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呼吸重症监护室肺部多重耐药菌的危险因素

武汉大学学报（医学版） 2024年第1期45卷 99-103页

作者：木尼热·艾尼瓦尔倪岚程真顺吴长蓉南京医科大学附属克州人民医院新疆阿图什845350 武汉大学中南医院呼吸与危重症医学科湖北武汉430071

目的:回顾性研究呼吸重症监护室(RICU)住院患者肺部多重耐药菌(MDRO)感染的临床特点,进一步探讨RICU患者肺部多重耐药菌感染的危险因素。方法:选取2021年1月至2021年12月在武汉大学中南医院RICU收治的502例患者为研究对象,收集患者临床... 详细信息

目的:回顾性研究呼吸重症监护室(RICU)住院患者肺部多重耐药菌(MDRO)感染的临床特点,进一步探讨RICU患者肺部多重耐药菌感染的危险因素。方法:选取2021年1月至2021年12月在武汉大学中南医院RICU收治的502例患者为研究对象,收集患者临床资料,根据药敏试验结果分为多重耐药菌组(n=166)与非多重耐药菌组(n=336),采用SPSS 25.0系统分别行单因素和多因素分析RICU患者肺部多重耐药菌感染的危险因素。结果:502例患者中MDRO感染者166例。单因素分析显示,两组患者RICU住院时间>14 d、气切或气管插管、有创机械通气、中心静脉导管、使用3种及以上抗生素、多器官功能衰竭的差异均有统计学意义(P14 d及多器官功能衰竭是肺部MDRO感染的危险因素(P<0.05)。结论:RICU患者肺部多重耐药菌感染率很高,抗生素的合理使用、尽量减少有创操作及缩短RICU住院时间可能有利于减少多重耐药菌感染的发生率。

关键词：呼吸重症监护室多重耐药菌危险因素

塔里木盆地库车坳陷克拉苏构造带西部盐相关构造变形

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天然气地球科学 2024年第6期35卷 988-999页

作者：刘恣君范坤宇涂国煜吴昌荣郭虹兵钟川楠苗如霖邓宾成都理工大学能源学院四川成都610059 成都理工大学“油气藏地质及开发工程全国重点实验室” 四川成都610059 中国石油塔里木油田公司勘探开发研究院新疆库尔勒841000

库车前陆盆地克拉苏构造带为塔里木盆地油气勘探重点领域,其天然气资源量超万亿立方米,但长期受困于含盐褶皱冲断带构造变形复杂等问题,导致研究区构造圈闭落实难度大。基于三维地震资料精细解释,构建构造几何学地质模型,解析克拉苏构... 详细信息

库车前陆盆地克拉苏构造带为塔里木盆地油气勘探重点领域,其天然气资源量超万亿立方米,但长期受困于含盐褶皱冲断带构造变形复杂等问题,导致研究区构造圈闭落实难度大。基于三维地震资料精细解释,构建构造几何学地质模型,解析克拉苏构造带横向盐相关构造样式以及构造组合特征。研究结果表明,克拉苏构造带西部分别发育阿瓦特段盐上单斜—高幅度厚盐枕—盐下高幅叠瓦+堆垛构造,博孜段盐上单斜—盐焊接+低幅盐枕—盐下低幅叠瓦+冲起构造,大北段盐上单斜+逆冲断裂—盐焊接+盐背斜—盐下低幅叠瓦+堆垛背斜构造,表现出横向上“东西分段”,纵向上“差异叠置”构造特征。结合膏岩岩层横向差异展布特征和主干断裂叠置关系,揭示阿瓦特、博孜和大北段走向构造分段差异主要取决于先存构造和盐岩厚度的不均匀性。

关键词：克拉苏构造带盐相关构造三维构造建模先存构造盐岩厚度

Relationship between Tanlu Fault and Hydrocarbon Accumulation in Liaozhong Sag, Bohai Bay, Eastern China

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Journal of Earth Science 2014年第2期25卷 324-336页

作者： Guosheng Xu Zhixing Xu Deyu Gong Donghong Zhou changrong wu Xiaoping Luo Jianping Li State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of Technology Research Institute of Petroleum Exploration and Development PetroChina Exploration and Development Research Institute of Tianjin Branch CNOOC

