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Ground states, solitons and spin textures in spin-1 Bose-Einstein condensates

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Frontiers of physics 2013年第3期8卷 302-318页

作者： Shu-Wei Song Lin Wen chao-fei liu S.-C. Gou Wu-Ming liu Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 China School of Science Jiangxi University of Science and Technology Ganzhou 341000 China Department of Physics National Changhua University of Education Changhua 50058 Taiwan China

We present an overview of our recent theoretical studies on the quantum phenomena of the spin-1 Bose Einstein condensates, including the phase diagram, soliton solutions and the formation of the topological spin textures. A brief exploration of the effects of spin-orbit coupling on the ground-state properties is given. We put forward proposals by using the transmission spectra of an optical cavity to probe the quantum ground states： the ferromagnetic and polar phases. Quasi-one-dimension solitons and ring dark solitons are studied. It is predicted that characteristics of the magnetic solitons in optical lattice can be tuned by controlling the long-range light-induced and static magnetic dipole- dipole interactions; solutions of single-component magnetic and single-, two-, three-components polar solitons are found; ring dark solitons in spin-1 condensates are predicted to live longer lifetimes than that in their scalar counterparts. In the formation of spin textures, we have considered the theoretical model of a rapidly quenched and fast rotating trapped spin-1 Bose Einstein condensate, whose dynamics can be studied by solving the stochastic projected Gross-Pitaevskii equations. Spontaneous generation of nontrivial topological defects, such as the hexagonal lattice skyrmions and square lattice of half-quantized vortices was predicted. In particular, crystallization of merons （half skyrmions） can be generated in the presence of spin-orbit coupling.

关键词： Bose-Einstein condensate spinor vortex lattice soliton spin orbit coupling

Spin-orbit coupling adjusting topological superfluid of mass-imbalanced Fermi gas

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Chinese Physics B 2022年第9期31卷 208-216页

作者： Jian Feng Wei-Wei Zhang Liang-Wei Lin Qi-Peng Cai Yi-Cai Zhang Sheng-Can Ma chao-fei liu School of Science Jiangxi University of Science and TechnologyGanzhou 341000China School of Physics and Electronic Engineering Guangzhou UniversityGuangzhou 510006China

Topological superfluid state is different from the normal superfluid one due to the excitation energy gap on the *** to obtain the topological superfluid state by using spin-orbit coupling to control the s-waves paired mass-imbalanced Fermi gas is a recent novel *** this paper,we study the topological superfluid phase diagram of two-dimensional mass-imbalanced Fermi gas with Rashba spin-orbit coupling at zero *** find that due to the competition among mass imbalance,pairing interaction and spin-orbit coupling,there is a double-well structure in the thermodynamic potential,which affects the properties of the ground state of the *** comprehensively give the phase diagrams of the system on the plane of spin-orbit coupling and chemical potential,and the phase diagrams on the plane of the reduced mass ratio and two-body binding *** study not only points out the stable region of topolog-ical superfluid state of mass-imbalanced Fermi gas,but also provides a detailed theoretical basis for better observation of topological superfluid state in experiments.

关键词： topological superfluid mass-imbalanced spin-orbit coupling Fermi gas

First-principles study on stability and superconductivity of ternary hydride LaYH_(x)(x=2,3,6 and 8)

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Chinese Physics B 2024年第8期33卷 415-420页

作者：颜小珍周幸姿刘超飞徐寅力黄毅斌盛晓伟陈杨梅 School of Science Jiangxi University of Science and TechnologyGanzhou 341000China Department of Physics Anhui Normal UniversityWuhu 241000China Anhui Province Key Laboratory of Optoelectric Materials Science and Technology Wuhu 241000China

