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斜纹夜蛾核型多角体病毒DNA诱导同源昆虫细胞的凋亡

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生物化学与生物物理进展 2002年第4期29卷 592-596页

作者：杜昌升彭建新洪华珠华中师范大学昆虫学研究所武汉430079

发现野生型斜纹夜蛾核型多角体病毒 (Spodopteralituranuclearpolyhedrosisvirus ,SpltNPV)DNA转染SL 1细胞能诱导细胞凋亡 .SpltNPV DNA转染其同源细胞系斜纹夜蛾核SL 1细胞 6h后 ,光镜下即可见细胞膜表面突出或形成小泡 ,细胞碎裂成... 详细信息

发现野生型斜纹夜蛾核型多角体病毒 (Spodopteralituranuclearpolyhedrosisvirus ,SpltNPV)DNA转染SL 1细胞能诱导细胞凋亡 .SpltNPV DNA转染其同源细胞系斜纹夜蛾核SL 1细胞 6h后 ,光镜下即可见细胞膜表面突出或形成小泡 ,细胞碎裂成凋亡小体 ,18h后 ,细胞 10 0 %碎裂成凋亡小体 .DAPI荧光染色显示感染细胞核渐呈半月形 ,直至碎裂被凋亡小体包裹 .被转染的SL 1细胞DNA琼脂糖凝胶电泳呈典型梯形谱带 .野生型SpltNPV病毒粒子感染的SL 1细胞既无多角体的出现 ,也无凋亡现象的发生 .

关键词：斜纹夜蛾核多角体病毒 DNA 诱导同源昆虫细胞斜纹夜蛾细胞系细胞凋亡

Extramedullary plasmacytoma with the uvula as first affected site:A case report

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World Journal of Clinical Oncology 2025年第1期16卷 53-58页

作者： Jing Yang Hui peng sheng-Ke Tu Min Li Kui Song Department of Hematology The First Affiliated Hospital of Jishou UniversityJishou 416000Hunan ProvinceChina Department of Pharmacy The First Affiliated Hospital of Jishou UniversityJishou 416000Hunan ProvinceChina

BACKGROUND Extramedullary plasmacytoma(EMP)represents one of the rarer forms of plasma cell malignancies,capable of impacting a variety of tissues and organs throughout the *** majority of EMP cases are predominantly found in the head and neck region,especially within the laryngopharynx,as well as in the gastrointestinal *** there have been documented instances of oropharyngeal involvement in EMP cases in the academic literature,it is important to note that EMP specifically affecting the uvula is exceedingly ***,it is noteworthy that over 60% of epithelial carcinomas in the upper respiratory tract and oropharynx tend to metastasize to the cervical lymph nodes,indicating a propensity for regional spread in these types of *** this context,we present a rare case of extramedullary plasmacytoma where the uvula served as the initially affected *** case emphasizes the need for heightened awareness among clinicians regarding such unusual comorbidities,as early recognition and diagnosis can significantly influence patient management and treatment *** addition,a review of the relevant literature is included to further educate and inform healthcare professionals about this rare presentation,ultimately aiming to enhance clinical understanding and improve patient care in similar *** SUMMARY A 51-year-old man was admitted to our hospital because of a slowly enlarging neck mass.A physical examination revealed a palpable left lymph node,and magnetic resonance imaging(MRI)of the oropharynx and the neck showed a soft tissue mass in the oropharynx and enlargement of multiple lymph nodes in the *** soft tissue mass was diagnosed as plasmacytoma by immunohistochemical *** immunoglobulins and bone marrow biopsy showed normal ***,we diagnosed that as EMP of the *** four cycles of adjuvant chemotherapy dominated by bortezomib,MRI reexamination showed a significant reduction of the mass

关键词： Extramedullary plasmacytoma Plasmacytoma Uvula Multiple myeloma Case report

Apelin/APJ通路基因多态性与代谢综合征及apelin水平的关系

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中华高血压杂志 2017年第7期25卷 655-662页

作者：余明众黄澄渊许昌声彭峰林金秀福建医科大学附属第一医院心血管内科福建福州350005 福建省高血压研究所

目的探讨福建地区apelin/APJ通路基因多态性与代谢综合征(MS)及其相关组分以及血浆apelin的关系。方法纳入2015年2月至2016年2月福建医科大学附属第一医院心血管内科住院患者1018例,其中MS组457例,非MS组561例,酶联免疫吸附试验(ELISA)... 详细信息

