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Effect of gamma knife radiosurgery in the central nervous system lymphoma

中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： Beong Ik Hur Dong Wan Kang Won Ho Cho Seung Heon Cha chang hwa choi Byung Kwan choi Department of Neurosurgery Pusan National University Hospital

＜正＞Purposes:The secondary,independent verification of Leksell Gamma Knife treatment planning system（LGP） is extremely important in order to minimize the risk of treatment errors.

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Effect of gamma knife radiosurgery in the central nervous sy...

Patterns and determinants of plant richness by elevation in a mountain ecosystem in South Korea: area, mid-domain effect,climate and productivity

中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： Won Ho Cho Su Heon Lee Beong Ik Hur Seung Heon Cha chang hwa choi Department of Neurosurgery Pusan National University Hospital and School of Medicine Pusan National University BusanRepublic of Korea

＜正＞＜Introduction＞ Although there has been no established treatment protocol for central nervous system lymphoma （CNSL）,high dose methotrexatae therapy with or without external beam radiotherapy（EBRT） is gener...

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Journal of Forestry Research 2015年第4期26卷 905-917页

作者： chang-Bae Lee Jung-hwa Chun Korea Green Promotion Agency 121 DunsanbukroSeoguDaejeon 302-831Republic of Korea Division of Forest Ecology Korea Forest Research Institute57 HoegiroDongdaemunguSeoul 130-712Republic of Korea

We examined patterns of plant species richness on an elevation gradient and evaluated the effects of cli- matic variables including mean annual temperature and precipitation, area, the mid-domain effect and productivity on species richness along two transects on Mt. Seorak, South Korea. A total of 235 plant species of 72 families and 161 genera were recorded from 130 plots along the two transects. Two different patterns, monotonic decline and a unimodal shape, were observed for woody plants with the change in elevation along the two transects, whereas multimodal patterns were observed for all plant species considered together and for herbaceous plants. Area and productivity showed significant relationships with total plant richness. Climatic variables were better predictors than other variables for variation by elevation in woody plant richness, whereas productivity was a more important variable for herbaceous plant richness. Although area was an important variable for predicting species richness pat- terns, the effects differed by transect and plant group. No empirical evidence was linked to the mid-domain *** elevational patterns may characterize different groups in the same taxon and there might be fundamental differences in the mechanisms underlying these richness patterns.

关键词： Area Climatic variables Elevationalpatterns Plant richness Productivity

Diversity patterns and phylogenetic structure of vascular plants along elevational gradients in a mountain ecosystem, South Korea

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Journal of Mountain Science 2018年第2期15卷 280-295页

作者： CHUN Jung-hwa LEE chang-Bae Division of Forest Ecology National Institute of Forest Science Global Resources Division Korea Forestry Promotion Institute

Recently, a phylogenetic diversity and community structure analysis as complementary to species-centric approaches in biodiversity studies provides new insights into the processes of community assembly. In this study, we analyzed species and phylogenetic diversity and community structures for woody and herbaceous plants along two elevational transects on Mt. Baekhwa, South Korea. The species richness and phylogenetic diversity of woody plants showed monotonic declining patterns with increasing elevation along all transects, whereas herbaceous plants showed different patterns, such as no relationship and a reversed unimodal pattern, between the study transects. The main drivers of these patterns were climate and habitat variables for woody and herbaceous plants, respectively. In addition, the phylogenetic community structure primarily showed phylogenetic clustering regulated by deterministic processes, especially environmental filtering, such as climate or habitat factors, along the two transects, although herbaceous plants along a transect depicted phylogenetic randomness as a result of a neutral process. Our findings suggest that deterministic and neutral processes may simultaneously control the community structures along small-scale elevational gradients such as local transects, although the deterministic process may be the predominant type.

关键词： Community structure Deterministicprocess Elevational gradient Neutral process Phylogenetic diversity Species richness

Ventral hernia after high-intensity focused ultrasound ablation for uterine fibroids treatment:A case report

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World Journal of Clinical Cases 2022年第30期10卷 11204-11209页

作者： Jung-Woo Park hwa Yeon choi Department of Obstetrics and Gynecology Dong-A University College of MedicineBusan 49201South Korea

BACKGROUND High-intensity focused ultrasound(HIFU) ablation is a minimally invasive approach in gynecology that is used to manage uterine *** this procedure is safe and effective,adverse outcomes are becoming a major *** SUMMARY We present a case of ventral hernia that occurred as a rare and delayed complication of HIFU ablation for uterine fibroids *** patient came to the hospital with abdominal bloating that occurred 6 mo after ultrasound-guided HIFU ablation for managing uterine *** ventral hernia,which occurred due to atrophied muscle layers following the procedure,was confirmed by imaging studies and intraoperative *** required a hernia repair with mesh and hysterectomy for definitive treatment of uterine *** High-intensity ultrasound ablation should be performed only on appropriate *** should be educated about potential complications of the procedure and the possibility of subsequent ***-procedural long-term follow-up for detecting delayed adverse effects is important.

