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Does Foreign Direct Investment Affect S0_(2) Emissions in the Yangtze river Delta?A Spatial Econometric Analysis

Chinese Geographical Science 2021年第3期31卷 400-412页

作者： GUO Zheng Sophia Shuang CHEN YAO Shimou Anna charles MKUMBO Key Laboratory of Watershed Geographic Sciences Nanjing Institute of Geography and LimnologyChinese Academy of SciencesNanjing 210008China University of Chinese Academy of Sciences Beijing 100049China School of Geography Nanjing University of Information Science&TechnologyNanjing 210000China Faculty of Science&Technology Teofilo Kisanji UniversityMbeya 999132Tanzania

As the major source of air pollution,sulfur dioxide(S0_(2))emissions have become the focus of global ***,existing studies rarely consider spatial effects when discussing the relationship between foreign direct investment(FDI)and S0_(2) *** study took the Yangtze river Delta as the research area and used the spatial panel data of 26 cities in this region for *** study investigated the spatial agglomeration effects and dynamics at work in FDI and S0_(2) emissions by using global and local measures of spatial ***,based on regression analysis using a results of traditional ordinary least squares(OLS)model and a spatial econometric model,the spatial Durbin model(SDM)with spatial-time effects was adopted to quantify the impact of FDI on S0_(2) emissions,so as to avoid the regression results bias caused by ignoring the spatial *** results revealed a significant spatial autocorrelation between FDI and S0_(2) emissions,both of which displayed obvious path dependence characteristics in their geographical distribution.A series of agglomeration regions were observed on the spatial *** estimation results of the SDM showed that FDI inflow promoted S0_(2) emissions,which supports the pollution haven *** findings of this study are significant in the prevention and control of air pollution in the Yangtze river Delta.

关键词： foreign direct investment(FDI) sulfur dioxide(S0_(2))emissions spatial Durbin model(SDM) spatial correlation Yangtze river Delta

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rabies in a postpandemic world:resilient reservoirs,redoubtable riposte,recurrent roadblocks,and resolute recidivism

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Animal Diseases 2023年第2期3卷 63-89页

作者： charles E.rupprecht Philip P.Mshelbwala r.Guy reeves Ivan V.Kuzmin College of Forestry Wildlife&EnvironmentCollege of Veterinary MedicineAuburn UniversityAuburnAL 36849USA School of Veterinary Science University of QueenslandGattonAustralia Department of Veterinary Medicine Faculty of Veterinary MedicineUniversity of AbujaAbujaNigeria Max Planck Institut Fur Evolutionsbiologie 24306 PlonGermany Department of Pathology University of Texas Medical BranchGalvestonTX 77555USA

rabies is an ancient *** centuries since Pasteur,fundamental progress occurred in virology,vaccinology,and diagnostics—and an understanding of pathobiology and epizootiology of rabies in testament to One Health—before common terminological ***,control,selective elimination,and even the unthinkable—occasional treatment—of this zoonosis dawned by the twenty-first ***,in contrast to smallpox and rinderpest,eradication is a wishful misnomer applied to rabies,particularly post-COVID-19 *** are *** encompasses bats and mesocarnivores,but other mammals represent a diverse spectrum of potential *** rabies virus is the classical member of the genus,other species of lyssaviruses also cause the *** reservoirs remain *** global,this viral encephalitis is untreatable and often *** with other neglected diseases,laboratory-based surveillance falls short of the notifiable ideal,especially in lower-and middleincome *** of actual burden defaults to a flux within broad health economic *** priorities,lack of defined,long-term international donors,and shrinking local champions challenge human prophylaxis and mass dog vaccination toward targets of 2030 for even canine rabies *** prevention,all licensed vaccines are delivered to the individual,whether parenteral or oral–essentially‘one and done’.Exploiting mammalian social behaviors,future‘spreadable vaccines’might increase the proportion of immunized hosts per unit ***,the release of replication-competent,genetically modified organisms selectively engineered to spread intentionally throughout a population raises significant biological,ethical,and regulatory issues in need of broader,transdisciplinary *** this rather curious idea will evolve toward actual unconventional prevention,control,or elimination in the near term remains *** the interim,more precise terminology an

关键词： Diagnosis Epidemiology Lyssavirus Neglected Tropical Diseases Pathogenesis Prophylaxis rabies Surveillance Vaccination Zoonosis

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Parvovirus B19 induced hepatic failure in an adult requiring liver transplantation

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World Journal of Gastroenterology 2009年第32期15卷 4067-4069页

作者： Darin S Krygier Urs P Steinbrecher Martin Petric Siegfried r Erb Stephen W Chung charles H Scudamore Andrzej K Buczkowski Eric M Yoshida Division of Gastroenterology Department of MedicineVancouver General HospitalVancouverBC V5Z 1M9Canada British Columbia Center for Disease Control VancouverBC V5Z 4R4Canada Department of Surgery Faculty of MedicineVancouver General HospitalVancouverBC V5Z 1M9Canada

