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Genes & Diseases 2024年第5期11卷 63-65页

作者： Bo Liang Rui Dong Sze Wan hung Yiran Li yuezhen Lin Ling Wu Tao Zhang Gene Chi Wai Man Hui Xu Jacqueline Pui Wah Chung Chi Chiu Wang Guangdong Provincial Key Laboratory of Marine Biotechnology Institute of Marine SciencesShantou UniversityShantouGuangdong 515063China Department of Obstetrics and Gynaecology The Chinese University of Hong KongHong Kong SARChina Reproduction and Development Laboratory Li Ka Shing Institute of Health SciencesThe Chinese University of Hong KongHong Kong SARChina School of Biomedical Sciences The Chinese University of Hong KongHong Kong SARChina Chinese University of Hong Kong-Sichuan University Joint Laboratory in Reproductive Medicine The Chinese University of Hong KongHong Kong SARChina

Endometriosis is a common and benign angiogenesisdependent gynecological disorder,which refers to the proliferation and growth of endometrium-like tissues with neovasculature formation outside of the uterus.1 Available medical treatments for endometriosis containing hormonal and non-hormonal treatments had been limited for longterm usage by their side effects.2 Ideal medical treatment for endometriosis with efficacy to relieve symptoms and suppress endometriotic lesion growth and minimal side effects has been longing for decades.3 Angiogenesis is a promising therapeutic target for endometriosis.

关键词： therapeutic endometriosis herbal

Comparative Chemical Research in Essential Oils from Six Apiaceae Species Growing in the Northern Region of Vietnam

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1677-1687页

作者： Nguyen Quang hung Nguyen Thanh Tung Nguyen Phuong Hanh Chu Thi Thu Ha Nguyen Thi Nhung Nguyen Thai An Vu Xuan Giang Luong Van Hao Oleh Koshovyi Ain Raal Institute of Ecology and Biological Resources Vietnam Academy of Science and Technology(VAST)Cau GiayHa Noi100000Viet Nam Graduate University of Science and Technology Vietnam Academy of Science and Technology(VAST)Cau GiayHa Noi100000Viet Nam Department of Pharmacognosy Faculty of Pharmacognosy and Traditional MedicineHanoi University of PharmacyHoan KiemHa Noi100000Viet Nam Sa Pa Research Center of Medicinal Materials National Institute of Medicinal MaterialsDien Bien PhuSa PaLao Cai330000Viet Nam Institute of Pharmacy Faculty of MedicineUniversity of TartuTartu50411Estonia

Our study aimed to compare the essential oil(EO)concentration and composition of several Apiaceae species growing in the Northern region of *** yields of EOs from materials ranged from 0.03%(root EO of Angelica acutiloba and aerial parts EO of Heracleum bivittatum)-0.27%(leaf EO of Xyloselinum vietnamense).Gas chromatography-mass spectrometry(GC-MS)allowed the identiﬁcation of 74 components in the EOs of six Apiaceae species,making up 94.4%–100.0%of the *** EO from Angelica acutiloba,(Z)-ligustilide accounted for an extremely large proportion(94.9%).EO of Angelica pubescens was dominated by six character-istic components includingα-pinene(21.5%),β-phellandrene(18.1%),p-cymene(12.2%),3-methylnonane(8.7%),o-cymene(8.1%),and D-sylvestrene(6.2%).The EO from Cryptotaenia japonica was characterized by high amounts ofα-selinene(48.7%),β-selinene(23.7%),and trans-β-farnesene(5.4%).The EOs from leaves and stems of Xyloselinum vietnamense were characterized by high concentrations of sabinene(69.8%and 33.8%),4-terpineol(8.7%and 7.4%)andβ-pinene(4.0%and 6.5%)while EOs from aerial parts and root of Xylo-selinum leonidii comprise four characteristic monoterpenes includingα-pinene(28.2%and 52.8%),β-pinene(7.9%and 10.3%),β-phellandrene(7.6%and 15.3%),and sabinene(3.0%and 4.1%).Additionally,cryptone is also one of the major components in the EO of Xyloselinum leonidii(13.2%in the aerial parts oil and 2.8%in the root oil).In the EOs isolated from the aerial parts and root of Heracleum bivittatum,α-pinene(22.5%and 70.2%)andβ-pinene(43.2%and 20.0%)were the predominant *** appeared in the EO from aerial parts of Heracleum bivittatum with a relatively high concentration(13.5%)while bornyl acetate(5.1%)was also one of the main components in the EO from its aerial parts but was not detected in other Apiaceae species in the present *** databases help identify and control the quality of plant material studied from the family Apiaceae growing in Vietnam.

