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Spatiotemporal continuum generation in polariton waveguides

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Light(Science & Applications) 2019年第1期8卷 1117-1127页

作者： Paul M.Walker charles e.whittaker Dmitry V.Skryabin emiliano Cancellieri Ben Royall Maksym Sich Ian Farrer David A.Ritchie Maurice S.Skolnick Dmitry N.Krizhanovskii Department of Physics and Astronomy University of SheffieldSheffield S37RHUK Department of Physics University of BathBath BA27AYUK ITMO University Kronverksky Avenue 49St.Petersburg 197101Russia Department of Physics Lancaster UniversityLancaster LA14YBUK Department of electronic and electrical engineering University of SheffieldSheffield S37HQUK Cavendish Laboratory University of CambridgeCambridge CB30HEUK

We demonstrate the generation of a spatiotemporal optical continuum in a highly nonlinear exciton–polariton waveguide using extremely low excitation powers(2-ps,100-W peak power pulses)and a submillimeter device suitable for integrated optics *** observe contributions from several mechanisms over a range of powers and demonstrate that the strong light–matter coupling significantly modifies the physics involved in all of *** experimental data are well understood in combination with theoretical *** results are applicable to a wide range of systems with linear coupling between nonlinear oscillators and particularly to emerging polariton devices that incorporate materials,such as gallium nitride and transition metal dichalcogenide monolayers that exhibit large light–matter coupling at room *** open the door to low-power experimental studies of spatiotemporal nonlinear optics in submillimeter waveguide devices.

关键词： millimeter waveguide optics

Robust Machine Learning Mapping of seMG Signals to Future Actuator Commands in Biomechatronic Devices

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Journal of Bionic engineering 2024年第1期21卷 270-287页

作者： Ali Nasr Sydney Bell Rachel L.whittaker Clark R.Dickerson John McPhee Systems Design engineering University of WaterlooWaterloo N2L 3G1Canada Kinesiology and Health Sciences University of WaterlooWaterloo N2L3G3Canada

A machine learning model for regression of interrupted Surface electromyography(seMG)signals to future control-oriented signals(e.g.,robot’s joint angle and assistive torque)of an active biomechatronic device for high-level myoelectric-based hierarchical control is proposed.A Recurrent Neural Network(RNN)was trained using output data,initially obtained from offline optimization of the biomechatronic(human–robot)device and shifted by the prediction *** input of the RNN consisted of interrupted seMG signals(to mimic signal disconnections)and previous kinematic signals of the assistive *** RNN with a 0.1-s prediction horizon could predict the control-oriented joint angle and assistive torque with 92%and 86.5%regression accuracy,respectively,for the test *** proposed approach permits a fast,predictive,and direct estimation of control-oriented signals instead of an iterative process that optimizes assistive torque in the inverse dynamic simulation of a multibody human–robot *** with these interrupted input signals significantly improves the regression accuracy in the case of seMG signal *** Robust Predictive Control-oriented Machine Learning(Robust-MuscleNeT)model can support volitional high-level myoelectric-based control of biomechatronic devices,such as exoskeletons,prostheses,and assistive/resistive *** work should study the application to prosthesis control as well as the repeatability of the high-level controller with electrode *** low-level hierarchical controller that manages the human–robot interaction,the assistance/resistance strategy,and the actuator coordination should also be studied.

关键词： Myoelectric-based control-Surface electromyography Machine learning Multibody system dynamics exoskeleton Bionic

Current devices,outcomes,and pain management considerations in penile implant surgery:an updated review of the literature

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Asian Journal of Andrology 2024年第4期26卷 335-343页

作者： Nirupama Ancha Maya eldin Tarah Woodle Sofia Gereta Krishna Hariprasad Imani Butler e charles Osterberg III Department of Surgery and Perioperative Care University of Texas at Austin Dell Medical SchoolAustinTX 78712USA Department of Urology Brooke Army Medical CenterSan AntonioTX 78234USA Department of Molecular Biosciences The University of Texas at AustinAustinTX 78712USA.