Parvovirus B19 induced acute hepatitis and hepatic failure have been previously reported, mainly in children. Very few cases of parvovirus induced hepatic failure have been reported in adults and fewer still have required liver transplantation. We report the case of a 55-year-old immunocompetent woman who developed fulminant hepatic failure after acute infection with Parvovirus B19 who subsequently underwent orthotopic liver transplantation. This is believed to be the first reported case in the literature in which an adult patient with fulminant hepatic failure associated with acute parvovirus B19 infection and without hematologic abnormalities has been identified prior to undergoing liver transplantation. This case suggests that Parvovirus B19 induced liver disease can affect adults, can occur in the absence of hematologic abnormalities and can be severe enough to require liver transplantation.

关键词： Parvovirus B19 Fulminant hepatic failure Orthotopic liver transplant Fulminant hepatitis

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Optimizing neoadjuvant radiotherapy for resectable and borderline resectable pancreatic cancer using protons

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World Journal of Gastrointestinal Surgery 2019年第7期11卷 303-307页

作者： romaine charles Nichols Michael rutenberg Department of radiation Oncology University of Florida College of Medicine

Approximately 25%of patients diagnosed with pancreatic cancer present with non-metastatic resectable or borderline resectable ***,the cure rate for these“curable”patients is only in the range of 20%.Local-regional failure rates may exceed 50%after margin-negative,node-negative pancreatectomy,but up to 80%of resections are associated with regional lymph node or margin *** systemic drug therapy and chemotherapy may prevent or delay the appearance of distant metastases,it is unlikely to have a significant impact on local-regional disease *** radiotherapy would represent a rational intervention to improve local-regional *** barrier to preoperative radiotherapy is the concern that it could potentially complicate what is already a long and complicated *** the radiotherapy is delivered with X-rays(photons),the entire cylinder of the abdomen is irradiated;therefore,an operating surgeon may be reluctant to accept the associated risk of increased *** preoperative radiotherapy is delivered with protons,however,significant bowel and gastric tissue-sparing is achieved and clinical outcomes indicate that proton therapy does not increase the risk of operative complications nor extend the length of the procedure.

关键词： radiation oncology Pancreatic cancer Proton therapy

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Phase-field modeling of void evolution and swelling in materials under irradiation

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Science China(Physics,Mechanics & Astronomy) 2011年第5期54卷 856-865页

作者： HENAGEr charles H Jr KHALEEL Mohammad Pacific Northwest National Laboratory Richland WA 99352 USA

Void swelling is an important phenomenon observed in both nuclear fuels and cladding materials in operating nuclear reactors. In this work we develop a phase-field model to simulate void evolution and void volume change in irradiated materials. Important material processes, including the generation of defects such as vacancies and self-interstitials, their diffusion and annihilation, and void nucleation and evolution, have been taken into account in this model. The thermodynamic and kinetic properties, such as chemical free energy, interfacial energy, vacancy mobility, and annihilation rate of vacancies and interstitials, are expressed as a function of temperature and/or defect concentrations in a general manner. The model allows for parametric studies of critical void nucleus size, void growth kinetics, and void volume fraction evolutions. Our simulations demonstrated that void swelling displays a quasi-bell shape distribution with temperature often observed in experiments.

关键词： radiation void swelling vacancies interstitials phase-field model

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Staged liver resection for colorectal metastases:a valuable strategy or a waste of time?

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Hepatobiliary & Pancreatic Diseases International 2010年第6期9卷 600-604页

作者： raaj Chandra charles HC Pilgrim Val Usatoff The Alfred Hospital Upper Gastrointestinal/Hepatobiliary Surgery Unit

BACKGrOUND:The use of staged liver resections for colorectal metastases has been increasing in recent *** aim of this study was to determine the practices and outcomes of those surgeons attending the Australia and New Zealand Hepatic, Pancreatic and Biliary Association(ANZHPBA)meeting in 2008 who perform staged resections. METHODS:A questionnaire was sent to all members of the ANZHPBA and the international faculty who were invited to attend the annual meeting held in Coolum,Queensland, Australia in October 2008. rESULTS:There were 30 responses from 7 centres across the UK,Germany and ***-eight patients completed *** study population was predominantly male (n=20,67%),with an average age of 59.4 *** patients had bilobar disease.A right-sided first resection was planned in 39%of *** percent of patients underwent portal vein embolization prior to first resection.A second operation was performed at an average of 2.8 months from the first ***,50%(n=14)of patients eventually achieved a complete(r0)staged *** complications after the first resection were seen in 32%patients(n=9).Twenty- three patients underwent a second liver ***-five complications after the second resection were present in 57% (n=13). CONCLUSIONS:Two-stage liver resections are beneficial if both stages are completed and an r0 resection is achieved. While there is increased morbidity and mortality,we believe that staged liver resection for colorectal metastases is a valuable strategy in selected cases.

