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Preoperative blood markers and intra-abdominal infection after colorectal cancer resection

World Journal of Gastrointestinal Surgery 2024年第2期16卷 451-462页

作者： chang-qing liu Zhong-Bei Yu Jin-Xian Gan Tian-Ming Mei Department of Gastrointestinal Anorectal Surgery Suzhou Hospital Affiliated to Anhui Medical UniversitySuzhou 234000Anhui ProvinceChina

BACKGROUND Colorectal cancer(CRC)has one of the highest morbidity and mortality rates among digestive tract ***-abdominal infection(IAI)is a common postoperative complication that affects the clinical outcomes of patients with CRC and hinders their rehabilitation ***,the factors influencing abdominal infection after CRC surgery remain unclear;further,prediction models are rarely used to analyze preoperative laboratory indicators and postoperative *** To explore the predictive value of preoperative blood markers for IAI after radical resection of *** The data of 80 patients who underwent radical resection of CRC in the Anorectal Surgery Department of Suzhou Hospital affiliated with Anhui Medical University were *** patients were categorized into IAI(n=15)and non-IAI groups(n=65)based on whether IAI *** factors were compared;general data and laboratory indices of both groups were *** relationship between the indicators was ***,a nomogram prediction model was developed and evaluated;its utility and clinical applic-ability were *** The risk factors for IAI after radical resection of CRC were neutrophil-lymphocyte ratio(NLR),platelet-lymphocyte ratio(PLR),systemic immune-inflammation index(SII),and carcinoembryonic antigen(CEA)*** was correlated with PLR and SII(r=0.604,0.925,and 0.305,respectively),while PLR was correlated with SII(r=0.787).The nomogram prediction model demonstrated an area under the curve of 0.968[95%confidence interval(CI):0.948-0.988]in the training set(n=60)and 0.926(95%CI:0.906-0.980)in the validation set(n=20).The average absolute errors of the calibration curves for the training and validation sets were 0.032 and 0.048,respectively,indicating a good model *** decision curve analysis curves demonstrated high net income above the 5%threshold,indicating the clinical practicality of the *** The nomogram model constructed

关键词： Radical resection of colorectal cancer Inflammatory factors Intra-abdominal infection Predictive model Blood markers

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Effects of Homogeneous Plasma on Strong Gravitational Lensing of Kerr Black Holes

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Chinese Physics Letters 2017年第9期34卷 24-28页

作者： chang-qing liu Chi-Kun Ding Ji-Liang Jing Department of Physics Hunan University of Humanities Science and Technology Loudi 417000 Department of Physics and Key Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of Education Hunan Normal University Changsha 410081

Considering the Kerr black hole surrounded by a homogeneous unmagnetized plasma medium, we study the strong gravitational lensing on the equatorial plane of the Kerr black hole. It is found that the presence of the uniform plasma can increase the photon-sphere radius r_{／rm ps}, the coefficients ／bar{a} and ／bar{b}, the angular position of the relativistic images （／theta_{／infty}）, the deflection angle ／alpha（／theta） and the angular separation s. However, the relative magnitude r_{／rm m} decreases in the presence of the uniform plasma medium. It is also shown that the impact of the uniform plasma on the effect of strong gravitational lensing becomes smaller as the spin of the Kerr black hole increases in the prograde orbit （a〉0）. In particular, for the extreme black hole （a=0.5）, the effect of strong gravitational lensing in the homogeneous plasma medium is the same as the case in vacuum for the prograde orbit.

关键词： Effects of Homogeneous Plasma on Strong Gravitational Lensing of Kerr Black Holes

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Periodic Orbits Around Kerr Sen Black Holes

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Communications in Theoretical Physics 2019年第12期71卷 1461-1468页

作者： chang-qing liu Chi-Kun Ding Ji-Liang Jing Department of Physics Hunan University of Humanities Science and TechnologyLoudi 417000China Department of Physics and Key Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of EducationHunan Normal UniversityChangsha 410081China

We investigate periodic orbits and zoom-whirl behaviors around a Kerr Sen black hole with a rational number q in terms of three integers(z,w,v),from which one can immediately read off the number of leaves(or zooms),the ordering of the leaves,and the number of *** characteristic of zoom-whirl periodic orbits is the precession of multi-leaf orbits in the strong-field *** feature is analogous to the counterpart in the Kerr ***,we analyze the impact of the charge parameter b on the zoom-whirl periodic *** to the periodic orbits around the Kerr black hole,it is found that typically lower energies are required for the same orbits in the Kerr Sen black hole.