Tanlu fault （Liaozhong segment） goes straight through Liaodong Bay along NNE direc- tion and it is divided into three segments, i.e., the northern segment, the middle segment and the south- ern segment, according to the differences in structural features. There are obvious changes in deposit thickness, sag structure, tectonic nature and other aspects of the layers. Tanlu fault is a special control- ling factor concerning the reservoir formation in Liaozhong sag. First, its activities affect paleogeo- morphology and paleogeographic framework and control the distribution of the sedimentary facies and then they proceed to control the distribution of the source rock and reservoir sand bodies. Second, its activities affect the formation and deformation of the structure, control the formation of abundant traps and cause the destruction of some traps. Third, its activities also affect the juxtaposition relation among the fault, the sand bodies and unconformity surfaces and control the function and efficacy of the three as the main hydrocarbon translocation system. In this paper the hydrocarbon reservoir formation process of JZ21-1, JXI-1 and LD27~2 oil and gas fields, the representatives of Tanlu strike slip fault zone are mainly analyzed. The modes of hydrocarbon reservoir formation can be generalized as follows--hydrocarbon source acts as ＂soil＂ and oil and gas as ＂nutrient＂; hydrocarbon expulsion relies on ＂roots＂; hydrocarbon migration relies on ＂trunks＂; reservoir forms in ＂brunches＂ and the whole process follows the pattern that ＂hydrocarbon accumulates in strike slips and oil and gas reservoir forms like the growth of trees＂.

关键词： Tanlu fault strike-slip fault Liaozhong sag formation of hydrocarbon.

Enhanced high-temperature mechanical properties of laser-arc hybrid additive manufacturing of Al-Zn-Mg-Cu alloy via microstructure control

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Journal of Materials Science & Technology 2024年第2期169卷 220-234页

作者： Dehua Liu Dongjiang wu Yunsong Wang Zhuo Chen changrong Ge Qingyu Zhao Fangyong Niu Guangyi Ma State Key Laboratory of High-performance Precision Manufacturing Dalian University of TechnologyDalian 116024China

Recently,rapid and cost-effective additive manufacturing solutions for lightweight aluminum alloys with excellent high-temperature mechanical properties have been increasingly in *** this study,we combined laser-arc hybrid additive manufacturing with solution and artificial aging treatments to achieve Al-Zn-Mg-Cu alloy with favorable high-temperature strength via microstructure *** pores became the major defect in the as-deposited and heat-treated *** continuous distribution of eutectics with hard-brittle characteristics at the grain boundaries was destructed following heat ***-densityηprecipitates were uniformly dispersed in the heat-treated Al-Zn-Mg-Cu alloy,whereas appeared coarsened and dissolved at 473 K,owing to the rapid diffusion of Zn and *** average 0.2%yield strength(318±16 MPa)and ultimate tensile strength(362±20 MPa)at 473 K af-ter heat treatment were enhanced by approximately 58%and 51%,respectively,compared to those of the as-deposited *** addition,theηprecipitates contributed to lattice distortions and strain fields,which prevented dislocation motion and increased slip deformation resistance at high *** as-deposited specimen exhibited intergranular fracture at 473 K,with cracks preferring to propagate along the aggregated ***,crack propagation proceeded in the sections with more pores in the heat-treated *** approach may provide a valid option for achieving alu-minum alloys with excellent high-temperature mechanical properties.

关键词： Laser-arc hybrid additive manufacturing Al-Zn-Mg-Cu alloy High-temperature strength Heat treatment,Microstructure evolution

Sedimentary filling characteristics and controlling factors of lacustrine microbial carbonates sequence in the Santos Basin,Brazil

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Petroleum Exploration and Development 2022年第4期49卷 785-796页

作者： HE Sai LI Guorong wu changrong LIU Shugen ZHANG Zhongmin SU Yushan ZHU Yixuan HE Zhao REN Jie WANG Yuchen ZHOU Wei WANG Yajie College of Energy Chengdu University of TechnologyChengdu 610059China State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of TechnologyChengdu 610059China Sichuan Zhongcheng Institute of Coalfield Geophysical Engineering Chengdu 610072China Sinopec Research Institute of Petroleum Exploration&Production Beijing 100083China

