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Expert consensus on the diagnosis and treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children

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World Journal of Pediatrics 2024年第9期20卷 901-914页

作者： Ying-Shuo Wang Yun-lian Zhou Guan-Nan Bai Shu-Xian li Dan Xu li-Na chen Xing chen Xiao-Yan Dong Hong-min Fu Zhou Fu chuang-li Hao Jian-Guo Hong En-Mei liu Han-min liu Xiao-Xia Lu Zheng-Xiu Luo Lan-fang Tang Man Tian Yong Yin Xiao-Bo Zhang Jian-Hua Zhang Hai-lin Zhang De-Yu Zhao Shun-Ying Zhao Guo-Hong Zhu Ying-Xue Zou Quan Lu Yuan-Yuan Zhang Zhi-min chen Department of Pulmonology Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China Department of Child Health Care Children’s HospitalZhejiang University School of MedicineNational Clinical Research Center for Child HealthHangzhou 310052China Department of Pediatric Pulmonology and Immunology West China Second University HospitalSichuan UniversityChengdu 610041China Department of Pediatrics Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250021China Department of Pulmonology Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200062China Department of Pulmonary and Critical Care Medicine Kunming Children’s HospitalKunming 650034China Department of Respiratory Medicine Children’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Pulmonology Children’s Hospital of Soochow UniversitySuzhou 215003China Department of Pediatrics Shanghai General Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghai 200080China Department of Respiratory Medicine Wuhan Children’s HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430015China Department of Respiratory Medicine Children’s Hospital of Nanjing Medical UniversityNanjing 210008China Department of Respiratory Medicine Shanghai Children’s Medical CenterShanghai Jiao Tong University School of MedicineShanghai 200127China Department of Respiratory Medicine Children’s Hospital of Fudan UniversityShanghai 201102China Department of Pediatric Pulmonology Xinhua HospitalShanghai Jiaotong University School of MedicineShanghai 201102China Department of Pediatric Respiratory Medicine The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhou 325027China National Clinical research center for Respiratory Diseases Beijing Children’s HospitalCapital Medical UniversityBeijing 100045China Departmen

Background Mycoplasma pneumoniae(***)is a significant contributor to community-acquired pneumonia among *** 1968,when a strain of *** resistant to macrolide antibiotics was initially reported in Japan,macrolide-resistant ***(MRMP)has been documented in many countries worldwide,with varying incidence *** infections lead to a poor response to macrolide antibiotics,frequently resulting in prolonged fever,extended antibiotic treatment,increased hospitalization,intensive care unit admissions,and a significantly higher proportion of patients receiving glucocorticoids or second-line *** 2000,the global incidence of MRMP has gradually increased,especially in East Asia,which has posed a serious challenge to the treatment of *** infections in children and attracted widespread attention from ***,there is still no global consensus on the diagnosis and treatment of MRMP in *** We organized 29 Chinese experts majoring in pediatric pulmonology and epidemiology to write the world’s first consensus on the diagnosis and treatment of pediatric MRMP pneumonia,based on evidence *** evidence searches and reviews were conducted using electronic databases,including PubMed,Embase,Web of Science,CNKI,Medline,and the Cochrane *** used variations in terms for“macrolide-resistant”,“Mycoplasma pneumoniae”,“MP”,“***”,“pneumonia”,“MRMP”,“lower respiratory tract infection”,“Mycoplasma pneumoniae infection”,“children”,and“pediatric”.Results Epidemiology,pathogenesis,clinical manifestations,early identification,laboratory examination,principles of antibiotic use,application of glucocorticoids and intravenous immunoglobulin,and precautions for bronchoscopy are *** and rapid identification of gene mutations associated with MRMP is now available by polymerase chain reaction and fluorescent probe techniques in respiratory *** the resistance rate to mac

关键词： Child Macrolide-resistant Mycoplasma pneumoniae Recommendation Diagnosis Treatment

The Impact of Tohoku-Oki Earthquake on “CMONOC” Stations

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The Impact of Tohoku-Oki Earthquake on “CMONOC” Stations

Simulation Analysis for the Influences of Vehicle Maneuvers to the Attitude Estimations of gnss/INS Navigation Systems

第三届中国卫星导航学术年会

作者： chen kejie,fang rongxin,li min,shi chuang gnss research center,wuhan university,wuhan,4.0079,china

In order to analyze the impact of the Mw 9.0 Tohoku-Oki earthquake occurring in 11th,March,2011 upon basic stations of "Crustal Movement Observation Network of china",the paper selects 6-day long pre-seismic GPS observation data and 3-day long post-seismic GPS data,processing them by using PANDAsoftware’s Precise Point Positioning module,thus pre-seismic and post-seismic combined coordinate solutions of the stations are obtained,and co-seismic displacement caused by the earthquake is analyzed.