Penile prosthesis surgery is a definitive treatment for erectile dysfunction(eD).The two categories of penile prosthesis are endorsed by professional guidelines,inflatable penile prosthesis(IPP)and malleable penile prosthesis(MPP).each modality of penile prosthesis offers distinct advantages and incorporates specific design features,allowing for personalized device selection that aligns with individual needs and *** the overall complication rate of penile implant surgery remains low,surgeons should maintain a high index of suspicion for complications in the perioperative time *** analgesic regimens including nerve blocks and narcotic-free pathways should be administered to manage perioperative ***,the high patient satisfaction after penile prosthesis surgery underscores the success of this eD treatment option.

关键词： erectile dysfunction penile implant penile prosthesis

Governance in the exploration of global and regional determinants of ICT development

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International Journal of Innovation Studies 2024年第2期8卷 132-153页

作者： charles S.Saba Simplice A.Asongu Nicholas Ngepah Yolande e.Ngoungou School of economics College of Business and EconomicsUniversity of JohannesburgJohannesburgSouth Africa Department of econornic&Data Science New Uzbekistan University54 Mustaili AvenueTashkent100007Uzbekistan University of Yaounde 2 SoaCameroon

The present study assesses how governance affects information and communication technology(IcT)at the global level contingent on macroeconomic policy factors such as trade,foreign direct investment(FDI),manufacturing value added,and agricultural value *** study focuses on 183 countries from 2003 to 2021,and the empirical evidence is based on the generalized method of moments(GMM).The following main findings are *** the full sample,governance unconditionally promotes ICT development,while trade openness(industrial added value)moderates governance to promote(dampen)ICT *** sub-Saharan Africa,only trade openness effectively moderates governance to induce an overall positive effect on ICT,while in the Middle east and North Africa(MeNA)region,all policy variables moderate governance for an overall positive incidence on ICT sector *** findings for the MeNA region are confirmed in the europe and Central Asia(eCA)region,with the exception of the moderating role of industrial added value,which engenders an overall negative *** the east and South Asia and the Pacific(eSAP)countries,one overall positive incidence is apparent in the role of trade openness,while net negative effects are established from the moderating roles of industrial added value and agricultural added *** the American sub-sample,a positive(negative)net effect is apparent from the role of industrial added value(trade)in moderating the incidence of gover-nance on ICT sector ***,policy implications are discussed.

关键词： ICT Governance Trade FDI Industry Agriculture

Three-dimensional numerical analysis of plant-soil hydraulic interactions on pore water pressure of vegetated slope under different rainfall patterns

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Journal of Rock Mechanics and Geotechnical engineering 2024年第9期16卷 3696-3706页

作者： Haowen Guo charles Wang Wai Ng Qi Zhang Department of Civil and environmental engineering The Hong Kong University of Science and TechnologyHong KongChina

Understanding the pore water pressure distribution in unsaturated soil is crucial in predicting shallow landslides triggered by rainfall,mainly when dealing with different temporal patterns of rainfall ***,the hydrological response of vegetated slopes,especially three-dimensional(3D)slopes covered with shrubs,under different rainfall patterns remains unclear and requires further *** address this issue,this study adopts a novel 3D numerical model for simulating hydraulic interactions between the root system of the shrub and the surrounding *** series of numerical parametric studies are conducted to investigate the influences of slope inclination,rainfall pattern and rainfall *** rainfall patterns(advanced,bimodal,delayed,and uniform)and two rainfall durations(4-h intense and 168-h mild rainfall)are considered to study the hydrological response of the *** computed results show that 17%higher transpiration-induced suction is found for a steeper slope,which remains even after a short,intense rainfall with a 100-year return *** extreme rainfalls with advanced(PA),bimodal(PB)and uniform(PU)rainfall patterns need to be considered for the short rainfall duration(4 h),while the delayed(PD)and uniform(PU)rainfall patterns are highly recommended for long rainfall durations(168 h).The presence of plants can improve slope stability markedly under extreme rainfall with a short duration(4 h).For the long duration(168 h),the benefit of the plant in preserving pore-water pressure(PWP)and slope stability may not be sufficient.

