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Oral Herbal Medicines for Psoriasis:A Review of Clinical Studies

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Chinese Journal of Integrative Medicine 2012年第3期18卷 172-178页

作者： Brian H.May Anthony l.ZHANG 卢传坚 charlie C.l.xue Traditional & Complementary Medicine Research Program Health Innovations Research Institute WHO Collaborating Centre for Traditional Medicine School of Health Sciences RMIT University Guangdong Provincial Academy of Chinese Medical Sciences and Guangdong Provincial Hospital of Chinese Medicine

Various forms of complementary and alternative medicine are used in *** these,herbal medicines are frequently used as systemic and/or topical interventions either as a replacement for or in conjunction with conventional *** benefit of such use is *** review is to provide an up-to-date review and discussion of the clinical evidence for the main kinds of herbal therapies for *** of the biomedical databases PubMed（including MEDlINE）, EMBASE and CINAHl were conducted in December 2011 which identified 32 clinical studies,all published in *** of these primarily tested topical herbal medicines and were thus *** 12 studies that evaluated systemic use of herbal medicines were included in the *** were case series studies and the other 8 were controlled *** terms of interventions,4 studies tested the systemic use of plant oils combined with marine oils and 8 studies tested multi-ingredient herbal *** clinical evidence for plant and animal derived fatty acids is inconclusive and any benefit appears to be *** the multi-herb formulations,benefits of oral herbal medicines were shown in several studies,however,a number of these studies are not controlled trials,a diversity of interventions are tested and there are methodological issues in the controlled *** conclusion,there is promising evidence in a number of the studies of multi-herb ***,well-designed,adequately powered studies with proper control interventions are needed to further determine the benefits of these *** addition,syndrome differentiation should be incorporated into trial design to ensure effective translation of findings from these studies into Chinese medicine clinical practice.

关键词： psoriasis herbal medicine complementary medicine traditional medicine clinical study review

A unified framework for isotropic meshing based on narrowband Euclidean distance transformation

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Computational Visual Media 2015年第3期1卷 239-251页

作者： Yuen-Shan leung Xiaoning Wang Ying He Yong-Jin liu charlie C.l.Wang School of Computer Engineering Nanyang Technological University Department of Computer Science and Technology Tsinghua University Department of Mechanical and Automation Engineering The Chinese University of Hong Kong

In this paper, we propose a simpleyet-effective method for isotropic meshing relying on Euclidean distance transformation based centroidal Voronoi tessellation(CVT). Our approach improves the performance and robustness of computing CVT on curved domains while simultaneously providing highquality output meshes. While conventional extrinsic methods compute CVTs in the entire volume bounded by the input model, we restrict the computation to a 3D shell of user-controlled thickness. Taking voxels which contain surface samples as sites, we compute the exact Euclidean distance transform on the GPU. Our algorithm is parallel and memory-efficient,and can construct the shell space for resolutions up to 20483 at interactive speed. The 3D centroidal Voronoi tessellation and restricted Voronoi diagrams are also computed efficiently on the GPU. Since the shell space can bridge holes and gaps smaller than a certain tolerance, and tolerate non-manifold edges and degenerate triangles, our algorithm can handle models with such defects, which typically cause conventional remeshing methods to fail. Our method can process implicit surfaces, polyhedral surfaces, and point clouds in a unified framework. Computational results show that our GPU-based isotropic meshing algorithm produces results comparable to state-ofthe-art techniques, but is significantly faster than conventional CPU-based implementations.

关键词： centroidal Voronoi tessellation(CVT) Euclidean distance transformation GPU isotropic meshing polygonal meshes point clouds implicit surfaces

Role of the gut microbiota in inflammatory bowel disease pathogenesis: What have we learnt in the past 10 years?