关键词： Apiaceae essential oil terpenoids gaschromatography-mass spectrometry

IgG4 Coronary Arteritis Presenting as a Cardiac Pseudo-Tumour

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Case Reports in Clinical Medicine 2024年第9期13卷 345-352页

作者： Elaine Mo-Chee Chau Catherine yuet-hung Wong Raymond Hin-Suen Liang Cardiology Centre Hong Kong Sanatorium & Hospital Hong Kong SAR China Nuclear Medicine Department Hong Kong Sanatorium & Hospital Hong Kong SAR China Comprehensive Oncology Centre Hong Kong Sanatorium & Hospital Hong Kong SAR China

We report on an unusual case presenting with a cardiac pseudo-tumour on echocardiogram, which corresponded to a large soft tissue mural thickening around the mid-right coronary artery. There were similar but not as thick mural lesions around other parts of the coronary arteries. The so-called “pigs-in-a-blanket” sign on computed tomography (CT) scan was pathognomonic of IgG4 coronary arteritis. The IgG4 level was grossly elevated at more than 10 times the upper limit of normal. Positron emission tomography (PET)-CT scans with 18F-fluoro-deoxy-glucose (FDG) and 68Ga-Fibroblast Activation Protein Inhibitor (FAPI) were performed to assess the extent of organ involvement of the IgG4-related disease. The patient was treated with 8 injections of rituximab with good serological response. However, the coronary arteritis findings on CT scan remained unchanged.

关键词： IgG4-Related Disease Coronary Arteritis Cardiac Pseudo-Tumour “Pigs-in-a-Blanket” Sign

Riding towards a sustainable future:an evaluation of bike sharing’s environmental benefits in Xiamen Island,China

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Geography and Sustainability 2024年第2期5卷 276-288页

作者： Jianxiao Liu Meilian Wang Pengfei Chen Chaoxiang Wen yue yu KW Chau Department of Real Estate and Construction Faculty of ArchitectureThe University of Hong KongPokfulamHong Kong 999077China Department of Land Surveying and Geo-informatics The Hong Kong Polytechnic UniversityHung HomHong Kong 999077China School of Geospatial Engineering and Science Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Department of Urban Planning School of Architecture and Civil EngineeringXiamen UniversityXiamen 550002China Ronald Coase Centre for Property Rights Research HKUrbanLabThe University of Hong KongPokfulamHong Kong 999077China

In the pursuit of sustainable urbanization,Bike-Sharing Services(BSS)emerge as a pivotal instrument for promoting green,low-carbon *** BSS is often commended for its environmental benefits,we offer a more nuanced analysis that elucidates previously neglected *** the Dominant Travel Distance Model(DTDM),we evaluate the potential of BSS to replace other transportation modes for specific journey based on travel *** multiscale geographically weighted regression(MGWR),we illuminate the relationship between BSS’s environmental benefits and built-environment *** life cycle analysis(LCA)quantifies greenhouse gas(GHG)emissions from production to operation,providing a deeper understanding of BSS’s environmental ***,our study focuses on Xiamen Island,a Chinese“Type Ⅱ large-sized city”(1–3 million population),contrasting with the predominantly studied“super large-sized cities”(over 10 million population).Our findings highlight:(1)A single BSS trip in Xiamen Island reduces GHG emissions by an average of 19.97 g CO_(2)-eq,accumulating monthly savings of 144.477 t CO_(2)-eq.(2)Areas in the southwest,northeast,and southeast of Xiamen Island,characterized by high population densities,register significant BSS environmental benefits.(3)At a global level,the stepwise regression model identifies five key built environment factors influencing BSS’s GHG mitigation.(4)Regionally,MGWR enhances model precision,indicating that these five factors function at diverse spatial scales,affecting BSS’s environmental benefits variably.

