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禽安卡拉病毒的鉴定和主要结构蛋白基因分子特征分析

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中国兽医学报 2018年第5期38卷 895-899,916页

作者：常超越张召兴张志强贾青辉张建文李蕴玉吴同垒李佩国河北科技师范学院河北省预防兽医学重点实验室

安卡拉病毒属禽腺病毒C群Ⅳ血清型，临床上以引起患病鸡心包积液和肝炎为典型病理变化，发病急，死亡快，对养禽业造成巨大的经济损失。2016年5月秦皇岛市昌黎县某养鸡场养殖肉鸡大量死亡，死亡率高达80％，剖检见典型的心包积液、肝脏... 详细信息

安卡拉病毒属禽腺病毒C群Ⅳ血清型，临床上以引起患病鸡心包积液和肝炎为典型病理变化，发病急，死亡快，对养禽业造成巨大的经济损失。2016年5月秦皇岛市昌黎县某养鸡场养殖肉鸡大量死亡，死亡率高达80％，剖检见典型的心包积液、肝脏坏死和肾脏肿大，结合PCR鉴定、鸡胚和雏鸡接种试验，以及电镜观察，证明病原为安卡拉病毒，并命名为FAV-4QHD；通过对病毒主要结构蛋白Hexon、Penton、Fiber1和Fiber2基因测序和构建系统发育树发现，FAV-4 QHD与近几年的国内分离株亲缘关系最近，与FAV-4标准株0N1和国外分离株差异较大。研究结果为进一步分析安卡拉病毒毒力增强机制奠定基础。

关键词：禽安卡拉病毒结构蛋白分子特征

Tunable polarization-drived superior energy storage performance in PbZrO_(3) thin films

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Journal of Advanced Ceramics 2023年第5期12卷 930-942页

作者： Tiandong zhang Zhuangzhuang Shi chao Yin Changhai zhang yue zhang Yongquan zhang Qingguo Chen Qingguo Chi Key Laboratory of Engineering Dielectrics and Its Application Ministry of EducationHarbin University of Science and TechnologyHarbin 150080China Department of Materials Science and Engineering Korea Advanced Institute of Science and TechnologyDaejeon 305-701Republic of Korea

Antiferroelectric PbZrO_(3)(AFE PZO)films have great potential to be used as the energy storage dielectrics due to the unique electric field(E)-induced phase transition ***,the phase transition process always accompanies a polarization(P)hysteresis effect that induces the large energy loss(Wloss)and lowers the breakdown strength(EBDS),leading to the inferior energy storage density(Wrec)as well as low *** this work,the synergistic strategies by doping smaller ions of Li^(+)–Al^(3+)to substitute Pb2+and lowering the annealing temperature(T)from 700 to 550℃are proposed to change the microstructures and tune the polarization characters of PZO films,except to dramatically improve the energy storage *** prepared Pb_((1−x))(Li_(0.5)Al_(0.5))_(x)ZrO_(3)(P_((1−x))(L_(0.5)A_(0.5))_(x)ZO)films exhibit ferroelectric(FE)-like rather than AFE character once the doping content of Li^(+)–Al^(3+)ions reaches 6 mol%,accompanying a significant improvement of W_(rec) of 49.09 J/cm^(3),but the energy storage efficiency(η)is only 47.94%due to the long-correlation of FE ***,the low-temperature annealing is carried out to reduce the crystalline degree and the P loss.P_(0.94)(L_(0.5)A_(0.5))_(0.06)ZO films annealed at 550℃deliver a linear-like polarization behavior rather than FE-like behavior annealed at 700℃,and the lowered remanent polarization(P_(r))as well as improved E_(BDS)(4814 kV/cm)results in the superior Wrec of 58.7 J/cm^(3) and efficiency of 79.16%,simultaneously possessing excellent frequency and temperature stability and good electric fatigue tolerance.

