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Experimental research and numerical simulation of RC beams strengthened with bonded steel plates

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Science China(Technological Sciences) 2012年第12期55卷 3270-3277页

作者： LEI Dong chen guangyuan chen YuQuan REN QingWen State Key Laboratory of Hydrology-Water Rexources and Hydraulic Engineering Hohai UniversityNanjing 210098China College of Mechanics and Materials Hohai UniversityNanjing 210098China

It is a common method to strengthen the damaged RC structures with bonded steel plates. At present the ultimate bearing ca- pacity of RC structures strengthened with bonded steel plates is calculated mostly using the theory based on the test. Four beams, including one reference beam, two strengthened concrete beams in primary force and secondary force respectively, and one strengthened concrete beam which was not anchored enough, were tested under four-point bending (4PB) in order to get the data of strain of longitudinal bars, bonded bottom steel plate in tension and deflection of beams in the middle span. The experimental program was supported by a three-dimensioned finite analysis using ABAQUS. At the end of experiments and finite analysis, it is concluded that the investing strengthening technique can significantly improve the load-carrying capacity and the phenomenon of stress concentration at the end of interface, as well as the damage at interface, can be well simulated with cohesive element provided by ABAQUS.

关键词： RC beams, strengthened with bonded steel plates secondary force, finite element analysis, damage of interface

lncRNA NEAT1调节miR-424-5p/ELK4轴对ox-LDL诱导的血管内皮细胞损伤、Lp-PLA2和CRP水平的影响

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中西医结合心脑血管病杂志 2024年第4期22卷 653-659页

作者：陈光远边毓尧王秀艳内蒙古自治区人民医院呼和浩特010017 河北中石油中心医院河北廊坊065000

目的:探讨长链非编码RNA核旁斑组装转录本1(lncRNA NEAT1)在氧化型低密度脂蛋白(ox-LDL)诱导的血管内皮细胞损伤中的分子机制和功能。方法:收集健康人和动脉粥样硬化(AS)病人血液标本并通过实时荧光定量逆转录聚合酶链式反应(qRT-PCR)... 详细信息

目的:探讨长链非编码RNA核旁斑组装转录本1(lncRNA NEAT1)在氧化型低密度脂蛋白(ox-LDL)诱导的血管内皮细胞损伤中的分子机制和功能。方法:收集健康人和动脉粥样硬化(AS)病人血液标本并通过实时荧光定量逆转录聚合酶链式反应(qRT-PCR)检测血清中lncRNA NEAT1、微小RNA-424-5p(miR-424-5p)和ETS域蛋白4(ELK4)mRNA表达水平。体外培养人脐静脉内皮细胞(HUVEC),qRT-PCR和蛋白免疫印迹法(Western Blot)检测细胞中lncRNA NEAT1、miR-424-5p和ELK4表达情况;细胞计数试剂盒(CCK-8)法和膜联蛋白V-异硫氰酸荧光素/碘化丙啶(Annexin V-FITC/PI)法检测HUVEC细胞增殖活力和凋亡情况;酶联免疫吸附法(ELISA)测定HUVEC中乳酸脱氢酶(LDH)释放量、肿瘤坏死因子-α(TNF-α)和白细胞介素(IL)-1β含量、脂蛋白磷脂酶A2(Lp-PLA2)和C反应蛋白(CRP)水平;采用双荧光素酶报告基因测定lncRNA NEAT1、miR-424-5p和ELK4之间的靶向相互作用。进行动物实验以评估lncRNA NEAT1在体内AS进展中的作用。结果:lncRNA NEAT1在AS病人血清和ox-LDL诱导的HUVEC中显著上调(P<0.05)。lncRNA NEAT1的沉默可削弱ox-LDL引发的细胞毒性,降低Lp-PLA2和CRP水平,并减少ApoE^(-/-)小鼠的脂质异常分泌(P<0.05)。miR-424-5p是lncRNA NEAT1在调节ox-LDL诱导的HUVEC损伤中的功能介质,ELK4是miR-424-5p的直接靶标(P<0.05)。miR-424-5p的抑制或ELK4的过表达逆转了lncRNA NEAT1沉默对ox-LDL诱导的HUVEC细胞损伤的影响(P<0.05)。结论:沉默lncRNA NEAT1可通过调控miR-424-5p/ELK4轴保护HUVEC免受ox-LDL触发的细胞毒性,降低Lp-PLA2和CRP水平。

