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Early hemodynamics after tibial transverse transport in patients with nonarterial stenosis and arterial stenosis diabetic foot

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World Journal of Diabetes 2023年第12期14卷 1784-1792页

作者： Mei-Mei Liao sen chen Jia-Rui Cao Meng-Wei Wang Zhi-Hui Jin Jia Ye Yi-Jun Ren Rui-Qiang Guo Department of Ultrasound Imaging Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina Department of Orthopedics Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina

BACKGROUND The diagnosis of peripheral arteriopathy in the diabetic foot is complicated by diabetes and its advanced *** has been found that diabetic foot can be categorized into arterial stenosis and non-arterial stenosis,both of which have significant differences in hemodynamic *** To evaluate the early hemodynamic changes in diabetic foot patients with nonarterial stenosis and arterial stenosis treated by tibial transverse transport(TTT)using high-frequency color Doppler ultrasonography(HFCDU)and a laser Doppler *** Twenty-five patients with Wagner grades 3-5 diabetic foot ulcers were treated with TTT,and the wound healing time and rate were *** were grouped according to the results of preoperative lower-extremity *** with≥50%stenosis in any of the femoral,popliteal,posterior tibial,anterior tibial,and peroneal arteries of the affected limb were classified as the arterial stenosis group(n=16);otherwise,they were classified as the nonarterial stenosis group(n=9).Before and one month after surgery,HFCDU was used to evaluate the degree of lower limb artery lesions and hemodynamic changes in *** degree of femoral-popliteal atherosclerotic stenosis,the degree of vascular stenosis and occlusion of the lower-knee outflow tract,and the degree of medial arterial calcification were scored;the three scores were added together to obtain the total score of lower extremity ***3,a laser Doppler flowmeter system,was used to detect alterations in plantar microcirculation before and 1 mo after *** healing and hemodynamic indices were compared between the two *** The wound healing time of the diabetic foot was significantly shorter in the nonarterial stenosis group than in the arterial stenosis group(47.8±13 vs 85.8±26,P<0.05),and the wound healing rate of both groups was 100%.The preoperative total lower extremity arteriopathy scores were lower in the nonar

关键词： High-frequency color Doppler ultrasonography Diabetic foot Tibial transverse transport Nonarterial stenosis Arterial stenosis

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基于一类因果关系图的综合评价方法及应用

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控制与决策 2010年第10期25卷 1513-1518页

作者：何宽陈森发东南大学经济管理学院南京210096

首先运用数据处理组合法对区域循环经济发展进行均衡分析;然后借助格兰杰因果关系的思想,将均衡分析的结果转换为一类因果关系图,并定义了此图的节点信息控制强度和受控信息强度,进而确定指标权重,完成区域循环经济发展的综合评价.评价... 详细信息

首先运用数据处理组合法对区域循环经济发展进行均衡分析;然后借助格兰杰因果关系的思想,将均衡分析的结果转换为一类因果关系图,并定义了此图的节点信息控制强度和受控信息强度,进而确定指标权重,完成区域循环经济发展的综合评价.评价结果数值显示,基于一类因果关系图的综合评价方法稳定可靠,是可解释的.

关键词：综合评价权重因果关系图区域循环经济

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Effect of stellate block on vasomotor factor, vascular endothelial nitricoxide synthase and pulmonary arterial pressure in rabbits with hypoxic pulmonary artery hypertension

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Neural Regeneration Research 2007年第3期2卷 129-133页

作者： Shunhou He Qing Li sen chen Qingxiu Wang Department of Anesthesiology Taihe Hospital Affiliated to Yunyang Medical College Shiyan 442000 Hubei Province China Department of Anesthesiology Shiyan Obstetric and Gynecology Hospital Shiyan 442000 Hubei Province China Department of Anesthesiology People＇s Hospital Affiliated to Yunyang Medical College Shiyan 442000 Hubei Province China

