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On the CR poincaré–Lelong Equation, Yamabe Steady Solitons and Structures of Complete Noncompact Sasakian Manifolds

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Acta Mathematica Sinica,English Series 2018年第8期34卷 1313-1344页

作者： Der Chen chang Shu Cheng chang Ying Bo HAN Chien lin Department of Mathematics and Statistics Georgetown University Washington D. C. 20057 USA Graduate Institute of Applied Science and Engineering Fu Jen Catholic University Taipei 242 Taiwan China Yau Mathematical Sciences Center Tsinghua University Beijing 100084 P. R. China School of Mathematics and Statistics Xinyang Normal University Xinyang 464000 P. R. China Department of Mathematics National Tsing Hua University Hsinchu 30013 Taiwan China

In this paper, we solve the so-called CR poincare-Lelong equation by solving the CR poisson equation on a complete noncompact CR （2n ＋ 1）-manifold with nonegative pseudohermitian bisectional curvature tensors and vanishing torsion which is an odd dimensional counterpart of Kahler geometry. With applications of this solution plus the CR Liouvelle property, we study the structures of complete noncompact Sasakian manifolds and CR Yamabe steady solitons.

关键词： CR poisson equation CR poincare-Lelong equation CR Yamabe solitons

Realizing the excellent oxidation resistance of an environmental barrier coating through aluminum surface modification

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Journal of Advanced Ceramics 2024年第7期13卷 976-986页

作者： lin Dong Wen-Qi Yang lin Chen Guan-Jun Yang chang-Jiu Li State Key Laboratory for Mechanical Behavior of Materials School of Materials Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China Xi’an Aerospace Engine Company Limited in China Aerospace Science and Technology Corporation Xi’an 710065China

The lifetime of Si-based environmental barrier coatings(EBCs)is constrained by thermally grown SiO_(2)oxidelayer(SiO_(2)-TGO),which can cause premature cracking and *** address this issue,a new approach for surfacemodification using aluminum is *** oxidation performance was examined in a 50 vol%H_(2)O-50 vol%O_(2)environment at 1350℃for up to 300 *** results indicate that a dense ytterbium aluminum garnet(YbAG)layer wasformed after modification,decreasing the porosity by 80%.Due to the elimination of fast diffusion channels and the lowoxygen permeability of YbAG,aluminum modification significantly reduced the growth rate of SiO_(2)-TGO by nearly twoorders of ***,its thickness decreased by more than 70%after 300 h of exposure.A diffusioncontrolled oxidation mechanism indicates that the modified dense surface is equivalent to an initial SiO_(2)layer with a specificthickness,causing a shift in the oxidation time and increasing the oxidation *** research provides valuableinsights for designing Si-based EBC with improved lifetimes.

关键词： environmental barrier coating(EBC) oxidation modification diffusion cracking

Recent progress in friction stir welding tools used for steels

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Journal of Iron and Steel Research International 2018年第5期25卷 477-486页

作者： Lei Cui Chao Zhang Yong-chang Liu Xiu-guo Liu Dong-po Wang Hui-jun Li Tianjin Key Laboratory of Advanced Joining Technology School of Materials Science and Engineering Tianjin University Tianjin 300354 China State Key Lab of Hydraulic Engineering Simulation andSafety School of Materials Science and Engineering TianjinUniversity Tianjin 300354 China Faculty of Engineering and Information Sciences Universityof Wollongong Wollongong 2522 NSW Australia

Friction stir welding （FSW） technology is being increasingly attractive in welding steels on account of the high-quality weld formation and excellent weld properties. The feasibility of FSW of steels has been convinced for nearly 20 years. However, the application progress for FSW of steels is slower than that of aluminum alloys owing to the high cost and poor usability of tools. The FSW tools are called as the heart of FSW process which is critical for welding quality control and the weld microstructure and properties. The recent progresses in research and development of FSW tools for welding steels have been reviewed. Material selections, geometry parameters, wear behavior and use life of the tools are summarized from the available literatures.