关键词： Greenhouse gases Shared mobility Carbon emission Multiscale geographically weighted regression Travel behavior Urban mobility

Effects of synthetic site water on bentonite-concrete system for a potential nuclear waste repository

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3786-3797页

作者： Zhao Sun Yong-Gui Chen Wei-Min Ye Qiong Wang Dong-Bei Wu Zhen-yu Yin Key Laboratory of Geotechnical and Underground Engineering of Ministry of Education Department of Geotechnical EngineeringTongji UniversityShanghai200092China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina School of Chemical Science and Engineering Tongji UniversityShanghai200092China

In high-level nuclear waste(HLW)repositories,concrete and compacted bentonite are designed to be employed as buffer materials,which may raise a problem of interactions between concrete and *** interactions would lead to mineralogy transformation and buffer performance decay of bentonite under the near field environment conditions in a repository.A small-scale experimental setup was established to simulate the concrete-bentonite-site water interaction system from a potential nuclear waste repository in *** types of mortars were prepared to correspond to the concrete at different degradation *** results permit the determination of the following:(1)The macroproperties of Gaomiaozi(GMZ)bentonite(*** pressure,permeability,the final dry density,and water content of reacted samples);(2)The composition evolution of fluids from the synthetic site water-concrete-bentonite interaction systems;(3)The sample characterization including Fourier transform infrared spectroscopy(FTIR)and X-ray powder diffraction(XRD).Under the infiltration of the synthesis Beishan site water(BSW),the swelling pressure of bentonite decreases slowly with time after reaching its second swelling *** flux decreases with time during the infiltrations,and it tends to be stable after more than 120 *** to the cation exchange reactions in the BSW-concrete-bentonite systems,the divalent cations(Ca and Mg)were consumed,and the monovalent cations(Na and K)were *** dissolution of minerals in the bentonite such as albite causes Si increasing in the pore *** was concluded that the hydro-mechanical property degradation of bentonite takes place when it comes into contact with concrete mortar,even under low-pH groundwater *** soil dispersion,the uneven water content,and the uneven dry density in bentonite samples may partly contribute to the swelling decay of ***,the direct contact with concrete has an obvious effect on the performance

关键词： Mock-up device GMZ bentonite Site water-concrete-bentonite system Geochemistry Buffer performance

lahysiological links of circadian clock and biological clock of aging

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Protein & Cell 2017年第7期8卷 477-488页

作者： Fang Liu hung-Chun chang Institute of Neuroscience State Key Laboratory of Neuroscience Key Laboratory of Primate Neurobiology CAS Center for Excellence in Brain Science and Intelligence Technology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai 200031 China University of Chinese Academy of Sciences Shanghai 200031 China

Circadian rhythms orchestrate biochemical and physi-ological processes in living organisms to respond the day/night cycle. In mammals, nearly all cells hold self- sustained circadian clocks meanwhile couple the intrinsic rhythms to systemic changes in a hierarchical manner. The suprachiasmatic nucleus （SCN） of the hypothalamus functions as the master pacemaker to initiate daily synchronization according to the photope-riod, in turn determines the phase of peripheral cellular clocks through a variety of signaling relays, including endocrine rhythms and metabolic cycles. With aging, circadian desynchrony occurs at the expense of peripheral metabolic pathologies and central neurode- generative disorders with sleep symptoms, and genetic ablation of circadian genes in model organisms resem- bled the aging-related features. Notably, a number of studies have linked longevity nutrient sensing pathways in modulating circadian clocks. Therapeutic strategies that bridge the nutrient sensing pathways and circadian clock might be rational designs to defy aging.

关键词： circadian rhythms SCN longevity

Design of a long range nano-scale resolution mechanism

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2010年第4期11卷 250-254页

作者： Shuo hung chang Jen Bon LEE Department of Mechanical Engineering National Taiwan University

This paper presents the development of a coarse-fine dual precision positioning stage to achieve long travel range and high *** fine stage is arranged in series with a coarse *** key in the fine stage design is the choice of a toggle mechanism for a tight mechanical loop with high stiffness and *** designed the toggle mechanism for reduction of the displacement to suppress signal *** performance of the coarse and fine stages was verified with an optical encoder and capacitive sensor,*** measurement results show that the dual mechanism has a travel range of 1 mm and resolution of 30 nm.

