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Chinese Journal of Structural Chemistry 2006年第8期25卷 937-939页

作者： SHI Jing-Min XU Hong-Kun WU chang-Ju liu lian-Dong Department of Chemistry Shandong Normal University Jinan 250014 China

The three-dimensional complex [Cd（μ1,3-SCN）（μ3-pco）]n has been synthesized with μ1,3-SCN^- and pco as mixed bridged ligands. The crystal belongs to monoclinic, space group P21/n with a = 10.3777（16）, b = 6.2592（9）, c = 13.150（2） A, β= 97.317（2）°, V= 847.2（2） A^3, Z= 4, C6H3CdN3O3S, Mr = 309.575, Dc = 2.427 g/cm^3, F（000） = 592 and μ = 2.804 mm^-1. The structure was refined to R = 0.0255 and wR = 0.0550 for 1712 observed reflections （1 〉 2σ（I））. In the crystal the Cd（Ⅱ） ions are coordinated by μ1,3-SCN^- and μ3-pco bridge ligands to form a three-dimensional structure.

关键词： synthesis crystal structure cadmium(Ⅱ) complex thiocyanate aromatic N-oxide

Syntheses and Crystal Structures of Two Coordination Polymers with Aromatic Dioxide as Bridge Ligands

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Chinese Journal of Structural Chemistry 2007年第2期26卷 214-218页

作者： SHI Jing-Min XU Hai-Yan ZHANG Feng-Xia WU chang-Ju liu lian-Dong Department of Chemistry Shandong Normal University Jinan 250014 China

Two coordination polymers, namely, two-dimensional complex 1 {[Cu（μ- L）1.5（ClO4）2（H2O）].（H2O）0.5]n （L = pyrazine-1,4-dioxide） and one-dimensional complex 2 [Co（μ-L）Br2（H2O）2]n, have been synthesized with pyrazine-1,4-dioxide as bridging ligands, and their crystal structures were determined by X-ray crystallography. Crystal data for complex 1： monoclinic system, space group C2/c, with a = 23.310（3）, b = 12.2338（17）, c = 10.6075（15） A, β= 110.487（2）°, V = 2833.6（7） A3, Z = 8, C6H9C12CuN3O12.5, Mr = 457.60, Dc = 2.145 g/cm^3, F（000） = 1832 and μ = 1.998 mm^-1; and those for 2： monoclinic system, space group C2/c, with a = 11.012（3）, b = 7.483（2）, c = 11.451（3） A, β = 101.654（4）°, V = 924.2（4） A3, Z = 4, C4HsBr2CoN2O4, Mr = 366.87, Dc = 2.637 g/cm^3, F（000） = 700 and μ = 10.487 mm^-1. 1 shows a two-dimensional sheet structure on the ac plane through the coordination of μ-L bridging ligands with Cu（Ⅱ） ions, while 2 displays a zigzag one-dimensional chain along the c axis via the coordination of μ-L bridging ligand with Co（Ⅱ） ions. Hydrogen bonds in 1 and 2 make the sheets （or chains） connect each other to form a three-dimensional structure.

关键词： Aromatic Dioxide coordination polymers Hydrogen bonds

Efficacy of Surgical Therapy for Carotid Body Tumors

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Chinese Medical Sciences Journal 2011年第4期26卷 241-245页

作者： Li-shan lian chang-wei liu Heng Guan Yue-hong Zheng Xing-ming Chen Yong-jun Li Department of Vascular Surgery Peking Union Medical College Hospital ChineseAcademy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 China

Objective To evaluate the efficacy of surgical therapy for carotid body tumors. Methods A retrospective analysis was conducted, covering the diagnosis, surgical procedure, postoperative complications, and prognosis of 120 cases of carotid body tumors in Peking Union Medical College Hospital from 1949 to May, 2011. Results Surgical excision was successfully performed in 111 cases with 117 tumors. In all those cases, 50 underwent simple tumor resection, 42 underwent resection of tumors and ligation of the external carotid arteries, 7 underwent co-resection of tumors and common carotid arteries, internal carotid arteries, as well as external arteries without vascular reconstruction, and the other 12 cases experienced tumor resection and vascular reconstruction as internal carotid arteries were involved. After operation, 3 cases developed cerebral infarction, 30 cases showed cranial nerve palsy, including 15 cases of hypoglossal nerve damage, 10 cases of vagus paralysis, and 5 cases of Horner's syndrome. Conclusion It is essential to make a proper surgical strategy, which can reduce postoperative com- plications.

