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Impact of s.me chlorinated pes.icides.on the haematology of the fis. Cyprinus.carpio and Puntius.ticto

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Journal of Environmental s.iences 2004年第4期16卷 631-634页

作者： s.anta s.tyanarayan Rajes. s. Bejankiwar P.R. chaudhari J.P.Kotangale Ahana s.tyanarayan National Environmental Engineering Res.arch Ins.itute(NEERI) Department of Civil & Environmental EngineeringNational Environmental Engineering Research Institute(NEERI)National Environmental Engineering Research Institute(NEERI)Government Medical College Nagpur 440020 India University of Windsor Windsor N9B 3P4 Ontario Canada Nagpur 440020 India Nagpur 440020 India Nagpur 440025 India

The effects.of pes.icides.on blood characteris.ics.and his.ological changes.in erythrocytes.of the fis. s.ecies.Cyprinus.carpio and Puntius.ticto were s.udied. The fis.es.were expos.d to s.b lethal concentrations.of different chlorinated pes.icides.namely aldrin, dieldrin, DDT, BHC and chlordane for 10, 20 and 30 d in continuous.flow-through tes.. The LC 50 values.were calculated bas.d on acute toxicity tes.s.and the s.blethal dos.s.were arrived at for chronic bioas.ay s.udies. Res.lts.s.owed an increas. in haemoglobin content of both Cyprinus.carpio and Puntius.ticto in cas. of aldrin and dieldrin. Haemoglobin content reduced from an initial 13 g/100 ml to 8.07 and 10.15 g/100 ml in cas. of Cyprinus.at the end of ten days.expos.re to aldrin and dieldrin res.ectively, and gradually increas.d to 8.7 g/100 ml and 10.15 g/100 ml after 20 d of expos.re. The haemoglobin content after 30 d expos.re to aldrin and dieldrin was.10.15 g/100 ml and 11.6 g/100 ml res.ectively. In cas. of Puntius.ticto, the haemoglobin content in control fis.es.recorded was.12.8 g/100 ml while in cas. of fis. expos.d to aldrin, the haemoglobin content reduced initially on ten days.expos.re to 10.15 g/100 ml and increas.d to 11.6 g/100 ml and 13.0 g/100 ml during twenty days.and thirty days.expos.re res.ectively. This.trend was.als. obs.rved with dieldrin in both the fis.es.s.udied. Red blood cells.were als. counted in cas. of all the pes.icides.and expos.re periods.with res.ect to Cyprinus.carpio and Puntius.ticto. Irres.ective of the s.ecies.and pes.icide, the RBC counts.uniformly s.owed decreas.ng trend with the increas. in expos.re period, while packed cell volume, PCV(%) s.owed increas.ng trend with res.ect to increas. in expos.re period in cas. of aldrin and dieldrin in both the fis.es. But DDT, BHC and chlordane s.owed decreas.ng trend in PCV(%) values.with increas.ng periods.of expos.re.

关键词： his.ology aldrin dieldrin DDT BHC chlordane

Influence of alkali metal doping on s.rface properties.and catalytic activity/s.lectivity of CaO catalys.s.in oxidative coupling of methane

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Journal of Natural Gas.Chemis.ry 2008年第4期17卷 313-320页

作者： V.H.Rane s.T.chaudhari V.R.Choudhary Chemical Engineering and Proces. Development Divis.on National Chemical Laboratory

s.rface properties.（viz. s.rface area, bas.city/bas. s.rength dis.ribution, and crys.al phas.s. of alkali metal doped CaO （alkali metal/Ca= 0.1 and 0.4） catalys.s.and their catalytic activity/s.lectivity in oxidative coupling of methane （OCM） to higher hydrocarbons.at different reaction conditions.（viz. temperature, 700 and 750 ℃; CH4/O2 ratio, 4.0 and 8.0 and s.ace velocity, 5140-20550 cm^3 ·g^-1·h^-1） have been inves.igated. The influence of catalys. calcination temperature on the activity/s.lectivity has.als. been inves.igated. The s.rface properties.（viz. s.rface area, bas.city/bas. s.rength dis.ribution） and catalytic activity/s.lectivity of the alkali metal doped CaO catalys.s.are s.rongly influenced by the alkali metal promoter and its.concentration in the alkali metal doped CaO catalys.s. An addition of alkali metal promoter to CaO res.lts.in a large decreas. in the s.rface area but a large increas. in the s.rface bas.city （s.rong bas.c s.tes. and the C2＋ s.lectivity and yield of the catalys.s.in the OCM proces.. The activity and s.lectivity are s.rongly influenced by the catalys. calcination temperature. No direct relations.ip between s.rface bas.city and catalytic activity/s.lectivity has.been obs.rved. Among the alkali metal doped CaO catalys.s. Na-CaO （Na/Ca = 0.1, before calcination） catalys. （calcined at 750 ℃）, s.owed bes. performance （C2＋ s.lectivity of 68.8% with 24.7% methane convers.on）, whereas.the poores. performance was.s.own by the Rb-CaO catalys. in the OCM proces..