关键词： Coarse-fine dual stage Nano-scale resolution Piezoelectric (PZT) actuator

妖物與特務:明代成化朝的訊息掌控與政治操作

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文史 2024年第1期 188-223页

作者：王鴻泰 “中央研究院”歷史語言研究所

本文探討訊息傳播與政治操作之間的密切關係,考察其所牽涉之不同層面與内容。一般認爲,明朝特務政治乃受寵宦官藉以整肅異己之惡政。然而,這一情報系統如何在政治場域生根、發展與發揮作用,以及如何因應現實而調整,則多不甚了了。今由... 详细信息

本文探討訊息傳播與政治操作之間的密切關係,考察其所牽涉之不同層面與内容。一般認爲,明朝特務政治乃受寵宦官藉以整肅異己之惡政。然而,這一情報系統如何在政治場域生根、發展與發揮作用,以及如何因應現實而調整,則多不甚了了。今由訊息掌控角度切入,考察情報與政治之關係。明朝自正統以來,政治情勢與訊息掌控關係密切,尤其成化朝之後,訊息的流動與掌控異常敏感,直接牽動政局。皇帝委任親信建立情報偵察系統,並刻意强化對訊息流通的控制;而儒臣群體則傾向於傳播訊息,公開討論,藉以製造輿論。訊息的傳播與控制成爲不同權位者角力、鬥争的攻防要地,甚至可以説政治操作的重要戰場就在訊息的掌控上。自此政治操作愈發複雜,除了表面的政見闡述與職權分配外,訊息掌控更屬要義。在政治場合中,訊息的搜集、利用、詮釋,乃至編造,已成爲重要的政治技藝。

关键词：妖言廠衞黑眚汪直

Status and progress of metal-supported solid oxide fuel cell: Towards large-scale manufactory and practical applications

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Energy Reviews 2024年第1期3卷 1-23页

作者： Haoran Xu yu Han Jing Zhu Meng Ni Zhen Yao State Key Laboratory of Clean Energy Utilization Zhejiang University38 Zheda RoadHangzhou310027China Department of Building and Real Estate Research Institute for Sustainable Urban Development(RISUD)&Research Institute for Smart Energy(RISE)Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Fakultät für Physik Universität BielefeldUniversitätsstr.2533615BielefeldGermany

Metal-supported solid oxide fuel cells(MS-SOFCs)own advantages of high performance,fast start-up,thermal cycle stability,easy sealing,and reduced material *** recent years,significant progress has been made in the development of MS-SOFCs,particularly with respect to improved electrochemical performance,long-term stability,and industrial *** studies have mainly focused on stainless steel-based MS-SOFCs,with an emphasis on the development of low-temperature preparation processes,antioxidant coatings,stable electrodes,and the direct utilization of hydrocarbon ***,Ceres Power and GE have successfully commercialized MS-SOFCs and have constant cooperated with several institutions and companies,such as Jülich Research Center,Weichai and Cummins,to promote the performance and expand the market of *** ahead,this review paper provides an outlook on future research directions in this rapidly evolving field.

关键词： Metal support Solid oxide fuel cell High performance Long-term stability

A FRAMEWORK OF SETTING UP GOAL CONTROL LIMITS OF TARGET COSTING FOR NON-NORMAL DISTRIBUTIONS

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Journal of Systems Science and Systems Engineering 2007年第4期16卷 424-433页

作者： Hsin-hung WU Fong-Jung yu Department of Business Administration National Changhua University of Education Changhua Taiwan China Department of Industrial Engineering and Technology Management Da-Yeh University Changhua Taiwan China

This study provides a framework of target costing to extend its original scope when the underlying distribution is non-normal. The new specification limits can be derived by listening to the market price from Taguchi loss function. Later, the new specification limits can be linked through the non-normality-based C^^pk value along with non-normality-based X^^-Rcontrol charts to derive goal control limits. Moreover, an example is provided to illustrate the usefulness of the proposed framework of target costing by relentlessly reducing cost and improving product quality to gain competitiveness in the marketplace.

关键词： Target costing Taguchi loss function goal control limit process capability index non-normal distribution