Recent studies have shown that the La-and Y-hydrides can exhibit significant superconducting properties under high *** this paper,we investigate the stability,electronic and superconducting properties of LaYH_(x)(x=2,3,6 and 8)under 0-200 *** is found that LaYH_(2) stabilizes in the C2/m phase at ambient pressure,and transforms to the Pmmn phase at 67 ***_(3) stabilizes in the C2/m phase at ambient pressure,and undergoes phase transitions of C2/m→P2_(1)/m→R3m at 12 GPa and 87 GPa,***_(6) stabilizes in the P4_32_12 phase at ambient pressure,and undergoes phase transitions of P4_(3)2_(1)2→P4/mmm→Cmcm at 28 GPa and 79 GPa,***_(8) stabilizes in the Imma phase at 60 GPa and transforms to the P4/mmm phase at 117 *** of the electronic band structures show that the P4/mmm-LaYH_(8) and all phases of LaYH_(2) and LaYH_(3) exhibit metallic *** the metallic phases,we then study their superconducting *** calculated superconducting transition temperatures(T_c)are 0.47 K for C2/m-LaYH_(2) at 0 GPa,0 K for C2/m-LaYH_(3) at 0 GPa,and 55.51 K for P4/mmm-LaYH_(8) at 50 GPa.

关键词： superconductivity high pressure first-principles study phase transitions

Clinical effects of phospholipase D2 in attenuating acute pancreatitis

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World Journal of Gastroenterology 2025年第2期31卷 52-60页

作者： Jin-Wei Niu Guo-chao Zhang Wu Ning Hai-Bin liu Hua Yang chao-Feng Li Department of General Surgery China-Japan Friendship HospitalBeijing 100029China

BACKGROUND The objective of the current study was to elucidate the clinical mechanism through which phospholipase D2(PLD2)exerted a regulatory effect on neutrophil migra-tion,thereby alleviating the progression of acute *** To elucidate the clinical mechanism through which PLD2 exerted a regulatory effect on neutrophil migration,thereby alleviating the progression of acute *** The study involved 90 patients diagnosed with acute pancreatitis,admitted to our hospital between March 2020 and November 2022.A retrospective analysis was conducted,categorizing patients based on Ranson score severity into mild(n=25),moderate(n=30),and severe(n=35)*** data was collected for each *** blot analysis assessed PLD2 protein expression in patient ***-time reverse transcription polymerase chain reaction was used to evaluate the mRNA expression of chemokine receptors associated with neutrophil *** levels of inflammatory factors in patients were detected using enzyme-linked immunosorbent *** migration tests were conducted to compare migration of neutrophils across groups and analyze the influence of PLD2 on neutrophil *** Overall data analysis did not find significant differences between patient groups(P>0.05).The expression of PLD2 protein in the severe group was lower than that in the moderate and mild groups(P<0.05).The expression level of PLD2 in the moderate group was also lower than that in the mild group(P<0.05).The severity of acute pancreatitis is negatively correlated with PLD2 expression(r=-0.75,P=0.002).The mRNA levels of C-X-C chemokine receptor type 1,C-X-C chemokine receptor type 2,C-C chemokine receptor type 2,and C-C chemokine receptor type 5 in the severe group are significantly higher than those in the moderate and mild groups(P<0.05),and the expression levels in the moderate group are also higher than those in the mild group(P<0.05).The levels of C-reactive protein,tumo

关键词： Phospholipase D2 Neutrophil migration Acute pancreatitis Retrospective analysis Inflammatory response

Transarterial chemoembolization combined with lenvatinib and sintilimab vs lenvatinib alone in intermediate-advanced hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 52-61页