关键词： periodic orbits Kerr Sen black hole zoom-whirl rational number

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Vertically grown MoS_(2)nanosheets on graphene with defect-rich structure for efficient sodium storage

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Rare Metals 2024年第3期43卷 1062-1071页

作者： Ying Wang Jia-Peng He Han-qing Pan qing-Peng Wang Lei Zhang Yong-chang liu qing-Hong Wang School of Chemistry&Materials Science Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional MaterialsJiangsu Normal UniversityXuzhou221116China Institute of Biopharmaceutical Research Liaocheng UniversityLiaocheng252059China Beijing Advanced Innovation Center for Materials Genome Engineering Institute for Advanced Materials and TechnologyState Key Laboratory for Advanced Metals and MaterialsUniversity of Science and Technology BeijingBeijing100083China Centre for Catalysis and Clean Energy Gold Coast CampusGriffith UniversityGold CoastQLD4222Australia

The synthesis of a perpendicular growth structure of MoS_(2)nanosheets on graphene for efficient sodium storage is challenging yet ideal due to the benefits of open ion diffusion channels and high electronic *** this study,we have successfully fabricated a novel structure of vertical MoS_(2)nanosheets on graphene,with ZnS nanoparticles serving as bonding points(MoS_(2)/ZnS/G),through a facile hydrothermal *** the synthesis process,Zn^(2+)not only acts as a landing site for the vertical growth of MoS_(2)nanosheets but also triggers the formation of a defect-rich structure in the final *** unique architecture of MoS_(2)/ZnS/G effectively combines the advantages of a vertically aligned geometry and a defectrich structure for energy *** resulting structure displays shortened transport paths for electrons/ions,enhanced conductivity,improved structural integrity,and an increased number of active sites for promising electrochemical *** expected,when used as anode for sodium-ion batteries,the as-synthesize d MoS_(2)/ZnS/G exhibits excellent rate capability(high capacity of 298 mAh·g^(-1)at 5 A·g^(-1))and good cycling stability(a capacity decay of 0.056%per cycle after 500 cycles at 1 A·g^(-1)).According to the kinetic investigations,the electrochemical process of the MoS_(2)/ZnS/G sample is primarily governe d by a pseudocapacitive behavior,which enhances the charge/discharge kinetics and allows the MoS_(2)/ZnS/G structure to remain intact during cycling.

关键词： MoS_(2) Perpendicular growth Graphene Sodium storage Electrochemical performance

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Generic Modeling and Control Framework for Power Systems Dominated by Power Converters Connected Through a Passive Transmission and Distribution Grid

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 292-301页

作者： qing-chang Zhong Marcio Stefanello Department of Electrical and Computer Engineering Illinois Institute of TechnologyChicagoIL 60616USA Syndem LLC USA.M.Stefanello is with the Fundacao Universidade Federal do Pampa at AlegreteRS97546-550Brazil

In this paper,a compact mathematical model having an elegant structure,together with a generic control framework,are proposed for generic power systems dominated by power converters that are interconnected through a passive transmission and distribution(T&D)grid,by adopting the port-Hamiltonian(pH)systems theory and the fundamental circuit *** models of generic T&D lines are developed and then the model of a generic T&D grid is *** the proposed control framework,the controlled converters are proven to be passive and Input-to-State Stable(ISS).The compact mathematical model is scalable and can be applied to power systems with multiple power electronic converters with generic passive controllers,passive local loads,and different types of passive T&D lines connected in a meshed configuration without self-loops,so it is very ***,the resulting power system is proven to be ISS as *** analysis is carried out without assumptions on constant frequency/voltage,constant loads,and/or lossless networks,except the need of passivity for all parts involved,and without using the Clarke/Park transformations or the graph *** simplify the presentation,three-phase balanced systems are adopted but the results can be easily adapted for single-phase or unbalanced three-phase systems.