关键词：动脉粥样硬化长链非编码RNA核旁斑组装转录本1,lncRNA NEAT1 氧化型低密度脂蛋白微小RNA-424-5p ETS域蛋白4 实验研究

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心脏除颤仪自动体外除颤和起搏功能质控检测实践方法探讨

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中国医疗设备 2024年第1期39卷 50-55,60页

作者：麦达成肖翔陈远鹏胡智勇陈广源广州市番禺区中心医院设备科广东广州511400 广州市番禺区中心医院行政办公室广东广州511400 广州市番禺质量技术监督检测所电学室广东广州511400

目的研究心脏除颤仪自动体外除颤和起搏功能的质量控制检测方法,完善心脏除颤仪日常运维管理,保障临床急救能力。方法根据心脏除颤仪自动体外除颤和起搏的原理,结合各模拟器、质控检测工具的功能情况,研定从自动体外除颤功能的“电击... 详细信息

目的研究心脏除颤仪自动体外除颤和起搏功能的质量控制检测方法,完善心脏除颤仪日常运维管理,保障临床急救能力。方法根据心脏除颤仪自动体外除颤和起搏的原理,结合各模拟器、质控检测工具的功能情况,研定从自动体外除颤功能的“电击心律识别、自动体外放电时间、释放能量”和起搏功能的“起搏脉冲电流、起搏脉冲宽度、起搏脉率”6个维度进行质控检测。结果制定自动体外除颤和起搏功能质控表格,研究明确一次性电极片的替代办法,同时通过实测番禺区23台心脏除颤仪,得到电击心律识别检测的合格率为100%,自动体外除颤放电时间、自动除颤释放能量(最大偏差)、起搏脉冲电流(最大偏差)、起搏脉冲宽度(最大偏差)内容均符合规程要求(P<0.05)的质控检测结果。结论本院制定的心脏除颤仪自动体外除颤和起搏功能质控检测方法能切实检测自动体外除颤和起搏功能的精准性,确保心脏除颤仪功能正常,保障医疗安全。

关键词：心脏除颤仪自动体外除颤起搏质控检测

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跨运营铁路线盖梁施工技术及应用

江西建材 2024年第2期 268-271页

作者：辛永杨海波陈光远山东高速路桥国际工程有限公司山东济南250014

为解决桥梁施工中跨运营铁路线等复杂环境施工困难等技术问题,文中以孟加拉达卡机场高架快速路建设项目为例,针对需骑行现有运营铁路线较长的问题,研发了新型可移动式门架辅助支撑系统,解决了跨运营铁路线桥梁施工空间狭小、施工时间紧... 详细信息

为解决桥梁施工中跨运营铁路线等复杂环境施工困难等技术问题,文中以孟加拉达卡机场高架快速路建设项目为例,针对需骑行现有运营铁路线较长的问题,研发了新型可移动式门架辅助支撑系统,解决了跨运营铁路线桥梁施工空间狭小、施工时间紧张等问题。

关键词：盖梁施工可移动式门架系统骑行运营铁路线

Effects of heavy metal ions Cu^(2+)/Pb^(2+)/Zn^(2+)on kinetic rate constants of struvite crystallization

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Chinese Journal of Chemical Engineering 2023年第5期57卷 10-16页

作者： guangyuan chen Tong Zhou Meng Zhang Zhongxiang Ding Zhikun Zhou Yuanhui Ji Haiying Tang Changsong Wang State Key Laboratory of Materials-Oriented Chemical Engineering Nanjing Tech UniversityNanjing 211816China Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research School of Chemistry and Chemical EngineeringSoutheast UniversityNanjing 211189China Qinghai Salt Lake Yuantong Potash Fertilizer Co. Ltd.Golmud 816000China

