检索结果-南通市图书馆

International Journal of Mining Science and Technology 2017年第5期27卷 831-838页

作者： chang ping Xu Guang Department of Mining Engineering and Metallurgical Engineering Western Australian School of MinesCurtin UniversityKalgoorlie 6430Australia

The increasing use of diesel-powered equipment in confined spaces(underground mines) has the potential to over expose underground miners under the threat of diesel particulate matter(DPM). Miners in underground mines can be exposed to DPM concentrations far more than works in other industries. A great number of animal and epidemiological studies have shown that both short-term and long-term DPM exposure have adverse health effect. Based on reviews of related studies, especially some recent evidence, this paper investigated the long and short-term health effects based on animal studies and epidemiological studies. The exposure-response relationship studies were also explored and compared to the current DPM regulation or standards in some countries. This paper found that the DPM health effect studies specifically for miners are not sufficient to draw solid conclusions, and a recommendation limit of DPM concentration can be put in place for better protection of miners from DPM health risk. Current animal studies lack the use of species that have similar lung functions as human for understanding the cancer mode of action in human. And finally, the DPM health hazard will continue to be a challenging topic before the mode of action and reliable exposure-response relationship are established.

关键词： Diesel particulate matter (DPM) Underground mines Lung cancer Exposure-response relationship

Numerical study on DPM dispersion and distribution in an underground development face based on dynamic mesh

在线全文

学校读者我要写书评

暂无评论

International Journal of Mining Science and Technology 2020年第4期30卷 471-475页

作者： ping chang Guang Xu Jinxin Huang WA School of Mines MineralsEnergy and Chemical EngineeringCurtin UniversityKalgoorlieWA 6430Australia Department of Mining Engineering Missouri University of Science and TechnologyRollaMO 65409USA

In 2012,the International Agency for Research on Cancer(IARC)classified diesel particulate matter(DPM)as a carcinogen to *** the increased usage of diesel equipment in underground mines,miners have a high risk of over-exposure to DPM,which has drawn many concerns from the *** study used computational fluid dynamics(CFD)to analyse the DPM dispersion and concentration distribution characteristics in an underground development face based on an onsite *** DPM emitted from a moving loader under a forcing auxiliary ventilation system was *** motion of the load-haul-dump(LHD)in the tunnel was represented by a dynamic mesh *** species transport approach was applied to study the DPM *** DPM concentration zones were then identified based on the simulation *** results could provide guidelines for work practices and be helpful to an optimum auxiliary ventilation design to reduce underground miner exposure.

关键词： Diesel particulate matter Underground mines Ventilation Computational fluid dynamics Dynamic mesh

Preparation of the core-shell HMX@CS microparticles by biological excitation:Excellent hydrophobic-oleophilic properties and decreased impact sensitivity effectively

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2022年第5期18卷 855-861页

作者： Yue-qi Li Heng Zhai ping Ye Xing-quan Zhang chang-ping Guo Sichuan Co-Innovation Center for New Energetic Materials Southwest University of Science and Technology(SWUST)Mianyang621010PR China Analysis and Testing Center of Southwest University of Science and Technology(SWUST) Mianyang621010PR China

Inspired by the phenomenon of superhydrophobic plants and animals in nature,1,3,5,7-tetranitro-1,3,5,7-tetrazocane(HMX)@copper stearate(CS)core-shell composites with similar properties was prepared.A rough shell layer on the surface of the HMX was observed by scanning electron microscopy(SEM),and a series of in-depth characterization confirmed the successful generation of CS and the coreshell structure of the *** scanning calorimeter(DSC)proves that the crystal transition temperature(204℃)and high temperature decomposition exothermal temperature(284℃)of HMX@CS is almost unchanged compared with pure HMX,which means HMX and CS have good ***,the H50 of the samples also increased continuously(16.6 cm→33.7 cm)when the CS shell content increased from 1%to 5%,indicating that the CS shell has a certain buffering performance,and CS will absorb some heat and melt under the stimulation of impact due to its low melting point,which improved impact sensitivity of HMX effectively ***,HMX@CS has excellent hydrophobic and oleophilic performance,shows excellent wettability with lipid binder,and samples with appropriate CS shell content can continue to combustion stably after covering *** waterproof and low sensitivity coating provides a new way for the development of multifunctional energetic materials.

关键词： HMX Core-shell Sensitivity Hydrophobic-oleophilic Mechanical properties

Spacelike Mobius Hypersurfaces in Four Dimensional Lorentzian Space Form

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Sinica,English Series 2019年第4期35卷 519-536页

作者： Yan Bin LIN Ying Lü chang ping WANG College of Mathematics and Informatics Fujian Normal University School of Mathematical Sciences Xiamen University

In this paper, we first set up an alternative fundamental theory of M?bius geometry for any umbilic-free spacelike hypersurfaces in four dimensional Lorentzian space form, and prove the hypersurfaces can be determined completely by a system consisting of a function W and a tangent frame {E_i}. Then we give a complete classification for spacelike M?bius homogeneous hypersurfaces in four dimensional Lorentzian space form. They are either M?bius equivalent to spacelike Dupin hypersurfaces or to some cylinders constructed from logarithmic curves and hyperbolic logarithmic spirals. Some of them have parallel para-Blaschke tensors with non-vanishing M?bius form.

