检索结果-南通市图书馆

Peri-operative extracorporeal membrane oxygenation in adult and pediatric living donor liver transplantation:a single-center experience

引用

Hepatobiliary Surgery and Nutrition 2023年第6期12卷 898-908,I0011页

作者： Itsuko Chih-Yi Chen Leona Bettina PDungca chee-chien yong Wei Ho Jiunn-Jye Sheu Chao-Long Chen Liver Transplantation Center Department of SurgeryKaohsiung Chang Gung Memorial HospitalKaohsiung Cardiovascular Surgery Kaohsiung Chang Gung Memorial HospitalKaohsiung

Background:Extracorporeal membrane oxygenation(ECMO)is a potential rescue therapy for patients with acute cardiopulmonary dysfunction refractory to conventional treatment.In this study,we described the clinical profiles and outcomes of adult and pediatric living donor liver transplantation(LDLT)patients who received ECMO support during the peri-operative period.Methods:From June 1994 to December 2020,eleven out of the 1,812 LDLTs performed at Kaohsiung Chang Gung Memorial Hospital required ECMO support:six for respiratory failure,three for cardiogenic shock,and two for refractory septic shock.Comparison between the survivor and non-survivor groups was made.Results:The survival rate for liver transplantation(LT)patients on ECMO support is 36.4%-40%in adults and 33.3%in pediatrics,while the survival rate per indication is as follows:acute respiratory distress syndrome(ARDS)(50%),cardiogenic shock(33.3%),and sepsis(0%).Shorter durations of LT-to-ECMO and pre-ECMO mechanical ventilation were observed in the survivor group.On the other hand,we observed persistently elevated total bilirubin levels in non-survivors,while none of the survivors had aspartate aminotransferase(AST)/alanine aminotransferase(ALT)levels>1,000 U/L.A higher proportion of non-survivors were on concurrent continuous renal replacement therapy(CRRT).Conclusions:Our experience has proven ECMO’s utility during the peri-operative period for both adult and pediatric LDLT patients,more specifically for indications other than septic shock.Further studies are needed to better understand the factors leading to poor outcomes in order to identify patients who will more likely benefit from ECMO.

关键词： Extracorporeal membrane oxygenation(ECMO) living donor liver transplantation(LDLT) respiratory failure cardiogenic shock septic shock

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proton beam therapy to bridge or downstage locally advanced hepatocellular carcinoma to living donor liver transplantation

引用

Hepatobiliary Surgery and Nutrition 2022年第1期11卷 103-111页

作者： Chao-Long Chen Aldwin D.Ong Jen-Yu Cheng chee-chien yong Chih-Che Lin Chih-Yi Chen Yu-Fan Cheng Liver Transplantation Center Department of SurgeryKaohsiung Chang Gung Memorial HospitalChang Gung University College of MedicineKaohsiungTaiwanChina Liver Transplantation Center Department of Radiation OncologyKaohsiung Chang Gung Memorial HospitalChang Gung University College of MedicineKaohsiungTaiwanChina Liver Transplantation Center Department of Diagnostic RadiologyKaohsiung Chang Gung Memorial HospitalChang Gung University College of MedicineKaohsiungTaiwanChina

Introduction Within the last decade,progress in transplant and surgical oncology has been tremendous.In liver oncology alone,there has been concurrent technological innovation across the different adjunct fields and tiers of oncology related to hepatocellular carcinoma(HCC),progressing in quite an unprecedented rate.Significant improvements in our capacity to diagnose and prognosticate HCC with increasing sensitivity,specificity,and predictability is being witnessed.We now better understand that staging,treatment and prognostication cannot be determined on a static basis of tumor burden(i.e.,tumor size and number)alone and a“one size fits all”management.Careful individualized assessment is now mandatory in consideration of intra-and intertumoral heterogeneity and tumor biology in order to more precisely guide diagnostics and treatment options(1).

