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Involvement of connexin 43 in acupuncture analgesia

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Chinese Medical Journal 2009年第1期122卷 54-60页

作者： HUANG Guang-ying ZHENG Cui-hong YU wei-chang TIAN Dai-shi WANG wei Institute of Integrated Traditional and Western Medicine Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China Department of Neurology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei 430030 China

Background Connexin 43 （Cx43） is one of the major components of human keratinocyte gap junctions. To study whether gap junctional intercellular communication participates in the transfer of acupoint signals and acupuncture analgesia, the expression of Cx43 was studied in Zusanli （ST36） acupoints compared with control non-acupoint regions in rats after acupuncture. In addition, Cx43 heterozygous gene knockout mice were used to further explore the relationship between Cx43 and acupuncture analgesia.Methods The expression of Cx43 was detected by immunohistochemistry, immunoblotting, and RT-PCR for the Cx43 protein and mRNA. The influence of the Cx43 gene knockout on acupuncture analgesia was measured by a hot plate and observing the writhing response on Cx43 heterozygous gene knockout mice. Results Immunohistochemistry showed abundant Cx43 expression in some cells in the skin and subcutaneous tissue of rat ST36 acupoints. The mRNA and protein levels of Cx43 in acupoints were significantly higher than those in the control points in the non-acupuncture group, and even more so after acupuncture. The hot plate and writhing response experiments showed that partial knockout of the Cx43 gene decreased acupuncture analgesia. Conclusion Cx43 expression and acupuncture analgesia showed a positive correlation.

关键词： connexin 43 gene knockout acupuncture analgesia hot plate test writhing response

当代中国社会二阶冲突的特点、原因及应对策略

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河北学刊 2011年第3期31卷 116-120页

作者：常健韦长伟南开大学周恩来政府管理学院天津300071

二阶冲突是由第三方干预所导致的各方与第三方之间的冲突,是冲突升级和扩散的一种激烈形式。当代中国社会二阶冲突频发的根源在于公众对政府"高依赖、低信任"的现实困境。产生二阶冲突的直接动因包括通过政府向对方施压,出于失望而认为... 详细信息

二阶冲突是由第三方干预所导致的各方与第三方之间的冲突,是冲突升级和扩散的一种激烈形式。当代中国社会二阶冲突频发的根源在于公众对政府"高依赖、低信任"的现实困境。产生二阶冲突的直接动因包括通过政府向对方施压,出于失望而认为干预不足,失去信任而认为干预不公,出于恐惧而引发关注,出于无能的转移性攻击等。二阶冲突的激发因素包括针对第三方的谣言和第三方超预期的刺激性处置方式。二阶冲突的促成条件包括冲突方的大规模聚集及试探性挑衅未遇到阻抗等。防范二阶冲突发生的主要方法包括发展民间第三方干预机制,遵循公平的冲突处置程序,保持信息公开及时,建立严格的执法程序,防止群体性思维、情绪和行动,以及针对形成二阶冲突的不同动机进行相应安抚。

关键词：二阶冲突公共冲突第三方干预

The analysis of genetic diversity and differentiation of six Chinese cattle populations using microsatellite markers

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Journal of Genetics and Genomics 2008年第1期35卷 25-32页

作者： Yongjiang Mao Hong chang Zhangping Yang Liu Zhang Ming Xu Guobin chang wei Sun Guangming Song Dejun Ji Animal Science and Technology College Yangzhou University Yangzhou 225009 China