关键词： Root-soil interactions Rainfall patterns Slope stability Three-dimensional(3D)

Metabolic reprogramming of the inflammatory response in the nervous system:the crossover between inflammation and metabolism

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Neural Regeneration Research 2024年第10期19卷 2189-2201页

作者： Jesus Amo-Aparicio charles A.Dinarello Ruben Lopez-Vales Department of Medicine University of ColoradoAuroraCOUSA Institute of Neurosciences and Department Cell BiologyPhysiology and ImmunologyUniversitat Autònoma de BarcelonaBellaterraSpain Centro de Investigación Biomédica en Red sobre enfermedades Neurodegenerativas(CIBeRNeD) Instituto de Salud Carlos ⅢSpain

Metabolism is a fundamental process by which biochemicals are broken down to produce energy(catabolism) or used to build macromolecules(anabolism). Metabolism has received renewed attention as a mechanism that generates molecules that modulate multiple cellular responses. This was first identified in cancer cells as the Warburg effect, but it is also present in immunocompetent cells. Studies have revealed a bidirectional influence of cellular metabolism and immune cell function, highlighting the significance of metabolic reprogramming in immune cell activation and effector functions. Metabolic processes such as glycolysis, oxidative phosphorylation, and fatty acid oxidation have been shown to undergo dynamic changes during immune cell response, facilitating the energetic and biosynthetic demands. This review aims to provide a better understanding of the metabolic reprogramming that occurs in different immune cells upon activation, with a special focus on central nervous system disorders. Understanding the metabolic changes of the immune response not only provides insights into the fundamental mechanisms that regulate immune cell function but also opens new approaches for therapeutic strategies aimed at manipulating the immune system.

关键词： central nervous system fatty acid oxidation glycolysis inflammation macrophage metabolism microglia neurodegeneration oxidative phosphorylation

Handwriting Analysis Based on Belief of Targeted Individual Supporting Insider Threat Detection

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Journal of Information Security 2024年第3期15卷 308-319页

作者： Jason Slaughter Carole e. Chaski Kellep charles Center for Cybersecurity Research and Analysis (CCRA) Capitol Technology University Laurel United States

The Unintentional Insider Threat (UIT) concept highlights that insider threats might not always stem from malicious intent and can occur across various domains. This research examines how individuals with medical or psychological issues might unintentionally become insider threats due to their perception of being targeted. Insights from the survey A Survey of Unintentional Medical Insider Threat Category indicate that such perceptions can be linked to underlying health conditions. The study emotion Analysis Based on Belief of Targeted Individual Supporting Insider Threat Detection reveals that anger is a common emotion among these individuals. The findings suggest that UITs are often linked to medical or psychological issues, with anger being prevalent. To mitigate these risks, it is recommended that Insider Threat programs integrate expertise from medicine, psychology, and cybersecurity. Additionally, handwriting analysis is proposed as a potential tool for detecting insider threats, reflecting the evolving nature of threat assessment methodologies.

关键词： Insider Threat Detection Targeted Medical

Modelling the water diversion of a sustainable cover system under humid climates

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Journal of Rock Mechanics and Geotechnical engineering 2024年第7期16卷 2429-2440页