BACKGROUND： At present, inhalation of nitrogen monoxidum （NO） or other angiotenic is widely used to cure hypoxic pulmonary artery hypertension. In addition, recent researches demonstrate that postganglionic fiber of stellate ganglion can regulate contents of blood vessel endothelium-calcitonin gene-related peptide （BVE-CGRP） and nitricoxide synthase （NOS） in lung tissue. Therefore, stellate ganglion which is blocked with the local anesthetic may cause therapeutic effects on hypoxic pulmonary artery hypertension. OBJECTIVE： To observe the effects of stellate block on calcitonin gene-related peptide （CGRP） of vasodilation factors, prostacyclin, endothelin-i of vasoconstriction factors, thromboxan, blood vessel endothelium-nitricoxide synthase （BVE-NOS） and mean arterial pressure of lung tissue in rabbits with hypoxic pulmonary artery hypertension. DESIGN： Randomly controlled animal study. SETTING： Neurological Institute of Taihe Hospital Affiliated to Yunyang Medical College. MATERIALS： A total of 24 adult Japanese rabbits of both genders and weighing 2.3 - 2.6 kg were provided by Animal Experimental Center of Hubei Academy of Medical Science. SP kit was provided by Beijing Zhongshan Biotechnology Co., Ltd.; moreover, kits of endothelin-1, CGRP, prostacyclin and thromboxan were provided by Radioimmunity Institute, Scientific and Technological Developing Center, General Hospital of Chinese PLA, and color image analytical system （Leica-Q500IW） was made in Germany. METHODS：The experiment was carried out in the Neurological Institute of Taihe Hospital affiliated to Yunyang Medical College from February to December 2002. ① Rabbits were performed with aseptic manipulation to exposure left stellate ganglion and then it was put in epidural catheter for 1 week. In addition, one end of epidural catheter was fixed near by stellate ganglion and the other end was fixed through dorsal neck. All rabbits were randomly divided into 4 groups, including normal control group, stellate bl

关键词： stellate ganglion anoxia hypertension, pulmonary calcitonin gene-related peptide nitric-oxide synthase

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Return threshold model analysis of two stock markets： Evidence study of Italy and Germany＇s stock returns

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Chinese Business Review 2010年第1期9卷 23-35页

作者： Wann-Jyi Horng Yu-cheng chen Weir-sen Lin Department of Hospital and Health Care Administration Chia Nan University of Pharmacy and Science Tainan 71710 Taiwan

This paper discusses the model construction and the association between the Italy and the Germany＇s stock markets. The period of study data is from January 3, 2000 to June 30, 2008. This paper also utilizes Student＇s t distribution to analyze the proposed model. The empirical results show that the two stock markets are mutually affected each other, and the dynamic conditional correlation （DCC） and the bivariate asymmetric-GARCH （1, 2） model is appropriate in evaluating the relation between them. The empirical result also indicates that Italy and Germany＇s stock markets show a positive relationship. The average value of correlation coefficient equals to 0.8424, which implies that the two stock markets return volatility have a synchronized influence on each other. In addition, the empirical result also shows that there is an asymmetrical effect between Italy and the Germany＇s stock markets, and demonstrates that the good news and bad news of the stock returns＇ volatility will produce the different variation risks for Italy and the Germany＇s stock price markets.

关键词： stock market returns GARCH model asymmetric effect GJR-GARCH model bivariate asymmetric GARCH model

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Auxin regulates anthocyanin biosynthesis through the Aux/IAA–ARF signaling pathway in apple

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Horticulture Research 2018年第1期5卷 43-53页

作者： Yi-cheng Wang Nan Wang Hai-feng Xu Sheng-hui Jiang Hong-cheng Fang Meng-yu Su Zong-ying Zhang Tian-liang Zhang Xue-sen chen State Key Laboratory of Crop Biology College of Horticulture Science and EngineeringShandong Agricultural UniversityTai-AnShandongChina Collaborative Innovation Center of Fruit&Vegetable Quality and Efficient Production in Shandong Tai-AnShandongChina

Auxin signaling,which is crucial for normal plant growth and development,mainly depends on ARF–Aux/IAA ***,little is known regarding the regulatory effects of auxin signaling on anthocyanin metabolism in apple(Malus domestica).We investigated the functions of MdARF13,which contains a repression domain and is localized to the *** protein was observed to interact with the Aux/IAA repressor,MdIAA121,through its C-terminal dimerization *** degradation experiments proved that MdIAA121 is an unstable protein that is degraded by the 26S ***,MdIAA121 stability is affected by the application of exogenous ***,the overexpression of MdIAA121 and MdARF13 in transgenic red-fleshed apple calli weakened the inhibitory effect of MdARF13 on anthocyanin *** results indicate that the degradation of MdIAA121 induced by auxin treatment can release MdARF13,which acts as a negative regulator of the anthocyanin metabolic ***,yeast two-hybrid,bimolecular fluorescence complementation,and pull-down assays confirmed that MdMYB10 interacts with MdARF13.A subsequent electrophoretic mobility shift assay and yeast one-hybrid assay demonstrated that MdARF13 directly binds to the promoter of MdDFR,which is an anthocyanin pathway structural ***,chromatin immunoprecipitation–quantitative real-time PCR results indicated that the overexpression of MdIAA121 clearly inhibits the recruitment of MdARF13 to the MdDFR *** findings further characterized the mechanism underlying the regulation of anthocyanin biosynthesis via Aux/IAA–ARF signaling.

