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Laparoscopic, Endoscopic and Robotic Surgery 2021年第4期4卷 121-124页

作者： James Wei Tatt Toh Henry Wang Geoffrey Collins chelsea Beinke Elissa Zhang Alistair Escott Toufic El-Khoury Nimalan Pathma-Nathan Discipline of Surgery Sydney Medical SchoolThe University of SydneySydneyAustralia Colorectal Department Westmead HospitalSydneyAustralia The University of Notre Dame SydneyAustralia

Restorative low anterior resection(LAR)for rectal cancer carries a significant risk of anastomotic leak:One of the most feared complications in colorectal *** management may include takedown of the anastomosis and end colostomy which,in some cases,is *** contemporary operative measures include over the scope clips and ***,there have been case reports and a Society of American Endoscopic and Gastrointestinal Surgeons video on the novel use of transanal minimally invasive surgery(TAMIS)in the management of anastomotic *** present a 59-year-old female who underwent LAR after declining radiotherapy for a bulky 9 cm rectal tumour 9-10 cm from the anal *** clinical deterioration,computed tomography demonstrated an anastomotic leak communicating with a 5-cm pelvic collection containing *** laparoscopy,pus and faeculent material were washed from the pelvic cavity and drains were ***-operative endoscopy demonstrated a 7-8 mm dehiscence at the *** defect(approximately 7 cm from the anal verge)was successfully closed using TAMIS and a running V-lock *** patient recovered well and was discharged home on post-operative day *** this case,a low colorectal anastomotic leak was successfully rescued with *** novel technique may be useful in the armamentarium of colorectal surgeons experienced in TAMIS.

关键词： Transanal minimally invasive surgery Anastomotic leak Low anterior resection Colorectal cancer

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海滩上的风向标聚焦ABMB

今日财富 2016年第Z1期 61-67,60页

作者： chelsea

一年一度的迈阿密海滩巴塞尔艺博会又如期而至,这个北美最大的艺术交易盛会聚集了全世界有钱有闲并热爱艺术的人们。伴着阳光明媚的沙滩,温热的海水,各国巨富、名流们带着万干身家如潮水般涌来,过足了购物的瘾,也指明了下一年美洲艺术... 详细信息

一年一度的迈阿密海滩巴塞尔艺博会又如期而至,这个北美最大的艺术交易盛会聚集了全世界有钱有闲并热爱艺术的人们。伴着阳光明媚的沙滩,温热的海水,各国巨富、名流们带着万干身家如潮水般涌来,过足了购物的瘾,也指明了下一年美洲艺术市场的新趋势。

关键词：巴塞尔 ABMB 艺博会策展人参展艺术家尼亚主场馆创办人拉丁美洲地区比亚

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XHTML教程

2001年

作者：（美）chelsea Valentine （美）Chris Minnick 贺军傅蓉译

本书主要内容包括XHTML的历史、置标语言、有关XHTML元素的全部语法及语义，从HTML到XHTML的转换，使用XHTML创建传送Web内容的大量示例及讨论等。

ISBN: (纸本)7115093024

本书主要内容包括XHTML的历史、置标语言、有关XHTML元素的全部语法及语义，从HTML到XHTML的转换，使用XHTML创建传送Web内容的大量示例及讨论等。

关键词：制作网页软件工具

来源：畅想之星图书光盘版（南... 评论

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理想国

今日财富 2016年第Z1期 68-75页

作者： chelsea

王国锋作为目前唯一一位获得朝鲜官方认可并前往拍摄的艺术家,他的摄影作品中最著名的应该就是被称作"社会主义系列"的作品。在朝鲜政府的接待下和协助下,他的系列有关于朝鲜的作品看起来与游客和媒体所拍摄的视角有所不同。从"理想"到... 详细信息

王国锋作为目前唯一一位获得朝鲜官方认可并前往拍摄的艺术家,他的摄影作品中最著名的应该就是被称作"社会主义系列"的作品。在朝鲜政府的接待下和协助下,他的系列有关于朝鲜的作品看起来与游客和媒体所拍摄的视角有所不同。从"理想"到"新闻系列",王国锋的作品无一不具有深刻的艺术观念性和社会性特征,通过建筑浓缩和体现人类政治社会中模式化的社会制度和高度集权统治下的"集体无意识"。

关键词：摄影作品社会性特征集权统治人类政治观念性集体无意识新闻图片上图新闻系视觉化

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红色新年

今日财富 2016年第Z1期 108-113页

作者： chelsea

红,象征热情、喜兴、高贵、吉祥,在中国传统文化里,红,又代表着正直、好运与神圣。在珠宝里,红色的珠宝也很多,她们有着各自的特点与魅力,代表着不同的意义与内涵。在中国人的视角中,节庆与红色始终脱不了干系,遇到新年春节,就更加愿意... 详细信息

