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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2015年第1期16卷 78-86页

作者： Hui-yong PENG chang-feng man Juan XU Yu FAN Cancer Institute the Affiliated People's Hospital Jiangsu University

Objective： To investigate whether elevated homocysteine levels were a predictor of subsequent coronary heart disease （CHD） mortality, cardiovascular mortality or all-cause mortality in the general population by a meta- analysis. Methods： In a systematic search conducted in the databases of PubMed and Embase prior to October 2013, we identified relevant prospective observational studies evaluating the association between baseline homocysteine levels and CHD mortality, cardiovascular or all-cause mortality in the general population. Pooled adjust risk ratio （RR） and corresponding 95% confidence interval （CI） were calculated separately for categorical risk estimates and con- tinuous risk estimates. Results： Twelve studies with 23 623 subjects were included in the meta-analysis. Comparing the highest to lowest homocysteine level categories, CHD mortality increased by 66% （RR 1.66; 95% CI 1.12-2.47; P=-0.012）, cardiovascular mortality increased by 68% （RR 1.68; 95% CI 1.04-2.70; P=0.033）, and all-cause mortality increased by 93% （RR 1.93; 95% CI 1.54-2.43; P〈0.001）. Moreover, for each 5 pmol/L homocysteine increment, the pooled RR was 1.52 （95% CI 1.26-1.84; ,〈0.001） for CHD mortality, 1.32 （95% CI 1.08-1.61; P=0.006） for cardio- vascular mortality, and 1.27 （95% CI 1.03-1.55; P=-0.023） for all-cause mortality. Conclusions： Elevated homocysteine levels are an independent predictor for subsequent cardiovascular mortality or all-cause mortality, and the risks were more pronounced among elderly persons.

关键词： Homocysteine Coronary heart disease Cardiovascular mortality All-cause mortality Meta-analysis

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基于半监督协同训练的无人机对地目标跟踪

激光与红外 2017年第6期47卷 778-782页

作者：毛盾邢昌风满欣付峰海军工程大学电子工程学院中国人民解放军91208部队

由于目标小、可区分性差,无人机对地目标跟踪较传统视频目标跟踪更容易丢失目标,提出一种基于l_1图半监督协同训练的目标跟踪算法。算法首先提取样本的颜色和纹理特征构建两个充分冗余的视图,再以基于l_1图的半监督学习算法取代传统协... 详细信息

由于目标小、可区分性差,无人机对地目标跟踪较传统视频目标跟踪更容易丢失目标,提出一种基于l_1图半监督协同训练的目标跟踪算法。算法首先提取样本的颜色和纹理特征构建两个充分冗余的视图,再以基于l_1图的半监督学习算法取代传统协同训练中的监督学习方法构建单视图中的分类器,提高有限标记样本条件下的分类正确率,然后通过基于负类学习的协同训练算法协同更新两个视图的分类器,最后根据不同视图的相似度分布熵融合各分类器的分类结果实现目标跟踪。实验结果表明,该算法能够有效提高分类器的判别能力,具有良好的跟踪性能。

关键词：目标跟踪 l1图基于图的半监督学习多视图协同训练无人机

Asymptotic false discovery control of the Benjamini-Hochberg procedure for pairwise comparisons

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Science China Mathematics 2025年第1期 223-252页

作者： Weidong Liu Dennis Leung Qi-man Shao School of Mathematical Sciences Shanghai Jiao Tong University School of Mathematics and Statistics University of Melbourne Department of Statistics and Data Science SICMSouthern University of Science and Technology

In a one-way analysis-of-variance(ANOVA) model,the number of pairwise comparisons can become large even with a moderate number of *** by this,we consider a regime with a growing number of groups and prove that,when testing pairwise comparisons,the Benjamini-Hochberg(BH) procedure can asymptotically control false discoveries,despite the fact that the involved t-statistics do not exhibit the wellknown positive dependence structure required for exact false discovery rate(FDR) *** Tukey's perspective that the difference between the means of any two groups cannot be exactly zero,our main result provides control over the directional false discovery rate and directional false discovery proportion.A key technical contribution of our work is demonstrating that the dependence among the t-statistics is sufficiently weak to establish the convergence result typically required for asymptotic FDR *** analysis does not rely on conventional assumptions such as normality,variance homogeneity,or a balanced design,thereby offering a theoretical foundation for applications in more general settings.

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公路施工中振动搅拌水泥稳定碎石的应用研究

工程建设与设计 2023年第4期 124-126页

作者：刘涛冯昌满王理波肖玉杰周张峰中交一航局第五工程有限公司河北秦皇岛066000

针对公路施工中水泥稳定碎石的搅拌技术应用等问题,以平南高速公路工程项目No.2标合同段为例,研究水泥稳定碎石振动搅拌技术的应用要点与应用效果。解决了水稳碎石混合料搅拌技术落后、性能质量不佳的问题,在对比普通搅拌技术与振动搅... 详细信息

针对公路施工中水泥稳定碎石的搅拌技术应用等问题,以平南高速公路工程项目No.2标合同段为例,研究水泥稳定碎石振动搅拌技术的应用要点与应用效果。解决了水稳碎石混合料搅拌技术落后、性能质量不佳的问题,在对比普通搅拌技术与振动搅拌技术应用成效基础上,分析振动搅拌技术应用优势。结果表明,应用振动搅拌技术能有效提升水稳碎石混合料的抗压强度,并降低其变异系数。