关键词： carotid body tumor surgical therapy postoperative complication

Emerging materials and transistors for integrated circuits

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National Science Review 2024年第3期11卷 7-8页

作者： Ming liu lian-Mao Peng Lab of Nanofabrication and Novel Device Integration Institute of Microelectronics Chinese Academy of Sciences Key Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics School of Electronics Peking University

The device technology for integrated circuits(ICs) has received a great deal of attention in the past decade since the mainstream silicon-based complementary metal-oxide-semiconductor(CMOS) field-effect transistor(FET) for modern ICs had been encountering development bottlenecks due to the combination of power constraints, physics, cost and fabrication processes.

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A vibration isolator with a controllable quasi-zero stiffness region based on nonlinear force design

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Applied Mathematics and Mechanics(English Edition) 2024年第8期45卷 1279-1294页

作者： Xinyu lian Bing liu Huaxia DENG Xinglong GONG CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern MechanicsUniversity of Science and Technology of ChinaHefei 230027China State Key Laboratory of Nonlinear Mechanics Institute of MechanicsChinese Academy of SciencesBeijing 100190China State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei 230026China

To achieve stability optimization in low-frequency vibration control for precision instruments,this paper presents a quasi-zero stiffness(QZS)vibration isolator with adjustable nonlinear ***,the stress-magnetism coupling model is established through meticulous theoretical *** controllable QZS interval is constructed via parameter design and magnetic control,effectively segregating the high static stiffness bearing section from the QZS vibration isolation ***,a displacement control scheme utilizing a magnetic force is proposed to regulate entry into the QZS working range for the vibration isolation *** results demonstrate that the operation within this QZS region reduces the peak-to-peak acceleration signal by approximately 66.7%compared with the operation outside this region,thereby significantly improving the low frequency performance of the QZS vibration isolator.

关键词： low frequency nonlinear vibration isolator quasi-zero stiffness(QzS)

Recent advances in fabrication and functions of neuromorphic system based on organic field effect transistor

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International Journal of Extreme Manufacturing 2024年第2期6卷 273-295页

作者： Yaqian liu Minrui lian Wei Chen Huipeng Chen School of Physics and Electronic Engineering Zhengzhou University of Light IndustryHenan 450002People’s Republic of China Institute of Optoelectronic Display National&Local United Engineering Lab of Flat Panel Display TechnologyFuzhou UniversityFuzhou 350002People’s Republic of China Joint School of National University of Singapore and Tianjin University International Campus of Tianjin UniversityFuzhou 350207People’s Republic of China Department of Chemistry National University of Singapore3 Science Drive 3Singapore 117543Singapore Department of Physics National University of Singapore3 Science Drive 3Singapore 117543Singapore

The development of various artificial electronics and machines would explosively increase the amount of information and data,which need to be processed via in-situ *** synapse devices can store and process signals in a parallel way,thus improving fault tolerance and decreasing the power consumption of artificial *** organic field effect transistor(OFET)is a promising component for bioinspired neuromorphic systems because it is suitable for large-scale integrated circuits and flexible *** this review,the organic semiconductor materials,structures and fabrication,and different artificial sensory perception systems functions based on neuromorphic OFET devices are ***,a summary and challenges of neuromorphic OFET devices are *** review presents a detailed introduction to the recent progress of neuromorphic OFET devices from semiconductor materials to perception systems,which would serve as a reference for the development of neuromorphic systems in future bioinspired electronics.