A total of 321 individuals from six cattle populations of four species in a bovine subfamily in China were studied using 12 pairs of microsatellite markers. The genetic diversities within and between populations were calculated. The phylogenetic trees were constructed by （δμ）^2 and DA distances, and the divergence times between populations were estimated by （δμ）^2. Altogether, 144 microsatellite alleles were detected including 24 private alleles and nine shared alleles. Chinese Holstein had the largest number of private alleles （10）, whereas Bohai black and Buffalo had the smallest number of private alleles （2）. Chinese Holstein showed the highest genetic variability. Its observed number of alleles （Na）, mean effective number of alleles （MNA）, and mean heterozygosity （He） were 7.7500, 4.9722, and 0.7719, respectively, whereas, the Buffalo and Yak showed low genetic variability. In the phylogenetic trees, Luxi and Holstein grouped first, followed by Bohai and Minnan. Yak branched next and buffalo emerged as the most divergent population from other cattle populations. Luxi and Bohai were estimated to have diverged 0.039-0.105 million years ago （MYA）, however, buffalo and Holstein diverged 0.501-1.337 MYA. The divergence time of Yak versus Minnan, Holstein and buffalo was 0.136-0.363, 0.273-0.729, and 0.326-0.600 MYA, respectively.

关键词： genetic diversity genetic differentiation microsatellite bovine subfamily

Synthesis of magnetic core-shell iron nanochains for potential applications in Cr(Ⅵ)ion pollution treatment

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Rare Metals 2021年第1期40卷 176-179页

作者： Hai-Feng Feng You-Xing Yu Shi-Qi Jiang Jun Shang Yan Cheng Liang Wang wei-chang Hao Tian-Min Wang , School of Materials Science and Engineering Beihang UniversityBeijing 100191China Center of Materials Physics and Chemistry and Department of Physics Beihang UniversityBeijing 100191China

Fe nanochains with diameters of 50-150 nm and average length of about 1μm were synthesized by titrating NaBH_(4)solution into FeCl_(2) aqueous solution(i.e.,reduction of Fe(II)ions).The microstructures and magnetic properties were studied by X-ray diffraction(XRD),transmission electron microscope(TEM),and vibrating sample magnetometer(VSM).The results reveal that the nanochains have a core-shell structure with a-Fe as the core and amorphous iron oxide as the *** Fe coreshell nanochains show the characteristic of soft magnetic materials,achieving the highest magnetization of200.74 mA-m^(2)·g^(-1).The influences of the titrating rate of NaBH_(4)aqueous solution on the morphology of the Fe nanochains were also *** reveals that low titrating rate is beneficial for synthesizing Fe nanochains with uniform *** reduction experiments indicate that these Fe nanochains are of high *** 90%Cr(VI)ions are successfully removed after 10 min reaction of 100 mg Fe nanochains in the 100 ml K_(2)Cr_(2)O_(7) solution(100 mg·L^(-1))and more than 99%after 30 min.

关键词： Fe nanochains Core-shell structure Magnetic properties Reduction of Cr(Ⅵ)ion

Promotional effects of cerium doping and NO_x on the catalytic soot combustion over MnMgAlO hydrotalcite-based mixed oxides

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Journal of Rare Earths 2014年第2期32卷 176-183页

作者：李倩王晓常伟陈慧张昭良 School of Chemistry and Chemical Engineering Shandong Provincial Key Laboratory of Fluorine Chemistry and Chemical MaterialsUniversity of Jinan

A series of MnMgA10 samples with different amounts of Ce doping were facilely prepared using coprecipitation method and their catalytic soot combustion activity was evaluated by temperature programmed oxidation reaction （TPO）. The methods of X-ray diffraction （XRD）, Brumauer-Emmett-Teller （BET）, H2-TPR, NO-TPO and in situ 1R were used to characterize the physio- chemical properties of these samples. Dopant Ce improved the soot combustion performance of MnMgA10 catalyst due to the en- hanced redox ability. Introduction of NOx led to the further increase of catalytic soot oxidation activity on these samples. Over Ce-containing samples, the catalytic activity was slightly decreased as the amount of dopant Ce increased in 02. Diftbrently, in NO＋O2, a certain amount of dopant Ce was much more favorable and excess amount of Ce resulted in a sharp drop of the catalytic soot combustion activity. Both NO： and nitrates were found to have great contributions to the effects of NOx on the soot combustion activity of Ce-doped catalysts. More NO2 was generated as dopant Ce increased. When appropriate amount of Ce was introduced, the as-formed NO2 was stored as bridging bidentate nitrate on Mn-Ce site, which was confirmed to have higher reactivity with soot than nitrite or monodentate nitrate on Mn and/or Ce sites. Overall, ***.90 was considered as the most potential catalyst for soot combustion.