关键词： Friction stir welding Steel FSW process Tool material Tool design Tool wear behavior

Aldo-keto reductase family member C3(AKR1C3)promotes hepatocellular carcinoma cell growth by producing prostaglandin F2α

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Oncology Research 2024年第1期32卷 163-174页

作者： KUO-SHYANG JENG po-YU CHENG YUEH-HSIEN lin po-CHUN LIU PING-HUI TSENG YU-CHAO WANG CHIUNG-FANG chang CHUEN-MIIN LEU Division of General Surgery Far Eastern Memorial HospitalNew Taipei City22060Taiwan Institute of Microbiology and Immunology National Yang Ming Chiao Tung UniversityTaipei City11221Taiwan Institute of Biochemistry and Molecular Biology National Yang Ming Chiao Tung UniversityTaipei City11221Taiwan Institute of Biomedical Informatics National Yang Ming Chiao Tung UniversityTaipei City11221Taiwan Department of Medical Research Far Eastern Memorial HospitalNew Taipei City22060Taiwan

Hepatocellular carcinoma(HCC)is a leading cause of death *** therapies are effective for HCC patients with early disease,but many patients suffer recurrence after surgery and have a poor response to ***,new therapeutic targets are *** analyzed gene expression profiles between HCC tissues and normal adjacent tissues from public databases and found that the expression of genes involved in lipid metabolism was significantly *** analysis showed that AKR1C3 was upregulated in tumors,and high AKR1C3 expression was associated with a poorer prognosis in HCC *** vitro,assays demonstrated that the knockdown of AKR1C3 or the addition of the AKR1C3 inhibitor indomethacin suppressed the growth and colony formation of HCC cell *** of AKR1C3 in Huh7 cells reduced tumor growth in *** explore the mechanism,we performed pathway enrichment analysis,and the results linked the expression of AKR1C3 with prostaglandin F2 alpha(PGF2a)downstream target *** of AKR1C3 activity reduced the production of PGF2a,and supplementation with PGF2a restored the growth of indomethacin-treated Huh7 *** of the PGF receptor(PTGFR)and treatment with a PTGFR inhibitor significantly reduced HCC *** showed that indomethacin potentiated the sensitivity of Huh7 cells to *** summary,our results indicate that AKR1C3 upregulation may promote HCC growth by promoting the production of PGF2α,and suppression of PTGFR limited HCC ***,targeting the AKR1C3-PGF2a-PTGFR axis may be a new strategy for the treatment of HCC.

关键词： Hepatocellular carcinoma Aldo-keto reductase family member C3 Prostaglandin F2 alpha Prostaglandin F receptor

Variations in the disintegration rate of physical crusts induced by artificial rainfall in different alcohol concentrations

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International Soil and Water Conservation Research 2022年第4期10卷 565-573页

作者： lin Chen chang Yang Qingwei Zhang Jian Wang Institute of Soil and Water Conservation Northwest A&F UniversityYangling712100ShaanxiChina College of Natural Resources and Environment Northwest A&F UniversityYangling712100ShaanxiChina

Disintegration is closely correlated with geological disasters and soil ***,quantitative studies on the disintegration processes of physical crust controlling the soil surface erosion are ***,we disintegration process in structural and sedimentary crusts induced by artificial rainfall on a typical cropland soil from the Loess Plateau,*** physical crusts were immersed for 200 s at different alcohol concentrations applied for delaying disintegration process to obtain disintegration rate(DR).The content of organic matter and the sand percentage in the structural and sedimentary crusts decreased with increasing rainfall duration,while the bulk density,silt and clay percentages *** initial DR values ranged from0.01 to 1.82 in structural crusts and from0.01 to 1.47 in sedimentary crusts under different alcohol *** decreased by[86.5%,91.3%]in structural crusts and by[86.3%,88.2%]in sedimentary crusts during the whole disintegration *** both structural and sedimentary crust,the DR was the lowest when the rainfall lasted for 30 min,and finally stabilized at 0.19 and 0.18,respectively,at the disintegration time of 80 ***,the 50%alcohol concentration slowed the disintegration process most *** structural crust had a lower erosion resistance than the sedimentary crust due to the lower *** results provide a theoretical method for evaluating disintegration process and timely information revealing the erosion resistance mechanism of physical crusts.

关键词： Artificial rainfall Physical crusts Alcohol Disintegration Micro-terrain

Design of piezoelectric energy harvesting devices subjected to broadband random vibrations by applying topology optimization

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Acta Mechanica Sinica 2011年第5期27卷 730-737页

作者： Zhe-Qi lin Hae chang Gea Shu-Tian Liu Department of Engineering Mechanics Dalian University of Technology116024 Dalian China Department of Mechanical and Aerospace Engineering Rutgers The State University of New JerseyPiscataway NJ 08854 USA

Converting ambient vibration energy into electrical energy by using piezoelectric energy harvester has attracted a lot of interest in the past few *** this paper,a topology optimization based method is applied to simultaneously determine the optimal layout of the piezoelectric energy harvesting devices and the optimal position of the mass *** objective function is to maximize the energy harvesting performance over a range of vibration *** excitation method （PEM） is adopted to analyze structural stationary random responses,and sensitivity analysis is then performed by using the adjoint *** examples are presented to demonstrate the validity of the proposed approach.