关键词： hepatocellular alone donor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Proton beam therapy for downstaging hepatocellular carcinoma with lobar portal vein tumor thrombosis to living donor liver transplantation

引用

Hepatobiliary Surgery and Nutrition 2023年第6期12卷 966-974页

作者： Chao-Long Chen Leona Bettina PDungca chee-chien yong Itsuko Chih-Yi Chen Yu-Fan Cheng Jen-Yu Cheng Yen-Yang Chen Liver Transplantation Center Department of SurgeryKaohsiung Chang Gung Memorial HospitalChang Gung University College of MedicineKaohsiung Liver Transplantation Center Department of Diagnostic RadiologyKaohsiung Chang Gung Memorial HospitalChang Gung University College of MedicineKaohsiung Liver Transplantation Center Department of Radiation OncologyKaohsiung Chang Gung Memorial HospitalChang Gung University College of MedicineKaohsiung Liver Transplantation Center Department of Hematology-OncologyKaohsiung Chang Gung Memorial HospitalChang Gung University College of MedicineKaohsiung

Introduction Liver transplantation(LT)is considered as the definitive standard treatment for hepatocellular carcinoma(HCC)with the advantage of addressing both malignancy and the underlying cirrhosis,thus,providing the best overall and recurrence-free survival.Unfortunately,only 20-25%of patients meet the eligibility criteria for LT.

关键词： Proton beam therapy(PBT) hepatocellular carcinoma(HCC) portal vein tumor thrombosis(PVTT) living donor liver transplantation(LDLT) downstaging therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

引用

Signal Transduction and Targeted Therapy 2024年第3期9卷 945-997页

作者： Jian Sheng Loh Wen Qi Mak Li Kar Stella Tan Chu Xin Ng Hong Hao Chan Shiau Hueh Yeow Jhi Biau Foo yong Sze Ong chee Wun How Kooi Yeong Khaw School of Pharmacy Monash University MalaysiaJalan Lagoon Selatan47500 Bandar SunwaySelangorMalaysia School of Pharmacy Faculty of Health&Medical SciencesTaylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia Digital Health&Medical Advancements Taylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia School of Biosciences Faculty of Health&Medical SciencesTaylor’s University1Jalan TaylorsSubang Jaya 47500 SelangorMalaysia UCL School of Pharmacy University College London29-39 Brunswick SquareLondon WC1N 1AXUK

The human gastrointestinal tract is populated with a diverse microbial community.The vast genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every aspect of human biology,including health maintenance,development,aging,and disease.The advent of new sequencing technologies and culture-independent methods has allowed researchers to move beyond correlative studies toward mechanistic explorations to shed light on microbiome–host interactions.Evidence has unveiled the bidirectional communication between the gut microbiome and the central nervous system,referred to as the“microbiota–gut–brain axis”.The microbiota–gut–brain axis represents an important regulator of glial functions,making it an actionable target to ameliorate the development and progression of neurodegenerative diseases.In this review,we discuss the mechanisms of the microbiota–gut–brain axis in neurodegenerative diseases.As the gut microbiome provides essential cues to microglia,astrocytes,and oligodendrocytes,we examine the communications between gut microbiota and these glial cells during healthy states and neurodegenerative diseases.Subsequently,we discuss the mechanisms of the microbiota–gut–brain axis in neurodegenerative diseases using a metabolite-centric approach,while also examining the role of gut microbiota-related neurotransmitters and gut hormones.Next,we examine the potential of targeting the intestinal barrier,blood–brain barrier,meninges,and peripheral immune system to counteract glial dysfunction in neurodegeneration.Finally,we conclude by assessing the pre-clinical and clinical evidence of probiotics,prebiotics,and fecal microbiota transplantation in neurodegenerative diseases.A thorough comprehension of the microbiota–gut–brain axis will foster the development of effective therapeutic interventions for the management of neurodegenerative diseases.

关键词： degenerative therapeutic diseases

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Anode surface engineering of zinc-ion batteries using tellurium nanobelt as a protective layer for enhancing energy storage performance

引用

Journal of Energy Chemistry 2024年第5期92卷 113-123页

作者： Soobeom Lee Yeonjin Je Boeun Seok Hyun Tae Kim yong-Ryun Jo Soong Ju Oh Byoungyong Im Dae Guen Kim Sang-Soo chee Geon-Hyoung An Department of Energy System Engineering Gyeongsang National UniversityJinju 52725Republic of Korea Nano Convergence Materials Center Korea Institute of Ceramic Engineering and Technology(KICET)Jinju 52851Republic of Korea Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea School of Materials Science and Engineering Gyeongsang National UniversityJinju 52828Republic of Korea GIST Advanced Insitute of Instrumental Analysis(GAIA) Electron Microscopy LaboratoryGwangju Institute of Science and TechnologyGwangju 61005Republic of Korea Center for Advanced Materials and Processing Institute for Advanced EngineeringYongin 17180Republic of Korea Department of Energy Engineering Gyeongsang National UniversityJinju 52725Republic of Korea