目的探讨福建地区apelin/APJ通路基因多态性与代谢综合征(MS)及其相关组分以及血浆apelin的关系。方法纳入2015年2月至2016年2月福建医科大学附属第一医院心血管内科住院患者1018例,其中MS组457例,非MS组561例,酶联免疫吸附试验(ELISA)法检测血浆apelin36浓度,连接酶检测反应(LDR)探针法检测apelin/APJ基因分型。比较两组间等位基因频率分布情况、不同等位基因分组中各MS组分以及apelin浓度的差异性。结果男性MS受试者apelin基因rs3115757位点的C突变等位基因频率明显高于非MS组(P0.05)。结论 Apelin/APJ通路基因多态性与MS及血糖异常以及血浆apelin水平明显相关,并且存在性别差异。

关键词：代谢综合征 apelin/APJ通路单核苷酸多态性

Enhancing postoperative pain control by surgically-initiated rectus sheath block in abdominal aortic aneurysm open repair: A case report

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World Journal of Clinical Cases 2025年第6期13卷 41-47页

作者： Kuan-Hua Chen Ming-Yuan Kang Yi-Ting chang sheng-Yang Huang Yung-Szu Wu Center for Cardiovascular Disease Taichung Veterans General HospitalTaichung 407219TaiwanChina Department of Anesthesiology Taichung Veterans General HospitalTaichung 407219TaiwanChina Division of Pediatric Surgery Department of SurgeryTaichung Veterans General HospitalTaichung 407219TaiwanChina School of Medicine National Yang Ming Chiao Tung UniversityTaipei 112304TaiwanChina Department of Post-Baccalaureate Medicine National Chung Hsing UniversityTaichung 402202TaiwanChina

BACKGROUND Abdominal aortic aneurysm(AAA)repair often involves significant postoperative pain,traditionally managed with systemic opioids,which can cause undesirable side *** case report explores the novel use of a surgically-initiated rectus sheath block with a catheter-over-needle assembly for pain management in AAA *** SUMMARY A 67-year-old female with hypertension and previous aortic dissection underwent elective open repair of an infrarenal AAA,which had grown from 3.4 cm to 4.3 cm over 14 months.A rectus sheath block was initiated surgically for postoperative pain *** patient reported low pain scores and did not require systemic intravenous opioids,enabling early ambulation and discharge on postoperative day seven without *** preventing complications of systemic opi-oids,the method indicating a promising direction for postoperative pain management in major vascular *** Surgically-initiated rectus sheath block as a valuable tool for managing postoperative pain in AAA repair.

关键词： Abdominal aortic aneurysm Postoperative pain management Rectus sheath block Surgical anesthesia Opioid-sparing techniques Case report

Absorption and Fluorescence Emission Spectra of Molecules Containing Azo and/or Oxadiazole Units

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Chemical Research in Chinese Universities 2013年第4期29卷 776-781页

作者： WANG chang-sheng YU Nan LIU peng School of Chemistry and Chemical Engineering Liaoning Normal University Dalian 116029 P. R. China

The ground state structures of a series of organic molecules containing azo and/or oxadiazole units were obtained by means of density functional theory B3LYP/6-3IG（d） method. The first singlet excited state structures were optimized by virtue of singlet-excitation configuration interaction CIS/6-31G（d） method. The absorption and fluorescence emission spectra were then evaluated via the time-dependent density functional theory B3LYP and PBE1PBE methods with 6-31 l＋＋G（3df,2p） basis set. The calculation results show that compared with those of their parent molecules A-H, B-H, C-H, D-H, the absorption and emission wavelength values of all the derivatives show red shifts. The derivatives containing both the oxadiazole and methoxyl units are good candidates for longer absorption wavelength materials. The effects of azo, oxadiazole, and methoxyl units on the absorption and emission wavelength were discussed.

关键词： Azo Azobenzene Oxadiazole Absorption spectrum Fluorescence emission spectrum Excited state

Light-Responsive Nanomaterials for Cancer Therapy

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Engineering 2022年第6期8卷 18-30页

作者： Xu Zhang sheng Wang Guohui Cheng peng Yu Jin chang School of Life Sciences Tianjin UniversityTianjin 300072China Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin 300072China

Due to its unique advantages,which include minimal invasiveness and relative clinical safety,photother-apy is considered to be a promising approach for cancer ***,the treatment efficacy of phototherapy is often restricted by the limited depth of light penetration and the low targeting effect of phototherapeutic *** emergence of light-responsive nanomaterials offers a possible approach to achieve enhanced phototherapy *** review summarizes the progress in biomedical applica-tions of light-responsive nanomaterials for cancer therapy,which include photothermal therapy(PTT),photodynamic therapy(PDT),light-responsive molecule delivery,and light-controlled combination *** prospects are also *** review aims to demonstrate the significance of light-responsive nanomaterials in cancer therapy and to provide strategies to expand the applications of phototherapy.