关键词： Input-to-State Stable(ISS) passivity,portHamiltonian(pH)systems Power electronic converters dominated power systems Synchronized and Democratized(SYNDEM)grid architecture

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Neural progenitor cells derived from fibroblasts induced by small molecule compounds under hypoxia for treatment of Parkinson’s disease in rats

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Neural Regeneration Research 2023年第5期18卷 1090-1098页

作者： Yu Guo Yuan-Yuan Wang Ting-Ting Sun Jia-Jia Xu Pan Yang Cai-Yun Ma Wei-Jun Guan Chun-Jing Wang Gao-Feng liu chang-qing liu School of Laboratory Medicine School of Life SciencesBengbu Medical CollegeBengbuAnhui ProvinceChina National Germplasm Resource Center for Domestic Animals Institute of Animal ScienceChinese Academy of Agricultural ScienceBeijingChina Department of Neuroscience University of Connecticut Health CenterFarmingtonCTUSA

Neural progenitor cells(NPCs) capable of self-renewal and differentiation into neural cell lineages offer broad prospects for cell therapy for neurodegenerative diseases. However, cell therapy based on NPC transplantation is limited by the inability to acquire sufficient quantities of NPCs. Previous studies have found that a chemical cocktail of valproic acid, CHIR99021, and Repsox(VCR) promotes mouse fibroblasts to differentiate into NPCs under hypoxic conditions. Therefore, we used VCR(0.5 mM valproic acid, 3 μM CHIR99021, and 1 μM Repsox) to induce the reprogramming of rat embryonic fibroblasts into NPCs under a hypoxic condition(5%). These NPCs exhibited typical neurosphere-like structures that can express NPC markers, such as Nestin, SRY-box transcription factor 2, and paired box 6(Pax6), and could also differentiate into multiple types of functional neurons and astrocytes in vitro. They had similar gene expression profiles to those of rat brain-derived neural stem cells. Subsequently, the chemically-induced NPCs(ciNPCs) were stereotactically transplanted into the substantia nigra of 6-hydroxydopamine-lesioned parkinsonian rats. We found that the ciNPCs exhibited long-term survival, migrated long distances, and differentiated into multiple types of functional neurons and glial cells in vivo. Moreover, the parkinsonian behavioral defects of the parkinsonian model rats grafted with ciNPCs showed remarkable functional recovery. These findings suggest that rat fibroblasts can be directly transformed into NPCs using a chemical cocktail of VCR without introducing exogenous factors, which may be an attractive donor material for transplantation therapy for Parkinson’s disease.

关键词： cell reprogramming cell transplantation hypoxia neural progenitor cells neurological function Parkinson’s disease small molecule compounds substantia nigra

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Wide‑field swept‑source OCT angiography of the periarterial capillary‑free zone before and after anti‑VEGF therapy for branch retinal vein occlusion

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Eye and Vision 2024年第2期10卷 31-40页

作者： Wenyi Tang Wei liu Jingli Guo Lili Zhang Gezhi Xu Keyan Wang qing chang Department of Ophthalmology Eye and ENT Hospital of Fudan University83 Fenyang RoadShanghai 200031China Shanghai Key Laboratory of Visual Impairment and Restoration Fudan UniversityShanghaiChina NHC Key Laboratory of Myopia(Fudan University) Laboratory of MyopiaChinese Academy of Medical SciencesShanghaiChina

Background:The aim of the study was to investigate the changes in the periarterial capillary-free zone(paCFZ)after anti-vascular endothelial growth factor(VEGF)therapy in patients with branch retinal vein occlusion(BRVO)by widefield swept-source optical coherence tomography angiography(SS-OCTA)and assess their associations with clinical ***:In this retrospective observational study of 54 treatment-naive BRVO patients with macular edema,we reviewed the findings of 12×12 mm^(2)SS-OCTA at baseline,3,6,and 12 months after intravitreal ranibizumab *** paCFZ and major retinal artery areas were measured on SS-OCTA *** paCFZ area to artery area(P/A)ratio was ***:The paCFZ areas and P/A ratios of first-and second-order arteries were significantly greater in BRVO eyes than in contralateral eyes(all P<0.01),but there were no differences in the first-and second-order artery areas(P=0.20 and 0.25,respectively).The paCFZ areas and P/A ratios decreased significantly at 3,6,and 12 months after anti-VEGF therapy(all P<0.01).The baseline P/A ratio was significantly correlated with the baseline best-corrected visual acuity(BCVA),central retinal thickness,and their improvements at 3,6,and 12 months(all P<0.05).Baseline BCVA and P/A ratios of first-and second-order arteries were independently associated with the final BCVA in multivariate linear ***:Wide-field SS-OCTA shows that anti-VEGF therapy can lead to a significant improvement in the paCFZ parameters in *** baseline P/A ratios on SS-OCTA tend to predict better visual outcomes at 12 months after anti-VEGF therapy.