关键词：公路施工振动搅拌水泥稳定碎石

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： man Han Deyang Zeng Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen Zhen Wei Yufei Mei Yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第01期 288-296页

作者： Shuai Liu Wen-Qiang Xu Ying-Tong Di man-Cheng Tang Ding-Kang Chen Ming-Ming Cao Yao-Wen chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu Xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

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基于隐性句逗号识别的汉语长句机器翻译

外语学刊 2025年第1期 39-46页

作者：冯文贺李熳佳张文娟广东外语外贸大学外国语言学及应用语言学研究中心语言工程与计算实验室广州510420 广州理工学院计算机科学与工程学院广州510420

长句翻译一直是机器翻译的难题。本文根据汉语中相当数量的逗号和句号可相互转化的特点,提出“隐性句号”和“隐性逗号”概念,并实现其自动识别,以将汉语长句变为短句用于汉英机器翻译。为此,首先通过人工与半监督学习结合方法构建一个... 详细信息

长句翻译一直是机器翻译的难题。本文根据汉语中相当数量的逗号和句号可相互转化的特点,提出“隐性句号”和“隐性逗号”概念,并实现其自动识别,以将汉语长句变为短句用于汉英机器翻译。为此,首先通过人工与半监督学习结合方法构建一个隐性句逗数据集,实现基于预训练模型的隐性句逗识别方法,其中性能最好的Hierarchical BERT作为后续应用模型。进而,实现基于隐性句逗识别的汉英机器翻译方法。在新闻和文学公开翻译测试语料上基于预训练机器翻译模型的实验表明,对于汉语长句的英译,本文方法相比基准翻译的BLEU值整体有所提高,而且在相对稳健机器翻译模型上,呈现为句子越长本文方法效果越明显。

关键词：机器翻译长句翻译隐性句逗号汉语长句逗号识别句内标点

Studies on Lead Tungstate Crystal

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Chinese Physics Letters 1998年第1期15卷 46-47页

作者： LIU feng-zhen HAN Jian-ru man chang-feng CHEN Huan-chu HE Mao Department of Physics Shandong UniversityJi’nan 250100 Institute of Crystal Materials Shandong UniversityJi’nan 250100

The growth of lead tungstate(PWO)single crystals and their luminescence properties such as light yield,scintillation decay time,and transmittance were *** colourless PWO single crystal has been obtained by using the presyntheses ***,Nb,and Mg ions were doped in the crystals and the Ba-doped crystal has a relatively short decay *** crystal was found having a better transmission spectrum than that of unannealed one.

关键词： crystal decay annealed

Azobenzene/graphene hybrid for high-density solar thermal storage by optimizing molecular structure

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Science China(Technological Sciences) 2016年第9期59卷 1383-1390页

作者： LI man[[ feng YiYu[[ LIU EnZuo QIN ChengQun[[ feng Wei[[ School of Materials Science and Engineering Tianjin University Tianjin 300072 China Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072 China Key Laboratory of Advanced Ceramics and Machining Technology Ministry of Education Tianjin 300072 China Tianjin Key Laboratory of Composite and Functional Materials Tianjin 300072 China

A large capacity storing solar energy as latent heat in a close-cycle is essentially important for solar thermal fuels. This paper presents a solar thermal molecule model of a photo-isomerizable azobenzene(Azo) molecule covalently bound to graphene. The storage capacity of the Azo depending on isomerization enthalpy(ΔH) is calculated based on density functional theory. The result indicates that the ΔH of Azo molecules on the graphene can be tuned by electronic interaction, steric hindrance and molecular hydrogen bonds(H-bonds). Azo with the withdrawing group on the ortho-position of the free benzene shows a relatively high ΔH due to resonance effect. Moreover, the H-bonds on the trans-isomer largely increase ΔH because they stabilize the trans-isomer at a low energy. 2-hydroxy-4-carboxyl-2′,6′,-dimethylamino-Azo/graphene shows the maximum ΔH up to 1.871 e V(107.14 Wh kg^(-1)), which is 125.4% higher than Azo without functional groups. The Azo/graphene model can be used for developing high-density solar thermal storage materials by controlling molecular interaction.

关键词： solar thermal energy storage azobenzene graphene hydrogen bonds density functional theory

Self-normalized Cramer-type Moderate Deviations for Functionals of Markov Chain

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Acta Mathematicae Applicatae Sinica 2020年第2期36卷 294-313页

作者： Xin-wei feng Qi-man SHAO Zhongtai Securities Institute for Financial Studies Shandong UniversityJinan 250100China Department of Statistics The Chinese University of Hong KongShatinN.T.Hong KongChina Department of Statistics and Data Science Southern University of Science and TechnologyShenzhen 518000China

Let{xn,n≥0}be a Markov chain with a countable state space S and let f(·)be a measurable function from S to R and consider the functionals of the Markov chain yn:=f(xn).We construct a new type of self-normalized sums based on the random-block scheme and establish a Crame′r-type moderate deviations for self-normalized sums of functionals of the Markov chain.

关键词： self-normalized partial sums Cramer-type moderate deviations Markov Chain ergodic