关键词： Uterine fibroids High-intensity focused ultrasound ablation Conservative treatment Ventral hernia Complication Case report

Population trend and spatio-temporal distribution of Greater White-fronted(Anser albifrons)and Bean Geese(Anser fabalis)in Korea

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Avian Research 2024年第4期15卷 458-465页

作者： Eun-Jeong Kim Wee-Heang Hur hwa-Jung Kim Yu-Seong choi Dongwon Kim Who-Seung Lee Sejeong Han Hyerin Joo chang-Yong choi Department of Agriculture Forestryand BioresourcesSeoul National UniversitySeoul08826Republic of Korea Research Institute of Agriculture and Life Science Seoul National UniversitySeoul08826Republic of Korea National Migratory Birds Center National Institute of Biological ResourcesIncheon22689Republic of Korea Division for Natural Environment Korea Environment InstituteSejong30147Republic of Korea

Geese have undergone significant changes in their distribution and population size due to human-induced *** improve our understanding of the two main geese populations in East Asia—Greater White-fronted(Anser albifrons;GWFG)and Bean Geese(Anser fabalis sensu lato;BEAG),which includes the Tundra ***(TDBG)and Taiga Bean Geese ***(TGBG),this study estimated their long-and short-term trends and the migration strategies based on their distribution during the migratory and wintering seasons,using nationwide census data collected over 24 years in South *** TRIM(TRends and Indices for Monitoring data)analysis supported a robust long-term population increase since 1999,recently stabilizing around 150,000 individuals in GWFG and 100,000 in TDBG,*** TGBG stabilized at around 7000 with no significant change of population over *** shorter-term trends within a season suggested that wintering populations of GWFG and TDBG in China might stop over in Korea in their autumn migration before their sea-crossing,evidenced by the large congregation near the Yellow Sea coast followed by a gradual *** contrast to autumn,there was no similar peak in spring migration,suggesting the potential for elliptical migration of some populations around the Yellow *** findings indicate a growing East Asian population and imply one of the migration strategies of the Greater White-fronted and Tundra Bean *** collaborating with recent tracking data,long-term monitoring efforts could offer more detailed insights into population trends and migration strategies,thereby contributing to the effective management and conservation of goose species in East Asia.

关键词： Bean Goose Anser fabalis East Asia Greater White-fronted Goose Anser albifrons Long-term monitoring Spatiotemporal distribution Non-breeding

DIRECT NUMERICAL SIMULATIONS OF THE DYNAMICS OF PARTICLES WITH ARBITRARY SHAPES IN SHEAR FLOWS

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Journal of Hydrodynamics 2010年第4期22卷 456-465页

作者： choi Choeng Ryul KIM chang Nyung Department of Mechanical Engineering Kyung Hee University College of Engineering Kyung Hee University Industrial Liaison Research Institute Kyung Hee University

A fluid-structure interaction method based on the arbitrary Lagrangian-Eulerian method and a dynamic mesh method was developed to simulate the dynamics of a rigid particle in shear *** the method,the governing equations for the fluid flow and particle motion were sequentially solved in a two-way coupling *** mesh system was deformed or re-meshed by the dynamic mesh *** method was employed to simulate the dynamics of a single particle suspended in a flow channel and the dynamics of the particle were *** simulation results show that the angular velocity is not only a function of the inclination angle,is but also influenced by the aspect ratio yielding a hysteresis,while the angular velocity obtained from the Keller-Scalak model is a function only of the inclination angle and does not show a *** present simulations clearly demonstrate that the Fluid-Structure Interaction（FSI） module is very stable,accurate and robust.