关键词： liver resection colorectal cancer liver metastases

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ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10(ABCC1O) are not primary resistance factors for cabazitaxel

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Chinese Journal of Cancer 2015年第3期34卷 115-120页

作者： rishil J Kathawala Yi-Jun Wang Suneet Shukla Yun-Kai Zhang Saeed Alqahtani Amal Kaddoumi Suresh V Ambudkar charles r Ashby Jr Zhe-Sheng Chen Department of Pharmaceutical Sciences College of Pharmacy and Health SciencesSt.John's University Laboratory of Cell Biology Center for Cancer ResearchNational Cancer InstituteNational Institutes of Health Department of Basic Pharmaceutical Sciences College of PharmacyThe University of Louisiana

Introduction:ATP-binding cassette subfamily B member 1(ABCB1) and subfamily C member 10(ABCCIO) proteins are efflux transporters that couple the energy derived from ATP hydrolysis to the translocation of toxic substances and chemotherapeutic drugs out of *** is a novel taxane that differs from paclitaxel by its lower affinity for ATP-binding cassette(ABC) ***:We determined the effects of cabazitaxel,a novel tubulin-binding taxane,and paclitaxel on paclitaxelresistant,ABCB1-overexpressing KB-C2 and LLC-MDr1-WT cells and paclitaxel-resistant,ABCC10-overexpressing HEK293/ABCC10 cells by calculating the degree of drug resistance and measuring ATPase activity of the ABCB1 ***:Decreased resistance to cabazitaxel compared with paclitaxel was observed in KB-C2,LLC-MDr1-WT,and HEK293/ABCC10 ***,cabazitaxel had low efficacy,whereas paclitaxel had high efficacy in stimulating the ATPase activity of ABCB1,indicating a direct interaction of both drugs with the ***:ABCB1 and ABCC10 are not primary resistance factors for cabazitaxel compared with paclitaxel,suggesting that cabazitaxel may have a low affinity for these efflux transporters.

关键词： ATP酶活性阻力家族会员亚科 HEK293 化疗药物紫杉醇

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利用EQuan^TM环境分析系统直接进样技术(20ml)LC-MS/MS分析饮用水样品中飞克级含量除草剂化合物

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环境化学 2009年第2期28卷 317-318页

作者： Jonathan r Beck charles Yang 赛默飞世尔科技公司美国加州圣河塞

随着人们对环境中除草剂以及其它化学药物残留的毒性作用关注程度的增加,实现对饮用水以及食物中这些物质的准确检测的需要显得更加迫切.

关键词：环境分析除草剂水样品饮用水进样技术高效液相色谱-串联质谱化合物系统

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图书情报科学的研究现状

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图书馆 1992年第3期 67-70页

作者：陈曙 charles r.McClure 上海师范大学图书馆 Syracuse大学图书情报学院

近年来,许多图书馆界的有识之士对图书情报学(简称LIS)产生了极大的兴趣。为此,他们期望吸引更多年富力强的图书情报专家,从中造就LIS研究的中坚骨干。这些人应当既重视基础研究,又不忽视应用研究,解决实际问题,从而推动学术工作的进展。

关键词：图书馆学情报学研究现状

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CLUSTErING PATENTS USING NON-EXHAUSTIVE OVErLAPS

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Journal of Systems Science and Systems Engineering 2010年第2期19卷 162-181页

作者： charles V. TrAPPEY Amy J.C. TrAPPEY Chun-Yi WU Department of Management Science National Chiao Tung University Taiwan China Department of Industrial Engineering & Management National Taipei University of Technology Taiwan China Department of lndustrial Engineering & Engineering Management National Tsing Hua University Taiwan China

Patent documents are unique external sources of information that reveal the core technology underlying new inventions. Patents also serve as a strategic data source that can be mined to discover state-of-the-art technical development and subsequently help guide r＆D investments. This research incorporates an ontology schema to extract and represent patent concepts. A clustering algorithm with non-exhaustive overlaps is proposed to overcome deficiencies with exhaustive clustering methods used in patent mining and technology discovery. The non-exhaustive clustering approach allows for the clustering of patent documents with overlapping technical findings and claims, a feature that enables the grouping of patents that define related key innovations. Legal advisors can use this approach to study potential cases of patent infringement or devise strategies to avoid litigation. The case study demonstrates the use of non-exhaustive overlaps algorithm by clustering US and Japan radio frequency identification （rFID） patents and by analyzing the legal implications of automated discovery of patent infringement.

关键词： Data mining patent analysis patent infringement non-exhaustive overlap clustering ontology schema

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