关键词： organic field effect transistor neuromorphic systems synaptic transistor sensory perception systems device fabrication

Succinylation modification:a potential therapeutic target in stroke

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Neural Regeneration Research 2024年第4期19卷 781-787页

作者： Jie lian Wenwu liu Qin Hu Xiaohua Zhang Department of Neurosurgery Ren Ji HospitalShanghai Jiao Tong University School of Medicine Department of Diving and Hyperbaric Medicine Naval Medical CenterNaval Medical University

Stroke is a leading cause of mortality and disability *** cell death triggered by the compromised supply of blood oxygen and glucose is one of the major pathophysiology of strokeinduced brain *** mitochondrial energy metabolism is observed minutes after stroke and is closely associated with the progression of ***,a new type of posttranslational modification,known as lysine succinylation,has been recognized to play a significant role in mitochondrial energy metabolism after ***,the role of succinylation modification in cell metabolism after stroke and its regulation are not well *** aimed to review the effects of succinylation on energy metabolism,reactive oxygen species generation,and neuroinflammation,as well as Sirtuin 5 mediated desuccinylation after *** also highlight the potential of targeting succinylation/desuccinylation as a promising strategy for the treatment of *** succinylation level is dynamically regulated by the nonenzymatic or enzymatic transfer of a succinyl group to a protein on lysine residues and the removal of succinyl catalyzed by *** evidence has suggested that succinylation can regulate the metabolic pathway through modulating the activity or stability of metabolic ***,especially Sirtuin 5,are characterized for their desuccinylation activity and have been recognized as a critical regulator of metabolism through desuccinylating numerous metabolic *** between succinylation and desuccinylation has been implicated in the pathophysiology of *** agents that enhance the activity of Sirtuin 5 have been employed to promote desuccinylation and improve mitochondrial metabolism,and neuroprotective effects of these agents have been observed in experimental stroke ***,their therapeutic efficacy in stroke patients should be validated.

关键词： mitochondria metabolism neuroprotection sirtuin 5 stroke succinylation modification

A Novel Multi-Stream Fusion Network for Underwater Image Enhancement

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China Communications 2024年第2期21卷 166-182页

作者： Guijin Tang lian Duan Haitao Zhao Feng liu Jiangsu Key Laboratory of Image Processing and Image Communication Nanjing University of Posts and TelecommunicationsNanjing 210003China Jiangsu Key Laboratory of Wireless Communications Nanjing University of Posts and TelecommunicationsNanjing 210003China

Due to the selective absorption of light and the existence of a large number of floating media in sea water, underwater images often suffer from color casts and detail blurs. It is therefore necessary to perform color correction and detail restoration. However,the existing enhancement algorithms cannot achieve the desired results. In order to solve the above problems, this paper proposes a multi-stream feature fusion network. First, an underwater image is preprocessed to obtain potential information from the illumination stream, color stream and structure stream by histogram equalization with contrast limitation, gamma correction and white balance, respectively. Next, these three streams and the original raw stream are sent to the residual blocks to extract the features. The features will be subsequently fused. It can enhance feature representation in underwater images. In the meantime, a composite loss function including three terms is used to ensure the quality of the enhanced image from the three aspects of color balance, structure preservation and image smoothness. Therefore, the enhanced image is more in line with human visual ***, the effectiveness of the proposed method is verified by comparison experiments with many stateof-the-art underwater image enhancement algorithms. Experimental results show that the proposed method provides superior results over them in terms of MSE,PSNR, SSIM, UIQM and UCIQE, and the enhanced images are more similar to their ground truth images.