关键词： Mobius form Mobius metric para-Blaschke tensor Mobius homogeneous hypersurface hyperbolic logarithmic spiral Dupin hypersurface

Assessments on surface water resources and their vulnerability and adaptability in China

在线全文

学校读者我要写书评

暂无评论

Advances in Climate change Research 2020年第4期11卷 381-391页

作者： QIN Jia DING Yong-Jian ZHAO Qiu-Dong WANG Shao-ping chang Ya-ping State Key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China Key Laboratory of Eco-Hydrology Inland River Basin Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China University of Chinese Academy of Sciences Beijing100049China

A clear understanding of the changes of water resources under the background of environmental changes is of great significance for scientific management and utilization of water resources in *** study systematically analyzed the spatialetemporal variations of surface water resources in China since *** vulnerability in current(2010s)and its trends from 2000 to late-2010s in different regions of China were also *** addition,the correspondingly adaptive measures to counter regional risks to water resources were *** concluded that the runoff of major rivers had been decreasing in eastern China and increasing in western China during *** the arid area of Northwest China,the alpine runoff has shown an overall upward trend since the late-1990s/early-2000s,with a 10%-25% increase caused by the increase of glacial meltwater and *** the runoff of each hydrological station in the 2000s-2010s was 34.7% lower than that in the 1950se2010s on *** increases in precipitation and glacial meltwater with global warming caused a rapid expansion of lakes in the Qinghai-Tibet Plateau and Xinjiang,thus leading to an increase in total area and water quantity of lakes in China from 1995 to *** mean contribution rates of climate change and human activity to runoff change in river basins of China were 53.5% and 46.5%,respectively,during the period of *** driving factor of runoff change in many river basins has gradually changed from climate change(1950s-2000)to human activity(2000-2018).During 2000-2018,the contributions of human activities to runoff change were 50%-80% in major rivers of eastern *** vulnerability in most areas of Northwest China and North China is generally high,with the vulnerability index greater than ***,in Northeast,East,South,and Central China,it is lower or not *** Southwest China,the vulnerability varies greatly with Yunnan and Sichuan relatively low while Chon

关键词： Runoff change Lake area Surface water vulnerability Adaptation measures China

Metabolism of high density lipoproteins in liver cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第23期13卷 3159-3163页

作者： Jing-Ting Jiang Ning Xu chang-ping Wu Department of Tumor Biological Treatment the Third Affiliated Hospital of Suzhou University Changzhou 213003 Jiangsu Province China Section of Clinical Chemistry & Pharmacology Lund University S-221 85 Lund Sweden

Liver plays a vital role in the production and catabolism of plasma lipoproteins. It depends on the integrity of cellular function of liver, which ensures homeostasis of lipid and lipoprotein metabolism. When liver ca... 详细信息

关键词： High density lipoproteins Metabolism Liver cancer

Exact Solutions and Mode Transition for Out-of-Plane Vibrations of Non-uniform Beams with Variable Curvature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2016年第1期51卷 1-19页

作者： Sen-Yung Lee Shueei-Muh Lin Kai-ping chang Department of Mechanical Engineering National Cheng Kung UniversityTainanTaiwanRepublic of China Mechanical Engineering Department Kun Shan UniversityTainanTaiwan 710-03Republic of China

The two coupled governing differential equations for the out-of-plane vibrations of non-uniform beams with variable curvature are derived via the Hamilton’s *** equations are expressed in terms of flexural and torsional displacements *** this study,the analytical method is ***,two physical parameters are introduced to simplify the *** derives the explicit relations between the flexural and the torsional displacements which can also be used to reduce the difficulty in experimental *** on the relation,the two governing characteristic differential equations with variable coefficients can be uncoupled into a sixth-order ordinary differential equation in terms of the flexural displacement *** the material and geometric properties of the beam are in arbitrary polynomial forms,the exact solutions with regard to the outof-plane vibrations of non-uniform beams with variable curvature can be obtained by the recurrence *** addition,the mode transition mechanism is revealed and the influence of several parameters on the vibration of the non-uniform beam with variable curvature is explored.

