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Fabrication of two-layer flexible copper clad laminate by electroless-Cu plating on surface modified polyimide

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中国有色金属学会会刊：英文版 2009年第4期19卷 970-974页

作者： Soo-min HWANG Jun-Hyung LIM chang-min lee Eui-Cheol PARK Jun-Hyuk CHOI Jinho JOO Hoo-Jeong lee Seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

A flexible copper clad laminate(FCCL) was fabricated using electroless-and electro-Cu plating processes and the effects of pre-treatment time on the adhesion strength of the FCCL were evaluated based on interfacial *** neutralization and catalyst time were varied in the range of 0-20 min and 0.1-10 min,respectively,and the interfacial condition of the FCCL was characterized by atomic force microscopy(AFM) and X-ray photoelectron spectroscopy(XPS).It is observed that the peel strength increases significantly as the neutralization and catalyst time *** strength as high as 7.2-7.3 N/cm is obtained as the neutralization and catalyst time increase up to 20 min and 10 min,respectively,which is comparable to the strength achieved by the conventional laminating and sputtering *** improvements are probably due to an increase in the surface roughness of polyimide(PI),the activated surface condition,and the adsorption of palladium ions/atoms(Pd) on the PI surface which act as nucleation sites for Cu.

关键词：聚酰亚胺表面改性化学制备层压板铜电镀铜箔软性 X射线光电子能谱

Characterization of flexible copper laminates fabricated by Cu electro-plating process

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中国有色金属学会会刊：英文版 2009年第4期19卷 965-969页

作者： chang-min lee Jun-Hyung LIM Soo-min HWANG Eui-Cheol PARK Jong-Hyun SHIM Jin-Hyun PARK Jinho JOO Seung-Boo JUNG School of Advanced Materials Science and Engineering Sungkyunkwan University

Flexible copper clad laminates(FCCLs) were fabricated using the electro-plating process and the combined effect of the current density and plating time on their surface morphology,texture,hardness,electrical resistivity and folding behavior was *** achieve Cu layers with similar thicknesses,the current density was varied in the range of 0.2-3 A/dm2 and the plating time was controlled in the range of 0.5-7.5 h to compensate for the variation of the current *** surface morphology,hardness,and folding behavior were characterized by atomic force microscopy,nanoindentation technique and Massachusett Institute of Technology folding endurance test,*** X-ray diffraction patterns indicated that the Cu phase was formed without any secondary phases;however,the preferred orientation changed from(220) to(111) as the current density increased over 1 A/*** addition,it was observed that the root-mean-square and hardness values decreased when the current density increased and the plating time decreased *** electrical resistivity was as low as approximately 21 nΩ·m and the number of cycles without failure in the folding test was over 15 000,which were comparable to those of commercial FCCLs.

关键词：电镀工艺层压板铜层制备表征电流密度原子力显微镜纳米压痕技术

Ectopic peritoneal paragonimiasis mimicking tuberculous peritonitis:A care report

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World Journal of Clinical Cases 2022年第16期10卷 5359-5364页

作者： Jung Woo Choi chang min lee Seong Je Kim Se In Hah Ji Yoon Kwak Hyun Chin Cho chang Yoon Ha Woon Tae Jung Ok Jae lee Department of Internal Medicine Gyeongsang National University College of Medicine and Gyeongsang National University HospitalJinju 52727South Korea Institute of Health Sciences Gyeongsang National UniversityJinju 52828South Korea

