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Polymyxin B hemoperfusion as a feasible therapy after source control in abdominal septic shock

World Journal of Gastrointestinal Surgery 2019年第12期11卷 422-432页

作者： Jin Joo kim Young Jun Park ki Yoon moon Jin Hyeong Park Yong ki Jeong Eun Young kim Division of Trauma and Surgical Critical Care Department of Surgery Seoul St. Mary’s Hospital College of Medicine The Catholic University of Korea

BACKGROUND Polymyxin B hemoperfusion(PMX-HP)has been used as a treatment for intraabdominal septic shock by absorbing and removing endotoxins of gram-negative *** To investigate the clinical efficacy of PMX-HP in patients with gram-negative septic shock who underwent abdominal *** From January 2012 to December 2018,patients who had septic shock secondary to peritonitis were *** were classified into PMX-HP treated and control groups based on postopreative intervention using *** clinical outcomes were compared using 1:1 propensity score matching methods to balance the overall distribution between the two *** After propensity score matching,40 patients were analyzed(20 patients in the PMX group and 20 patients in the control group).The scores of total Sequential Organ Failure Assessment(SOFA)score,renal SOFA and coagulation SOFA were significantly improved in the PMX group but not in the control group.(from 11.2±5.8 to 4.7±3.5 in PMX group vs 10.0±4.0 to 8.7±7.3 in control group,P=0.047 from 2.6±1.0 to 0.7±1.0 in PMX group vs 2.6±1.5 to 2.8±1.6 in control group,P=0.000,from 1.6±1.5 to 1.3±1.3 in PMX group vs 1.2±1.2 to 2.8±1.8 in control group,P=0.014,respectively).Further,the length of intensive care unit(ICU)stay was significantly shorter in PMX ***,no statistically significant difference was found in ICU mortality(50%in PMX group vs 50%in control group).CONCLUSION PMX-HP is a feasible adjunct treatment for peritonitis in ICU patients with peritonitis for improved organ impairment and to stabilize *** would be helpful to enhance clinical outcomes especially in patients with complete elimination of the source of gram-negative bacilli infection by surgical procedure accompanied with conventional treatment of sepsis.

关键词： Intraabdominal septic shock Panperitonitis Polymyxin B hemoperfusion Sepsis Toraymyxin

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日据时期朝鲜与台湾地区公医制度比较研究

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台湾历史研究 2024年第1期 9-32页

作者： [韩]文明基韩国国民大学韩国历史学系

为了填补医疗卫生之空白而实行的台湾地区公医制度,1913年在朝鲜同样实行了。两地的制度本身很相似,不过制度的实施效果却相当不一样。首先,台湾地区公医每个月要提出公医报告,但朝鲜公医没有这种义务,这种差异造成两地医疗卫生统计水... 详细信息

为了填补医疗卫生之空白而实行的台湾地区公医制度,1913年在朝鲜同样实行了。两地的制度本身很相似,不过制度的实施效果却相当不一样。首先,台湾地区公医每个月要提出公医报告,但朝鲜公医没有这种义务,这种差异造成两地医疗卫生统计水准的显著差距。其次,台湾地区公医组织公医会,相互交换有关医疗的资讯,但朝鲜公医没有类似组织。再次,台湾地区公医跟警察合作紧密,而在朝鲜没有公医和警察之间的紧密合作。而且台湾地区公医分布密度比朝鲜高,这一点影响到两地民众利用医院的频度和传染病的防治。相关史实显示,日据时期朝鲜的公共医疗卫生网络不如台湾地区组织紧密与有效。

关键词：公医制度日据时期台湾地区朝鲜医疗卫生

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Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: A retrospective cohort study

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World Journal of Gastroenterology 2011年第35期17卷 4031-4037页

作者： moon-Chan kim chang-Sup kim Tae-Heum Chung Hyoung-Ouk Park Cheol-In Yoo Department of Family Medicine Ulsan University Hospital University of Ulsan College of Medicine Ulsan 682-714 South Korea Department of Occupational and Environmental Medicine Ulsan University Hospital

AIM: To investigate relationships between colorectal adenoma incidence, metabolic syndrome (MS) components and lifestyle factors. METHODS: We conducted a retrospective cohort study using data from individuals who had multiple sigmoidoscopies for colon cancer at the Health Promotion Center of Ulsan University Hospital in Korea from 1998 to 2007. RESULTS: By multivariate analysis, the incidence of distal colon adenoma was increased by more than 1.76 times in individuals with at least one component of MS compared to those without a component of MS. After adjustment for age, gender, smoking, drinking, and physical exercise, only high body mass index (BMI) was significantly associated with the incidence of distal colon adenoma (Hazard ratio 1.66, 95% confidence interval 1.05-2.62). CONCLUSION: Our results suggest that high BMI may increase the risk of colorectal adenoma in Korean adults.

