检索结果-南通市图书馆

Dietary intake of advanced glycation endproducts(AGEs)and cancer risk across more than 20 anatomical sites:A multinational cohort study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cancer Communications 2022年第10期42卷 1041-1045页

作者： Reynalda Córdova Ana-lucia Mayén Viktoria Knaze Elom Kouassivi Aglago Casper Schalkwijk Karl-Heinz Wagner Kim Overvad Anne Tjønneland Cecilie Kyrø Verena Andrea Katzke charlotte le Cornet Matthias Bernd Schulze Anna Birukov Domenico Palli Sara Grioni Fabrizio Pasanisi Alberto Catalano Torkjel Manning Sandanger Inger Torhild Gram Guri Skeie Marta Crous-Bou Esther Molina-Montes Pilar Amiano Sandra Milena Colorado-Yohar Eva Ardanaz Isabel Drake Jonas Manjer Ingegerd Johansson Anders Esberg Aurora Perez-Cornago Elisabete Weiderpass Mazda Jenab Heinz Freisling Nutrition and Metabolism Branch International Agency for Research on Cancer(IARC-WHO)Lyon 69008France Department of Nutritional Sciences University of ViennaVienna 1090Austria Department of Internal Medicine Maastricht University Medical CentreMaastricht 6229the Netherlands Department of Public Health Aarhus UniversityAarhus 8000Denmark Danish Cancer Society Research Center Copenhagen 2100Denmark Division of Cancer Epidemiology German Cancer Research Center(DKFZ)Heidelberg 69120Germany Department of Molecular Epidemiology German Institute of Human Nutrition Potsdam-RehbrueckeNuthetal 14558Germany Institute of Nutritional Science University of PotsdamNuthetal 14558Germany Cancer Risk Factors and lifestyle Epidemiology Unit Institute for Cancer ResearchPrevention and Clinical Network(ISPRO)Florence 2-50139Italy Epidemiology and Prevention Unit Fondazione IRCCS Istituto Nazionale dei Tumori di Milano Milan 20133Italy Department of Clinical Medicine and Surgery University of Naples Federico IINaples 80138Italy Department of Clinical and Biological Sciences University of TurinTurin 1012Italy Department of Community Medicine UiT-the Arctic University of NorwayTromsø9037Norway Unit of Nutrition and Cancer Cancer Epidemiology Research ProgramCatalan Institute of Oncology(ICO)-Bellvitge Biomedical Research Institute(IDIBELL)L’Hospitalet de LlobregatBarcelona 08908Spain Department of Epidemiology Harvard T.H.Chan School of Public HealthBoston 02115USA Department of Nutrition and Food Science Faculty of PharmacyUniversity of GranadaGranada 18071Spain Ministry of Health of the Basque Government Sub Directorate for Public Health and Addictions of GipuzkoaSan Sebastian 20013Spain Biodonostia Health Research Institute Epidemiology of Chronic and Communicable Diseases GroupSan Sebastián 2014Spain Spanish Consortium for Research on Epidemiology and Public Health(CIBERESP) Instituto de Salud Carlos IIIMadrid 28029Spain Department of Epidemiology Murcia Regional Health CouncilIMIB-ArrixacaM

Dear Editor,In the European region,which shares 22.8%of the global cancer burden for 10%of the global population,there were around 4.4 million new cancer cases and 1.9 million deaths from cancer in 2020[1].The reasons for the high cancer incidence rates are complex;however,diet and dietary components are among the main contributors to cancer risk[2].In modern-day living,a growing proportion of people include in their diets ultra-processed *** of food processing and home-prepared foods are so-called dietary advanced glycation endproducts(AGEs),which are reactive metabolites emerging during the breakdown of reducing *** production is preponderant in dry high-heat processes(e.g.,baking,roasting);hence foods such as cakes,crisps,crackers,cereal products,meat and meat-derived products represent a major source of dietary AGEs[3].

关键词： dietary intake hence

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

领导力提升50个活动

legalon-SIl downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV

丛书名：培训大师的经典互动课

2004年

作者：露伊丝·B. 哈特（lois B. Hart）夏洛特·S. 韦斯曼（charlotte S. Waisman）汪开虎张东红译

本书内容包括：如何准备、怎样激发、怎样结束；回归真实的自我；以身作则；发挥最大潜能；以及培训方法术语表。

ISBN: (数字)7313037287

ISBN: (纸本)7313037287

本书内容包括：如何准备、怎样激发、怎样结束；回归真实的自我；以身作则；发挥最大潜能；以及培训方法术语表。

关键词：领导学

来源：汇雅图书（南通市图书馆... 评论

在线全文

汇雅图书（南通市图书馆）

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第13期17卷 1694-1700页

作者： Marjan Mehrab-Mohseni Hossein Sendi Nury Steuerwald Sriparna Ghosh laura W Schrum Herbert l Bonkovsky The liver-Biliary-Pancreatic Center Cannon Research Center Carolinas Medical Center Charlotte NC 28203 United States Department of Biology University of North Carolina at Charlotte Charlotte NC 28223 United States Department of Medicine University of North Carolina at Chapel Hill Chapel Hill NC United States