BACKGROUND The most common site of paragonimiasis is in the *** migratory route passes through the duodenal wall,peritoneum,and diaphragm to the lungs;thus,the thoracic cavity and central nervous system,as well as the liver,intestine,and abdominal cavity may be ***,we present a case of intraperitoneal paragonimiasis without other organ involvement,mimicking tuberculous *** SUMMARY A 57-year-old man presented with recurrent abdominal pain for 4 *** examination revealed tenderness in the right lower *** findings showed complete blood counts within the normal range without *** reactive lymph nodes and diffuse peritoneal infiltration were noted on abdominal computed tomography(CT).There were no abnormalities on chest CT or *** findings of diagnostic laparoscopy for the differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis included multiple small whitish nodules and an abscess in the *** reports confirmed the presence of numerous eggs of Paragonimus westermani(***).A postoperative serum enzyme-linked immunosorbent assay revealed *** *** and repetitive history-taking led him to retrospectively recall the consumption of freshwater *** 3 d of treatment with praziquantel(1800 mg;25 mg/kg),he recovered from all *** In patients who require diagnostic laparoscopy for the differential diagnosis of tuberculous peritonitis and peritoneal carcinomatosis,repetitive history-taking and preoperative serologic antibody tests against Paragonimus may be helpful in diagnosing intraperitoneal paragonimiasis without other organ involvement.

关键词： Differential diagnoses Intraperitoneal abscess Paragonimiasis Paragonimus westermani Peritonitis Tuberculosis Case report

Length of negative resection margin does not affect local recurrence and survival in the patients with gastric cancer

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World Journal of Gastroenterology 2014年第30期20卷 10518-10524页

作者： chang min lee Ye Seob Jee Ju-Hee lee Sang-Yong Son Sang-Hoon Ahn Do Joong Park Hyung-Ho Kim Department of Surgery Seoul National University Bundang HospitalSeongnam 463-707South Korea Department of Surgery Dankook University HospitalCheonan 330-715South Korea Colledge of Medicine Dankook UniversityCheonan 330-715South Korea Department of Surgery Hanyang University Medical CenterSeoul 133-792South Korea Colledge of Medicine Seoul National UniversitySeoul 110-799South Korea

AIM: To investigate the influence of the resection margin on local recurrence and survival in gastric cancer patients.

关键词： Gastric cancer Survival Recurrence Resection Margin

Roles of humidity and heat treatment temperatures on YBa_2Cu_3O_(7-x) coated conductors by trifluoroacetic acid-metal organic deposition process

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中国有色金属学会会刊：英文版 2009年第4期19卷 956-960页

作者： Seok-Hern JANG Jun-Hyung LIM chang-min lee Eui-Cheol PARK Soo-min HWANG Jun-Hyuk CHOI Jong-Hyun SHIM Jin-Hyun PARK Won KIM Jinho JOO School of Advanced Materials Science and Engineering Sungkyunkwan University

YBa2Cu3O7-x(YBCO) films were fabricated on an LAO substrate using the trifluoroacetic acid-metal organic deposition(TFA-MOD) method and the effects of the humidity and heat treatment temperatures on the microstructure,degree of texture and critical properties of the films were *** order to understand the combined effects of the humidity and the calcining and firing temperatures on critical properties,heat-treatment was performed at various temperatures with the other processing variables *** films were calcined at 400-430 ℃ and fired at 750-800 ℃ in a 0-12.1% humidified Ar-O2 *** texture was determined by pole-figure *** amount of the BaF2 phase was effectively reduced and a sharp and strong biaxial texture was formed under a humidified atmosphere,which led to increased critical *** addition,the microstructure varied significantly with firing temperature but changed little with calcining *** highest IC of 40 A/cm-width,which corresponds to JC value of 1.8 MA/cm2,was obtained for the films fired at 775 ℃(in 12.1% humidity) after calcining at 400-430 ℃.It is likely that the highest IC value is due to the formation of a more pure YBCO phase,c-axis grains,and a denser microstructure.