关键词： lead zirconate ionic pair polarization breakdown strength energy storage

Accounting for Polychromatic Light in Virtual Shack-Hartmann Wavefront Sensing

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Photonic Sensors 2023年第3期13卷 8-22页

作者： Xian yue Yaliang YANG Hao DAI Shen CHEN chao GENG Yudong zhang Key Laboratory of Adaptive Optics Chinese Academy of SciencesChengdu 610209China Institute of Optics and Electronics Chinese Academy of SciencesChengdu 610209China University of Chinese Academy of Sciences Beijing 100049China

Virtual Shack-Hartmann wavefront sensing(vSHWS)has some significant advantages and is promising for aberration measurement in the field of biomedical optical *** illumination sources used in vSHWS are almost broadband,but are treated as monochromatic sources(only using center wavelength)in current data processing,which may cause *** work proposed a data processing method to take into account the multiple wavelengths of the broadband spectrum,named multiple-wavelength centroid-weighting *** feasibility was demonstrated through a series of simulations.A wavefront generated with a set of statistical human ocular aberrations was used as the target wavefront to evaluate the performance of the proposed and current *** results showed that their performance was very close when used for the symmetrical,but the wavefront error of the proposed method was much smaller than that of the current method when used for the asymmetrical spectrum,especially for the broader *** results were also validated by using 20 sets of clinical human ocular aberrations including normal and diseased *** proposed method and the obtained conclusions have important implications for the application of vSHWS.

关键词： Wavefront sensing aberration measurement numerical wavefront processing Shack-Hartmann wavefront sensing broadband spectral source

基于深度子空间学习和数据增强的滚动轴承故障诊断方法

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光电子·激光 2025年第1期36卷 69-76页

作者：张帅帅张超王肖锋天津理工大学天津市先进机电系统设计与智能控制重点实验室彼合彼方机器人(天津)有限公司天津理工大学机电工程国家级实验教学示范中心

主成分分析网络（principal component analysis network, PCANet）作为一种基于深度子空间学习框架的网络模型，在多个应用领域展现出卓越的性能。然而，在滚动轴承故障诊断方面，PCANet算法存在无法准确反映数据完整结构信息、鲁棒性... 详细信息

主成分分析网络（principal component analysis network, PCANet）作为一种基于深度子空间学习框架的网络模型，在多个应用领域展现出卓越的性能。然而，在滚动轴承故障诊断方面，PCANet算法存在无法准确反映数据完整结构信息、鲁棒性差以及泛化能力较弱等问题。本文针对这些问题，提出了一种基于PCANet算法和数据增强的滚动轴承故障诊断方法。该方法利用L2,1范数学习滚动轴承振动信号的频域稀疏结构，从而抑制噪声数据，提高模型鲁棒性。此外，通过数据增强处理，不同类别的训练样本之间的差异性也得到显著增加，从而提高了模型的泛化能力。最后，实验结果表明，该方法明显提高了PCANet模型的鲁棒性和泛化能力，能够准确识别不同类型的滚动轴承故障。

关键词：滚动轴承主成分分析网络(PCANet) 数据增强 L2,1范数故障诊断

Facilitating spectral analyses,simplification,and new tools through deep neural networks

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Magnetic Resonance Letters 2022年第1期2卷 56-58,I0003页

作者： Fa-An chao yue zhang R.Andrew Byrd NCI RAS Initiative Cancer Research Technology ProgramFrederick National Laboratory for Cancer ResearchLeidos Biomedical ResearchFrederickMD21701-4907United States Center for Structural Biology Center for Cancer ResearchNational Cancer InstituteFrederickMD21702-1201United States

In a recent publication it was shown that homonuclear scalar couplings in directly detected protein NMR spectra can be“decoupled”using deep neural networks,including cases where existing methods fail[1].The work harkens back to the introduction of maximum entropy and non-uniform sampling,and it elegantly illustrates how new approaches can be devised in the conceptualization of NMR experiments,freeing researchers from conventional thinking and *** work opens up a new era in biomolecular NMR spectroscopy,where experimental design is tailored towards processing with deep neural networks.(https://***/10.1021/jacs.1c04010).