红,象征热情、喜兴、高贵、吉祥,在中国传统文化里,红,又代表着正直、好运与神圣。在珠宝里,红色的珠宝也很多,她们有着各自的特点与魅力,代表着不同的意义与内涵。在中国人的视角中,节庆与红色始终脱不了干系,遇到新年春节,就更加愿意用红色铺满四周。时光流转,嵌有红色宝石或水晶的珠宝永不退烧,始终是中国年的必备利器。红色代表喜气,红色也代表温暖,让红色的珠宝为新年带来新的喜庆气息,"红"运当头。

关键词：中国传统文化 Cartier 卡地亚时光流转欧泊胸针雅宝

DNA/RNA Degradation Rate in Long Term Fixed Museum Specimens

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Forensic Medicine and Anatomy Research 2015年第1期3卷 1-6页

作者： Shannon Cook chelsea Dodge Randy Morgan George E. Sandusky Pathology Department Indiana University School of Medicine Indianapolis USA

In today’s research driven society, it has become commonplace for institutions to rely upon DNA and RNA extraction techniques to help obtain genomic data from old specimens. Generally, specimens are preserved for future gross examination and/or teaching. Using histological examination of specimens from museum jars from the Pathology Department at the Indiana University School of Medicine, the sequential and chronological degradation of DNA and RNA has been studied. We examined gross specimens from 1920 to 2000. We evaluated histologic preservation of kidney, liver, heart, lung, spleen, uterus and brain for nuclear structure in these samples. Nuclear preservation was based on amount of nuclei per microscopic field and the crispness of the nuclear membrane and internal features. The nuclei in high lipid tissues such as the brain were found to degrade at a quicker rate than dense tissues such as the heart and uterus. Our study has shown that specimens preserved beyond fifty years were likely to have little to no nuclei left, thus indicating that there was little to no DNA and RNA remaining. This technique of histologic evaluation is an important finding and a general guideline which may save research institutions from the expensive process of DNA and RNA extraction.

关键词： DNA RNA Nuclear Degradation Microscopy

Evaluating Vancomycin Clinical Outcomes Using Area under the Curve versus Trough Based Dosing Strategies

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Advances in Infectious Diseases 2023年第3期13卷 442-451页

作者： chelsea A. Schneider William Rodriguez Jenny Martinez William R. Wolowich Department of Pharmacy Mount Sinai Medical Center Miami Beach Florida USA Department of Pharmacy Practice Nova Southeastern University Fort Lauderdale Florida USA

Background: The 2020 consensus guidelines recommend AUC guided dosing as the preferred monitoring method for vancomycin. AUC based dosing has shown to reduce incidence of acute kidney injury (AKI), utilize lower daily doses in obese patients, and maintain efficacy. Several institutions have adjusted their protocols to utilize AUC guided dosing. However, there are limited studies comparing the clinical outcomes of AUC versus trough monitoring. Methods: This was a retrospective, observational, single centered study. The primary outcome was to evaluate the clinical success of AUC dosing versus trough based dosing of vancomycin for MRSA infections using a composite outcome of afebrile post treatment ( Results: Forty-seven patients were included in this study, 17 in the AUC group and 30 in the trough group. The primary composite outcome showed a significant benefit of AUC dosing (p = 0.04). The composite component culture clearance showed the largest improvement for the AUC group when compared with the trough group (p = 0.03). More patients achieved therapeutic target attainment and reached the target sooner (3 days versus 4 days, p = 0.2) in the AUC group. Over the study course, 94.1% of patients in the AUC group were considered therapeutic compared to 63.8% in the trough group (p = 0.03). Vancomycin levels were collected less frequently in the AUC group (3 versus 4, p = 0.2). Conclusion: The outcomes of this study may suggest AUC guided dosing as a beneficial alternative to trough based dosing. AUC based dosing may improve clinical success which can be further explored in larger prospective clinical trials.