关键词： YBa2Cu3O7 热处理温度三氟乙酸沉积过程湿度涂层导体有机金属微观结构变化

Exploring ideal operative time for best outcomes in gastric cancer surgery:A multi-institutional study based on KLASS-07 database

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Chinese Journal of Cancer Research 2023年第6期35卷 660-674页

作者： Shin-Hoo Park Ye-Rim Shin Hoon Hur chang min lee Jae Seok min Seung Wan Ryu Hyun Dong Chae Oh Jeong chang-In Choi Kyo-Young Song Ho Goon Kim Ye Seob Jee Kwang Hee Kim Jeong Goo Kim Kyung Sook Yang Hua Huang Sungsoo Park Division of Foregut Surgery Korea University College of MedicineSeoul 02841Republic of Korea Division of Foregut Surgery Korea University Anam HospitalSeoul 02841Republic of Korea Department of Surgery Ajou University School of MedicineSuwon 16499Republic of Korea Division of Foregut Surgery Korea University Ansan HospitalAnsan 15355Republic of Korea Department of Surgery Dongnam Institute of Radiological and Medical SciencesCancer CenterBusan 46033Republic of Korea Department of Surgery Keimyung University Dongsan Medical CenterDaegu 41931Republic of Korea Department of Surgery Catholic University of Daegu School of MedicineDaegu 42472Republic of Korea Department of Surgery Chonnam National University Medical SchoolHwasun 58128Republic of Korea Department of Surgery Pusan National University HospitalPusan 49241Republic of Korea Department of Surgery Catholic University of Seoul St Mary’s HospitalSeoul 06591Republic of Korea Department of Surgery Chonnam National University Medical SchoolGwangju 61469Republic of Korea Department of Surgery Dankook University College of MedicineCheonan 31116Republic of Korea Department of Surgery Busan Paik HospitalInje UniversityBusan 14905Republic of Korea Department of Surgery Daejeon St.Mary’s HospitalCollege of Medicinethe Catholic University of KoreaDaejeon 34943Republic of Korea Department of Biostatistics Korea University College of MedicineSeoul 02841Republic of Korea Department of Gastric Cancer and Soft Tissue Sarcoma Fudan University Shanghai Cancer CenterShanghai 200433China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200433China

Objective:While a rushed operation can omit essential procedures,prolonged operative time results in higher ***,the optimal operative time range remains *** study aimed to estimate the ideal operative time range and evaluate its applicability in laparoscopic cancer ***:A prospectively collected multicenter database of 397 patients who underwent laparoscopic distal gastrectomy were retrospectively *** ideal operative time range was statistically calculated by separately analyzing the operative time of uneventful ***,intraoperative and postoperative outcomes were compared among the shorter,ideal,and longer operative time ***:The statistically calculated ideal operative time was 135.4-165.4 *** longer operative time(LOT)group had a lower rate of uneventful,perfect surgery than the ideal or shorter operative time(IOT/SOT)group(2.8%vs.8.8%and 2.2%vs.13.4%,all Pleeding,postoperative morbidities,and delayed diet and discharge(all Pmin)should be *** the essential operative procedure were faithfully conducted without compromising oncological safety,an operative time shorter than the ideal range leaded to a better *** to minimize operative time should be attempted with sufficient surgical experience.

关键词： Operative time laparoscopic surgery gastric cancer gastrectomy morbidity

Oncometabolic surgery:Emergence and legitimacy for investigation

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Chinese Journal of Cancer Research 2020年第2期32卷 252-262页

作者： Won Jun Kim Yeongkeun Kwon chang min lee Seung Hyun Lim Yong Li Junjiang Wang Weixian Hu Jiabin Zheng Gang Zhao Chunchao Zhu Wei Wang Wenjun Xiong Quan Wang mingjie Xia Sungsoo Park Korea University College of Medicine Seoul 136-701Republic of Korea Division of Foregut Surgery Korea University College of MedicineSeoul 136-701Republic of Korea Department of General Surgery Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Department of Gastrointestinal Surgery Shanghai Jiao Tong University School of MedicineRenji HospitalShanghai 200025China Department of Gastrointestinal Surgery Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120China Department of Gastrointestinal Surgery The First Bethune Hospital of Jilin UniversityChangchun 130021China

