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International English Education Research 2014年第10期 94-96页

作者： chao-wang yongchun-xie xingqiang-tan Panzhihua University Panzhihua Sichuan 617000

As the application undergraduate course colleges and universities, a distinctive talent training system must be formed to achieve the target of practical and innovative talents training, which needs to constantly explore and innovate teaching mode. In the paper, talent training model based on the occupation ability development and Excellence Engineer training has carried on the deep discussion and research, thorough study and research.

关键词： management of teaching development of occupation ability excellence engineer training personnel training mode

Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer's disease

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Neural Regeneration Research 2025年第3期20卷 613-631页

作者： Yanxin Shen Guimei Zhang Chunxiao Wei Panpan Zhao yongchun wang Mingxi Li Li Sun Department of Neurology and Neuroscience Center The First Hospital of Jilin UniversityJilin UniversityChangchunJilin ProvinceChina Cognitive Impairment Center Department of NeurologyThe First Hospital of Jilin UniversityJilin UniversityChangchunJilin ProvinceChina

Alzheimer's disease is an age-related neurodegenerative disorder with a complex and incompletely understood pathogenesis. Despite extensive research, a cure for Alzheimer's disease has not yet been found. Oxidative stress mediates excessive oxidative responses, and its involvement in Alzheimer's disease pathogenesis as a primary or secondary pathological event is widely accepted. As a member of the selenium-containing antioxidant enzyme family, glutathione peroxidase 4 reduces esterified phospholipid hydroperoxides to maintain cellular redox homeostasis. With the discovery of ferroptosis, the central role of glutathione peroxidase 4 in anti-lipid peroxidation in several diseases, including Alzheimer's disease, has received widespread attention. Increasing evidence suggests that glutathione peroxidase 4 expression is inhibited in the Alzheimer's disease brain, resulting in oxidative stress, inflammation, ferroptosis, and apoptosis, which are closely associated with pathological damage in Alzheimer's disease. Several therapeutic approaches, such as small molecule drugs, natural plant products, and non-pharmacological treatments, ameliorate pathological damage and cognitive function in Alzheimer's disease by promoting glutathione peroxidase 4 expression and enhancing glutathione peroxidase 4 activity. Therefore, glutathione peroxidase 4 upregulation may be a promising strategy for the treatment of Alzheimer's disease. This review provides an overview of the gene structure, biological functions, and regulatory mechanisms of glutathione peroxidase 4, a discussion on the important role of glutathione peroxidase 4 in pathological events closely related to Alzheimer's disease, and a summary of the advances in small-molecule drugs, natural plant products, and non-pharmacological therapies targeting glutathione peroxidase 4 for the treatment of Alzheimer's disease. Most prior studies on this subject used animal models, and relevant clinical studies are lacking. Future clinica

关键词： apoptosis ferroptosis inflammation lipid peroxidation natural plant products neurodegenerative disorder neuroprotection oxidative stress small-molecule drugs

Control capability analysis for complex spacecraft thruster configurations

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Science China(Technological Sciences) 2010年第8期53卷 2089-2096页

作者： wang Min xie yongchun Beijing Institute of Control Engineering Beijing 100190China National Key Laboratory of Science and Technology on Space Intelligent Control Beijing 100190China

The set of forces and moments that can be generated by thrusters of a spacecraft is called the"control capability"with respect to the thruster *** the control capability of a thruster configuration is adequate to fulfill a given space mission,we say this configuration is a feasible one with respect to the *** study proposed a new way to analyze the control capability of the complex thruster *** mathematical definitions of feasibility were proposed,based on which a criterion to judge the feasibility of the thruster configuration was presented through calculating the shortest distance to the boundary of the controllable region as a function of the thruster ***,control capability analysis for the complex thruster configuration based on its feasibility with respect to the space mission was given followed by a 2-D thruster configuration example to demonstrate its validity.

关键词： thruster configuration control capability

Optimal impulsive ellipse-to-circle coplanar rendezvous

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Science China(Technological Sciences) 2009年第5期52卷 1435-1445页

作者： CHEN ChangQing xie yongchun Beijing Institute of Control Engineering National Laboratory of Space Intelligent ControlBeijing 100190China

The problem of ellipse-to-circle coplanar rendezvous with chaser spacecraft in low eccentricity was investigated in this *** reference frame established in the centroid of the target spacecraft,the process of ellipse-to-circle coplanar rendezvous was described by the relative equations based on cy-lindrical reference frame,and then the solutions and distributions of optimal rendezvous models of a kind of close ellipse-to-circle coplanar rendezvous were *** simulation results showed that the guidance law based on the optimal rendezvous model in this research has good performance,and that the distributions of optimal rendezvous models of ellipse-to-circle coplanar rendezvous with the chaser spacecraft in low eccentricity are similar,albeit with slight difference,to those of rendezvous between close circular *** work in this paper is a useful extension to Prussing's optimal ren-dezvous theory between close circular orbits.