关键词： Out-of-plane vibration Variable curvature Non-uniform beam Exact solution Mode transition

Serum VEGFR-3 and survival of advanced gastric cancer patients treated with FOLFOX

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第17期16卷 2163-2169页

作者： Ni, Xue-Feng Wu, chang-ping Jiang, Jing-Ting Soochow Univ Affiliated Hosp 3 Dept Oncol Changzhou 213003 Jiangsu Prov Peoples R China

AIM: To explore if vascular endothelial growth factor receptor-3 (VEGFR-3) and carcinoembryonic antigen (CEA) can predict overall survival in advanced gastric ***: VEGFR-3 level was assessed by enzymelinked immunosorbent assay,and CEA was assessed by chemiluminescence immunoassay in the sera of 81 advanced gastric cancer patients before treatment with oxaliplatin plus 5-fluorouracil and folinic ***: Median survival time in patients with a low serum VEGFR-3 level was significantly longer than in those with a higher VEGFR-3 level (15.4 mo vs 7.7 mo,P < 0.001).Patients with a low CEA level had a longer survival than those with a higher CEA level (15.8 mo vs 8.6 mo,P < 0.001).Thirty-nine patients with low VEGFR-3 and low CEA levels had a median survival of 19.7 mo (P = 0.0006).The hazard ratio for patients with a high VEGFR-3 level was 2.443 (P = 0.002).CONCLUSION: High serum VEGFR-3 level is correlated significantly with poor *** patients with a high serum level of VEGFR-3,alternative chemotherapy regimens should be considered.

关键词： Stomach neoplasms Vascular endothelial growth factor receptor-3 Carcinoembryonic antigen Oxaliplatin plus 5-fluorouracil and folinic acid protocol Survival

Efflux pump gene hefA of Helicobacter pylori plays an important role in multidrug resistance

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第33期14卷 5217-5222页

作者： Zhi-Qiang Liu Peng-Yuan Zheng ping-chang Yang Department of Gastroenterology the Second Affiliated Hospital of Zhengzhou University Zhengzhou 450014 Henan Province China Department of Pathology and Molecular Medicine McMaster University Hamilton Ontario L8N 4A6 Canada

AIM: To determine whether efflux systems contribute to multidrug resistance of H pylori. METHODS: A chloramphenicol-induced multidrug resistance model of six susceptible H pylori strains (5 isolates and H pylori NCTC11637) was developed. Multidrug-resistant (MDR) strains were selected and the minimal inhibitory concentration (MIC) of eryth-romycin, metronidazole, penicillin G, tetracycline, and ciprofloxacin in multidrug resistant strains and their parent strains was determined by agar dilution tests. The level of mRNA expression of hefA was assessed by fluorescence real-time quantitative PCR. A H pylori LZ1026 knockout mutant (ΔH pylori LZ1026) for (puta-tive) efflux protein was constructed by inserting the kanamycin resistance cassette from pEGFP-N2 into hefA, and its susceptibility profiles to 10 antibiotics were evaluated. RESULTS: The MIC of six multidrug-resistant strains (including 5 clinical isolates and H pylori NCTC11637) increased signifi cantly (≥ 4-fold) compared with their parent strains. The expression level of hefA gene was significantly higher in the MDR strains than in their parent strains (P = 0.033). A H pylori LZ1026 mutant was successfully constructed and the ΔH pylori LZ1026 was more susceptible to four of the 10 antibiotics. All the 20 strains displayed transcripts for hefA that con-fi rmed the in vitro expression of these ***: The efflux pump gene hefA plays an important role in multidrug resistance of H pylori.

关键词： Efflux pump Helicobacter pylori Multidrug resistance Fluorescence real-time quantitative PCR Knockout mutant

NUMERICAL PREDICTION OF PROPELLER EXCITED ACOUSTIC RESPONSE OF SUBMARINE STRUCTURE BASED ON CFD,FEM AND BEM

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2012年第2期24卷 207-216页

作者： WEI Ying-san WANG Yong-sheng chang Shu-ping FU Jian Department of Mechanical Engineering Naval University of EngineeringWuhan 430033China

A mesh-less Refined Integral Algorithm （RIA） of Boundary Element Method （BEM） is proposed to accurately solve the Helmholtz Integral Equation （HIE）.The convergence behavior and the practicability of the method are *** Fluid Dynamics （CFD）,Finite Element Method （FEM） and RIA are used to predict the propeller excited underwater noise of the submarine hull *** the propeller and submarine＇s flows are independently validated,then the self propulsion of the ＂submarine＋propeller＂ system is simulated via CFD and the balanced point of the system is determined as well as the self propulsion ***,the transient response of the ＂submarine＋ propeller＂ system is analyzed at the balanced point,and the propeller thrust and torque excitations are *** the thrust and the torque excitations of the propeller are loaded on the submarine,respectively,to calculate the acoustic response,and the sound power and the main peak frequencies are *** show that：（1） the thrust mainly excites the submarine axial mode and the high frequency area appears at the two conical-type ends,while the torque mainly excites the circumferential mode and the high frequency area appears at the broadside of the cylindrical section,but with rather smaller sound power and radiation efficiency than the former,（2） the main sound source appears at BPF and 2BPF and comes from the harmonic propeller ***,the main attention should be paid on the thrust excitation control for the sound reduction of the propeller excited submarine structure.

关键词： submarine propeller excitation self propulsion underwater noise Computational Fluid Dynamics (CFD) Finite Element Method (FEM) and Refined Integral Algorithm (RIA)