Studies on morbid obesity have shown remarkable improvement of diabetes in patients who have undergone bariatric *** was subsequently shown that these operations induce diabetes remission independent of the resultant weight loss;as a result,surgeons began to investigate whether operations for gastric cancer(GC)could have the same beneficial effect on diabetes as bariatric *** was then shown in multiple reports that followed that certain operations for GC were able to improve or even cure type 2 diabetes mellitus(T2 DM)in GC *** finding gave rise to the concept of"oncometabolic surgery",in which a patient diagnosed with both GC and T2 DM undergo a single operation with the purpose of treating both *** the increasing incidence of T2 DM,oncometabolic surgery has the potential to improve the quality of life and even extend survival of many GC ***,because the GC patient population and the bariatric patient population are wildly different and because different GC operations have different properties,the effect of oncometabolic surgery must be carefully assessed and engineered in order to maximize benefit and avoid *** manuscript aims to summarize the findings made so far in the field of oncometabolic surgery and to provide an outlook regarding the possibility of oncometabolic surgery being incorporated into standard clinical practice.

关键词： Stomach neoplasms bariatric surgery diabetes mellitus metabolic syndrome gastric bypass

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直肠癌下切缘收缩性研究

直肠癌下切缘收缩性研究

作者：李昌敏（chang min lee）大连医科大学

学位级别：硕士

目的:直肠癌下切缘直接关系到手术是否做到根治,患者术后生活质量及远期生存率。临床医生及专家学者对安全下切缘问题进行过大量研究,但是由于直肠在不同状态下具有收缩性,因此术中下切缘长度与术后下切缘长度存在差异。因此我们做此研... 详细信息

目的:直肠癌下切缘直接关系到手术是否做到根治,患者术后生活质量及远期生存率。临床医生及专家学者对安全下切缘问题进行过大量研究,但是由于直肠在不同状态下具有收缩性,因此术中下切缘长度与术后下切缘长度存在差异。因此我们做此研究,旨在:1、对直肠癌前切除术标本在不同状态进行测量,研究其变化规律;2根据直肠癌标本在不同状态下变化规律,为临床上判断合适下切缘长度提供依据。方法:选择于本院行直肠癌根治术且临床上无远处转移的患者30例,患者术前检查均无明显心、肺功能异常,均能耐受手术。对每例直肠癌标本在肿瘤上方至近切缘下方之间沿直肠纵轴任选取两点并用手术线打线结做好标记,然后在不同状态下进行测量两线结间的肠段长度:(1)术中游离直肠;(2)新鲜离体直肠标本(标本离体后即刻测量);(3)离体30min后直肠标本;(4)甲醛固定12-24h后直肠。通过测得直肠在不同状态下两标记点间肠段长度,计算肠段在不同状态下的收缩率。结果:1、术中直肠两标记点间肠段长度与离体新鲜直肠标本中两标记点间肠段肠长度、离体30min后直肠标本中两标记点间的肠段长度及甲醛固定后直肠标本中两标记点间的肠段长度其均值分别为:4.86±1.52cm,3.77±1.22cm,3.16±1.12cm,2.54±0.86cm。经单因素方差分析表明其均数有显著差异(Pmin后标本两标记点间肠段长度/术中标本两标记间肠段长度=58.46%-75.71%,平均收缩比率为65.45%;(3)甲醛固定后标本两标记点间肠段长度/术中直肠标本两标记点间肠段长度=38.70%-66.66%,平均收缩比率为52.25%。2两标记点间肠段长度取任意值,通过所测得数值发现:两标记点间肠段长度与肠管收缩性无明显关系(R2=0.0034)。即实验过程中所取两线结间肠段长度对实验无明显影响。结论:1.通过研究发现直肠下切缘在不同状态下具有收缩性,标本经甲醛固定后相对于术中标本收缩了47.73%,收缩了接近一半。2.对直肠癌根治术肿瘤下切缘的判断应考虑到直肠的收缩性,从而得到真正安全的下切缘。

关键词：直肠癌直肠癌全系膜切除术安全下切缘收缩性

Efficacy and safety of rebamipide/nizatidine in patients with erosive gastritis: A randomized, multicenter, phase 4 study

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World Journal of Gastroenterology 2024年第48期30卷 5152-5161页

