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Nanodiamond/Ti_(3)C_(2) MXene-coated quartz crystal microbalance humidity sensor with high sensitivity and high quality factor

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Rare Metals 2024年第6期43卷 2719-2729页

作者： Yao Yao Qiao chen Yan-Qi Li Xian-He Huang Wei-Wei Ling Zhe-MiaoXie Jia-QiWang chang-ming chen College of Communication Engineering Chengdu University of Information TechnologyChengdu 610225China School of Automation Chongqing University of Posts and TelecommunicationsChongqing 400065China School of Automation Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Advanced Micro-/Nano-Devices Lab Department of Systems Design EngineeringUniversity of WaterlooWaterlooON N2L 3GlCanada

To address the challenge of achieving both high sensitivity and a high quality factor in quartz crystal microbalance(QCM)humidity sensors,a nanodiamond(ND)/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was *** material characteristics of ND,Ti_(3)C_(2)MXene,and ND/Ti_(3)C_(2)MXene composite were analyzed by transmission electron microscopy(TEM)and Fourier transform infrared(FTIR)*** experimental results demonstrated that the hydrophilic ND nanoparticles coated on Ti_(3)C_(2) MXene nanosheet prevented the self-stacking of Ti_(3)C_(2)MXene and enhanced the sensitivity of Ti_(3)C_(2) MXene-based QCM humidity ***,the high mechanical modulus of Ti_(3)C_(2) MXene material helped ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor to achieve a high quality factor(>20,000).ND/Ti_(3)C_(2)MXene compositecoated QCM humidity sensor exhibited a sensitivity of 82.45 Hz/%RH,a humidity hysteresis of 1.1%RH,fast response/recovery times,acceptable repeatability,and good stability from 11.3%RH to 97.3%*** response mechanism of ND/Ti_(3)C_(2) MXene composite-coated QCM humidity sensor was analyzed in combination with a bi-exponential kinetic adsorption ***,the potential application of ND/Ti_(3)C_(2)MXene composite-coated QCM humidity sensor was demonstrated through its frequency response to wooden blocks with different moisture contents.

关键词： Humidity sensor Quartz crystal microbalance Nanodiamond Ti_(3)C_(2)MXene High quality factor

Study on the stannous halides promoted addition of 1,1,1-trichloro-2,2,2-trifluoroethane to aldehydes and the chemical transformation thereof

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Chinese Journal of Chemistry 1994年第2期12卷 183-189页

作者： HU, chang-ming chen, JianShanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China

Promoted by stannous salts, 1,1,1-trichloro-2,2,2-trifluoroethane reacts readily with aliphatic, aromatic, and α, β-unsaturated aldehydes giving the corresponding alcohols bearing a CF3CCl2-moiety in good to excelle... 详细信息

关键词： 1,1,1-Trichloro-2,2,2-trifluoroethane aldehydes stannous halides addition Jones oxidation ketones.

Tunable wavelength filters using polymer long-period waveguide gratings based on metal-cladding directly defined technique

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Chinese Physics B 2017年第2期26卷 268-273页

作者： Ji-Hou Wang chang-ming chen Yang Zheng Xi-Bin Wang Yun-Ji Yi Xiao-Qiang Sun Fei Wang Da-ming Zhang State Key Laboratory on Integrated Optoelectronics College of Electronic Science and Engineering Jilin University Changchun 130012 China

In this work, long-period waveguide grating-based tunable wavelength filters using organic–inorganic grafting poly（methyl methacrylate）（PMMA） materials are designed and fabricated by metal-cladding directly defined *** thermal stabilities and optical properties of the organic–inorganic grafting PMMA core materials are analyzed. Structures and performance parameters of the waveguide gratings and self-electrode heaters are designed and simulated. The contrast of the filter is about 15 d B and the resonant wavelength can be tuned by different electric powers applied to the metal-cladding self-electrode heaters. The temperature sensitivity is 3.5 nm/℃ and the switching time is about 1 ms. The technique is very suitable for realizing the optoelectronic integrated wavelength-division-multiplexing systems.