Over the years,zinc-ion batteries(ZIBs)have attracted attention as a promising next-generation energy storage technology because of their excellent safety,long cycling performance,eco-friendliness,and high-power density.However,issues,such as the corrosion and dissolution of the Zn anode,limited wet-tability,and lack of sufficient nucleation sites for Zn plating,have limited their practical application.The introduction of a protective layer comprising of tellurium(Te)nanobelts onto the surface of Zn anode has emerged as a promising approach to overcome these limitations and improve the electrochemical behav-ior by enhancing the safety and wettability of ZIBs,as well as providing numerous nucleation sites for Zn plating.In the presence of a Te-based protective layer,the energy power density of the surface-engineered Zn anode improved significantly(ranging from 310 to 144 W h kg^(-1),over a power density range of 270 to 1,800 W kg^(-1)),and the lifespan capability was extended.These results demonstrate that the proposed strategy of employing Te nanobelts as a protective layer holds great promise for enhancing the energy storage performance of zIBs,making them even more attractive as a viable energy storage solution forthefuture.

关键词： Zn ion battery Anode Protective layer Tellurium Nanobelt

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A primary hepatic neuroendocrine tumor disguised as hepatocellular carcinoma

引用

Hepatobiliary Surgery and Nutrition 2020年第2期9卷 263-266页

作者： Zhihao Li chee-chien yong Chao-Long Chen Liver Transplantation Center Department of SurgeryKaohsiung Chang Gung Memorial HospitalKaohsiung

In a 72-year-old female patient,a 2 cm large lesion over liver segment 7(S7)was incidentally diagnosed during a hepatitis C follow-up.The patient was asymptomatic and had an unremarkable physical examination.Her past ... 详细信息

关键词： arterial hypertension female liver

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Time-Domain Numerical Simulation for Free Motion Responses of Two Ships Advancing in Head Waves

引用

China Ocean Engineering 2024年第3期38卷 519-530页

作者： PAN Su-yong CHENG yong School of Naval Architecture and Ocean Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

The constant panel method within the framework of potential flow theory in the time domain is developed for solving the hydrodynamic interactions between two parallel ships with forward speed.When solving problems within a time domain framework,the free water surface needs to simultaneously satisfy both the kinematic and dynamic boundary conditions of the free water surface.This provides conditions for adding artificial damping layers.Using the Runge−Kutta method to solve equations related to time.An upwind differential scheme is used in the present method to deal with the convection terms on the free surface to prevent waves upstream.Through the comparison with the available experimental data and other numerical methods,the present method is proved to have good mesh convergence,and satisfactory results can be obtained.The constant panel method is applied to calculate the hydrodynamic interaction responses of two parallel ships advancing in head waves.Numerical simulations are conducted on the effects of forward speed,different longitudinal and lateral distances on the motion response of two modified Wigley ships in head waves.Then further investigations are conducted on the effects of different ship types on the motion response.

关键词： ship motions time domain simulation forward speed different distances wave loads

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Optimizing multi-parameter distributed fiber sensors:a hybrid Rayleigh-Brillouin-Raman System approach

引用

Light(Science & Applications) 2024年第3期13卷 393-395页

作者： Kwang yong Song Dept.of Physics Chung-Ang University84 Heukseok-roDongjak-guSeoul 06974Korea

An optimized single-end hybrid Rayleigh,Brillouin,and Raman distributed fiber sensing system has been developed for simultaneous measurement of multiple parameters.This system integrates 3-bit pulse coding for the Raman signal and the Brillouin amplification of the Rayleigh-backscattered signal,discriminating strain,temperature,and vibration using a single sensing fiber.