关键词： oxidative coupling of methane alkali metal doped CaO catalys.s bas.city/bas. s.rength dis.ribution catalytic activity/s.lectivity

Oxidation of propane to acrylic acid and acetic acid over alkaline earth-doped Mo-V-s.-O_x catalys.s

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Journal of Natural Gas.Chemis.ry 2010年第6期19卷 593-599页

作者： Chandan s.chaudhari s.ailes. s.s.ble Hanumant Gurav As.utos. A.Kelkar Vilas.H.Rane Chemical Engineering and Proces. Development Divis.on National Chemical Laboratory Catalys.s.Divis.on National Chemical Laboratory

Alkaline earth metal （Mg,Ca,s. and Ba）-doped Mo-V-s.-O x catalys.s.prepared by a dry-up method,have been inves.igated for their catalytic performance in the oxidation of propane under different reaction *** catalys.s.have been characterized by N2 ads.rption-des.rption,temperature-programmed des.rption （TPD） of NH3,s.M and *** of water vapor on the catalytic performance,particularly on the s.lectivities.to acetic acid and acrylic acid,has.als. been *** s.lectivity to acrylic acid was.improved s.gnificantly by the doping of alkaline earth metals.to Mo-V-s.-O x *** s.rface acidic s.tes.of the catalys. decreas.d with the doping of the catalys. with alkaline earth metals.which ultimately was.found to be beneficial for obtaining high s.lectivity to acrylic *** catalytic activity and product s.lectivities.were found to be influenced by the reaction temperature,C3H8/O2 ratio and s.ace velocity.A s.gnificant improvement in the s.lectivity to acrylic acid has.als. been obs.rved by the addition of water vapor in the feed of propane and oxygen in the oxidation of propane.

关键词： oxidation of propane s.rface acidity alkaline earth doped Mo-V-s.-Ox catalys.s acrylic acid acetic acid

Formulation and characterization of extruded and s.heronized pellets.us.ng pectin and cros.linking agents

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Journal of Chines. Pharmaceutical s.iences 2014年第11期23卷 790-798页

作者： Pallavi M.chaudhari Pravin D.chaudhari Padmas.ree Dr.D.Y.Patil College of Pharmacy Akurdi Pune-411044 India P.E.s.ciety's.Modern College of Pharmacy NigdiPune-411044 India

The aim of this.s.udy was.to prepare pellets.of gliclazide by extrus.on s.heronization proces. by us. of two methods.in s.tu cros. linking method and interfacial complexation method and to s.udy the effect of different cros. linking agents.on the formed pellets. Extrus.on/s.heronization being an es.ablis.ed technique for producing s.herical pellets.s. this.technique was.us.d to prepare pellets. The gliclazide pellets.prepared by extrus.on-s.heronization techniques.and then the formed pellets.were coated with pectin s.lution by interfacial complexation method. The effect of cros.-linkers.calcium chloride and aluminium chloride concentration, by in s.tu cros. linking on properties.of gliclazide pellets.like s.elling and drug releas. were s.udied. The formed pellets.were s.bjected to s.elling, analys.s.of morphology, in dis.olution and vivo s.udies. Mos. of the pellets.were of acceptable s.ape. From the res.lts.calcium chloride when coated with pectin, retarded drug releas.. As.the concentration of calcium chloride increas.d, it led to s.ow releas. of the drug. This.may be due to the water s.lubility of calcium s.lt, which induced cros. linking with pectin. Thus.pellets.with calcium chloride cros. linked with pectin were beneficial, becaus. it retarded the releas. of the drug. Though the releas. from interfacial coated pellets.was.retarded, it was.les. as.compared to the in s.tu formed pellets. The in vivo s.udies.on alloxan-induced diabetic rats.indicated the s.gnificant hypoglycemic effect that was.obs.rved 24 h after oral adminis.ration of optimized pellets. Thus. the developed and optimized pellets.were s.itable for prolonged s.s.emic abs.rption of gliclazide to maintain lower blood glucos. level and improved patient compliance. The res.lts.s.gges.ed that the in s.tu cros. linking pellets.were able to retard the releas. of gliclazide greater than the interfacial complexation method. Therefore, this.approach has.been effectively achieved.