关键词： Topology optimization · Energy harvesting · Piezoelectric material ··

A Novel Heat-resisting Surfactant for the Modification of Alumina Nanoparticles

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Chinese Chemical Letters 2003年第1期14卷 104-107页

作者： Yu Fen chang Yuan Bo lin 等 SchoolofChemicalEngineering DalianUniversityofTechnologyDalian116012 MaterialScienceandTechnologyDepartment TsinghuaUniversityBeijing100084

An easy preparation of controlled alumina nanoparticles by the solution precipitate method has been carried out using dendrimer as surfactant. The effects of the amount and size of surfactant on morphological control... 详细信息

关键词： Alumina nanoparticles dendrimer surfactant.

Regulating metalloimmunology with nanomedicine for cancer therapy

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Nano Research 2023年第12期16卷 13164-13181页

作者： Saibo Ma lin Chen Muhammad Hamza Jing chang Motao Zhu College of Marine Life Science Ocean University of ChinaQingdao 266003China CAS Key Laboratory for Biomedical Effects of Nanomaterials&Nanosafety CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China Laboratory for Marine Drugs and Bioproducts Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266235China University of Chinese Academy of Sciences Beijing 100049China

Metals are essential components of both micronutrients and macronutrients in living organisms and are involved in a variety of immune processes in the forms of free ions or protein-coupled complexes(metalloproteins).Multiple aspects of the immune system,from the structural and functional control of immune-related proteins to the cellular responses to immunotherapy,could be affected by ***,the employment of metal for the regulation of immunity,termed as metalloimmunology,is gaining interest as a prevalent and efficacious approach to combating ***,the manipulation of metalloimmunology using traditional drugs presents several challenges,including limited bioavailability,adverse effects,and a lack of targeting *** review provides an overview of the latest findings in metal and metal-regulatory therapeutic agents for the treatment of *** trace metal elements,such as iron,zinc,copper,manganese,magnesium,and calcium,as well as heavy metal drugs and their mechanisms of action,will be discussed with a particular focus on their roles in regulating the tumor-immune *** latest nanotechnology employed in the administration of metal-regulatory drugs and the design concepts for tailored therapeutic interventions will be *** concepts and information offer promising clinical possibilities of modulating cancer immunology by targeting metal metabolism.

关键词： metalloimmunology metal metabolism cancer immunotherapy nano-enabled delivery system cGAS-STING pathway ferroptosis and cuprotosis

Assessment of Habitat Suitability in the Upper Reaches of the Min River in China

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Journal of Mountain Science 2015年第3期12卷 737-746页

作者： GUO Ya-lin WANG Qing YAN Wei-po ZHOU Qin SHI Min-qiu School of Environment and Resource Southwest University of Science and Technology

HabRat richness influences and even determines biological diversity. Plant habitat suitability assessment can provide technical guidance and information support for ecological restoration. Thirteen factors in three categories of terrain, meteorology and soil were chosen to build a habitat suitability assessment index framework in the Upper Reaches of the Min River, based on the local natural environment and the actual influencing factors of vegetative growth. Combined with the Analytic Hierarchy Process （AHP） and entropy method, which were used to calculate weights of indexes, habitat suitability was studied by using a multi-objective linear weighting model and geographic information systems （GIS） spatial analysis techniques. The assessment results are as follows： Altitude, soil stability, aspect and slope have more important effects on plant habitat suitability in the Upper Reaches of the Min River, and their weights are o.311, 0.260, o.198 and o.125, respectively. Suitable and sub-suitable habitats cover 4431.8o km2 and 6171.12 km2, respectively; most of which are distributed along both sides of rivers and have higher suitability. Unsuitable habitats cover the largest area （6679.76 km2）, accounting for 29.83% of the whole area; and the worst unsuitable habitats are 5107.23 km2 （22.81%）; they account for more than half of the study area. These results indicate that the plant habitat in the Upper Reaches of the Min River is poor and ecological restoration is both urgent and difficult. Therefore, based on the principle of taking measures suitable to the habitat in ecological restoration projects, ecological and engineering measures should be combined to have better effects, while increasing the strength of ecological protection.

关键词： Habitat suitability Analytic hierarchyprocess (AHP) Entropy method Spatial analysis Min River China