关键词： Tohoku-Oki earthquake CMONOC Precise Point Positioning Co-seismic displacement

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Simulation Analysis for the Influences of Vehicle Maneuvers ...

gnss不同区域站网分布对极移精度的影响分析

第三届中国卫星导航学术年会

作者： You li, Qijin chen, Xiaoji Niu, chuang shi gnss research center, wuhan university, wuhan, china, 4.0079

gnss/INS integrated navigation systems can be used as a positioning and orientation system （POS） to provide high precision attitude and position in Mobile Mapping Systems （MMS）,. The attitude （roll, pitch, and yaw） errors will diverge with time when the vehicle is moving with low dynamics （e.g. no changes of attitude and acceleration）, which makes the attitude estimation weakly observable. This is one dominant error source in the POS applications. It can be mitigated by making corresponding vehicle maneuvers to make the navigation states observable. In this paper, the influences of different vehicle maneuvers to the attitude estimation errors are analyzed through simulation method. Results have shown that the motion with time-varying angular rates or accelerations can enhance the yaw estimation, while uniform circular motion is not useful for yaw error estimation. The outcomes of this paper can provide reference to the motion design of the MMS vehicles to maintain the attitude accuracy of the POS.

关键词： gnss/INS positioning and orientation system (POS) observability analysis attitude errors vehicle maneuvering motion design

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导航定位学报 2024年第2期12卷 70-78页

作者：方欣颀范磊李宗楠施闯北京航空航天大学卫星导航与移动通信融合技术工信部重点实验室北京100191 北京航空航天大学电子信息工程学院北京100191 北京航空航天大学前沿科学技术创新研究院北京100191 国防科技大学电子科学学院长沙410073

针对利用中国区域全球卫星导航系统(gnss)站网求解极移参数存在Y分量精度显著低于X分量的问题,提出利用姿态测量几何分析方法分析gnss不同区域站网分布对极移精度的影响:利用9个不同区域站网求解极移参数探究站网区域分布的影响;并以国... 详细信息

针对利用中国区域全球卫星导航系统(gnss)站网求解极移参数存在Y分量精度显著低于X分量的问题,提出利用姿态测量几何分析方法分析gnss不同区域站网分布对极移精度的影响:利用9个不同区域站网求解极移参数探究站网区域分布的影响;并以国际地球自转服务组织(IERS)产品为基准评估精度。结果表明,当区域站网的平均子午面与0°子午面的夹角小于45°时,X分量差异的标准差通常大于Y分量;夹角大于45°时,Y分量差异标准差通常大于X分量。为最小代价地进一步提升Y分量精度,通过在中国区域站网基础上引入全球不同位置的单个测站,评估精度提升比例。结果表明,在非洲东南部和澳大利亚地区引入单个测站将Y分量均值平均减小了80%,标准差减小了50%,较全球其他地区测站的提升效果更明显;新增美洲地区测站时存在测量奇点,易造成法方程的矩阵奇异,这是由于美洲测站、国内测站地心矢量及地球自转轴共面,从而削弱了方程结构。

关键词：极移参数姿态测量几何分析全球卫星导航系统(gnss) 不同区域站网

Biomass-Derived Materials for Electrochemical Energy Storage and Conversion: Overview and Perspectives

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Energy & Environmental Materials 2019年第1期2卷 55-67页

作者： fang Yu shizhen li Wanru chen Tao Wu chuang Peng School of Resource and Environmental Sciences Shenzhen Research InstituteWuhan University299 Bayi Road430072 WuhanChina New Materials Institute The University of Nottingham Ningbo China315100 NingboChina

Electrochemical energy storage and conversion(EESC) technology is key to the sustainable development of human society. As an abundant and renewable source, biomass has recently shown widespread applications in EESC, achieving both low environmental impact and high performances. This article provides overview and perspectives on various types of biomassderived materials, their preparation, the role in EESC and the desired features, performances and limitations, and future research efforts.