关键词： fiber Rayleigh signal

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Living donor liver transplantation for Barcelona clinic liver cancer (BCLC) intermediate-stage hepatocellular carcinoma

引用

Hepatobiliary Surgery and Nutrition 2023年第2期12卷 169-182页

作者： Ming Chao Tsai chee-chien yong Chih-Che Lin Wei-Chen Lee Chih-Chi Wang Chao-Hung Hung I-Hsuan Chen Yu-Fan Cheng Chang-Chun Hsiao Tsung-Hui Hu Chao-Long Chen Division of Hepato-Gastroenterology Department of Internal MedicineKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung School of Medicine College of MedicineNational Sun Yat-sen UniversityKaohsiung Liver Transplantation Center and Department of Surgery Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung Division of Liver and Transplantation Surgery Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan Liver Transplantation Center and Department of Diagnostic Radiology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of MedicineKaohsiung Graduate Institute of Clinical Medical Sciences College of MedicineChang Gung UniversityDivision of Pulmonary and Critical Care MedicineKaohsiung Chang Gung Memorial HospitalKaohsiung

Background:Barcelona clinic liver cancer(BCLC)stage B(intermediate stage)hepatocellular carcinoma(HCC)is highly heterogeneous;thus,identifying the most effective treatment for individual patients represents a significant clinical challenge.However,transarterial chemoembolization(TACE)is the only recommended treatment option.Therefore,we aimed to investigate the patient characteristics and outcomes of living donor liver transplantation(LDLT)for BCLC stage B HCC.Methods:A total of 516 patients with BCLC stage B HCC who underwent LDLT(n=104)or did not undergo LDLT(non-LDLT;n=412)between 2004 to 2018 were analyzed by propensity score matching(PSM;1:4)analysis.Factors influencing overall survival(OS)and recurrence were analyzed using Cox’s proportional hazards models.Results:Patients treated with LDLT achieved better OS than the non-LDLT group,including liver-and non-liver related survival(all P60 years(P=0.006),a neutrophil-lymphocyte ratio(NLR)>4(P=0.016)and>3 locoregional therapies(LRT)before LDLT(P60 years(P3 LRT before LDLT(P=0.001)were independent risk factors for OS.Using a combination of age,NLR,and LRT before liver transplantation(LT),the patients can be divided into low-risk(none of risk),intermediate-risk(one of risk),and high risk(more than two of risk)groups.There were significant differences in the cumulative HCC recurrence(P<0.001)and mortality(P<0.001)rates among the three groups.Conclusions:LDLT may represent a valuable therapeutic option for selected patients with BCLC stage B HCC.

关键词： Living donor liver transplantation(LDLT) Barcelona clinic liver cancer stage B(BCLC stage B) intermediate stage hepatocellular carcinoma(HCC)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Recent advances in multifunctional shape memory photonic crystals and practical applications

引用

Nano Research 2024年第1期17卷 79-96页

作者： yong Qi Shufen Zhang State Key Laboratory of Fine Chemicals Frontier Science Center for Smart MaterialsDalian University of TechnologyDalian 116024China

Shape memory photonic crystals(SMPCs)are smart composite materials with changeable structural color integrated by shape memory polymer and photonic crystals.SMPC can produce one or more temporary shapes through nanoscale deformation,memorizing current states.SMPC can be recovered to their original shapes or some intermediate states under external stimuli,accompanied by the variation of structural color.As porous carriers with built-in sensing properties,SMPCs promoted the interdisciplinary development of nanophotonic technology in materials science,environmental engineering,biomedicine,chemical engineering,and mechanics.Herein,the recent progress on multifunctional SMPCs and practical applications,including traditional and cold programmable SMPCs,is summarized and discussed.The primary concern is shape programming at the nanoscale that has demonstrated numerous attractive functions,including smart sensing,ink-free printing,solvent detection,reprogrammable gradient wetting,and controllable bubble transportation,under variations of the surface nanostructure.It aims to figure out the nanoscale shape memory effects on structural color conversion and additional performance,inspiring the fabrication of the next generation of SMPCs.Finally,perspectives on future research directions and applications are also presented.It is believed that multifunctional SMPCs are powerful nanophotonic tools for the interdisciplinary development of numerous disciplines in the future.

关键词： photonic crystal shape memory structural color cold programmable shape recovery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：