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浙江林业科技 1990年第1期10卷 77-78页

作者： charles r.blinn 陈德会

火炬松是美国栽植最广泛的松类树种。尽管原产地(阿帕拉契山脉以西)已接近田纳西州南部边界,但它仍是往北几百英里区域内的主要造林树种。

关键词：林木施肥火炬松叶色营养

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叶色和养分水平

广东林业科技 1990年第2期6卷 45-46页

作者： charles r.blinn 王光玉

火炬松在美国是种植最广的松树,尽管其天然分布区(阿巴拉契山脉的西部)接近田纳西州南部边界。

关键词：火炬松养分含量水平冬季叶色 Munsell色卡施肥计划偏相关系数内陆高海拔地区营养诊断

叶子颜色和营养水平——火炬松可作为森林土壤改良的指示树种

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甘肃林业科技 1988年第1期 61-63页

作者： charles r.blinn Edward r.Buckner 惠晓萍甘肃省林科所

火炬松是美国种植最广泛的松树,它的天然分布区虽然接近田纳西州南部边界的阿巴拉契亚山西部,但它还是向北几百英里森林区域内的主要造林树种。冬季,在火炬松天然分布区北部和更靠北的人工林中叶子普遍变黄,这种变黄在其它南部松林中通... 详细信息

火炬松是美国种植最广泛的松树,它的天然分布区虽然接近田纳西州南部边界的阿巴拉契亚山西部,但它还是向北几百英里森林区域内的主要造林树种。冬季,在火炬松天然分布区北部和更靠北的人工林中叶子普遍变黄,这种变黄在其它南部松林中通常与早期矿物质缺乏有关。火炬松林中的林地条件低劣,林业工作者认为在冬季这种现象很正常,因此,能否将火炬松冬季的叶子变黄做为国内高山地区火炬松营养含量的

关键词：色度火炬松北美刺果松营养水平树种

Function and dysfunction of GEMIN5:understanding a novel neurodevelopmental disorder

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Neural regeneration research 2024年第11期19卷 2377-2386页

作者： charles H.Nelson Udai B.Pandey Department of Pediatrics Division of Child NeurologyChildren’s Hospital of PittsburghUniversity of Pittsburgh Medical CenterPittsburghPAUSA Children’s Neuroscience Institute Children’s Hospital of PittsburghUniversity of Pittsburgh Medical CenterPittsburghPAUSA

The recent identification of a neurodevelopmental disorder with cerebellar atrophy and motor dysfunction(NEDCAM)has resulted in an increased interest in GEMIN5,a multifunction rNA-binding *** the largest member of the survival motor neuron complex,GEMIN5 plays a key role in the biogenesis of small nuclear ribonucleoproteins while also exhibiting translational regulatory functions as an independent *** many questions remain regarding both the pathogenesis and pathophysiology of this new disorder,considerable progress has been made in the brief time since its *** this review,we examine GEMIN5 within the context of NEDCAM,focusing on the structure,function,and expression of the protein specifically in regard to the disorder ***,we explore the current animal models of NEDCAM,as well as potential molecular pathways for treatment and future directions of *** review provides a comprehensive overview of recent advances in our understanding of this unique member of the survival motor neuron complex.

关键词： cerebellar atrophy GEMIN5 neurodevelopmental disorder neurological disease SMN complex

New evidence for the epigenetic regulation of skeletal stem cells

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Science Bulletin 2024年第13期69卷 2004-2006页

作者： Liming Zhao Jun Xiao charles K.F.Chan Institute for Stem Cell Biology and regenerative Medicine Stanford University School of MedicineStanford CA 94305USA Department of Surgery Division of Plastic and Reconstructive SurgeryStanford University School of MedicineStanford CA 94305USA Department of Orthopaedic Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Skeletal stem cells(SSCs)are crucial for skeletal development and regeneration,yet the epigenetic regulation of these cells remains poorly *** studies have delineated the epigenetic landscape across the developmental trajectory of SSCs,highlighting the involvement of Ptip in regulating SSC *** skeletal system undergoes dynamic remodeling throughout *** stem cells(SSCs),residing within the skeleton and lineage-restricted,serve as a cellular reserve to foster development and maintain skeletal *** categorized within the broader mesenchymal stromal/stem cells(MSCs).