作者： fei-Da Wu Hai-Feng Zhou Wei Yang Di Zhu Bi-fei Wu Hai-Bin Shi Sheng liu Wei-Zhong Zhou Department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)is the most common form of liver cancer that has limited treatment options and a poor *** chemoembolization(TACE)is the first-line treatment for intermediate-stage HCC but can induce tumour hypoxia,thereby promoting *** studies suggested that combining TACE with anti-angiogenic therapies and immunotherapy might im-prove ***,a tyrosine kinase inhibitor,has demonstrated superior outcomes compared to sorafenib,while immune checkpoint inhibitors such as sintilimab show potential when combined with ***,the efficacy and safety of TACE combined with lenvatinib and sintilimab(TACE+SL)compared to TACE with lenvatinib alone(TACE+L)in patients with intermediate-ad-vanced HCC has not yet been *** To evaluate the efficacy and safety of TACE+SL therapy in comparison to TACE+L therapy in patients with intermediate-advanced *** A retrospective analysis was performed on patients with intermediate-advanced HCC who received TACE plus lenvatinib with or without sintilimab between September 2019 and September *** characteristics were compared,and propensity score matching was *** survival(OS),progression-free survival(PFS),and objective response rate(ORR)were evaluated between the two groups,and adverse events were *** The study included 57 patients,with 30 in the TACE+SL group and 27 in the TACE+L *** TACE+SL group demonstrated significantly improved median PFS and OS compared to the TACE+L group(PFS:14.1 months vs 9.6 months,P=0.016;OS:22.4 months vs 14.1 months,P=0.039),along with a higher ORR(70.0%vs 55.6%).After propensity score matching,30 patients were included,with the TACE+SL group again showing longer median PFS and a trend toward improved OS(PFS:14.6 months vs 9.2 months,P=0.012;OS:23.9 months vs 16.3 months,P=0.063),and a higher ORR(73.3%vs 53.3%).No severe adverse events were *** TACE+SL demonstrat

关键词： Hepatocellular carcinoma Transarterial chemoembolization Sintilimab Lenvatinib Immunotherapy Programmed cell death 1 Prognosis

Different effects of orexin-A on AMPA receptor-mediated currents of on- and off-type ganglion cells in rat retina

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Different effects of orexin-A on AMPA receptor-mediated curr...

Engineered Cancer Nanovaccines:A New Frontier in Cancer Therapy

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： chao ZHENG,fei liu,Xiong-Li YANG~*,Yong-Mei ZHONG~* Institute of Neurobiology,Institutes of Brain Science and State Key Laboratory of Medical Neurobiology,Fudan University,Shanghai 200032,China

Objective Two novel neuropeptides,orexin-A and orexin-B,are identified as endogenous ligands of two orphan G-protein-coupled receptors:orexin 1 and orexin 2 receptors(OXR and OXR).This neuropeptide system is involved in a variety of physiological processes,such as sleep/wake regulation,feeding behaviors *** most of the mammalian suprachiasmatic nucleus(SCN) circadian clock is photoentrained by photic signals from the retina through the retinohypothalamic tract,little is known about the distribution and function of orexins in *** purpose of this study is to investigate how orexins and OXRs are expressed in the rat retina and how orexin-A modulates AMPA receptors in retinal ganglion cells(GCs).Methods Western blot analysis and immunocytochemistry were used to explore the distribution of orexins and OXRs in rat *** of orexin-A on AMPA receptor-mediated currents were investigated in freshly dissociated GCs by whole cell patchclamp recording *** By immunocytochemistry,we show that orexin-A and orexin-B are strongly expressed in horizontal,bipolar,amacrine cells(ACs) and ***,OXR immunoreactivity is observed in most of GCs and all dopaminergic ACs,as well as in both outer and inner plexiform *** contrast,no obvious OXR immunostaining is detectable in the rat *** patch-clamp whole-cell recording,we first characterized AMPA receptor-mediated currents of ***,we found that 100 nM orexin-A suppressed AMPA-induced currents in 53 out of 59 OFF-type GCs *** average,following the perfusion of 100 nM orexin-A,the AMPAinduced currents were reduced to 62.0±2.1%of control(P < 0.0001).In contrast,100 nM orexin-A increased AMPAinduced currents in 11 out of 14 ON-type GCs to 153.7±8.5%of control(P < 0.0001).The effects of orexin-A were completely blocked by TCS1102,an antagonist for both OXR and OXR(n = 7).In most of ON- and OFF-GCs,the effects of orexin-A were eliminated by SB334867,a selective OXR antagoni

关键词： orexin-A orexin 1 receptor AMPA receptor neurotransmission retina ganglion cells