关键词： particle suspension Fluid-Structure Interaction (FSI) fluid-particle interaction particulate flow

Low skeletal muscle mass is associated with non-alcoholic fatty liver disease in Korean adults： the Fifth Korea National Health and Nutrition Examination Survey

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Hepatobiliary & Pancreatic Diseases International 2016年第1期15卷 39-47页

作者： hee yeon kim chang wook kim chung-hwa park jong young choi kyungdo han anwar t merchant yong-moon park division of hepatology department of internal medicinecollege of medicinethe catholic university of korea222Banpo-daeroSeocho-guSeou1 06591Republic of Korea department of biostatistics college of medicinethe catholic university of korea222Banpo-daeroSeocho-guSeou1 06591Republic of Korea department of epidemiology and biostatistics arnold school of public healthuniversity of south carolinaColumbiaSC 29208USA epidemiology branch national institute of environmental health sciencesnational institutes of healthdepartment of health and human servicesResearch Triangle ParkNC 27709USA

BACKGROUND： Sarcopenia and non-alcoholic fatty liver dis- ease （NAFLD） share similar pathophysiological mechanisms, and the relationship between sarcopenia and NAFLD has been recently investigated. The study investigated whether low skel- etal muscle mass is differentially associated with NAFLD by gender in Korean adults. METHODS： We conducted a cross-sectional analysis of the data from the Fifth Korea National Health and Nutrition Examination Survey. The skeletal muscle index （SMI） was obtained by the appendicular skeletal muscle mass divided by the weight. NAFLD was defined as a fatty liver index （FLI）〉60 in the absence of other chronic liver disease. RESULTS： Among the included subjects, 18.3% （SE： 1.4%） in men and 7.0% （SE： 0.7%） in women were classified as having FLI-defined NAFLD. Most of the risk factors for FLI-defined NAFLD showed a significant negative correlation with the SMI in both genders. Multiple logistic regression analysis showed that low SMI was associated with FLI-defined NAFLD, inde- pendent of other metabolic and lifestyle parameters in both genders [males： odds ratio （OR）=1.35; 95% confidence inter- val （CI）： 1.17-1.54; females： OR=1.36; 95% CI： 1.18-1.55]. The magnitude of the association between FLI-defined NAFLD and low SMI was higher in middle aged to elderly males （OR-1.50; 95% CI： 1.22-1.84） than in males less than 45 years of age （OR=1.25; 95% CI： 1.02-1.52） and in premenopausal females （OR=l.50; 95% CI： 1.12-2.03） than in postmenopausal females （OR-1.36; 95% CI： 1.20-1.54）.CONCLUSIONS： Low SMI is associated with the risk of FLI- defined NAFLD independent of other well-known metabolic risk factors in both genders. This association may differ ac- cording to age group or menopausal status. Further studies are warranted to confirm this relationship.

关键词： Korea National Health and Nutrition Examination Survey non-alcoholic fatty liver disease sarcopenia skeletal muscle

Fragile histidine triad gene alterations are not essential for hepatocellular carcinoma development in South Korea

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World Journal of Gastroenterology 2008年第22期14卷 3526-3533页

作者： chang Woo Nam Jung Woo Shin Neung hwa Park Department of Surgery University of Ulsan College of Medicine Biomedical Research Center Ulsan University Hospital Ulsan 682-714 South Korea Internal Medicine University of Ulsan College of Medicine Biomedical Research Center Ulsan University Hospital Ulsan 682-714 South Korea

AIM: To establish the role of FHIT in the pathogenesis hepatocellular carcinoma (HCC). METHODS: We examined genomic alterations, as well as, mRNA and protein expression patterns from the FHIT gene, in 48 surgically resected hepatocellular carcinoma (HCC) tissues. Additionally, p53 mutations were analyzed. RESULTS: Aberrant FHIT transcripts were detected in 11 of 48 surrounding non-tumor liver tissues and 27 of 48 HCC samples (22.9% vs 56.3%, P = 0.002). No point mutations were identified within the open reading frame region of FHIT. Loss of heterozygosity (LOH) of the FHIT locus was detected in 4 of 42 informative cases for D3S1300, and 3 of 29 informative cases for D3S1313. Reduced expression of FHIT protein (Fhit) was observed in 8 (16.7%) of 48 HCC samples, with complete loss of Fhit in only 1 case. There were no associations with abnormal transcripts, LOH, and Fhit expression. p53 mutations were identified in 9 of the 48 HCC cases. However, none of the cases displayed a G to T transversion at p53 codon 249. CONCLUSION: Aberrant FHIT transcripts were more common in HCC tissues as compared to non-cancerous liver tissues. However, Fhit expression was lost or reduced in a minor fraction of HCC tissues, while it was strongly expressed in non-cancerous liver ***, our study suggests that FHIT plays a role in relatively few HCC cases in South Korea.

关键词： Fragile histidine triad Aberrant transcripts Microsatellite instability Protein expression Hepatocellular carcinoma