory of Geotechnical and Underground Engineering Xi’an University of Science and TechnologyXi’an 710054China Hanjiang to Weihe River Valley Water Diversion Project Construction Co. Ltd.Xi’an 710011China

Expanded polystyrene(EPS)particle-based lightweight soil,which is a type of lightweight filler,is mainly used in road *** stability of subgrades under dynamic loading is attracting increased research *** traditional method for studying the dynamic strength characteristics of soils is dynamic triaxial testing,and the discrete element simulation of lightweight soils under cyclic load has rarely been *** study the meso-mechanisms of the dynamic failure processes of EPS particle lightweight soils,a discrete element numerical model is established using the particle flow code(PFC)*** contact force,displacement field,and velocity field of lightweight soil under different cumulative compressive strains are *** results show that the hysteresis curves of lightweight soil present characteristics of strain accumulation,which reflect the cyclic effects of the dynamic *** the confining pressure increases,the contact force of the particles also *** confining pressure can restrain the motion of the particle system and increase the dynamic strength of the *** the confining pressure is held constant,an increase in compressive strain causes minimal change in the contact force between soil ***,the contact force between the EPS particles decreases,and their displacement direction points vertically toward the center of the *** an increase in compressive strain,the velocity direction of the particle system changes from a random distribution and points vertically toward the center of the *** the compressive strain is 5%,the number of particles deflected in the particle velocity direction increases significantly,and the cumulative rate of deformation in the lightweight soil ***,it is feasible to use 5%compressive strain as the dynamic strength standard for lightweight *** element methods provide a new approach toward the dynamic performance evaluation of lightw

关键词： lightweight soil cyclic loading dynamic triaxial test discrete element method hysteresis curve

DNA framework signal amplification platform-based highthroughput systemic immune monitoring

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1115-1131页

作者： ye chen Xingyu chen Bowen Zhang Yuxin Zhang Songhang Li Zhiqiang Liu Yang Gao Yuxuan Zhao Lin Yan Yi Li Taoran Tian Yunfeng Lin State Key Laboratory of Oral Diseases National Center for StomatologyNational Clinical Research Center for Oral DiseasesWest China Hospital of StomatologySichuan UniversityChengdu 610041 SichuanPR China Department of Prosthodontics Tianjin Stomatological HospitalSchool of MedicineNankai UniversityTianjin 300041PR China Department of Laboratory Medicine West China HospitalSichuan UniversityChengdu 610041 SichuanPR China Sichuan Provincial Engineering Research Center of Oral Biomaterials Chengdu 610041 SichuanChina

Systemic immune monitoring is a crucial clinical tool for disease early diagnosis,prognosis and treatment planning by quantitative analysis of immune ***,conventional immune monitoring using flow cytometry faces huge challenges in large-scale sample testing,especially in mass health screenings,because of time-consuming,technical-sensitive and high-cost ***,the lack of high-performance detection platforms hinders the development of high-throughput immune monitoring *** address this bottleneck,we constructed a generally applicable DNA framework signal amplification platform(DSAP)based on post-systematic evolution of ligands by exponential enrichment and DNA tetrahedral framework-structured probe design to achieve high-sensitive detection for diverse immune cells,including CD4+,CD8+T-lymphocytes,and monocytes(down to 1/100μl).Based on this advanced detection platform,we present a novel high-throughput immune-cell phenotyping system,DSAP,achieving 30-min one-step immune-cell phenotyping without cell washing and subset analysis and showing comparable accuracy with flow cytometry while significantly reducing detection time and *** a proof-of-concept,DSAP demonstrates excellent diagnostic accuracy in immunodeficiency staging for 107 HIV patients(AUC>0.97)within 30 min,which can be applied in HIV infection monitoring and ***,we initially introduced promising DSAP to achieve high-throughput immune monitoring and open robust routes for point-of-care device development.

关键词： diagnosis monitoring initially

Profile of Dr. ye-Guang chen

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Science China(Life Sciences) 2018年第7期61卷 799-799页

作者： chen ye-Guang

***-Guang chen graduated from Jiangxi University with BSc in biology in 1983,earned master’s degrees at Jiangxi University in zoology in 1986 and at Fordham University,New York in cell biology in 1990,and was awarded Ph D by Albert Einstein College of Medicine,New York in cell biology in *** the postdoc training at Memorial Sloan-Kettering Cancer Center/Howard Hughes Medical Institute,New York,he was recruited to University of California,Riverside as assistant professor in *** moved to Tsinghua University as a professor in 2002.

关键词：加利福尼亚大学侧面博士生物学同步通信硕士学位爱因斯坦二进制

Lutein-stevioside nanoparticle attenuates H_(2)O_(2)-induced oxidative damage in ARPE cells

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Food Science and Human Wellness 2024年第3期13卷 1628-1635页

作者： Zhuqing Dai Meimei Nie ye chen Jiangfeng Song Yayuan Xu Zhongyuan Zhang Guodong Zhang Shumo Yan Xing Zhang Dajing Li Institute of Agro-Product Processing Jiangsu Academy of Agricultural SciencesNanjing 210014China Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base Ministry of Science and TechnologyNanjing 210014China Jiangsu Aland Nutrition Co. Ltd.Taizhou 214500China Aland Nutrition Taizhou Co. Ltd.Taizhou 225300China

In order to improve the bioavailability of lutein(LUT),a novel lutein-stevio side nanoparticle(LUT-STE)were prepared previously,but the information about LUT-STE on protecting of eye health was *** study investigated the effect of LUT-STE on antioxidant activity of H_(2)O_(2)-induced human retinal pigment epithelial(ARPE)*** and LUT-STE(final concentration of 5μg/mL)significantly enhanced cell viability from(74.84±5.10)%to(81.92±10.01)%(LUT)and(89.33±4.34)%(LUT-STE),and inhibited the cell apoptosis(P<0.05).After pretreatment with LUT-STE in ARPE cells,the levels of superoxide dismutase(SOD),catalase(CAT)and glutathion peroxidase(GSH-Px)in ARPE cells were significantly increased(P<0.05),the contents of reactive oxygen species(ROS)and malondialdehyde(MDA)were *** addition,the vascular endothelial growth factor(VEGF)levels were inhibited by 13.61%and 17.39%,respectively,pretreatment with LUT and *** blotting results showed that the pretreatment with LUT-STE inhibited the expression of caspase-9 and caspase-3 and up-regulated Bcl-2/Bax pathway to inhibit H_(2)O_(2)-induced *** summary,the novel delivery LUT-STE had more pronounced inhibitory effect on H_(2)O_(2)-induced damage in human ARPE cells.

关键词： Lutein Stevioside Antioxidant Human retinal pigment epithelial cell Mechanism