Based on comprehensive analysis of seismic,logging,core,thin section data,and stable isotopic compositions of carbon and oxygen,the sedimentary filling characteristics of the Lower Cretaceous Barra Velha Formation sequence in H oil field,Santos Basin,are studied,and the high-frequency sequence stratigraphic framework is established,and the spatial distribution of reef-shoal bodies are predicted and the controlling factors are *** the depositional period of the Barra Velha Formation,the study area is a slope-isolated platform-slope sedimentary pattern from southwest to northeast and the change of climate background from rift to depression periods has resulted in the variation of sedimentary characteristics from the lower third-order sequence SQ1(BVE 300 Member)of low-energy deep water to the upper third-order sequence SQ2(BVE 200 and 100 members)of high-energy shallow water in the Barra Velha *** activities of extensional faults and strike-slip faults in rift period and the sedimentary differentiation from platform margin to intra-platform in depression period made the sedimentary paleogeomorphology in these two periods show features of“three ridges and two depressions”.The reef-shoal bodies mainly developed in the SQ2-LHST period,with vertical development positions restricted by the periodic oscillation of the lake level,and developed on the top of each high-frequency sequence stratigraphic unit in SQ2-LHST in the *** strike-slip fault activity controlled the distribution of the reef-shoal bodies on the plane by changing the sedimentary *** positive flower-shaped strike-slip faults made the formation of local highlands at the margins of and inside the shallow water platforms and which became high-energy sedimentary zones,creating conditions for the development of reef-shoal bodies.

关键词： Santos Basin,Brazil Lower Cretaceous Barra Velha Formation lacustrine microbial carbonate high-frequency sequence sedimentary filling characteristics reef-shoal body development model

Features of the fault system and its relationship with migration and accumulation of hydrocarbon in Liaodong Bay

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Petroleum Science 2011年第3期8卷 251-263页

作者： Xu Guosheng Ma Ruolong Gong Deyu Zhou Donghong Li Jianping Guo Yonghua Yuan Haifeng wu changrong State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu University of Technology Chengdu Sichuan 610059 China Exploration and Development Research Institute Tianjin Branch of CNOOC （China） Co. Ltd. Tanggu Tianjin 300452 China

The fault system of Liaodong Bay developed extensively under the control of the Tanlu Fault. The fault system can be grouped into strike-slip faults of grade Ⅰ, trunk faults of grade Ⅱand branch faults （induced faults） of grade Ⅲ respectively based on its developmental scale. The faults of grade Ⅰ and Ⅱwere deep, early and large while the faults of grade Ⅲwere shallow, late and small. The formation, evolution and distribution features played a significant role in controlling the migration of oil and gas in both horizontal and vertical directions. The fluid transfer in the fault system occurred in the process of faulting. The strike-slip and trunk faults moved actively forming predominant pathways for oil and gas migration. The branch faults, with weak activity, generally controlled the development of traps and were beneficial for the accumulation and preservation of oil and gas. The faults of grade Ⅰ and Ⅱ formed the major migration pathways for oil and gas, but their fault activity rates appeared to vary along their strikes. The zones with a relatively low fault activity rate might be favorable for oil and gas accumulation. When the activities of strike-slip, trunk, and branch faults came to a halt, the fault seal behavior had a vitally important effect on the accumulation of oil and gas. The controlling role of the fault over fluid distribution was further analyzed by calculating the fault activity quantitatively.

关键词： Liaodong Bay fault system fault activity rate fault seal behavior migration andaccumulation of oil and gas

老年慢性阻塞性肺疾病患者营养风险与衰弱的横断面研究

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武汉大学学报（医学版） 2024年第9期45卷 1082-1087页

作者：刘灵芳方燕红董佳殷瑶郑星王睿珊龚相丹江红霞程真顺吴长蓉武汉大学中南医院呼吸与危重症医学科湖北武汉430071

目的:了解老年慢性阻塞性肺疾病(COPD)患者的营养状况及衰弱情况,探讨老年COPD营养风险的影响因素及其营养状况与衰弱的相关性。方法:采用便利抽样的方法,选取2021年12月—2022年12月在武汉大学中南医院住院的老年COPD患者为研究对象,... 详细信息