关键词： skeletal involvement maintain

Otolaryngology residency program factors associated with female resident representation

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 7-11页

作者： Julia E.Canick James C.Campbell charles r.Woodard Lars J.Grimm Alissa M.Collins Duke University School of Medicine DurhamNorth CarolinaUSA Department of Head and Neck Surgery&Communication Sciences Duke University School of MedicineDurhamNorth CarolinaUSA Department of radiology Duke University School of MedicineDurhamNorth CarolinaUSA

Objective:Female representation in the field of otolaryngology is *** is the first point at which medical school graduates specialize in a chosen field and thus represents an opportunity to recruit and train more female *** study sought to identify program factors associated with greater female representation among resident ***:Departmental websites of all 124 otolaryngology residency programs in the United States and Puerto rico were examined for a list of *** programs with a resident roster available,the genders of residents,faculty,program directors,and chairpersons were *** and city population for each program was also recorded,as was female resident *** were compared using Pearson Chi‐squared univariate ***:1,632 residents and 2,605 faculty were included in the analysis of 109 *** median female resident representation was 40%.Programs with larger faculty sizes,more female faculty,and urban location were associated with an above‐median female resident *** with a larger residency cohort approached significance regarding above‐median female resident *** female faculty representation,program director gender,chairperson gender,and US region were not associated with variation in female resident ***:Greater female otolaryngology residency representation was associated with programs having an urban location and greater numbers of female and total *** was also likely that a larger resident cohort size may affect female resident *** proportions of female faculty,program director,and chairperson gender,as well as the US region,were not associated with variation in female resident gender representation.

关键词： gender program director recruitment residency training

COVID-19 vaccination produces exercise-responsive SArS-CoV-2 specific T-cells regardless of infection history

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Journal of Sport and Health Science 2024年第1期13卷 99-107页

作者： Kyle A.Smith Tiffany M.Zúñiga Forrest L.Baker Helena Batatinha charles r.Pedlar Shane C.Burgess Michael P.Gustafson Emmanuel Katsanis richard J.Simpson School of Nutritional Sciences and Wellness The University of ArizonaTucsonAZ 85721USA Department of Pediatrics The University of ArizonaTucsonAZ 85724USA Faculty of Sport Allied Health and Performance ScienceSt.Mary's UniversityTwickenham TW14SXUK Institute of Sport Exercise and Health University College LondonLondon WC1E 7HUUK Department of Animal and Comparative Biomedical Sciences The University of ArizonaTucsonAZ 85721USA The University of Arizona Cancer Center The University of ArizonaTucsonAZ 85719USA Laboratory Medicine and Pathology Mayo Clinic ArizonaPhoenixAZ 85054USA Department of Immunobiology The University of ArizonaTucsonAZ 85724USA Department of Medicine The University of ArizonaTucsonAZ 85724USA Department of Pathology The University of ArizonaTucsonAZ 85724USA

Background:The mobilization and redistribution of severe acute respiratory syndrome coronavirus 2(SArS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase immune surveillance and protect against severe coronavirus disease 2019(COVID-19).We sought to determine if COVID-19 vaccination would elicit exercise-responsive SArS-CoV-2 T-cells and transiently alter nAb ***:Eighteen healthy participants completed a 20-min bout of graded cycling exercise before and/or after receiving a COVID-19 *** major leukocyte subtypes were enumerated before,during,and after exercise by flow cytometry,and immune responses to SArS-CoV-2 were determined using whole blood peptide stimulation assays,T-cell receptor(TCr)-βsequencing,and SArS-CoV-2 nAb ***:COVID-19 vaccination had no effect on the mobilization or egress of major leukocyte subsets in response to intensity-controlled graded ***,non-infected participants had a significantly reduced mobilization of CD4+and CD8+naive T-cells,as well as CD4+central memory T-cells,after vaccination(synthetic immunity group);this was not seen after vaccination in those with prior SArS-CoV-2 infection(hybrid immunity group).Acute exercise after vaccination robustly mobilized SArS-CoV-2 specific T-cells to blood in an intensity-dependent *** groups mobilized T-cells that reacted to spike protein;however,only the hybrid immunity group mobilized T-cells that reacted to membrane and nucleocapsid *** increased significantly during exercise only in the hybrid immunity ***:These data indicate that acute exercise mobilizes SArS-CoV-2 specific T-cells that recognize spike protein and increases the redistribution of nAbs in individuals with hybrid immunity.