关键词： Body mass index Distal colon adenoma Korea Lifestyle risk factor Metabolic syndrome

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Prediction of nephrotoxicity induced by cisplatin combination chemotherapy in gastric cancer patients

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World Journal of Gastroenterology 2011年第30期17卷 3510-3517页

作者： Hyung Hwan moon Kyung Won Seo ki Young Yoon Yeon Myung Shin Kyung Hyun Choi Sang Ho Lee Department of Surgery Kosin University College of Medicine602-703 BusanSouth Korea

AIM:To evaluate the treatment options for nephrotoxicity due to cisplatin combination ***:We retrospectively reviewed patients who had received cisplatin combination chemotherapy for gastric cancer between January 2002 and December *** investigated patients who had shown acute renal failure(ARF),and examined their clinical characteristics,laboratory data,use of preventive measures,treatment cycles,the amount of cisplatin administered,recovery period,subsequent treatments,and renal status between the recovered and unrecovered ***:Forty-one of the 552 patients had serum creatinine(SCR)levels greater than 1.5 mg/*** found that pre-ARF SCR,ARF SCR,and ARF glomerular filtration rates were significantly associated with renal status postARF between the two groups(P=0.008,0.026,0.026,respectively).On the receiver operating characteristic curve of these values,a 1.75 mg/dL ARF SCR value had 87.5%sensitivity and 84.8%specificity(P=0.011).CONCLUSION:Cessation or reduction of chemotherapy should be considered for patients who have an elevation of SCR levels during cisplatin combination chemotherapy.

关键词： Acute renal failure Cisplatin Drug toxicities Nephrotoxicity

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Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique

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Asian Journal of Andrology 2018年第1期20卷 80-84页

作者： Dae Yul Yang Kyungtae Ko Seong Ho Lee Du Geon moon Jong Wook kim Won ki Lee Department of Urology College of Medicine Hallym University Chuncheon Korea Department of Urology College of Medicine Korea University Seoul Korea.

There is no safe and effective standard method for glans penis augmentation. Furthermore, there has been scant research on glans penis augmentation due to a poor understanding of glans anatomy, technical difficulty, and a lack of suitable substances for augmentation. Cross-linked dextran gel is a newly developed filler for soft-tissue augmentation. We evaluated the efficacy and safety of using a novel technique to inject cross-linked dextran gel for glans penis augmentation during a 24-week follow-up study. This prospective, single-arm, multicenter study enrolled twenty healthy adult men who underwent glans penis augmentation between June and August 2013. Cross-linked dextran gel was injected into the glans penis using a simple and easy technique. The sizes of the glans penis and individual satisfaction were assessed. Any adverse event was also reported. A total of 18 individuals were analyzed; two of them were lost to follow-up. The mean procedure time and injected volume were about 30 rain and 6.6 ＋- 0.9 ml, respectively. The mean surface areas of the glans at baseline and 24 weeks were 20.0 _＋ 3.5 cm2 and 33.6 -＋ 5.4 cm2, respectively, representing a mean increase of 68.7% _＋ 14.0% （P 〈 0.001）. Sixteen individuals （88.9%） were satisfied with the outcomes, and none were dissatisfied. There were no serious adverse events during the study. Cross-linked dextran gel injection for glans penis augmentation was easy and showed a significant augmentative effect on the glans penis, good durability, and was well tolerated without serious adverse events. Therefore, cross-linked dextran gel injection may be an effective, new technique for glans penis augmentation.

关键词： cosmetic technique dermal fillers dextran glans penis

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Weapon effectiveness and the shapes of damage functions

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Defence Technology（防务技术） 2021年第2期17卷 617-632页

作者： Sei-Hoon moon th R&D Institute Agency for Defense DevelopmentYusungDaejeon305-152Republic of Korea Department of Mechanical and Aerospace Engineering Naval Postgraduate School MontereyCA93940USA

This paper provides a review of methods of assessing a fragmentation weapon’s effectiveness against a point target or an area target with keeping the focus on the necessity of using the Carleton damage function with the correct shape ***,cookie-cutter damage functions are redefined to preserve the shape factor of and to have the same lethal area as the corresponding Carleton damage ***,closed-form solutions of the effectiveness methods are obtained by using those cookie-cutter damage functions and the Carleton damage ***,the closed-form solutions are applied to calculate the probability of damaging a point target and the expected fractional damage to an area target for several attack scenarios by using cookie-cutter damage functions and the Carleton damage functions with different shape *** comparison of the calculation results shows that using cookie-cutter damage functions or the Carleton damage function with a wrong shape factor results in quite significant differences from using the original Carleton damage function with a correct shape factor when weapon’s delivery error deviations are less than or comparable to the lengths of the lethal area and the aim point is far from a *** effectiveness methods improved in this paper will be useful for mission planning utilizing the precision-guided munitions in circumstances where the collateral damage should be reduced.