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Nano-Micro Letters 2025年第2期17卷 134-168页

作者： Yijie Wang Congrui liu chao Fang Qiuxia Peng Wen Qin Xuebing Yan Kun Zhang Central Laboratory and Department of Medical Ultrasound Sichuan Academy of Medical SciencesSichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaNo.32West Second SectionFirst Ring RoadChengdu 610072People’s Republic of China Department of Stomatology and Central Laboratory School of MedicineShanghai Tenth People’s HospitalTongji UniversityNO.301 Yan‑Chang‑Zhong RoadShanghai 200072People’s Republic of China Jiangsu Provincial Innovation and Practice Base for Postdoctors Suining People’s HospitalAffiliated Hospital of Xuzhou Medical UniversityNo.2Bayi West RoadSuiningXu Zhou 221000Jiangsu ProvincePeople’s Republic of China

Vaccinations are essential for preventing and treating disease,especially cancer nanovaccines,which have gained considerable interest recently for their strong anti-tumor immune *** can prompt the immune system to generate antibodies and activate various immune cells,leading to a response against tumor tissues and reducing the negative effects and recurrence risks of traditional chemotherapy and *** enhance the flexibility and targeting of vaccines,nanovaccines utilize nanotechnology to encapsulate or carry antigens at the nanoscale level,enabling more controlled and precise drug delivery to enhance immune *** nanovaccines function by encapsulating tumor-specific antigens or tumor-associated antigens within *** small size of these nanomaterials allows for precise targeting of T cells,dendritic cells,or cancer cells,thereby eliciting a more potent anti-tumor *** this paper,we focus on the classification of carriers for cancer nanovaccines,the roles of different target cells,and clinically tested cancer nanovaccines,discussing strategies for effectively inducing cytotoxic T lymphocytes responses and optimizing antigen presentation,while also looking ahead to the translational challenges of moving from animal experiments to clinical trials.

关键词： Cancer nanovaccines Immunotherapy Nanobiotechnology Immune targets Signaling pathway

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang Li Xiaomei Tang Jinyu Zeng Yige Song chao Xu Kai Zhao Guoqiang liu Youming Lu Xinyan Li Kai Shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

Flexible Graphene Field‑Effect Transistors and Their Application in Flexible Biomedical Sensing

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Nano-Micro Letters 2025年第2期17卷 252-313页

作者： Mingyuan Sun Shuai Wang Yanbo Liang chao Wang Yunhong Zhang Hong liu Yu Zhang Lin Han Institute of Marine Science and Technology Shandong UniversityQingdao 266237ShandongPeople’s Republic of China State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100ShandongPeople’s Republic of China School of Integrated Circuits Shandong UniversityJinan 250100ShandongPeople’s Republic of China Shandong Engineering Research Center of Biomarker and Artificial Intelligence Application Jinan250100ShandongPeople’s Republic of China

Flexible electronics are transforming our lives by making daily activities more *** to this innovation are field-effect transistors(FETs),valued for their efficient signal processing,nanoscale fabrication,low-power consumption,fast response times,and ***,known for its exceptional mechanical properties,high electron mobility,and biocompatibility,is an ideal material for FET channels and *** combination of graphene and FETs has given rise to flexible graphene field-effect transistors(FGFETs),driving significant advances in flexible electronics and sparked a strong interest in flexible biomedical ***,we first provide a brief overview of the basic structure,operating mechanism,and evaluation parameters of FGFETs,and delve into their material selection and patterning *** ability of FGFETs to sense strains and biomolecular charges opens up diverse application *** specifically analyze the latest strategies for integrating FGFETs into wearable and implantable flexible biomedical sensors,focusing on the key aspects of constructing high-quality flexible biomedical ***,we discuss the current challenges and prospects of FGFETs and their applications in biomedical *** review will provide valuable insights and inspiration for ongoing research to improve the quality of FGFETs and broaden their application prospects in flexible biomedical sensing.

关键词： Flexible Graphene Field-effect transistor Wearable Implantable Biosensor