关键词： image enhancement multi-stream fusion underwater image

Porous-DeepONet:Learning the Solution Operators of Parametric Reactive Transport Equations in Porous Media

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Engineering 2024年第8期39卷 94-103页

作者： Pan Huang Yifei Leng Cheng lian Honglai liu State Key Laboratory of Chemical Engineering&Shanghai Engineering Research Center of Hierarchical Structure Nanomaterials School of Chemical EngineeringEast China University of Science and TechnologyShanghai 200237China School of Chemistry and Molecular Engineering East China University of Science and TechnologyShanghai 200237China Product Planning and New Auto Technologies Research Institute BYD Auto Industry Company LimitedShenzhen 518118China

Reactive transport equations in porous media are critical in various scientific and engineering disciplines,but solving these equations can be computationally expensive when exploring different scenarios,such as varying porous structures and initial or boundary *** deep operator network(DeepONet)has emerged as a popular deep learning framework for solving parametric partial differential ***,applying the DeepONet to porous media presents significant challenges due to its limited capability to extract representative features from intricate *** address this issue,we propose the Porous-DeepONet,a simple yet highly effective extension of the DeepONet framework that leverages convolutional neural networks(CNNs)to learn the solution operators of parametric reactive transport equations in porous *** incorporating CNNs,we can effectively capture the intricate features of porous media,enabling accurate and efficient learning of the solution *** demonstrate the effectiveness of the Porous-DeepONet in accurately and rapidly learning the solution operators of parametric reactive transport equations with various boundary conditions,multiple phases,and multiphysical fields through five *** approach offers significant computational savings,potentially reducing the computation time by 50–1000 times compared with the finite-element *** work may provide a robust alternative for solving parametric reactive transport equations in porous media,paving the way for exploring complex phenomena in porous media.

关键词： Porous media Reactive transport Solution operator DeepONet Neural network

Prediction of cell-cell communication patierns of dorsal root ganglion cells: single-cell RNA sequencing data analysis

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Neural Regeneration Research 2024年第6期19卷 1367-1374页

作者： Yanna lian Cheng Wu Li liu Xiangyao Li National Health Commission and Chinese Academy of Medical Sciences Key Laboratory of Medical Neurobiology Ministry of Education Frontier Science Center for Brain Research and Brain-Machine Integration School of Brain Science and Brain Medicine Zhejiang University International Institutes of Medicine the Fourth Affiliated Hospital of Zhejiang University School of Medicine Zhejiang University-University of Edinburgh Institute Zhejiang University School of Medicine Zhejiang University 4. Biomedical Sciences College of Medicine and Veterinary Medicine The University of Edinburgh Core Facilities of the School of Medicine Zhejiang University

Dorsal root ganglion neurons transmit peripheral somatic information to the central nervous system, and dorsal root ganglion neuron excitability affects pain perception. Dorsal root ganglion stimulation is a new approach for managing pain sensation. Knowledge of the cell-cell communication among dorsal root ganglion cells may help in the development of new pain and itch management strategies. Here, we used the single-cell RNA-sequencing(scRNA-seq) database to investigate intercellular communication networks among dorsal root ganglion cells. We collected scRNA-seq data from six samples from three studies, yielding data on a total of 17,766 cells. Based on genetic profiles, we identified satellite glial cells, Schwann cells, neurons, vascular endothelial cells, immune cells, fibroblasts, and vascular smooth muscle cells. Further analysis revealed that eight types of dorsal root ganglion neurons mediated proprioceptive, itch, touch, mechanical, heat, and cold sensations. Moreover, we predicted several distinct forms of intercellular communication among dorsal root ganglion cells, including cell-cell contact, secreted signals, extracellular matrix, and neurotransmitter-mediated signals. The data mining predicted that Mrgpra3-positive neurons robustly express the genes encoding the adenosine Adora2b(A2B) receptor and glial cell line-derived neurotrophic factor family receptor alpha 1(GFRα-1). Our immunohistochemistry results confirmed the coexpression of the A2B receptor and GFRα-1. Intrathecal injection of the A2B receptor antagonist PSB-603 effectively prevented histamine-induced scratching behaviour in a dose-dependent manner. Our results demonstrate the involvement of the A2B receptor in the modulation of itch sensation. Furthermore, our findings provide insight into dorsal root ganglion cell-cell communication patterns and mechanisms. Our results should contribute to the development of new strategies for the regulation of dorsal root ganglion excitability.

关键词： cell-cell communications CellChat dorsal root ganglion scRNA-Seq database