Struvite(MAP)crystallization technology is widely used to treat ammonia nitrogen in waste effluents of its simple operation and good removal ***,the presence of heavy metal ions in the waste effluents causes problems such as slow crystallization rate and small crystal size,limiting the recovery rate and economic value of the *** present study was conducted to investigate the effects of concentrations of three heavy metal ions(Cu^(2+),Zn^(2+),and Pb^(2+))on the crystal morphology,crystal size,average growth rate,and crystallization kinetics of MAP.A relationship was established between the kinetic rate constant Ktcalculated by the chemical gradient model and the concentrations of heavy metal *** results showed that low concentrations of heavy metal ions in the solution created pits on the MAP surface,and high level of heavy metal ions generated flocs on the MAP surface,which were composed of metal hydroxides,thus inhibiting crystal *** crystal size,average growth rate,MAP crystallization rate,and kinetic rate constant Ktdecreased with the increase in heavy metal ion ***,the Ktdemonstrated a linear relationship with the heavy metal concentration ln(C/C~*),which provided a reference for the optimization of the MAP crystallization process in the presence of heavy metal ions.

关键词： Struvite Crystallization Heavy metal ions Kinetics Kinetic modeling Kinetic rate constant

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城市综合管理视角下的城市更新着力点研究

城市管理与科技 2024年第1期25卷 16-19页

作者：秦常清张鹏丁杰田靖源陈光远重庆市停车管理事务中心重庆市城市综合管理工作领导小组办公室重庆市环境卫生事务中心重庆市城市供节水事务中心

党的二十大报告提出,实施城市更新行动,打造宜居、韧性、智慧城市。重庆作为超大山水城市,全市正在努力建设现代化新重庆,城市管理部门正在谋划思考如何把城市综合管理工作积极融入到现代化新重庆建设宏大场景中。为了找准在城市更新国... 详细信息

党的二十大报告提出,实施城市更新行动,打造宜居、韧性、智慧城市。重庆作为超大山水城市,全市正在努力建设现代化新重庆,城市管理部门正在谋划思考如何把城市综合管理工作积极融入到现代化新重庆建设宏大场景中。为了找准在城市更新国家战略中的切入点和着力点,本文从城市更新面临的三个“更加注重”新趋势,梳理了重庆市城市更新现状及问题,结合典型山地城市特色,提出了针对性对策建议。

关键词：城市更新城市综合管理山水城市针对性对策智慧城市城市管理部门宜居着力点

Nitrogen-rich carbon nitrogen polymers for enhancing the sorption of uranyl

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Chinese Chemical Letters 2022年第7期33卷 3468-3473页

作者： Zeru Wang Wenhao Li Linzhen Wu Zhuang Wang Yalan Cao Jingkai cheng guangyuan chen Qian Zhao Mei Jiang Zhengguo chen Lin Zhu Tao Duan National Co-Innovation Center for Nuclear Waste Disposal and Environmental Safety Southwest University of Science and TechnologyMianyang 621010China State Key Laboratory of Environment-friendly Energy Materials School of National Defence Science and TechnologySouthwest University of Science and TechnologyMianyang 621010China College of Chemistry Sichuan UniversityChengdu 610064China School of Physics and Astronomy China West Normal UniversityNanchong 637002China NHC Key Laboratory of Nuclear Technology Medical Transformation Mianyang Central HospitalMianyang 621010China

Nitrogen enrichment and increased nitrogen content is an effective strategy for enhancing adsorption of uranium by carbon nitride ***,we reported the uranium absorption by using a structurally well-defined and nitrogen-rich carbon nitride polymer with C_(3)N_(5) stoichiometry for the first *** comparison with the adsorption performance of g-C_(3)N_(4) for U(Ⅵ),the conjugation system of the material was increased by connecting the heptazine unit through the azo bridge in the structure of C_(3)N_(5),so that C_(3)N_(5) exhibited several times higher adsorption performance than that of g-C_(3)N_(4).The C_(3)N_(5) has high kinetics for uranyl ions,which can adsorb100 mg/g U(Ⅵ)in only 10 min and reach complete adsorption equilibrium in 60 min;the theoretical maximum adsorption capacity is 207 mg/g,meanwhile,the material exhibits high *** results of spectral analysis and theoretical calculations indicate that the process of uranyl ion capture by C3N5is a combination of physical and chemical adsorption,and its higher density of electronic states makes the electrostatic binding ability enhanced,which is favorable to the adsorption of uranyl ions by C_(3)N_(5).This work indicates that C_(3)N_(5) has great promise and application in the separation and enrichment of uranyl ions,and also provides a reference for the systematic investigation of the adsorption ability of nitrogenrich carbon nitrogen polymers on uranyl ions.