AIM: To determine the effect of legalon-SIl (lS) on hepatitis C virus (HCV) core and NS5A expression and on heme oxygenase-1 (HMOX-1) and its transcriptional regulators in human hepatoma cells expressing full length HCV genotype 1b. METHODS: CON1 cells were treated with 50 μmol/l or 200 μmol/l lS. Cells were harvested after 2, 6 and 24 h. HCV RNA and protein levels were determined by quantitative real-time polymerase chain reaction and Western blotting, respectively. RESUlTS: HCV RNA (core and NS5A regions) wasdecreased after 6 h with lS 200 μmol/l (P l/l lS decreased HCV RNA levels [core region (by 55% and 88%, respectively) and NS5A region (by 62% and 87%, respectively) after 24 h compared with vehicle (dimethyl sulphoxide) control (P larly HCV core and NS5A protein were decreased (by 85%, P ly) by lS 200 μmol/l. Bach1 and HMOX-1 RNA were also downregulated by lS treatment (P le Nrf2 protein was increased (P lUSION: Our results demonstrate that treatment with lS downregulates HCV core and NS5A expression in CON1 cells which express full length HCV genotype 1b, and suggests that lS may prove to be a valuable alternative or adjunctive therapy for the treatment of HCV infection.

关键词： Hepatitis Hepatitis C virus Silymarin Silybin Genotype Huh7.5 CON1

Virological and Molecular Profile of People living with the Human Immunodeficiency Virus Starting Dolutegravir Based Antiretroviral Treatment in Kinshasa, Democratic Republic of Congo

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

原发性免疫缺陷病患者肿瘤发生情况:美国免疫缺陷网络注册患者肿瘤发病率分析

World Journal of AIDS（艾滋病） 2023年第3期

作者： Berry I. Bongenya charlotte l. Tshinguta Marie-Thérèse A. S. Sombo Guy M. M. Bumoko Benoit O. Kabengele Gauthier K. Mesia Erick N. Kamangu

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

中华临床免疫和变态反应杂志 2018年第2期12卷 236-246页

作者： Paul C.Mayor Kevin H.Eng Kelly l.Singel Scott I.Abrams Kunle Odunsi Kirsten B.Moysich Ramsay Fuleihan Elizabeth Garabedian Patricia lugar Hans D.Ochs Francisco A.Bonilla Rebecca H.Buckley Kathleen E.Sullivan Zuhair K.Ballas charlotte Cunningham-Rundles Brahm H.Segal 白炜曾小峰中国医学科学院北京协和医学院北京协和医院风湿免疫科

研究背景评估了在美国免疫缺陷网络(USIDNET)注册的原发性免疫缺陷病(PIDDs)患者的总体和器官特异性肿瘤发病率,并与监测、流行病学和最终结果项目(SEER)数据库中经年龄校正的人群的肿瘤发病率进行比较。目的假设PIDD患者由于免疫功能受... 详细信息

研究背景评估了在美国免疫缺陷网络(USIDNET)注册的原发性免疫缺陷病(PIDDs)患者的总体和器官特异性肿瘤发病率,并与监测、流行病学和最终结果项目(SEER)数据库中经年龄校正的人群的肿瘤发病率进行比较。目的假设PIDD患者由于免疫功能受损,肿瘤发病率会增加。方法将2003年至2015年在USIDNET注册中心注册的PIDD (n=3658)患者的总体和器官特异性肿瘤发病率进行评估,并与SEER数据库中经年龄校正的人群发病率进行比较。结果与年龄相匹配的SEER人群相比,观察到PIDD患者罹患肿瘤的相对危险率为1. 42倍(P<0. 001)。PIDD的男性患癌症的风险是年龄校正的男性人群的1. 91倍(P<0. 001),而PIDD女性患者的总体肿瘤发病率与经年龄校正的女性人群相比并无差异。对SEER数据库中最常见的4个恶性肿瘤——肺癌、结肠癌、乳腺癌和前列腺癌的发病率进行分析,PIDD患者中这些肿瘤的发病没有显著增加。男性和女性PIDD患者的淋巴瘤发病率均显著增加(男性10倍,P<0. 001;女性8. 34倍,P<0. 001)。结论 PIDD患者的肿瘤发病率较高。在特定的PIDD人群中淋巴瘤发病率的增高是导致总体肿瘤发病率提高的主要原因,而常见的实体肿瘤的风险没有增加。这些数据表明免疫系统在预防特定肿瘤方面有一定的作用。

关键词：原发性免疫缺陷病普通变异性免疫缺陷病肿瘤白血病淋巴瘤美国免疫缺陷网络

Neurodevelopmental Outcome of Newborns Aged More than 34 Weeks Gestational Age Managed for Birth Asphyxia in Douala (Cameroon): A Single Hospital-Based Study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis

Open Journal of Pediatrics（儿科学期刊） 2023年第6期

作者： Diomède Noukeu Njinkui Dominique Enyama Yolande Djike Fokam Danie l.Nanga Mewolo Christelle Annick Ngo Kana Sylvain Raoul Simeni Njonnou charlotte Eposse Ekoube Arielle Annick Sime Tchouamo Paul Olivier Koki Ndombo Danièle-Christiane Kedy Koum

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2022年第7期13卷 631-643页

作者： Ian S Hong Allison J Rao Tyler l Carllee Joshua D Meade Daniel J Hurwit Gregory Scarola David P Trofa Shadley C Schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael Saltzman Department of Orthopedic Surgery Atrium Health Musculoskeletal InstituteCharlotteNC 28207United States Department of Sports Medicine Orthocarolina Research InstituteCharlotteNC 28207United States Department of Orthopedic Surgery Columbia University Irving Medical CenterNew York CityNY 10032United States Department of Orthopaedic Surgery Carolinas Medical CenterCharlotteNC 28207United States Department of Orthopedic Surgery OrthoCarolina Sports Medicine CenterCharlotteNC 28207United States

BACKGROUND Rotator cuff pathology is a very common source of shoulder ***,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar *** management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of *** To evaluate if a relationship exists between outcomes of RCR in the setting of *** This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between *** were stratified based on rotator cuff tear size and glenohumeral osteoarthritis *** were paired 1:1 with patients without glenohumeral *** included had a minimum two year *** of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were *** A total of 142 patients were *** number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without *** rotator cuff repair,both groups showed favorable patientreported *** Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis.

关键词： Rotator cuff repair Rotator cuff tear Glenohumeral osteoarthritis Shoulder Arthroscopic Outcomes

Hyperspectral Imaging Based on Compressive Sensing: Determining Cancer Margins in Human Pancreatic Tissue <i>ex Vivo</i>, a Pilot Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Medical Imaging 2021年第4期11卷 115-131页

作者： Joseph Peller Cobey l. McGinnis Kyle J. Thompson Imran Siddiqui John Martinie David A. Iannitti Susan R. Trammell Department of Physics and Optical Science University of North Carolina at Charlotte Charlotte USA Carolinas Medical Center Charlotte USA

Cancer is the second-leading cause of death in the United State and surgery remains the primary treatment for most solid mass tumors. However, accurately identifying tumor margins in real-time remains a challenge. In this study, the design and testing of hyperspectral imaging (HSI) system based on a single-pixel camera engine is discussed. The primary advantage of a single pixel architecture over traditional scanning HSI techniques is its high sensitivity and potential to function at low light levels. The objective for the imaging system described here is to detect changes in the reflectance spectra of tissue and to use these differences to delineate tumor margins. This paper presents the results of a 19-patient pilot study that assesses the ability of the HSI system to use reflectance imaging to delineate adenocarcinoma tumor margins in human pancreatic tissue imaged ex vivo. Pancreatic tissue excised during pancreatectomy was imaged immediately after being sent to the pathology lab. A pathologist sectioned the tissue and placed samples into standard tissue embedding cassettes. These tissue samples were then imaged using the HSI system. After imaging, the samples were returned to the pathologist for processing and analysis. The HSI was later compared to the histological analysis. The spectral angle mapping (SAM) and support vector machine (SVM) algorithms were used to classify pixels in the HSI images as healthy or unhealthy in order to delineate margins. Good agreement between margins determined via HSI (using both SAM and SVM) and histology/white light imaging was found.

关键词： Hyperspectral Imaging Cancer Detection Reflectance Spectroscopy Single Pixel Camera

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

野草如何创造空间:夏洛特花园

城市环境设计 2007年第3期 80-86页

作者：斯蒂格·l·安德森申申

我们都知道,草本植物会随着季节变换和风力大小在色彩和形态上产生变化。大多数人都有过这样的童年记忆:悠闲地躺在一片开阔的空地上,仰望碧蓝的天空,看朵朵白云飘浮而过,心中充满了诗情画意。对当今的景观设计师而言,再现这样的场景实... 详细信息

我们都知道,草本植物会随着季节变换和风力大小在色彩和形态上产生变化。大多数人都有过这样的童年记忆:悠闲地躺在一片开阔的空地上,仰望碧蓝的天空,看朵朵白云飘浮而过,心中充满了诗情画意。对当今的景观设计师而言,再现这样的场景实在太过普通,毫无新意,缺乏远见和挑战。现代社会在时间和空间概念上和以往完全不同,因此没有必要重复过去的场景。我们在夏洛特花园项目上就使用了与众不同的设计方法。这个花园位于哥本哈根一个住宅区的中央空地上,在这里,植物的外形、

关键词：花园哥本哈根住宅区园林丹麦夏洛特野草