关键词： entropy illustrate scalar

Controlling Morphology of Active Layer by Tuning Coplanarity of the Centrality in Acceptor-Donor-Acceptor Small Molecules for Photovoltaic Application

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Chinese Journal of Chemistry 2013年第11期31卷 1439-1448页

作者： Pan zhang chao Li yue Zhao Yaowen Li Yingfeng Tu Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application Department of Polymer Science and Engineering College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou Jiangsu 215123 China

A series of acceptor-donor-acceptor alternative small molecules were synthesized containing electron-donating central building moieties of phenothiazine, 2,7-carbazole and thieno[3,4-b]thiophene and electron-accepting moie- ties of tetrazine on both sides. The various conformations of the central blocks, with the coplanarity in an order of phenothiazine〈2,7-carbazole〈thieno[3,4-b]thiophene, have an obvious influence on the optical, electrochemical property and the crystallinity of small molecule. In addition, the blend films between small molecule and （6,6）-phenyl-C6rbutyric acid methyl ester offered significantly various morphologies, changing from uniform sur- face to interpenetrated networks. As a result, the bulk heterojunction photovoltaic devices based on the three small molecules provided varied performance, and the highest coplanar molecule based device exhibited the best photo- voltaic performance.

关键词： acceptor-donor-acceptor small molecules central blocks coplanarity morphology

A systematic evaluation of computational methods for predicting translated non-canonical ORFs from ribosome profiling data

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Journal of Genetics and Genomics 2024年第1期51卷 105-108页

作者： Tianyu Lei yue Chang chao Yao Hong zhang College of Ecology Lanzhou UniversityLanzhouGansu 730000China Cuiying Honors College Lanzhou UniversityLanzhouGansu 730000China

Ribosome profiling(Ribo-Seg)enables genome-wide survey of translational activities at nucleotide resolution by enriching and sequencing ribosome-protected fragments(RPFs)in the cell(Ingolia et al.,2009).Based on the characteristic distribution of RPFs in Ribo-Seq,such as enrichment in open reading frames(ORFs)and three-nucleotide periodicity,many computational methods have been developed to detect translated ORFs from Ribo-Seq data(Wang et al.,2020a).

关键词： translated enable canonical

Performance improvement of β-Ga2O3 SBD-based rectifier with embedded microchannels in ceramic substrate

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Science China(Information Sciences) 2024年第5期67卷 341-342页

作者： Wen HONG chao zhang Fang zhang Xuefeng ZHENG Xiaohua MA yue HAO State Key Laboratory of Wide-Bandgap Semiconductor Devices and Integrated Technology School of MicroelectronicsXidian University

With the development of integrated circuits, there is a growing demand for higher power devices [1]. Gallium oxide（Ga2O3） holds promise for high power devices due to its wide bandgap and high breakdown electric field strength [2].However, its low thermal conductivity induces severe selfheating effects, limiting its performance and ***, effective thermal management techniques are urgently needed for Ga2O3devices.

关键词： Gallium compounds

A special o-dialdehyde fluorescent probe simultaneously sensing Hcy,GSH and its application in living cells and zebrafish imaging

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Chinese Chemical Letters 2021年第9期32卷 2873-2876页

作者： Yongbin zhang Yu zhang Yongkang yue Jianbin chao Fangjun Huo Caixia Yin Shanxi Key Laboratory of Functional Molecules Research Institute of Applied ChemistryShanxi UniversityTaiyuan 030006China School of Chemistry and Chemical Engineering Shanxi UniversityTaiyuan 030006China Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education Institute of Molecular ScienceShanxi UniversityTaiyuan 030006China Scientific Instrument Center Shanxi UniversityTaiyuan 030006China

The development of fluorescent probes enabling to distinguish Cys,Hcy and GSH has always been a considerable challenge,in particular the distinction of Hcy and other two biothiols,because Hcy has a very similar structure with Cys and a relatively lower concentration in living *** this work,a special o-dialdehyde fluorescent probe,quinoline-2,3-dicarboxaldehyde(QDA),has been synthesized and demonstrated superior performance in differentiating detection of Hcy and GSH,which is different from the previous reported o-dialdehyde probes specifically detecting ***,the probe can selectively distinguish Hcy and GSH from different signal channels in living cells and zebrafish,meaning it has great potential in biological *** finding will provide a novel idea for the design of fluorescent probes to distinguish biothiols.

关键词： o-Dialdehyde Distinguish Hcy GSH Bioimaging