关键词： Aux/IAA metabolism anthocyanin

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The CAD/CAM Solution and Realization for Machining Large Scale Steel-concrete Objects

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厦门大学学报（自然科学版） 2002年第S1期41卷 14-15页

作者： ZHENG Yong-qian, chen Bing-sen, ZHANG Wei-min, FAN Liu-qun (Department of Mechanical Engineering, Tongji University, Shanghai 200092, China)

First the architecture of the integrated CAD/CAM system developed for machining large scale steel-concrete girders using I-DEAS and other developing tools are introduced; then the involved technologies in the development of the system are presented, which include the method for determining the position and orientation of the manufacturing features, the method for geometrical modeling of the girders, the techniques for generating the toolpaths for the 5-axis machining centers, the generative process planning technique and the postprocssing technique for the specific machines etc. Moreover some related special technical issues are also discussed. The CAD/CAM system is a network-based workshop-oriented manufacturing system, in which every machining cell can work independently serving two machining lines. The cell server take charge of the management of work schedules, personnel, machining resources, databases etc. the control computer serves to monitor the whole manufacturing lines, to arrange tasks, and to communicate; the two CAD/CAM workstations’ work is to model the girders using the CAD data, to plan the process and to generate the NC programs. The CL files that describe the toolpaths generated are ATP-format files. In order to translate them into NC codes that can be directly used by the 5-axis machining centers, a specific postprocessing program is developed for these distinct machines. The system has been successfully realized and applied in Shanghai Maglev Transrapid project. In the developing process, the following technical problems are solved: 1. Algorithms for measuring, positioning, and machining complex objects. 2. Methods for Modeling. 3. Animation and postprocess techniques for 5-axis machining centers. 4. Technologies for machining large-scale concrete-steel structures Although further evolution is needed for this system, the facts have proven its performance satisfactory and the technologies and the methods developed suitable.

关键词： maglev transrapid CAD/CAM manufacturing feature Pseudo-NC Real-NC post process

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加权马尔可夫SCGM(1,1)_c模型在农作物干旱受灾面积预测中的应用

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系统工程理论与实践 2009年第9期29卷 179-185页

作者：姜翔程陈森发东南大学系统工程研究所南京210096 河海大学水利经济研究所南京210098

基于灰色系统理论和马尔可夫链原理,应用系统云灰色模型拟合时序数据的总体趋势,所得拟合精度指标是随机波动的,而马尔科夫链原理适合处理波动性大的系统过程,选用能更好解决随机波动性的加权马尔可夫链预测方法,提出一种用于农作物干... 详细信息

基于灰色系统理论和马尔可夫链原理,应用系统云灰色模型拟合时序数据的总体趋势,所得拟合精度指标是随机波动的,而马尔科夫链原理适合处理波动性大的系统过程,选用能更好解决随机波动性的加权马尔可夫链预测方法,提出一种用于农作物干旱受灾面积预测的加权马尔可夫SCGM(1,1)c模型,适用时间短、数据量少且随机波动大的动态过程预测.以我国农作物干旱受灾面积预测为例,表明加权马尔可夫SCGM(1,1)c模型对于农业旱灾预测具有较高的精度.

关键词：单因子系统云灰色模型加权马尔可夫链干旱受灾面积预测

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江藩《漢學師承記》纂著史實索隱

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文史 2019年第3期 147-178页

作者：陳鴻森臺灣“中研院”歷史語言研究所蘇州大學文學院

江藩《漢學師承記》係一紀傳體的斷代學術史,江氏以傳記形式,將清嘉慶中葉以前具代表性的“漢學”者彙爲一編,每傳各記其生平事迹、師承交游、著作情況,以及主要學術創見等,藉以呈現清代“漢學”發皇、流衍的概況。本文主要目的,一則考... 详细信息

江藩《漢學師承記》係一紀傳體的斷代學術史,江氏以傳記形式,將清嘉慶中葉以前具代表性的“漢學”者彙爲一編,每傳各記其生平事迹、師承交游、著作情況,以及主要學術創見等,藉以呈現清代“漢學”發皇、流衍的概況。本文主要目的,一則考證《漢學師承記》的纂輯年代,並揭示江藩纂著此書隱微的心曲;次則分析江藩的纂著意圖和成書背景,並探討其書與阮元纂修《儒林傳》的關係;三則考證江藩刻意將黄宗羲、顧炎武二傳編列卷末的隱衷等數事,鈎沈索隱,提出新的論述,並對現行諸説提出商榷,以備知人論世之義。