作者： Haowen Guo charles Wang Wai Ng Qi Zhang Chuanxiang Qu Liwen Hu Shenzhen Research Institute of Hong Kong University of Science and Technology Shenzhen518057China Department of Civil and environmental engineering The Hong Kong University of Science and TechnologyHong Kong SAR999077China CCCC Fourth Harbor engineering Institute Co. LtdGuangzhou510230China

extreme rainfall significantly threatens the safety of the landfill cover system,especially under humid *** study aims to provide design recommendations for a sustainable landfill cover system consisting of a low-permeability soil layer underlying a two-layer capillary barrier for humid ***,the numerical back-analysis was conducted for verification against a series of flume model ***,a parametric study was performed to investigate the effects of inclination angle,particle size and layer thickness on the lateral diversion length(DL)of the three-layer cover system under the 100-year return period rainfall of humid *** results show that the water lateral DL of the cover system can be greatly enhanced by increasing the inclination angle from 3°to 18°.Moreover,the bottom layer of the cover system with a coarser d10 was more susceptible to the impact of the heavy rainfall,while this can be alleviated by increasing the thickness of the bottom layer.A dimensionless number,defined as the ratio of thickness and d_(10) of the bottom layer,is proposed for designing lateral diversion of the three-layer cover system under humid *** preserve the maximum DL,it is suggested that the proposed dimensionless number should be larger than 95 and 110 for the design of rainfall events with 50-year and 100-year return periods for humid climates,respectively.

关键词： Unsaturated soil Recycling Construction waste Three-layer landfill cover Water infiltration

Bulk geochemistry,Rb-Sr,Sm-Nd,and stable O-H isotope systematics of the Metzimevin high-grade iron ore deposit,Mbalam iron ore district,southern Cameroon

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Acta Geochimica 2024年第4期43卷 677-706页

作者： Samndong Cyril Tufoin Cheo emmanuel Suh Tabod charles Tabod George Lemewihbwen Ngiamte Department of Geology Mining and Environmental ScienceThe University of BamendaB.P.39BambiliNorth West RegionCameroon economic Geology Unit Department of GeologyUniversity of BueaP.O.63BueaSouth West RegionCameroon Department of Physics Faculty of ScienceThe University of BamendaB.P.39BambiliNorth West RegionCameroon Department of Geology Pan-African University Life and Earth Sciences Institute(PAULESI)University of IbadanIbadanNigeria

Bulk geochemistry,Sr,Nd,and O-H isotope systematics are reported for the first time on banded iron formation(BIF)-hosted high-grade iron ore at the northwestern segment of Congo Craton(CC).Located in Mbalam iron ore district,Southern Cameroon,Metzimevin iron ore deposit is a hematite-magnetite BIF system,dominated by SiO_(2)+Fe_(2)O_(3)(97.1 to 99.84 wt%),with low concentrations of clastic elements e.g.,Al_(2)O_(3),TiO_(2),and HFSe,depicting a nearly pure chemical *** Ree+Y signature of the iron deposit displays strong positive eu anomaly,strong negative Ce anomaly,and chondritic to superchondritic Y/Ho ratios,suggestive of formation by mixed seawater-high temperature hydrothermal fluids in oxidising ***^(87)Sr/^(86)Sr ratios of the BIF are higher than the maximum^(87)Sr/^(86)Sr evolution curves for all Archean reservoirs(bulk silicate earth,Archean crust and Archean seawater),indicating involvement of continentally-derived components during BIF formation and ***Ɛ_(Nd)(t)(+2.26 to+3.77)and Nd model age indicate that chemical constituents for the BIF were derived from undifferentiated crustal source,between 3.002 and 2.88 *** variable and diverse O and H isotope data(−1.9‰to 17.3‰and−57‰to 136‰respectively)indicate that the Metzimevin iron ore formed initially from magmatic plumes and later enriched by magmatic-metamorphic-modified meteoric *** balance calculations indicate mineralisation by combined leaching and precipitation,with an average iron enrichment factor of>2.67 and SiO_(2)depletion factor of>*** is associated with an overall volume reduction of 28.27%,reflecting net leaching and volume collapse of the BIF protholith.

关键词： Bulk geochemistry Rb-Sr Sm-Nd Mitzimevin High-grade iron ore