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World Journal of Gastroenterology 2014年第5期20卷 1192-1210页

作者： Georgina l Hold Megan Smith charlie Grange Euan Robert Watt Emad M El-Omar Indrani Mukhopadhya Gastro-intestinal Research Group Division of Applied Medicine University of Aberdeen Foresterhill

Our understanding of the microbial involvement in inflammatory bowel disease (IBD) pathogenesis has increased exponentially over the past decade. The development of newer molecular tools for the global assessment of the gut microbiome and the identification of nucleotide-binding oligomerization domain-containing protein 2 in 2001 and other susceptibility genes for Crohn’s disease in particular has led to better understanding of the aetiopathogenesis of IBD. The microbial studies have elaborated the normal composition of the gut microbiome and its perturbations in the setting of IBD. This altered microbiome or “dysbiosis” is a key player in the protracted course of inflammation in IBD. Numerous genome-wide association studies have identified further genes involved in gastrointestinal innate immunity (including polymorphisms in genes involved in autophagy: ATG16l1 and IGRM), which have helped elucidate the relationship of the local innate immunity with the adjacent luminal bacteria. These developments have also spurred the search for specific pathogens which may have a role in the metamorphosis of the gut microbiome from a symbiotic entity to a putative pathogenic one. Here we review advances in our understanding of microbial involvement in IBD pathogenesis over the past 10 years and offer insight into how this will shape our therapeutic management of the disease in the coming years.

关键词： Inflammatory bowel disease, Crohn’ s disease, Ulcerative colitis, Gut microbiota, Innate immune response, Probiotics, Prebiotics, Faecal transplant

Public Housing in U.S.A.

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世界建筑导报 1996年第2期 22-22页

作者： charlie q.l.xue

Housing problem was one of the prominent issues which would triggered revolution in the modem history, especially in 19th century Europe. This article is divided to three parts, policy of public housing, a historic vi... 详细信息

关键词：口口 Public Housing in U.S.A

Private Housing in U.S.A.

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世界建筑导报 1996年第2期 23-23页

作者： charlie q.l.xue

The United States is among the few countries which have the highest percentage of private housing ownership. This article is divided to three parts to tackle the various aspects of private housing: finance and market; design and construction. The figures of new construction house become the thermostat of American economy, and the home building is seen as the locomotive of US national economy. Measured by the housing price and annual income ratio (PIR)

关键词： than PIR In Private Housing in U.S.A

北京奥运建筑——“鸟巢”的城市影响及社会效应

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建筑师 2009年第4期 96-102页

作者：薛求理贾巍香港城市大学中央美术学院

国家体育场"鸟巢"是2008年北京奥运会的主体育场,承载了第29届奥运会、残奥会的开闭幕式以及田径、足球等众多赛事,已然成为北京北部区域的"新地标",同时它与奥运国际盛事的契合更使其超越了单纯的建筑意义,而成为一个"符号"象征着更多... 详细信息

国家体育场"鸟巢"是2008年北京奥运会的主体育场,承载了第29届奥运会、残奥会的开闭幕式以及田径、足球等众多赛事,已然成为北京北部区域的"新地标",同时它与奥运国际盛事的契合更使其超越了单纯的建筑意义,而成为一个"符号"象征着更多的内涵,引起了国内外广泛的关注。本文试图从"图符式建筑"的角度认知阅读"鸟巢",分析这一建筑事件作为新的中国"符号"对于城市以及整个社会有着如何的影响。文章主要从城市形象、社会效应和文化角度观察它的影响力,并试图透过这一典型事件对当代中国的"图符式地标"建筑的评价标准和发展趋势作一展望。

关键词：鸟巢图符城市社会奥运建筑

Traditional Chinese manual acupuncture for management of obesity: A systematic review

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World Journal of Meta-Analysis 2015年第5期3卷 206-214页

作者： Kang Xiao li Angela Weihong Yang charlie Cl xue George Binh lenon Traditional and Complementary Medicine Research Program Health Innovations Research Institute School of Health Sciences RMIT University