关键词：江藩《漢學師承記》阮元《儒林傳稿》乾嘉學術

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Relationship Between Anthocyanin Biosynthesis and Related Enzymes Activity in Pyrus pyrifolia Mantianhong and Its Bud Sports Aoguan

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Agricultural Sciences in China 2008年第11期7卷 1318-1323页

作者： FENG Shou-qian chen Xue-sen ZHANG Chun-yu LIU Xiao-jing LIU Zun-chun WANG Hai-bo WANG Yan-ling ZHOU Chao-hua State Key Laboratory of Crop Biology Shandong Agricultural University Tai＇an 271018 P.R. China Henan Institute of Science and Technology Xinxiang 453003 P.R.China Liaocheng Forestry Bureau Liaoeheng 252000 P.R.China

The aim of this article is to study the relationship between biosynthesis of anthocyanin and activities of phenylalanine ammonia lyase （PAL）, chalcone ismoerase （CHI） enzymes in Pyrus pyrifolia. Changes in the level of anthocyanin and the activities of enzymes of anthocyanin biosynthesis including PAL, CHI were studied in the pericarp of Pyrus pyrifolia Aoguan and Mantianhong during the period of pigment formation. Bagging treatment was also carried out to manipulate the synthesis of anthocyanin and the activities of related enzymes during the period of pigment formation. The results demonstrated that the level of anthocyanin of Aoguan was higher than that of Mantianhong. However, the content of anthocyanins has the similar changing trend in Aoguan and Mantianhong, highest anthocyanin concentrations of two varieties appeared in immature fruit and faded toward harvest. Meanwhile, similar changing trends of activities of PAL and CHI were also observed in both varieties. Aoguan has a lower activity of PAL than Mantianhong, whereas activity of CHI in Aoguan was higher than that in Mantianhong. Activity of PAL decreased during the period of pigment formation and was apparently not limiting to color development, whereas CHI activity increased at the same period and was closely related to the synthesis of anthocyanin. The results of bagging treatment showed that bagging treatment inhibited the activity of CHI, as well as the synthesis of anthocyanin, whereas debagging enhanced both the activity of CHI and synthesis of anthocyanin. The activity of CHI in debagging Aoguan pericarp was higher than the untreated Aoguan. However, effect of bagging treatment toward PAL activity was not obvious. Anthocyanin of bagging treated Aoguan decreased toward harvest. The content of anthocyanin of Pyruspyrifolia increased at the beginning of fruit coloration period and decreased toward fruit harvest. Activity of PAL was apparently not limiting to color development, whereas CHI activity was

关键词： Pyrus pyrifolia anthocyanin PAL CHI

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马宗琏行年考

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复旦学报（社会科学版） 2015年第5期57卷 71-84页

作者：陈鸿森 "中央"研究院历史语言研究所

马宗琏为清代《诗经》学名家马瑞辰之父、姚鼐之甥,所著《春秋左传补注》三卷,与顾炎武、惠栋两家《左传补注》并称,刘文淇祖孙著《春秋左氏传旧注疏证》颇参用其说。乾隆中,汉学蔚兴,桐城诸家多崇尚宋学,于汉学考据抨击不遗余力;马宗... 详细信息

马宗琏为清代《诗经》学名家马瑞辰之父、姚鼐之甥,所著《春秋左传补注》三卷,与顾炎武、惠栋两家《左传补注》并称,刘文淇祖孙著《春秋左氏传旧注疏证》颇参用其说。乾隆中,汉学蔚兴,桐城诸家多崇尚宋学,于汉学考据抨击不遗余力;马宗琏父子生长于桐城,独精研汉学,可谓卓尔特立之士。方今治《诗经》学者,莫不知有马瑞辰其人;马宗琏虽《清史列传》卷六十九、《清史稿》卷四八二、《桐城耆旧传》卷十有传,然传文简略,事迹日就湮霾。兹钩稽群籍,分就下列五事:(一)马宗琏生卒年岁、(二)马宗琏等分纂《经籍籑诂》年代考、(三)马宗琏分纂《史籍考》史实钩沉、(四)马宗琏游幕粤东之年、(五)马宗琏殿试罚科索隐。各详其事原委,以补史传之缺略,藉为论世知人之资。

关键词：马宗琏马瑞辰《经籍籑诂》《史籍考》乾嘉学术

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