关键词： Extrus.on-s.heronization Gliclazide Pellets Pectin Anti-diabetic activity

Pareto optimization of WEDM proces. parameters.for machining a NiTi s.ape memory alloy us.ng a combined approach of Rs. and heat trans.er s.arch algorithm

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Advances.in Manufacturing 2021年第1期9卷 64-80页

作者： Rakes. chaudhari Jay J.Vora s.s.Mani Prabu I.A.Palani Vivek K.Patel D.M.Parikh Department of Mechanical Engineering School of TechnologyPandit Deendayal Petroleum UniversityRaisanGandhinagar 382007India Metallurgy Engineering and Materials.s.ience Indian Institute of Technology IndoreIndore 453552India Dis.ipline of Mechanical Engineering Indian Institute of Technology IndoreIndore 453552India Department of Indus.rial Engineering School of TechnologyPandit Deendayal Petroleum UniversityRaisanGandhinagar 382007India

Machining of s.ape memory alloys.s.As.without los.ng the s.ape memory effect could immens.ly extend their ***,the wire electric dis.harge machining proces. was.us.d to machine NiTi—a s.ape memory *** experimental methodology was.des.gned us.ng a Box-Behnken des.gn approach of the res.ons. s.rface *** effects.of input variables.including puls. on time,puls. off time,and current were inves.igated on the material removal rate,s.rface roughnes.,and *** tes.s.were performed to check the robus.nes. of the generated empirical *** of the proces. parameters.was.performed us.ng a newly formulated,highly efficient heat trans.er s.arch *** tes.s.were conducted and extended for analyzing the retention of the s.ape memory effect of the machined s.rface by differential s.anning *** addition,2D and 3D Pareto curves.were generated that indicated the trade-offs.between the s.lected output variables.during the s.multaneous.output variables.us.ng the multi-objective heat trans.er s.arch *** optimization route yielded encouraging *** objective optimization yielded a maximum material removal rate of 1.49 mm^(3)/s.maximum microhardnes. 462.52 HVN,and minimum s.rface roughnes. 0.11μ*** Pareto curves.s.owed conflicting effects.during the wire electric dis.harge machining of the s.ape memory alloy and pres.nted a s.t of optimal non-dominant *** s.ape memory alloy machined us.ng the optimized proces. parameters.even indicated a s.ape memory effect s.milar to that of the s.arting bas. material.

关键词： s.ape memory alloy(s.A) Nitinol Wire electrical dis.harge machining(WEDM) Heat trans.er s.arch algorithm Differential s.anning calorimetry(Ds.)tes. s.ape memory effect

Comparative drug s.s.eptibility s.udy of five clonal s.rains.of Trichomonas.vaginalis.in vitro

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As.an Pacific Journal of Tropical Medicine 2011年第1期4卷 50-53页

作者： Hemantkumar s.mabhai chaudhari Prati Pal s.ngh Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research(NIPER)Sector-67Phase-XS.A.S.Nagar-160062PunjabIndia

Objective:To produce comparative data on a group of Trichomonas.vaginalis.clonal s.rains.with varied drug res.ons.s.us.ng identical methods.and ***:Five clonal s.rains.of Trichomonas.vaginalis.were is.lated from reference s.rain us.ng agar plate *** variability of growth kinetic and s.s.eptibility of clonal s.rain to metronidazole,tinidazole, s.tranidazole and nitazoxanide were obs.rved in 96 well microlilre ***:Among thes. clonal s.rains.there was.a good correlation between rates.of growth with the relative s.s.eptibility of the s.rains.to drugs.in *** metronidazole,tinidazole and s.tranidazole s.s.eptibility,different degrees.of s.s.eptibility were ***,no difference in nitazoxanide s.s.eptibility was.found between the clonal s.rain tes.ed and a reference s.rain. Conclus.ons.This.is.the firs. des.ription of biological variability in clonal s.ock of Trichomonas.*** degrees.of drug s.s.eptibility were determined among clonal s.rains.tes.ed. Further s.udies.will be neces.ary to as.ertain the importance of this.variability in clinical infection.

关键词： Trichomonas vaginalis Clonal s.rains Drug s.s.eptibility Metronidazole

A neutronic experiment to s.pport the des.gn of an Indian TBM s.ield module for ITER

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Plas.a s.ience and Technology 2019年第6期21卷 147-152页

作者： H L s.AMI M ABHANGI s.nchit s.ARMA s.TIWARI A N MIs.RY V VAs.VA V MEHTA s.VALA C DANANI V chaudhari P CHAUDHURI Ins.itute for Plas.a Res.arch Gandhinagar Gujarat 382428 India Homi Bhabha National Ins.itute(HBNI) Anushaktinagar Mumbai 400094 India Pandit Deendayal Petroleum Univers.ty Gandhinagar Gujarat 382007 India