关键词： ellipse-to-circle rendezvous optimal impulsive rendezvous rendezvous model

Knowledge Graph-Based Image Recognition Transfer Learning Method for On-Orbit Service Manipulation

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Space(Science & Technology) 2021年第1期2021卷 164-172页

作者： Ao Chen yongchun xie Yong wang Linfeng Li Beijing Institute of Control Engineering BeijingChina Science and Technology on Space Intelligent Control Laboratory BeijingChina

Visual perception provides state information of current manipulation scene for control system,which plays an important role in on-orbit service *** the development of deep learning,deep convolutional neural networks(CNNs)have achieved many successful applications in the field of visual *** CNNs are only effective for the application condition containing a large number of training data with the same distribution as the test data;however,real space images are difficult to obtain during large-scale ***,deep CNNs can not be directly adopted for image recognition in the task of on-orbit service *** order to solve the problem of few-shot learning mentioned above,this paper proposes a knowledge graph-based image recognition transfer learning method(KGTL),which learns from training dataset containing dense source domain data and sparse target domain data,and can be transferred to the test dataset containing large number of data collected from target *** average recognition precision of the proposed method is 80.5%,and the average recall is 83.5%,which is higher than that of ResNet50-FC;the average precision is 60.2%,and the average recall is 67.5%.The proposed method significantly improves the training efficiency of the network and the generalization performance of the model.

关键词： Service Visual manipulation

A High Performance Cobalt-Doped ZnO Visible Light Photocatalyst and Its Photogenerated Charge Transfer Properties

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Nano Research 2011年第11期4卷 1144-1152页

作者： yongchun Lu Yanhong Lin Dejun wang Lingling wang Tengfeng xie Tengfoi Jiang State Key Laboratory of Theoretical and Cornputational Chemistry State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University Cheangchun 130012 China.

Highly photocatalytically active cobalt-doped ZnO （ZnO：Co） nanorods have been prepared by a facile hydrothermal process. X-ray diffraction, X-ray photoelectron spectroscopy, Raman scattering and UV-vis diffuse reflectance spectroscopy confirmed that the dopant ions substitute for some of the lattice zinc ions, and furthermore, that Co〉 and Co〉 ions coexist. The as-prepared ZnO：Co samples have an extended light absorption range compared with pure ZnO and showed highly efficient photocatalytic activity, only requiring 60 rain to decompose -93% of alizarin red dye under visible light irradiation （λ 〉 420 nm）, The photophysical mechanism of the visible photocatalytic activity was investigated with the help of surface photovoltage spectroscopy. The results indicated that a strong electronic interaction between the Co and ZnO was present, and that the incorporation of Co promoted the charge separation and enhanced the charge transfer ability and, at the same time, effectively inhibited the recombination of photogenerated charge carriers in ZnO, resulting in high visible light photocatalytic activity.

关键词： ZnO:Co visible light irradiation surface photovoltage photocatalysis

Effects of ultrasonic treatment on dithiothreitol(DTT) assay measurements for carbon materials

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Journal of Environmental Sciences 2019年第10期31卷 51-58页

作者： Haotian Jiang Yun xie Yanli Ge Hong He yongchun Liu State Key Joint Laboratory of Environment Simulation and Pollution Control Research Center forEco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China Aerosol and Haze Laboratory Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 China University of Chinese Academy of Sciences Beijing 100049 China Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China Center for Excellence in Urban Atmospheric Environment Institute of Urban Environment Chinese Academy of Sciences Xiamen 361021China

The dithiothreitol(DTT)assay is the most commonly used method to quantify the oxidative potential of fine ***,the reported DTT decay rates of carbon black(CB)materials vary greatly among different *** might have resulted from either the intrinsic toxicity of CB or the unsuitability of the DTT assay protocol for CB *** the current study,the protocol of the DTT assay for CB materials has been carefully *** was found that the dispersion degree of CB particles in water has a great influence on the DTT decay rate of CB *** CB particles(special black 4A(SB4A)and Printex U)and single-walled carbon nanotube tube(SWCNT),the DTT decay rate after sonication for 10 min became 4.2,4.6 and 1.7 times higher than that without *** rate continued to grow as a function of ultrasound time up to 30 min of *** the concentration of soluble transition metals and surface oxygen-containing species such as carbonyls increased slightly with sonication,they had no significant effects on the measured DTT activity,while the increase in the dispersion degree of aggregates was found to play a vital role in the observed enhancement of the DTT decay rates for different CB *** on our results,30 min of sonication is recommended for sample dispersion when measuring the DTT decay rate of CB materials.

