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不同宿主来源产气荚膜梭菌生物被膜形成前后药物敏感性分析

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动物医学进展 2025年第1期46卷 38-42页

作者：吴莹邵长军刘文华青岛农业大学动物医学院山东青岛266109 烟台市农科院山东烟台264200

为了检测5株不同宿主来源产气荚膜梭菌形成生物被膜能力及其对抗菌药物的敏感性差异,首先用纸片扩散法药敏试验测定5株不同来源的产气荚膜梭菌对7种抗菌药物的敏感性;筛选高敏药物测定各菌株的最小抑菌浓度(MIC);利用结晶紫染色法检测... 详细信息

为了检测5株不同宿主来源产气荚膜梭菌形成生物被膜能力及其对抗菌药物的敏感性差异,首先用纸片扩散法药敏试验测定5株不同来源的产气荚膜梭菌对7种抗菌药物的敏感性;筛选高敏药物测定各菌株的最小抑菌浓度(MIC);利用结晶紫染色法检测不同来源产气荚膜梭菌生物被膜形成能力和高敏药物对生物被膜的抑制和清除能力。药敏结果显示,5株不同宿主来源产气荚膜梭菌均对氨苄西林高度敏感,对其余6种抗菌药物有不同程度耐药;氨苄西林对不同菌株的MIC值在0.031~2.000μg/mL之间;所有菌株均能生成生物被膜,但生物被膜生成能力有差异;不同菌株在各自4、2、1 MIC下生物被膜的生成受到不同程度抑制,而亚抑菌浓度的氨苄西林能刺激生物被膜的生成,氨苄西林对已经生成的生物被膜不能完全清除。结果表明,不同来源产气荚膜梭菌形成生物被膜前后对药物敏感性不同,可为产气荚膜梭菌的临床用药选择及使用剂量提供一定的参考依据。

关键词：产气荚膜梭菌生物被膜最小抑菌浓度耐药性

Néel Transition and Staggered Magnetization of La_(2-δ)Sr_(δ)CuO_(4)

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Chinese Physics Letters 2000年第12期17卷 905-906页

作者： chang Zhe Institute of High Energy Physics Chinese Academy of SciencesBeijing 100039

The doped anisotropic antiferromagnet,which is believed to describe the elementary properties of the high-temperature superconductors,is studied by making use of Green’s function theory of the t-J *** Néel transition and staggered magnetization dependence on the anisotropic parameter ς and the doping density δ in La_(2-δ)Sr_(δ)CuO_(4) are *** results are found to be in good agreement with experiments on the cuprates.

关键词： anisotropic Transition elementary

A review of the microseismic focal mechanism research

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Science China Earth Sciences 2021年第3期64卷 351-363页

作者： Han LI Xu chang Key Laboratory of Petroleum Resource Research Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Innovation Academy for Earth Science Chinese Academy of SciencesBeijing 100029China

Reservoir reconstructions implemented in unconventional oil and gas exploration usually adopt hydraulic fracturing techniques to inject high-pressure fluid into the reservoir and change its pore-fracture connection structure to enhance *** fracturing changes the reservoir stress and causes the rocks to crack,thus generating microseismic *** important component of microseismic research is the source mechanism *** the research on the microseismic focal mechanism,information on the source mechanisms and in-situ stress status variations can be quantitatively revealed to effectively optimize the reservoir reconstruction design for increasing *** paper reviews the recent progress in hydraulic fracturing induced microseismic focal mechanism *** summarize their main principles and provide a detailed introduction of the research advances in source modeling,microseismic data synthesis,and focal mechanism *** also discuss the challenges and limitations in the current microseismic focal mechanism research and propose prospects for future research ideas and directions.

关键词： Unconventional oil and gas Microseismic monitoring Microseismic events Focal mechanism research

Bionic MEMS for Touching and Hearing Sensations: Recent Progress, Challenges, and Solutions

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Journal of Bionic Engineering 2022年第3期19卷 590-615页

作者： chang Ge Edmond Cretu Department of Electrical and Computer Engineering The University of British ColumbiaVancouverBCV6T 1Z4Canada

This paper reviews the recent progress on bionic microelectromechanical systems(MEMS)used for touching and hearing sensations,focusing on the following three types of devices:MEMS tactile sensors,MEMS directional microphones,and MEMS vector *** reviewing the electromechanical coupling principles,design,and performance of these MEMS devices,the authors conclude that it is vital for future research efforts in bionic MEMS to focus more on microfabrication *** development of robust microfabrication flows is the basis to implement hybrid electromechanical coupling principles based on novel functional ***-quality polymeric micromachining technologies can also significantly enhance the potential of existing bionic MEMS designs for more practical applications.