关键词： organic–inorganic grafting materials polymer optical waveguide long-period grating filter metalcladding defined technique

Compact 2×2 parabolic multimode interference thermo–optic switches based on fluorinated photopolymer

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Chinese Physics B 2019年第4期28卷 216-223页

作者： Ji-Hou Wang chang-ming chen Ke-Wei Hu Ru cheng Chun-Xue Wang Yun-Ji Yi Xiao-Qiang Sun Fei Wang Zhi-Yong Li Da-ming Zhang State Key Laboratory of Integrated Optoelectronics College of Electronic Science and Engineering Jilin University State Key Laboratory of Integrated Optoelectronics Institute of Electronic Semiconductors Chinese Academy of Sciences

In this work, a dual-side parabolic structural(DSPS) multimode interference(MMI) thermo–optic(TO) waveguide switch is designed and fabricated by using novel low-loss fluorinated photopolymer materials. Comparing with the traditional dual-side linear structural(DSLS) MMI device, the effective length of the MMI coupling region proposed can be effectively reduced by 40%. The thermal stability of the waveguide material is analyzed, and the optical characteristics of the switching chip are simulated. The actual performances of the entire MMI switch are measured with an insertion loss of7 dB, switching power of 15 m W and an extinction ratio of 28 dB. In contrast to the traditional MMI optical switch, the new type of parabolic structural MMI TO waveguide switch exhibits lower power consumption and larger extinction ratio. The compact fluorinated polymer MMI TO switches are suitable well for realizing miniaturization, high-properties, and lower cost of photonic integrated circuits.

关键词： fluorinated photopolymer materials parabolic structural MMI thermo–optic waveguide switches

STUDY ON Cp_2TiCl_2/Fe-INITIATED ADDITION OF 2-HALOTETRAFLUOROETHYL IODIDES TO ALKYNES AND ALKENES

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Chinese Chemical Letters 1993年第10期4卷 853-854页

作者： chang ming HU Jian chen Yao Ling QIU Shanghai Institute of Organic Chemistry,Academia Sinica,345 Lingling Lu,Shanghai 200032.

Initiated by CP_2TiCl_2/Fe redox system,2-halotetrafluoroethyl iodides readily reacted with alkynes or alkenes to give 1:1 adducts in good to excellent yields.

关键词： Fe STUDY ON Cp2TiCl2/Fe-INITIATED ADDITION OF 2-HALOTETRAFLUOROETHYL IODIDES TO ALKYNES AND ALKENES Hg

TCM therapy for patients with positive antibody response to SARS-CoV-2

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Drug Combination Therapy 2023年第2期5卷 40-43页

作者： chang-ming chen Wei-Jing Wang Man Wang Li Hai Xiao-Nan Wang Preventive Medicine Department Beijing Fengtai District Hospital of Chinese MedcineBeijing 100076China

Objective:This study aimed to observe the efficacy and safety of traditional Chinese medicine therapy in patients with positive antibody responses to severe acute respiratory syndrome coronavirus ***:A retrospective observation was conducted on 25 patients with positive antibody responses but negative nucleic acid testing results who received Anshouxinshen *** changes in symptoms,infective indicators,and safety were ***:Following treatment,the positive IgM responses of 18 patients became negative within one week,with an average time for antibody to become negative being 2 *** the seven patients with positive IgG responses,six became IgG-negative with an average time for antibody to become negative being 6.8 *** symptoms of anxiety,insomnia,cough,fever,fatigue,and other symptoms improved 100%for all *** treatment,the lymphocyte count and lymphocyte ratio of patients significantly *** adverse reactions to Anshouxinshen therapy were ***:Anshouxinshen therapy is an effective treatment for patients with positive antibody responses to syndrome coronavirus 2,safely improving their immune *** traditional Chinese medicine intervention can reduce the incidence of coronavirus disease 2019 and improve its cure rate,thereby promoting the prevention and control of coronavirus disease 2019.