AIM： To evaluate the effectiveness and safety ofacupuncture for the treatment of obesity by reviewing currently available randomised controlled ***： This review followed the Cochrane Hand-book for Systematic Reviews of Interventions. Fifteen English and three Chinese databases were searched from their respective inceptions until July 2014. Key words used in the search consisted of acupuncture, needles, obesity, overweight, randomised trial and their synonyms. The risk of bias of included studies was assessed. The differences in effect size between acupuncture and control （including sham, no treatment, western medicine and dietary therapy/exercise） groups were compared using Cochrane Collaboration’s RevMan5.3 ***： Two thousand six hundred and twenty-one records were identifed; after full-text articles assessed for eligibility, 9 of them met inclusion criteria. Majority of included studies had unclear or high risk of bias across all domains. All included studies had high or unclear risk of bias in randomisation, blinding and outcome data. Meta-analysis showed that acupuncture was more effective for reducing body weight and body mass index than no treatment group. Manual acupuncture was also superior to dietary therapy alone for decreasingbody weight. With dietary therapy as co-intervention, combined acupuncture group achieved lower body mass index than combined sham acupuncture group or dietary therapy alone group at the end of treatment period. No severe adverse events from acupuncture group were reported from all included ***： Due to the poor quality of included studies the effectiveness of acupuncture cannot be concluded. Better-designed, large-scale, randomised, sham-controlled clinical trials with long-term follow-up are needed.

关键词： Acupuncture Obesity Weight loss Over-weight Body weight Body mass index Randomised clinical trial

Genotype variations in accumulation of cadmium and lead in celery （Apium graveolens l.） and screening for low Cd and Pb accumulative cultivars

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Frontiers of Environmental Science & Engineering 2013年第1期7卷 85-96页

作者： Kun ZHANG Jianbing WANG Zhongyi YANG Guorong XIN Jiangang YUAN Junliang XIN charlie HUANG State Key laboratory for Biocontrol School of Life Sciences Sun Yat-sen University Guangzhou 510275 China California Department of Fish and Game/OSPR/Scientific Division Sacramento CA 94244-2090 USA

To help reduce risks of heavy metal pollution, two pot experiments were conducted to investigate the variations, transfer potential, and stability of Cadmium (Cd) and lead (Pb) accumulations in celery ( l.) and to screen for low Cd and Pb accumulative cultivars. The maximum differences in shoot Cd concentration were 4.7-fold under low-Cd exposure and 3.3-fold under high-Cd exposure. These genotype variations in Cd accumulation are sufficiently large to help reduce Cd contamination risk in soil by using the low-Cd-Accumulative genotypes. Cd accumulation of the low-Cd-Accumulative genotypes is significantly positive correlated with Pb accumulation. Evidence obtained proves that Cd and Pb accumulations in celery are stable and genotype-dependent at the cultivar level. The presence of high-Pb contamination in soil promoted Cd accumulation in shoots of celery. Celery is considered a species with high risks in Cd pollution and low risks in Pb pollution. Among the tested cultivars, cv. Shuanggangkangbing (SGKB) had the lowest shoot Cd and Pb accumulating abilities, and thus is the most important material for breeding of pollution-safe cultivars (PSCs) to minimize Cd and Pb accumulations in celery.

关键词： cadmium (Cd) accumulation lead (Pb) accumulation celery genotype variation food safety

Clinical Observation on Chinese Herbal Medicine in Treatment of long-term Insomnia

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Chinese Journal of Integrative Medicine 2000年第2期6卷 122-126页

作者： David Wang charlie xue Noel lim Woei-Jia Jiang Jennifer R Jamison

Objective: To investigate the clinical efficacy of Serenity, an Australia Government listed Chinese herbal patent medicine, in the treatment of long-term ***: Adopting randomized double blind placebo controlled cross-over method, 19 volunteers participated were enrolled in this study for a period of 12 weeks. Each phase of the trial lasted for six weeks. No washout period was implemented. Assessment was based on the Vital Sign Test, Sleep Parameter questionnaire, leeds Sleep Evaluation questionnaire and the Side Effects questionnaire. Results: Serenity improved significantly the Overall Sleep Evaluation in the treated group, in comparing with that in the control group, Pl patent medicine,is effective for the clinical management of long-term insomnia.

关键词： insomnia sleep disorder Chinese herbal medicine Serenity