关键词： hydrotalcite soot combustion NO2 bridging bidentate nitrate monodentate nitrate rare earths

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灰色模型GM(1,1)的一种新优化方法

系统工程理论与实践 2007年第4期27卷 141-146页

作者：张怡魏勇熊常伟西华师范大学数学与信息学院南充637002

根据灰色系统理论的新息优先原理,提出了将X(1)的第n个分量作为灰色微分模型的初始条件与优化背景值相结合的方法,对GM(1,1)模型进行了改进,改进后的模型既适用于低增长指数序列建模,也适用于高增长指数序列建模,尤其是对高增长指数序列... 详细信息

根据灰色系统理论的新息优先原理,提出了将X(1)的第n个分量作为灰色微分模型的初始条件与优化背景值相结合的方法,对GM(1,1)模型进行了改进,改进后的模型既适用于低增长指数序列建模,也适用于高增长指数序列建模,尤其是对高增长指数序列,改进的GM(1,1)模型的模拟精度与预测精度都有提高,即使在发展系数|a|大于2时,新模型的拟合精度仍然很高.

关键词： GM(1,1)模型背景值初始条件

Non-tax Revenue and Local Economic Growth --The Case of Taiwan

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经济管理学刊（中英文版） 2015年第1期4卷 8-14页

作者： Hsiu-wei chang Yi-Chung Hsu Department of Public Finance and Taxation National Taichung University of Science and Technology Taichung Taiwan

The chronic health effects after exposure toPCDD/Fs and methylmercury near a highly contaminated Area

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The chronic health effects after exposure toPCDD/Fs and meth...

Experimental and numerical studies on vibration characteristics of a railway embankment

2013第七届海峡两岸毒理学研讨会

作者：李俊璋 Jung-wei chang Department of Environmental and Occupational Health/Research Center of Environmental Trace Toxic Substance National Cheng Kung University

＜正＞An-Shun chloralkali plant in the northwestern section of Tainan City,Taiwan, manufactured caustic soda,hydrochloric acid,liquid chlorine using chloralkali electrolysis and pentachlorophenol（PCP） from 1942 to 1979,after which it was *** the manufacturing process,a great deal of mercury-contaminated sludge and wastewater were discharged into the nearby ecosystem and then methylated and bio-accumulated in aquatic ***/Fs are byproducts of PCP manufacturing.A preliminary investigation showed

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Journal of Central South University 2022年第5期29卷 1641-1652页

作者： YANG chang-wei YUAN Cheng QU Li-ming DING Xuan-ming LIU wei-bin School of Civil Engineering Southwest Jiaotong UniversityChengdu 610031China Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengdu 610031China School of Civil Engineering Chongqing UniversityChongqing 400045China China Academy of Railway Sciences Corporation Limited Beijing 100081China

In order to study the dynamic response of the rail embankment under different speeds and moving load of following vehicles,a model experiment with a ratio of 1:10 is established to test the time history of acceleration and the earth pressure of the embankment at various train *** the ABAQUS finite element calculation software,a train load is applied through the FORTRAN subroutine,thereby establishing a three-dimensional finite element model with the same size as the model *** data and conclusions of the finite element method model are verified by the model *** model also makes some supplements to the model *** experimental results show that with the increase of speed,the peak acceleration and earth pressure of the embankment also *** analyzing the experimental data,it can also be found that the vertical acceleration of the embankment is much greater than the axial acceleration and the lateral *** addition,the elastic modulus of the soil and the sleeper pitch also have some influence on the acceleration.

关键词： railway embankment vibration acceleration model experiment finite element modelling moving loads