关键词： AUC MRSA Pharmacokinetics Trough Based Dosing Vancomycin

“尚绿之境:探索祖母绿世界”展览开幕——共庆“中法文化之春”

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中国宝石 2024年第4期 144-149页

作者： chelsea 无不详 LECOLE珠宝艺术中心

2024年5月25日至10月7日,L'ECOLE珠宝艺术中心在上海举办“尚绿之境:探索祖母绿世界(Garden of Emeralds,Discover the Gemstones)展览”,这既是该展览自去年9月在迪拜开幕以来在全球范围内举办的第2场展出,亦是中法建交60周年之际举办... 详细信息

2024年5月25日至10月7日,L'ECOLE珠宝艺术中心在上海举办“尚绿之境:探索祖母绿世界(Garden of Emeralds,Discover the Gemstones)展览”,这既是该展览自去年9月在迪拜开幕以来在全球范围内举办的第2场展出,亦是中法建交60周年之际举办的第18届“中法文化之春”的活动,旨在见证中法两国文化艺术互鉴,共襄珠宝与艺术的双重盛宴。

关键词：中法建交展览开幕祖母绿全球范围

PreEMPT (Preterm Infant Early Intervention for Movement and Participation Trial): The Feasibility of a Novel, Participation-Focused Early Physiotherapy Intervention Supported by Telehealth in Regional Australia—A Protocol

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Open Journal of Pediatrics 2020年第4期10卷 707-731页

作者： chelsea A. Mobbs Alicia J. Spittle Leanne M. Johnston School of Health and Rehabilitation Sciences The University of Queensland Brisbane Qld Australia Toowoomba Hospital Darling Downs Hospital and Health Service Queensland Health Qld Australia School of Physiotherapy University of Melbourne Melbourne Vic Australia

Background: Early intervention is beneficial for improving preterm infant motor and cognitive outcomes in early childhood;however, little is known about whether early intervention can influence a preterm infant’s participation. Additionally, many studies investigating the impact of early intervention for preterm infants have been conducted in large metropolitan centres, leaving preterm infants who reside in regional areas underrepresented in the literature to date. Consequentially, it is not yet known whether there are service delivery models, such as using telehealth as an adjunct to face-to-face intervention, that might cater to the needs of preterm infants residing outside metropolitan centres. PreEMPT (Preterm infant Early intervention for Movement and Participation Trial) is a novel early physiotherapy intervention that has been designed to use a participation goal-directed intervention approach via a mixture of face-to-face clinic sessions and telehealth sessions to improve the motor and participation outcomes of preterm born infants. Methods: This study aims to evaluate the feasibility of PreEMPT using an assessor-blinded, randomised controlled trial to compare PreEMPT to Usual Physiotherapy Care (UPC) for preterm infants residing in a regional Australian hospital catchment area. Twenty-six preterm infants (≤34 + 6 weeks gestational age) will be recruited prior to term corrected age from the special care nursery of a regional hospital. Following informed consent and baseline assessments, infants will be randomly allocated to receive either PreEMPT, a novel participation-focused early physiotherapy intervention delivered weekly for

关键词： Early Intervention Preterm Infants Participation Physiotherapy

生活方式干预对心血管疾病危险因素的影响——美国HELPS项目成果

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北京体育大学学报 2017年第6期40卷 48-53页

作者： Peter H.Brubaker 罗曦娟 chelsea Boltja shuchang Du Wake森林大学运动与健康科学系中山大学广东广州510275

心血管疾病(CVD)一直是全世界最主要的死因。由于CVD等慢性疾病对健康的威胁越来越大,有必要开展生活方式干预项目以控制这些疾病的危险因素。本研究的目的是评估美国的重要慢病干预项目—HELPS治疗型生活方式改变(TLC)项目对减少CVD危... 详细信息

心血管疾病(CVD)一直是全世界最主要的死因。由于CVD等慢性疾病对健康的威胁越来越大,有必要开展生活方式干预项目以控制这些疾病的危险因素。本研究的目的是评估美国的重要慢病干预项目—HELPS治疗型生活方式改变(TLC)项目对减少CVD危险因素和其他慢性疾病的有效性。方法:140位大学教职工参加为期12周的HELPS TLC项目,干预前后用配对t检验对其体重、BMI、腰围(WC)、6分钟步行距离(6MWD)、空腹血脂和血糖进行测定和比较。结果:干预后,6MWD显著增加,总胆固醇(TC)和WC显著下降。对"高危"参与者进一步分析显示:BMI(-1.5±0.5,-3.9%)、TC(-22.8±4.0,-9.0%)、LDL(-14.1±4.9,9.3%)和血糖(-6.9±2.2,-6.1%)均显著下降;男性腰围(-4.5±0.8,-10%)显著减小,女性未见显著改变(-1.5±0.5,-4.0%)。此外,体重的变化与TC(r=0.43)、LDL(r=0.35)和血糖(r=0.44)的变化均显著相关。结论:参加12周的生活方式干预项目可以使CVD危险因素减少,特别是在CVD"高危"个体中。HELPS TLC项目的远期效果还待进一步深入研究。

关键词：生活方式疾病管理运动体力活动营养危险因素心血管疾病