关键词： biomass battery energy storage fuel cells supercapacitor

GSTAR:an innovative software platform for processing space geodetic data at the observation level

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Satellite Navigation 2023年第3期4卷 122-141页

作者： chuang shi shiwei Guo Lei Fan Shengfeng Gu Xinqi fang linghao Zhou Tao Zhang Zhen li min li Wenwen li cheng Wang Yidong Lou Key Laboratory of Navigation and Communication Fusion Technology Ministry of Industry and Information Technology37 Xueyuan RoadBeijing 100191China School of Electronic and Information Engineering Beihang University37 Xueyuan RoadBeijing 100191China research Institute for Frontier Science Beihang University37 Xueyuan RoadBeijing 100191China gnss research center Wuhan University129 Luoyu RoadWuhan 430079China

To meet the demands for the data combination with multiple space geodetic techniques at the observation level,we developed a new software platform with high extensibility and computation efficiency,named space Geodetic SpatioTemporal data Analysis and research software(GSTAR).Most of the modules in the GSTAR are coded in C++with object-oriented *** layered modular theory is adopted for the design of the software,and the antenna-based data architecture is proposed for users to construct personalized geodetic application scenarios *** initial performance of the GSTAR software is evaluated by processing the Global Navigation Satellite System(gnss)data collected from 315 globally distributed stations over two and a half *** accuracy of gnss-based geodetic products is evaluated by comparing them with those released by International gnss Service(IGS)Analysis centers(AC).Taking the products released by European Space Agency(ESA)as reference,the Three-Dimension(3D)Root-Mean-Squares(RMS)of the orbit differences are 2.7/6.7/3.3/7.7/21.0 cm and the STandard Deviations(STD)of the clock differences are 19/48/16/32/25 ps for Global Positioning System(GPS),GLObal NAvigation Satellite System(GLONASS),Galileo navigation satellite system(Galileo),BeiDou Navigation Satellite System(BDS),Medium Earth Orbit(MEO),and BDS Inclined Geo-Synchronous Orbit(IGSO)satellites,*** mean values of the X and Y components of the polar coordinate and the Length of Day(LOD)with respect to the International Earth Rotation and Reference Systems Service(IERS)14 C04 products are-17.6 microarc-second(μas),9.2μas,and 14.0μs/*** to the IGS daily solution,the RMSs of the site position differences in the north/east/up direction are 1.6/1.5/3.9,3.8/2.4/7.6,2.5/2.4/7.9 and 2.7/2.3/7.4 mm for GPS-only,GLONASS-only,Galileo-only,and BDS-only solution,*** RMSs of the differences of the tropospheric Zenith Path Delay(ZPD),the north gradients,and the east gradien

关键词： GSTAR gnss BDS LEO Precise orbit determination Precise clock estimation Earth rotation parameter Tropospheric zenith path delay Geocenter motion Rapid data processing

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4种不同品种玫瑰精油的检测及成分分析

中国调味品 2024年第8期49卷 149-154页

作者：陶永霞安比芳陈创业乔桂芳冯作山新疆农业大学食品科学与药学学院乌鲁木齐830052

试验以大马士革玫瑰、紫枝玫瑰、丰花玫瑰、苦水玫瑰为研究对象,利用水蒸气蒸馏法从4种玫瑰中提取精油,采用气相色谱-质谱法(GC-MS)对不同品种玫瑰精油挥发性物质进行定性定量分析,并通过主成分分析(PCA)和聚类分析(CA)对玫瑰精油进行... 详细信息

试验以大马士革玫瑰、紫枝玫瑰、丰花玫瑰、苦水玫瑰为研究对象,利用水蒸气蒸馏法从4种玫瑰中提取精油,采用气相色谱-质谱法(GC-MS)对不同品种玫瑰精油挥发性物质进行定性定量分析,并通过主成分分析(PCA)和聚类分析(CA)对玫瑰精油进行判定、区分和聚集。结果表明,GC-MS检测得到玫瑰精油含有65种挥发性物质,对其进行主成分分析,可以简化为3个主成分,前两个主成分的累计方差贡献率为81.952%,可反映玫瑰的大部分信息,通过主成分分析将4种玫瑰精油分为两大类:大马士革玫瑰精油和紫枝玫瑰精油为一类,丰花玫瑰精油和苦水玫瑰精油为一类。不同玫瑰品种挥发性物质组成多样,该研究以期为今后的精油提取和分析提供一定的理论基础。