关键词： Anti-viral COVID-19 Exercise immunology SArS-CoV-2 T-Cells Vaccine

A Modified Transitional Korteweg-De Vries Equation: Posed in the Quarter Plane

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Journal of Applied Mathematics and Physics 2024年第7期12卷 2691-2701页

作者： charles Bu Department of Mathematics Wellesley College Wellesley MA USA

This paper is concerned with a modified transitional Korteweg-de Vries equation ut+f(t)u2ux+uxxx=0, (x,t)∈r+×r+with initial value u(x,0)=g(x)∈H4(r+)and inhomogeneous boundary value u(0,t)=Q(t)∈C2([ 0,∞ )). Under the conditions either 1) f(t)≤0, f′(t)≥0or 2) f(t)≤−αwhere α>0, we prove the existence of a unique global classical solution.

关键词： Modified Transitional KdV Equation Initial-Boundary Value Problem Semi-Group Local and Global Existence

An Analysis of Liberia’s Vulnerability to Climate Change in the Context of Least Developed Countries (LDCs): A review

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American Journal of Climate Change 2024年第2期13卷 230-250页

作者： charles Flomo Togbah State Key Laboratory of Pollution Control and resource reuse College of Environmental Science and Engineering Tongji University Shanghai China UNEP-Tongji Institute of Environment for Sustainable Development Shanghai China

Climate change is an alarming global challenge, particularly affecting the least developed countries (LDCs) including Liberia. These countries, located in regions prone to unpredictable temperature and precipitation changes, are facing significant challenges, particularly in climate-sensitive sectors such as mining and agriculture. LDCs need more resilience to adverse climate shocks but have limited capacity for adaptation compared to other developed and developing nations. This paper examines Liberia’s susceptibility to climate change as a least developed country, focusing on its exposure, sensitivity, and adaptive capacity. It provides an overview of LDCs and outlines the global distribution of carbon dioxide emissions. The paper also evaluates specific challenges that amplify Liberia’s vulnerability and constrain sustainable adaptation, providing insight into climate change’s existing and potential effects. The paper emphasizes the urgency of addressing climate impacts on Liberia and calls for concerted local and international efforts for effective and sustainable mitigation efforts. It provides recommendations for policy decisions and calls for further research on climate change mitigation and adaptation.

关键词： Least Developed Countries Liberia Climate Change Vulnerability Poverty Hunger Disease research and Development (r&D) Adaptation

The First Global Map of Atmospheric Ammonia(NH_(3)) as Observed by the HIrAS/FY-3D Satellite

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Advances in Atmospheric Sciences 2024年第3期41卷 379-390页

作者： Minqiang ZHOU Zhili DENG charles rOBErT Xingying ZHANG Lu ZHANG Yapeng WANG Chengli QI Pucai WANG Martine De MAZIÈrE Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100029China royal Belgian Institute for Space Aeronomy(BIrA-IASB) Brussels 1180Belgium National Satellite Meteorology Center China Meteorological AdministrationBeijing 100081China Department of Science&Technology and Climate Change China Meteorological AdministrationBeijing 100081China University of Chinese Academy of Sciences Beijing 100049China

Atmospheric ammonia(NH_(3)) is a chemically active trace gas that plays an important role in the atmospheric environment and climate change. Satellite remote sensing is a powerful technique to monitor NH_(3) concentration based on the absorption lines of NH_(3) in the thermal infrared region. In this study, we establish a retrieval algorithm to derive the NH_(3)column from the Hyperspectral Infrared Atmospheric Sounder(HIrAS) onboard the Chinese Feng Yun(FY)-3D satellite and present the first atmospheric NH_(3) column global map observed by the HIrAS instrument. The HIrAS observations can well capture NH_(3) hotspots around the world, e.g., India, West Africa, and East China, where large NH_(3) emissions exist. The HIrAS NH_(3) columns are also compared to the space-based Infrared Atmospheric Sounding Interferometer(IASI)measurements, and we find that the two instruments observe a consistent NH_(3) global distribution, with correlation coefficient(r) values of 0.28–0.73. Finally, some remaining issues about the HIrAS NH_(3) retrieval are discussed.

关键词： ammonia HIrAS/FY-3D satellite thermal-infrared observation remote sensing optimal estimation method