关键词： Uranium Nitrogen enrichment Carbon nitride C_(3)N_(5) Adsorption

Flexible,high-density,laminated ECoG electrode array for high spatiotemporal resolution foci diagnostic localization of refractory epilepsy

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Bio-Design and Manufacturing 2024年第4期7卷 388-398页

作者： Yafeng Liu Zhouheng Wang Yang Jiao Ying chen guangyuan Xu Yinji Ma Xue Feng Applied Mechanics Laboratory Department of Engineering MechanicsTsinghua UniversityBeijing 100084China Laboratory of Flexible Electronics Technology Tsinghua UniversityBeijing 100084China College of Artificial Intelligence Southwest UniversityChongqing 400715China Institute of Flexible Electronics Technology of THU Jiaxing 314000China Qiantang Science and Technology Innovation Center Hangzhou 310016China School of Artificial Intelligence Beijing University of Posts and TelecommunicationsBeijing 100876China

High spatiotemporal resolution brain electrical signals are critical for basic neuroscience research and high-precision focus diagnostic localization,as the spatial scale of some pathologic signals is at the submillimeter or micrometer *** entails connecting hundreds or thousands of electrode wires on a limited *** study reported a class of flexible,ultrathin,highdensity electrocorticogram(ECoG)electrode *** challenge of a large number of wiring arrangements was overcome by a laminated structure design and processing technology *** flexible,ultrathin,high-density ECoG electrode array was conformably attached to the cortex for reliable,high spatial resolution electrophysiologic *** minimum spacing between electrodes was 15μm,comparable to the diameter of a single *** hundred electrodes were prepared with an electrode density of 4444 mm^(-2).In focal epilepsy surgery,the flexible,high-density,laminated ECoG electrode array with 36 electrodes was applied to collect epileptic spike waves inrabbits,improving the positioning accuracy of epilepsy lesions from the centimeter to the submillimeter *** flexible,high-density,laminated ECoG electrode array has potential clinical applications in intractable epilepsy and other neurologic diseases requiring high-precision electroencephalogram acquisition.

关键词： Electrocorticogram(ECoG)electrode Epilepsy High density High resolution Laminated structure

A tactile and airflow motion sensor based on flexible double-layer magnetic cilia

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Microsystems & Nanoengineering 2023年第1期9卷 127-135页

作者： Jiandong Man Junjie Zhang guangyuan chen Ning Xue Jiamin chen State Key Laboratory of Transducer Technology Aerospace Information Research InstituteChinese Academy of Sciences100190BeijingPeople’s Republic of China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of Sciences100049BeijingPeople’s Republic of China

Inspired by the concept of bionics,a tactile and airflow motion sensor based on flexible double-layer magnetic cilia is developed,showing extremely high sensitivity in both force and airflow *** upper layer of the magnetic cilia is a flexible material mixed with magnetic particles,while the lower layer is a pure flexible *** double-layer structure significantly improves magnetism while maintaining cilia *** addition,a metal tube pressing(MTP)method is proposed to overcome the difficulties in preparing large aspect ratio(over 30:1)cilia,offering simplicity and avoiding the use of large-scale MEMS *** developed sensor has a detection range between 0 and 60µN with a resolution of 2.1µN for micro *** also shows great detection ability for airflow velocity with a sensitivity of 1.43µT/(m/s).Experiments show that the sensor could be applied in surface roughness characterization and sleep apnea monitoring.

关键词： layer double motion