关键词： 4种玫瑰精油水蒸气蒸馏法气相色谱-质谱法(GC-MS) 主成分分析(PCA) 聚类分析(CA)

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On single particle breakage behavior of crushable weathered sands

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Journal of Mountain Science 2022年第12期19卷 3627-3644页

作者： YU fang-wei ZHAO chuang liU Wei-chen Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610299China center for Excellence in Tibetan Plateau Earth Sciences Chinese Academy of SciencesBeijing 100101China university of Chinese Academy of Sciences Beijing 100049China china-Pakistan Joint research centeron Earth Sciences Islamabad 45320Pakistan Department of Civil Engineering The University of TokyoTokyo 113-8656Japan Department of Civil Engineering Zhejiang UniversityHangzhou 310058China

This paper presents an experimental study on single particle breakage behavior of crushable weathered sands by a number of single particle uniaxial compression tests to comprehensively investigate the characteristics of single particle breakage,the probability of survival of single particle,and the effects of particle size and weathering on single particle *** behavior of single particle under uniaxial compression falls into the mixed five phases:damage by chipping,elastic deformation,fragmentation by partial fracture,breakage by splitting,and the residuals,demonstrating the complexity and variability of the tensile strengths of single *** behavior of single particle breakage was quantified herein by the initial fracture and failure strengths of single *** probability of survival decreased as the characteristic stresses *** increase in the particle size or weathering number of single particle resulted in a reduction in the probability of survival of single *** a given probability of survival,the difference in the initial fracture characteristic stress and failure characteristic stress decreased with increasing particle size but showed a complex change with increasing weathering *** probability of survival showed greater variability for the normalized initial fracture characteristic stress than for the normalized failure characteristic stress,implying that the initial fracture stresses of single particles diverged more than the failure stresses of the *** average initial fracture and failure characteristic stresses,and the initial fracture and failure characteristic stresses corresponding to 1/e(37%)survival of single particles decreased while increasing particle size or weathering number,but the decrease showed a sharper rate for smaller single particles with a lower weathering *** ln-ln coordinates showed a linear representation of the failure characteristic stress and particle size,verifying th

关键词： Breakage Compression Particle size Probability of survival Sands Weathering

Galileo高精度定位服务的空间信号误差及精密单点定位评估

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全球定位系统 2024年第3期49卷 1-9页

作者：丁尧方荣新陈国胡冰燕程毅凡武汉大学测绘学院武汉430079 武汉大学卫星导航定位技术研究中心武汉430079

Galileo高精度定位服务(high accuracy service,HAS)利用E6B信号向全球用户播发免费精密卫星轨道、钟差和码偏差改正信息,在卫星高精度实时应用领域有重要意义.评估其空间信号误差及精密单点定位(precise point positioning,PPP)性能是... 详细信息

Galileo高精度定位服务(high accuracy service,HAS)利用E6B信号向全球用户播发免费精密卫星轨道、钟差和码偏差改正信息,在卫星高精度实时应用领域有重要意义.评估其空间信号误差及精密单点定位(precise point positioning,PPP)性能是用好HAS的重要前提.基于2023年12月1日至31日的HAS轨道钟差产品进行评估测试,Galileo卫星轨道产品在径向(R)、切向(A)和法向(C)的均方根误差(root mean square error,RMSE)分别为3.24 cm、7.40 cm和6.85 cm,GPS分别为4.52 cm、8.19 cm和6.71 cm;Galileo钟差产品的标准差(standard deviation,STD)为0.16 ns,GPS为0.26 ns.基于欧洲10个测站PPP的实验结果表明:Galileo在E、N、U方向的定位精度分别为6.44 cm、4.65 cm和11.36 cm,GPS分别为7.42 cm、5.78 cm和12.04 cm,联合定位分别为4.11 cm、3.10 cm和7.56 cm,HAS可以满足高精度定位需求.

关键词： Galileo高精度定位服务(HAS) 可用性分析空间信号误差精密单点定位(PPP)

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