关键词： Swept-source optical coherence tomography angiography Branch retinal vein occlusion Periarterial capillary free zone Anti-VEGF treatment Prognosis

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STUDIES ON THE REACTION OF ORGANOTELLURONIUM SALTS

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Chinese Chemical Letters 1991年第1期2卷 51-54页

作者： Qi ZHONG Yu Long CHEHG Jian Guo SHAO chang qing liu Chemistry Department Yangzhou Teachers CollegeYangzhou225002

The structural studies of the telluronium saltrformation between dibutyl telluride and secondary (?)-bromo compounds and the use of the obtai- ned salts for the olefination of carbonyl compounds were reported.

关键词： CHC CN OH CIC STUDIES ON THE REACTION OF ORGANOTELLURONIUM SALTS OCH

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Research on the Icing Diagnosis ofWind Turbine Blades Based on FS–XGBoost–EWMA

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Energy Engineering 2024年第7期121卷 1739-1758页

作者： Jicai Guo Xiaowen Song chang liu Yanfeng Zhang Shijie Guo JianxinWu chang Cai qing’an Li College of Mechanical Engineering Inner Mongolia University of TechnologyHohhot010051China Inner Mongolia Key Laboratory of Special Service Intelligent Robotics Hohhot010051China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing100190China

In winter,wind turbines are susceptible to blade icing,which results in a series of energy losses and safe operation ***,blade icing detection has become a top *** methods primarily rely on sensor monitoring,which is expensive and has limited ***-driven blade icing detection methods have become feasible with the development of artificial ***,the data-driven method is plagued by limited training samples and icing samples;therefore,this paper proposes an icing warning strategy based on the combination of feature selection(FS),eXtreme Gradient Boosting(XGBoost)algorithm,and exponentially weighted moving average(EWMA)*** the training phase,FS is performed using correlation analysis to eliminate redundant features,and the XGBoost algorithm is applied to learn the hidden effective information in supervisory control and data acquisition analysis(SCADA)data to build a normal behavior *** the online monitoring phase,an EWMA analysis is introduced to monitor the abnormal changes in features.A blade icing warning is issued when themonitored features continuously exceed the control limit,and the ambient temperature is below 0℃.This study uses data fromthree icing-affected wind turbines and one normally operating wind turbine for *** experimental results reveal that the strategy can promptly predict the icing trend among wind turbines and stably monitor the normally operating wind turbines.

关键词： Wind turbine blade icing feature selection XGBoost EWMA

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Thickening progression mechanism of silica fume-oil well cement composite system at high temperatures

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Petroleum Science 2024年第4期21卷 2793-2805页

作者： Hang Zhang Miao-Miao Hu Peng-Peng Li Guo-qing liu qing-Lu chang Jie Cao Ming liu Wen-Hua Xu Xiu-Jian Xia Jin-Tang Guo School of Chemical Engineering and Technology Tianjin University Zhejiang Institute of Tianjin University Haihe Laboratory of Sustainable Chemical Transformations CNPC Engineering Technology R&D Company Limited

This work studied the thickening progression mechanism of the silica fume-oil well cement composite system at high temperatures(110-180.C) in order to provide a theoretical guidance for the rational application of silica fume in the cementing engineering. Results showed that silica fume seldom affected the thickening progression of oil well cement slurry at 110-120.C, but when temperature reached above130.C, it would aggravate the bulging degree of thickening curves and significantly extend the thickening time, meanwhile causing the abnormal “temperature-based thickening time reversal” and“dosage-based thickening time reversal” phenomena in the range of 130-160.C and 170-180.C respectively. At 130-160.C, the thickening time of oil well cement slurry was mainly associated with the generation rate of calcium hydroxide(CH) crystal. The introduced silica fume would be attracted to the cement minerals' surface that were hydrating to produce CH and agglomerate together to form an“adsorptive barrier” to hinder further hydration of the inner cement minerals. This “adsorptive barrier”effect strengthened with the rising temperature which extended the thickening time and caused the occurrence of the “temperature-based thickening time reversal” phenomenon. At 170-180.C, the pozzolanic activity of silica fume significantly enhanced and considerable amount of C-S-H was generated, thus the “temperature-based thickening time reversal” vanished and the “dosage-based thickening time reversal” was presented.

关键词： Silica fume Oil well cement Thickening time reversal Pozzolanic reaction Adsorptive barrier CH and C−S−H

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