关键词： Bionic MEMS Tactile sensor Directional microphone Vector hydrophone Polymeric micromachining PDMS SU-8

Teleseismic shear wave splitting and intracontinental collision deformation of the northern Tibetan Plateau and the eastern Tarim basin

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Science China Earth Sciences 2023年第7期66卷 1556-1568页

作者： Lijun chang Chunyong WANG Institute of Geophysics China Earthquake AdministrationBeijing 100081China

Shear wave splitting measurement of teleseismic data has been used to determine the fast polarization directions and delay times for 38 temporary stations and 15 permanent stations from a NW linear seismic array across the eastern Tarim basin(ETB) and the northern Tibetan Plateau(NTP),and 10 permanent stations on both sides of the *** present an image of upper mantle anisotropy in the ETB and NTP using the 63 new *** results show that the fast directions and delay times have complex spatial distribution *** delay times within the interior of the Tarim basin are very small,with an average value of 0.6 s,which is not only smaller than that in the Altyn Tagh fault and Tianshan on the southern and northern margins of the basin,but also smaller than that in the NTP,reflecting that the delay time of stable blocks is smaller than that of active *** the array,from east to west,the fast directions contrarotate from NNW in the southern Songpan-Garze terrane to NW in the northern Songpan-Garze terrane,to near E-W or ENE in the north of the East Kunlun fault and southern margin of the Qaidam basin,then first abruptly rotate to NW in the Qiman Tagh fault on the northwestern margin of the Qaidam basin,second abruptly rotate to ENE in the Altyn Tagh fault and south of the ETB,and third abruptly rotate to NW in the north of the ETB,then finally rotate to WNW in the *** comparative analysis between the fast wave directions measured by shear wave splitting and predicted from the surface deformation field shows that,with the exclusion of the five observations with larger misfits within the interior of the ETB(with an average misfit of 27°),the misfits in the NTP and northern and southern margins of the Tarim basin are relatively small(with an average misfit of 9°).In addition,the fast wave directions of the tectonic units such as the Altyn Tagh fault,East Kunlun fault,and Tianshan are parallel to the strikes of faults and mountains i

关键词： Northern Tibetan Plateau Eastern Tarim basin Altyn Tagh fault East Kunlun fault Lithospheric deformation

Photonics Research Interview with Professor John Bowers

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Photonics Research 2023年第11期11卷 1987-1991页

作者： LIN chang School of Electronics Peking UniversityBeijing 100871China

The second interview for a Photonics Research webinar series took place on 28 November *** Lin chang interviewed his former PhD supervisor,*** Bowers,University of California,Santa Barbara,United *** is a world-renowned leader and entrepreneur in the field of integrated photonics for optics *** has founded many start-ups,including Terabit Technology,Calient Networks,Nexus Photonics,and *** top of these accomplishments,he's an impactful educator,giving advice and creating opportunities for many others.

关键词： interview optics Photonics

Resolution limit of mode-localised sensors

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Science China(Information Sciences) 2021年第4期64卷 198-207页

作者： Zhao ZHANG Honglong chang Ministry of Education Key Laboratory of Micro/Nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical University

In recent years, the mode localisation phenomenon of weakly coupled resonators has been successfully utilised to improve the sensitivity of microelectromechanical system(MEMS) sensors. However,controversy remians about the resolution limits of mode-localised sensors. This paper asks two questions of the community: what are the resolution limits of the mode-localised sensors, and can the resolution improvement be obtained using mode-localised sensing? To answer these questions, we report a series of resolution models of mode-localised sensors. We conclude that mode-localised sensing can realise a higher measuring resolution by orders of magnitude when more than three resonators are weakly coupled, and this will lay the theoretical foundation for a breakthrough for the MEMS sensors industry.

关键词： MEMS mode-localised sensors resolution limit 2-degree-of-freedom higher degree-of-freedom

Frequency Regulation of Power Systems With a Wind Farm by Sliding-Mode-Based Design

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IEEE/CAA Journal of Automatica Sinica 2022年第11期9卷 1980-1989页

作者： Zhiwen Deng chang Xu the College of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing 210098China

Load frequency regulation is an essential auxiliary service used in dealing with the challenge of frequency stability in power systems that utilize an increasing proportion of wind *** investigate a load frequency control method for multiarea interconnected power systems integrated with wind farms,aimed to eliminate the frequency deviation in each area and the tie-line power deviation between different *** method explores the derivative and integral terminal sliding mode control technology to solve the problem of load frequency *** technology employs the concept of relative ***,the subsystems of wind-integrated interconnected power systems have different relative degrees,complicating the control *** study develops the derivative and integral terminal sliding-mode-based controllers for these subsystems,realizing the load frequency ***,closed-loop stability is guaranteed with the theory of Lyapunov ***,both a thermal power system and a wind power system are applied to provide frequency support in this *** both constant and variable external disturbances,several numerical simulations were carried out in a two-area thermal power system with a wind *** results demonstrate the validity and feasibility of the developed method.

关键词： Load frequency control(LFC) power system sliding mode control(SMC) wind farm

Bound state noise-like pulses generation from composite filtering effects

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Optoelectronics Letters 2025年第3期 142-148页

作者： chang Qingyu ZHANG Caishi College of Physics & Optoelectronic Engineering Jinan University Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology School of Physics and Optoelectronic EngineeringMacau University of Science and Technology School of Innovation Engineering Macau University of Science and Technology

This paper demonstrated the generation of multi-wavelength bound state noise-like pulse (BNLP) in a dispersion-managed composite-filtered fiber laser consisting of nonlinear polarization rotation (NPR) and *** the case of BNLP,the generation is caused by the interaction between two noise-like pulses (NLPs) induced by the comb-filtering effect,and bound state level can be artificially controlled in the *** work provides a new method for generating low-coherence pulses and establishes a research idea for the study of the comb-filtering effects.

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