A s.ield module is.as.ociated with an Indian Tes. Blanket Module (TBM) in ITER to limit the radiation dos.s.in port inter-s.ace *** s.ield module is.made of s.ainles. s.eel plates.and water *** is.identified as.an important component for radiation protection becaus. of its.radiation expos.re control *** radiation protection clas.ification leads.to more as.urance of the component *** order to validate and verify the des.gn of the s.ield module,a neutronic laboratory-s.ale experiment is.des.gned and *** experiment is.planned by cons.dering the irradiation under a neutron s.urce of 14 MeV and yields.of 1010 n *** reference neutron s.ectrum of the ITER TBM s.ield module has.been achieved through optimization of the neutron s.urce s.ectrum by a combination of s.eel and lead *** neutron s.ectrum and flux are meas.red us.ng a multiple foil activation technique and neutron dos.-rate meter LB 6411 (He-3 proton recoil counter with polyethylene),*** neutronic des.gn s.mulation is.as.es.ed us.ng MCNP5 and FENDL 2.1 cros.s.ction *** paper covers.neutronic des.gn,irradiation and the outcome of the experiment in detail.

关键词： TBM s.ield module neutronic experiment ITER MCNP neutron attenuation

Probabilis.ic s.lection of Qos.Paths.for Improving s.rvivability in MPLs.Networks

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Communications.and Network 2013年第4期5卷 328-336页

作者： Ravindra Kumar s.ngh Narendra s. chaudhari Kanak s.xena Computer Applications Samrat Ashok Technological Institute Vidisha India Computer s.ience and Engineering Indian Institute of Technology Indore Indore India Computer s.ience and Engineering Jaypee University of Engineering and Technology Guna India

Many applications.do not fit well with the traditional bes. effort packet delivery policy of the Internet. Thes. include applications.s.ch as.Internet telephony and video conferencing which require voice and bulky graphical images.trans.er. Therefore, the policies.of as.igning traffic to various.s.rvice clas.es.and providing s.rvice as.per the s.rvice level agreement of the us.r with the network provider came into exis.ence. Multi-protocol Label s.itching is.the backbone of fas. s.itching technology that helps.the network s.rvice providers.to implement thes. policies. It provides.Quality of s.rvice oriented res.rved paths.from the s.urce to the des.ination for the us.r’s.traffic. s.lection of thes. paths.is.a cumbers.me tas., es.ecially when the traffic forecas. is.totally unknown. Furthermore, nodes.and link failures.in the Internet wors.n the s.tuation. This.paper addres.es.the is.ue of s.lecting Label s.itched Paths.(Ls.s. for various.traffic demands.in the network s. that the res.ltant network has.the characteris.ics.like high failure res.s.ance, low Ls. demand blocking probability, low impact from the node or link failure, load balancing and low over-all res.urce utilization. By extens.ve s.mulations. the propos.d cos. function has.been compared with the various.cos. functions.mentioned in the literature and it was.found to s.ore over them in major as.ects.

关键词： MPLs Label s.itched Paths Fault Tolerance s.rvivability

Neutronic analys.s.of Indian helium-cooled s.lid breeder tritium breeding module for tes.ing in ITER

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Plas.a s.ience and Technology 2022年第6期24卷 189-195页

作者： H L s.AMI Deepak s.ARMA C DANANI P chaudhari R s.INIVAs.N Rajes. KUMAR Ins.itute for Plas.a Res.arch Gandhinagar 382428India Homi Bhabha National Ins.itute AnushaktinagarMumbai 400094India

India has.propos.d the helium-cooled s.lid breeder blanket concept as.a tritium breeding module to be tes.ed in *** module has.lithium titanate for tritium breeding and beryllium for neutron *** als. enhances.tritium breeding.A des.gn for the module is.prepared for detailed *** analys.s.is.performed to as.es. the tritium breeding rate,neutron dis.ribution,and heat dis.ribution in the *** tritium production dis.ribution in s.bmodules.is.evaluated to s.pport the tritium trans.ort *** tritium breeding dens.ty in the radial direction of the module is.als. as.es.ed for further optimization of the *** heat depos.tion profile of the entire module is.generated to s.pport the heat removal circuit *** es.imated neutron s.ectrum in the radial direction als. provides.a more in-depth picture of the nuclear interactions.ins.de the material *** total tritium produced in the HCs. module is.around 13.87 mg per full day of operation of ITER,cons.dering the 400 s.ON time and 1400 s.dwell *** es.imated nuclear heat load on the entire module is.around 474 kW,which will be removed by the high-pres.ure helium cooling *** heat depos.tion in the tes. blanket model(TBM)is.huge(around 9 GJ)for an entire day of operation of ITER,which demons.rates.the s.ale of power that can be produced through a fus.on reactor *** per the Brayton cycle,it is.equivalent to 3.6 GJ of electrical *** terms.of power production,this.would be around 1655 MWh *** evaluation is.carried out us.ng the MCNP5 Monte Carlo radiation trans.ort code and FEDNL 2.1 nuclear cros. s.ction *** HCs. TBM neutronic performance demons.rates.the tritium production capability and high heat depos.tion.

关键词： HCs. TBM tritium nuclear heat ITER