目的:了解老年慢性阻塞性肺疾病(COPD)患者的营养状况及衰弱情况,探讨老年COPD营养风险的影响因素及其营养状况与衰弱的相关性。方法:采用便利抽样的方法,选取2021年12月—2022年12月在武汉大学中南医院住院的老年COPD患者为研究对象,以营养风险筛查表(NRS2002)量表及FRAIL衰弱量表对老年COPD患者进行营养风险筛查及衰弱情况调查,并收集患者白蛋白、血清C反应蛋白指标,统计患者性别、年龄、体质量指数(BMI)、急性发病次数等参数。通过Kendall's tau-b分析患者衰弱状况与营养风险之间是否存在相关性,通过二分类Logistic回归来分析患者营养风险的影响因素。结果:120例老年COPD患者中,60.83%(73/120)的患者存在营养风险,65%(78/120)的患者存在衰弱,且其营养风险与衰弱存在正相关关系(r=0.739)。营养风险组患者的衰弱得分、白蛋白水平、BMI等低于无营养风险组患者,而平均年龄、血清C反应蛋白水平、1年内急性发病次数等高于无营养风险组患者,差异均有统计学意义(P<0.05)。衰弱状况、白蛋白水平、BMI、年龄、血清C反应蛋白与白蛋白比值(CAR)、急性发病次数等因素对老年COPD患者营养风险的发生有显著影响(P<0.05)。结论:老年COPD患者营养风险及衰弱发生率高,其营养风险与衰弱情况相关,医护人员应重点关注老年COPD患者营养状况、白蛋白水平及炎症指标,并实施阶段化干预措施,动态化营养管理,降低衰弱率,改善患者的营养状态。

关键词：慢性阻塞性肺疾病衰弱营养状况白蛋白血清C反应蛋白

CT图像肺结节计算机辅助检测与诊断技术研究综述

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数据采集与处理 2016年第5期31卷 868-881页

作者：伍长荣接标叶明全安徽师范大学数学计算机科学学院芜湖241002 皖南医学院计算机教研室芜湖241002

肺结节计算机辅助诊断(Computer-aided diagnosis,CAD)能够从CT图像中检测、分割和诊断肺结节,提高早期肺癌的生存率,因而具有重要临床意义。由于肺结节的形态根据其类型、尺寸、位置、内部结构及恶性与否等动态变化,导致肺结节检测和... 详细信息

肺结节计算机辅助诊断(Computer-aided diagnosis,CAD)能够从CT图像中检测、分割和诊断肺结节,提高早期肺癌的生存率,因而具有重要临床意义。由于肺结节的形态根据其类型、尺寸、位置、内部结构及恶性与否等动态变化,导致肺结节检测和诊断已经成为一个重大的挑战问题。本文对比分析了CAD系统中肺实质分割、肺结节检测、肺结节分割以及肺结节良恶性判断等4个步骤所运用的关键技术及挑战,并指出开发有效CAD系统需要进一步优化不同类型结节诊断算法灵敏度、降低结节检测误报数量、提高诊断自动化水平,同时需要集成影像存储与通信系统(Picture archiving and communication systems,PACS)以及电子病历系统(Electronic medical record systems,EMRS),以便在日常临床实践中应用。

关键词： CT图像肺结节计算机辅助检测与诊断医学图像处理与分析

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高校战略规划决策评价的多维度探析

高校教育管理 2017年第2期11卷 9-16页

作者：杨江水陈昌蓉吴家胤重庆师范大学发展规划处重庆401331

文章讨论了高校战略规划的五种内涵解释,认为规划有静态和动态之分。高校战略规划与决策的关系是辩证统一的,二者相互联系、相互依赖、相互补充,统一于大学组织的职能履行和发展中。高校战略规划决策评价应从四个维度来进行,即规划决策... 详细信息

文章讨论了高校战略规划的五种内涵解释,认为规划有静态和动态之分。高校战略规划与决策的关系是辩证统一的,二者相互联系、相互依赖、相互补充,统一于大学组织的职能履行和发展中。高校战略规划决策评价应从四个维度来进行,即规划决策分析的科学性、规划决策方案的可行性、规划决策实施的执行性和规划决策结果的有效性,从而更加科学有效地推进学校发展。

关键词：高校战略规划决策评价维度