作者： Donghoon Kang Myung-Gyu Choi Ki-Nam Shim Hye-Kyung Jung Seung-Joo Nam Jung Ho Park Sang Gyun Kim Nam-Hoon Kim Su Jin Hong Tae Joo Jeon Jae Il Chung Hang Lak lee Ju Yup lee Tae Oh Kim chang min lee Sun Moon Kim Jeong-Hwan Kim Jang Eon Kim Jeong Seop Moon Ho Dong Kim Wan-Sik lee Hong Jun Park Department of Internal Medicine Seoul St.Mary’s HospitalThe Catholic University of KoreaSeoul 06591South Korea Department of Internal Medicine Ewha Womans University Seoul HospitalGastroenterology and Hepatology CenterSeoul 07985South Korea Department of Internal Medicine Ewha Womans University Mokdong HospitalSeoul 07985South Korea Department of Internal Medicine Kangwon National University School of MedicineChuncheon 24289South Korea Department of Medicine Kangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoul 03181South Korea Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul 03080South Korea Department of Internal Medicine Ilsan Paik HospitalInje University College of MedicineGoyang 10380South Korea Department of Internal Medicine Digestive Disease CenterSoonchunhyang University Bucheon HospitalBucheon 31538South Korea Department of Internal Medicine Inje University College of MedicineSanggye Paik HospitalSeoul 01757South Korea Department of Gastroenterology Sahmyook Medical CenterSeoul 02500South Korea Department of Internal Medicine Hanyang University College of MedicineSeoul 04763South Korea Department of Internal Medicine Keimyung University School of MedicineDaegu 42601South Korea Department of Internal Medicine Inje University Haeundae Paik HospitalInje University College of MedicineBusan 48108South Korea Department of Internal Medicine Gyeongsang National University School of MedicineGyeongsang National University HospitalJinju 52727South Korea Department of Internal Medicine Konyang University HospitalDaejeon 35365South Korea Gastroenterology Center Konkuk University Medical CenterSeoul 05030South Korea Department of Gastroenterology Seoul Medical CenterSeoul 02053South Korea Department of Gastroenterology Inje University Busan Paik HospitalBusan 47392South Korea Department of Gastroenterology St.Carollo HospitalSooncheon 57931South Korea Division of Gastroenterology Department of Internal

BACKGROUND For the treatment of gastritis,rebamipide,a mucoprotective agent,and nizatidine,a gastric acid suppressant,are commonly employed *** To compare the efficacy of Mucotra®SR(rebamipide 150 mg)and Axid®(nizatidine 150 mg)combination therapy with the sole administration of Axid®in managing erosive *** A total of 260 patients diagnosed with endoscopically confirmed erosive gastritis were enrolled in this open-label,multicenter,randomized,phase 4 clinical trial,allocating them into two groups:Rebamipide/nizatidine combination twice daily vs nizatidine twice daily for 2 *** full-analysis set analysis encompassed 239 patients(rebamipide/nizatidine,n=121;nizatidine,n=118),while the per-protocol analysis included 218 patients(n=110 vs 108).Post-treatment assessments comprised primary(erosion improvement rate)and secondary(erosion and edema cure rates,erythema improvement rates,hemorrhage,and gastrointestinal symptoms)***,drug-related adverse effects were *** Primary efficacy assessment showed a statistically significant improvement rate in mucosal erosions in the combination group compared to the control group in the full-analysis set(rebamipide/nizatidine 62.0%,nizatidine 49.2%,P=0.046),with a similar trend noted in the per-protocol analysis(62.7%vs 50.0%,P=0.058).Both groups were effective in curing erosion and edema and improvement of bleeding,erythema,and gastrointestinal symptoms,whereas no inter-group differences were *** confined to the participants with gastritis symptoms,improvement of erosion was more optimal in the combination group(63.0%vs 49.5%,P=0.046).No adverse events related to the drugs were *** Rebamipide/nizatidine combination is effective in treatment of erosive gastritis.

关键词： Gastritis Erosive gastritis Combination therapy Rebamipide Nizatidine