关键词： Weapon effectiveness Point target Area target Cookie-cutter damage function Carleton damage function

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FOR A SHARED FUTURE

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Beijing Review 2021年第15期64卷 16-18页

作者： Ban ki-moon 不详

The shared future of Asia and the world can only be secured by the close and win-win cooperation of all This year marks the 20 th anniversary of the Boao Forum for Asia(BFA). This is a moment of significance, with muc... 详细信息

关键词： anniversary cooperation marks

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Ischemic colitis associated with intestinal vasculitis: Histological proof in systemic lupus erythematosus

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World Journal of Gastroenterology 2008年第22期14卷 3591-3593页

作者： Jeong Rok Lee chang Nyol Paik Jin Dong kim Woo Chul Chung Kang-moon Lee Department of Internal Medicine College of Medicine The Catholic University of Korea St. Vincent's Hospital Suwon Si Paldal-gu Gyeonggi-Do 442-723 South Korea

I schemic colitis is an uncommon complication in patients with systemic lupus erythematosus (SLE). In previously reported cases of colitis caused by SLE, intestinal vasculitis is implicated as the causative process, but is rarely confirmed histologically. We described a case of a 32-year-old man with increased activity of SLE, who presented with hematochezia and abdominal pain due to ischemic colitis with small vessel vasculitis which was proven by sigmoidoscopic biopsy. The clinical course of the patient was improved after steroid and conservative management.

关键词： Systemic lupus erythematosus Ischemic colitis Vasculitis

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Development of a low-cost GPS/INS integrated system for tractor automatic navigation

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International Journal of Agricultural and Biological Engineering 2017年第2期10卷 123-131页

作者： Xiongzhe Han Hak-Jin kim Chan Woo Jeon Hee chang moon Jung Hun kim Dept.of Biosystems and Biomaterials Engineering College of Agriculture and Life SciencesSeoul National University.Seoul 08826Republic of Korea Unmanned Solutions Co. Seoul 06643Republic of Korea R&D Institute Tong Yang Moolsan Co.LTDChungcheongnam-do 32530Republic of Korea

The use of low-cost single GPS receivers and inertial sensors for auto-guidance applications has been limited by their reduced accuracy and signal drift over time compared to real-time kinematic(RTK)differential GPS units and fiber-optic gyroscope(FOG)*** this study,a prototype low-cost GPS/INS integrated system consisting of a triangle-shaped array of three Garmin 19x GPS receivers and an Xsens inertial measurement unit(IMU)to improve the accuracy of position and heading angle measured with a single GPS receiver was developed.A triangular algorithm that uses data collected from the three single GPSs mounted on the angular points of a triangular frame was designed.A sensor fusion algorithm based on the Kalman filter combining the GPS and IMU data was developed by integrating position data and heading angles of a triangular array of GPS *** optimized values of two noise covariance matrixes(Q and R)for the Kalman filtering were determined using the Central Composite Design(CCD)*** compared to the use of a single Garmin GPS receiver,use of the developed GPS/INS system showed improved accuracy performance in terms of both position and heading angle,with reductions in root mean square errors(RMSEs)from 2.7 m to 0.64 m for position and from 8.9ºto 2.1ºfor heading *** accuracy improvements show new potential for agricultural auto-guidance applications.

关键词： global positioning system tractor automatic navigation sensor fusion Kalman filter inertial sensor heading angle

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A DECADE’S DIALOGUE

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Beijing Review 2016年第28期59卷 14-15页

作者： Ban ki-moon

Editor＇s Note： UN Secretary General Ban ki-moon visited China on July 6-10, his 10th trip to the country since assuming office on January I, 2007. Known for his unwavering determination to bring nations together, Ban has always taken a hands-on approach to the thorniest issues. His tenure ends this year after leading the UN for a decade. During the Beijing leg of Ban＇s five-day visit, Beijing Review President Li Yafang and reporter Liu Yunyun sat down with the secretary general to talk about his experience and his vision for the world. An edited excerpt of the interview follows：

关键词： ECAD 联合国秘书长对话北京站 Ban 编者

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