关键词： Light-responsive Nanomaterials Cancer Phototherapy

The effects of hydrogen on the helium behavior in palladium

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Nuclear Science and Techniques 2016年第5期27卷 114-119页

作者： chang-Ning peng Electrical Engineering College Longdong University

As one candidate of tritium storage materials,palladium subjects to the damage from helium atoms introduced by the(3-decay of tritium *** mechanical properties of palladium will be greatly degraded deriving from the accumulation of helium atoms.A set of interatomic potentials has been fitted based on ab initio calculation according to the Morse *** dynamic methods are utilized to investigate the existence of H atoms on the release of helium atoms from palladium with the present fitted *** is found that hydrogen atoms play significant roles in the diffusion and release of helium *** presence of hydrogen atoms tends to obstacle the diffusion and release of helium atoms in palladium.

关键词：氦原子氢原子行为钯分子动力学存储材料机械性能莫尔斯

Spherical modification of tungsten powder by particle composite system

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Rare Metals 2022年第6期41卷 1972-1976页

作者： Cong-Cong Wang Cheng-chang Jia peng Gao Guo-sheng Gai Yu-Fen Yang School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China Powder Technology R&D Group Department of Material Science and EngineeringTsinghua UniversityBeijing 100084China

Owing to contradiction between increasing demand of spherical tungsten powder and limitation of traditional manufacturing technology,a novel preparation method was developed to sphericize the polygonal tungsten powder by means of modification of particle composite *** powder particles were modified by par-ticle composite system,and detailed characterization by scanning electron microscopy(SEM)was *** size distribution and function mechanism were analyzed,and the internal relationship between average diameter and processing time was *** results show that the spherical tungsten powder with an average diameter of 6.41μm is obtained from polyhedral tungsten powder with an average diameter of 7.50μ*** spherical effect could be achieved(sharp edge angles of particles are rounded off and reshaped)when the processing time is over 30 *** relationship between average diameter(d)and pro-cessing time can be described by the exponential decay model,which provides a good interpretation for the process of *** relationship between them can be expressed by the equation d=1.87406exp(-x/8.92718)+*** proposed method could readily enable large-scale production of spherical tungsten powder.

关键词： Tungsten powder Modification Average diameter Powder metallurgy

Tetra-detector size exclusion chromatography characterization of molecular and solution properties of soluble microbial polysaccharides from an anaerobic membrane bioreactor

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Frontiers of Environmental Science & Engineering 2017年第2期11卷 165-174页

作者： Qingbin Guo sheng chang School of Engineering University of Guelph Guelph Ontario N 1G 2W1 Canada

Characterization of the molecular properties of soluble microbial products （SMP） is critical for understanding the membrane filtration and fouling mechanisms in anaerobic and aerobic membrane bioreactors （AnMBR ＆ MBR）. In this study, the distributions of the absolute molecular weight and intrinsic viscosity of SMP polysaccharides from an AnMBR were effectively determined by a high pertbrmance size exclusion chromatography （HPSEC） that was coupled with the refractive index （RI）,cliode array UV （DAUV）, right and low angle light scattering （LS）, and viscometer （Vis） detectors. Based on the tetra-detector HPSEC determined absolute molecular weights and intrinsic viscosity, a universal calibration relationship for the SMP polysaccharides was developed and the molecularconformations, average molecular weights~ and hydrodynamic sizes of the SMP polysaccharides were also explored. Two factors which can be derived from the tetra-detector HPSEC analysis were proposed for the characterization of the viscous and osmotic pressure properties of the SMP polysaccharides. In addition, it was also extrapolated how to analyze the resistance characteristics of the concentration polarization layers formed in membrane filtration based on the molecular properties determined by the tetra-detector HPSEC analysis.

关键词： Soluble microbial productExtracellular polymeric substanceMembrane bioreactorMembrane foulingMolecular weightIntrinsic viscosity