关键词： COVID-19 antibody Chinese medicine Anshouxinshen therapy

All polymer asymmetric Mach-Zehnder interferometer waveguide sensor by imprinting bonding and laser polishing

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Chinese Physics B 2017年第12期26卷 332-338页

作者：刘豫孙月衣云骥田亮曹悦陈长鸣孙小强张大明 State Key Laboratory on Integrated Optoelectronics College of Electronic Science and Engineering Jilin University Changchun 130012 China

We present an all polymer asymmetric Mach-Zehnder interferometer （AMZI） waveguide sensor based on imprinting bonding and laser polishing method. The fabrication methods are compatible with high accuracy waveguide sensing structure. The rectangle waveguide structure of this sensor has three sensing surfaces contacting the test media, and its sensing accuracy can be increased 5 times compared with that of one surface sensing structure. An AMZI device structure is designed. The single mode condition, the length of the sensing arm, and the length deviation between the sensing arm and the reference arm are optimized. The length deviation is optimized to be 19.8 μm in a refractive index range between 1.470 and 1.545. We fabricate the AMZI waveguide by lithography and wet etching method. The imprinting bonding and laser polishing method is proposed and investigated. The insertion loss is between-80.36 dB and-10.63 dB. The average and linear sensitivity are 768.1 dB/RIU and 548.95 dB/RIU, respectively. And the average and linear detection resolution of the sensor are 1.3010-6 RIU （RIU：refractive index unit） and 1.8210-5 RIU, respectively. This sensor has a fast and cost-effective fabrication process which can be used in the cases of requiring portability and disposability.

关键词： integrated optics devices polymer waveguides sensors microstructure fabrication

Needle knife in the treatment of primary dysmenorrhea: a systematic review and meta-analysis

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TMR Integrative Medicine 2022年第22期6卷 1-6页

作者： Ji-Ju Wang Ke Liu Dong-Mei Wang Tian-Min Zhang Long-Feng Hu chang-ming chen Department of Obstetrics and Gynecology Beijing Fengtai District Hospital of Chinese Medicine Beijing 100071China Teaching and Research Office of Acupotomology Hubei University of Chinese Medicine Wuhan 430065China

Objective: The aim of this meta-analysis was to examine the effectiveness and safety ofneedle knives for primary dysmenorrhea. Methods: We searched the electronicdatabases from their inception to May 25, 2022, comprising Cochrane Library, PubMed,Embase, SinoMed, CNKI, VIP and Wanfang databases. Randomized controlled trials(RCTs) investigating the effectiveness of needle knives for people with primarydysmenorrhea were eligible. The risk of bias and the quality of the included literaturewere evaluated. RevMan5.3 software was used for this study. Results: Five articles with313 participants were involved in the review. The cure rate (2.82 (2.01, 3.95), I^(2) = 25%)and total effective rate (1.32 (1.10, 1.57), I^(2) = 65%) of the experimental group werehigher than those of the control group. The dysmenorrhea symptom scores (–1.81(–2.61, –1.01), I^(2) = 69%), TCM symptom scores (–4.19 (–6.06, –2.31), I2 = 0%) andadverse reactions (0.16 (0.05, 0.51), I^(2) = 0%) of the experimental group were lowerthan those of the control group. Conclusions: Needle knives may provide advantages inthe treatment of primary dysmenorrhea. RCTs, including the larger sample, multi-center,high-quality and double-blind research, were required to further verify the efficacy ofneedle knives for primary dysmenorrhea.

关键词： needle knife primarydysmenorrhea effectiveness safety meta-analysis

Enhancement of motor functional recovery in thoracic spinal cord injury: voluntary wheel running versus forced treadmill exercise

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Neural Regeneration Research 2025年第3期20卷 836-844页

作者： Do-Hun Lee Dan Cao Younghye Moon chen chen Nai-Kui Liu Xiao-ming Xu Wei Wu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteIndiana University School of MedicineIndianapolisINUSA Department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA Department of Neuroscience Baylor College of MedicineHoustonTXUSA

Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.

关键词： behavioral assessment motor function neural plasticity running wheel exercise spinal cord injury treadmill exercise voluntary exercise