关键词： Sonication Dispersion Dithiothreitol(DTT) assay Carbon nanomaterials

On the Robust Outer Loop Control of Robotic Systems 36

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On the Robust Outer Loop Control of Robotic Systems

Relative State Estimation of Model-Unknown Spinning Noncooperative Target Using Stereo EKF-SLAM 36

第36届中国控制会议

作者： Hanlei wang Tiantian Jiang Shuanfeng Xu yongchun xie Science and Technology on Space Intelligent Control Laboratory Beijing Institute of Control Engineering

ISBN: (纸本)9781538629185

Most industrial/commercial robots typically employ an unmodifiable inner joint controller and only the joint position or velocity command can be designed by the user. In this paper, we propose a robust approach to the control of such robotic systems with the uncertainty and nonlinearity being taken into consideration. We develop robust outer loop controllers that can rigorously ensure the uniform ultimate boundedness of the closed-loop system, without relying on the ad hoc assumption of the conventional kinematic controller that the effects of the dynamics can be neglected. The performance of the proposed robust outer loop controllers is shown by numerical simulations with a three-DOF（degree-of-freedom） manipulator.

关键词： Inner/outer loop outer loop control robust control robotics

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Relative State Estimation of Model-Unknown Spinning Noncoope...

第36届中国控制会议

作者： Yipeng Li yongchun xie Beijing Institute of Control Engineering Science and Technology on Space Intelligent Control Laboratory

ISBN: (纸本)9781538629185

A new method for real-time relative state estimation of noncooperative target using stereo vision is *** mainly deals with spinning target without any prior information known and can be applied in many space missions,such as on-orbit servicing,space debris mitigation,*** method is inspired by the popular SLAM algorithm in computer vision community which is used for locate a robot in unknown *** EKF（extended Kalman filter） based method is chosen for relative state and model parameter estimation and map building due to the limited onboard computing *** algorithm consists of three parts:（1） geometric reference frame selection,which formulate the direct measurement for stereo vision;（2）localization and mapping,which reconstruct the features on target’s surface and track pose between serial frames;（3） model parameter estimation,which estimate the inertial axes and center-of-mass（CM） of *** from numerical simulation demonstrate the performance and viability of the proposed algorithm.

关键词： Noncooperative target EKF-SLAM Model Unknown Stereo vision

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节能燃气加热器中折流板的应力分析与优化

江苏大学学报（自然科学版） 2025年第1期46卷 43-49页

作者：杜敏张帅平张永春王跃成张嘉迪江苏大学能源与动力工程学院江苏镇江212013 江苏省特种设备安全监督检验研究院江苏南京210036

为了研究加热器中暴露在高温环境下折流板的应力分布规律与安全可靠性,基于有限元分析方法对其进行应力分析,选取危险截面路径进行应力线性化分析,并根据安全评定结果对折流板结构进行优化.结果表明:尖角造成的应力集中对折流板的应力... 详细信息

为了研究加热器中暴露在高温环境下折流板的应力分布规律与安全可靠性,基于有限元分析方法对其进行应力分析,选取危险截面路径进行应力线性化分析,并根据安全评定结果对折流板结构进行优化.结果表明:尖角造成的应力集中对折流板的应力分布影响较大,其薄膜应力P L过高是导致应力评定危险的主要原因;折流板整体应力大小随着燃料进口速度的增大而增高,温度与热应力大小呈正相关,在不同速度下应力变化趋势相似,换热管束与折流板连接处的结构不连续会造成应力升高;优化方案中,当钝化尖角后,折流板最大热应力降低16.7%,再覆盖热障涂层时的最大热应力较钝化尖角时降低44.5%,较原始结构降低53.7%,且整体热应力下降,优化后折流板强度评定为合格.

关键词：折流板温度场热流固耦合热应力应力评定热障涂层