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Neural Regeneration Research 2017年第12期12卷 2021-2024页

作者： Sung Ho Jang Jun Lee Sang Seok yeo Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Namku Daegu Republic of Korea Department of Neurology College of Medicine Yeungnam University Namku Daegu Republic of Korea Department of Physical Therapy College of Health Sciences Dankook University Chungnam Republic of Korea

Many studies using diffusion tensor tractography（DTT） have demonstrated that injury of the spinothalamic tract（STT） is the pathogenetic mechanism of central post-stroke pain（CPSP） in intracerebral hemorrhage; however, there is no DTT study reporting the pathogenetic mechanism of CPSP in cerebral infarction. In this study, we investigated injury of the STT in patients with CPSP following cerebral infarction, using DTT. Five patients with CPSP following cerebral infarction and eight age-and sex-matched healthy control subjects were recruited for this study. STT was examined using DTT. Among DTT parameters of the affected STT, fractional anisotropy and tract volume were decreased by more than two standard deviations in two patients（patients 1 and 2） and three patients（patients 3, 4, and 5）, respectively, compared with those of the control subjects, while mean diffusivity value was increased by more than two standard deviations in one patient（patient 2）. Regarding DTT configuration, all affected STTs passed through adjacent part of the infarct and three STTs showed narrowing. These findings suggest that injury of the STT might be a pathogenetic etiology of CPSP in patients with cerebral infarction.

关键词： nerve regeneration central post-stroke pain cerebral infarction spinothalamic tract diffusion tensorimaging neural regeneration

Central bank digital currency,loan supply,and bank failure risk:a microeconomic approach

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Financial Innovation 2021年第1期7卷 1945-1966页

作者： Jooyong Jun Eunjung yeo Department of Economics Dongguk UniversitySeoul 04620Korea School of Business Administration College of Business and EconomicsChung-Ang UniversitySeoul 06974Korea

Central bank digital currencies(CBDCs),which are legal tenders in digital form,are expected to reduce currency issuance and circulation costs and broaden the scope of monetary *** addition,these currencies may also reduce consumers’need for conventional demand deposits,which,in turn,increases banks’loan provision costs because deposits require higher rates of *** use a microeconomic banking model to investigate the effects of introducing an economy-wide,account-type CBDC on a bank’s loan supply and its failure *** that a CBDC is expected to lower the cost of liquidity circulation and become a strong substitute for demand deposits,both the loan supply and the bank failure risk *** increases are countered by subsequent increases in the rates of return on term deposits and loans,which,in turn,reduce the loan supply and thus bank failure *** offsetting forces lead to no significant change in banking,as long as the rate of return on loans is below a certain ***,once the rate is above the threshold,bank failure risk increases,thereby undermining banking *** problem is more pronounced when the degree of pass-through of funding costs to the loan rate is high and the profitability of a successful project is *** results imply that central banks wishing to introduce an economy-wide,account-type CBDC should first monitor yields on bank loans and consider policy measures that induce banks to maintain adequate liquidity reserve levels.

关键词： Central bank digital currency Bank failure risk Loan supply

Value of quality of life analysis in liver cancer: A clinician's perspective

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World Journal of Hepatology 2017年第20期9卷 867-883页

作者： Leung Li Winnie yeo Department of Clinical Oncology Prince of Wales HospitalFaculty of Medicinethe Chinese University of Hong KongChina

Health related quality of life(HRQOL) is increasingly recognized as an important clinical parameter and research endpoint in patients with hepatocellular carcinoma(HCC). HRQOL in HCC patients is multifaceted and affected by medical factor which encompasses HCC and its complications, oncological and palliative treatment for HCC, underlying liver disease, as well as the psychological, social or spiritual reaction to the disease. Many patients presented late with advanced disease and limited survival, plagued with multiple symptoms, rendering QOL a very important aspect in their general well being. Various instruments have been developed and validated to measure and report HRQOL in HCC patients, these included general HRQOL instruments, e.g., Short form(SF)-36, SF-12, Euro Qo L-5D, World Health Organization Quality of Life Assessment 100(WHOQOL-100), World Health Organization Quality of Life Assessment abbreviated version; general cancer HRQOL instruments, e.g., the European Organisation for Research and Treatment of Cancer(EORTC) QLQ-C30, Functional Assessment of Cancer Therapy(FACT)-General, Spitzer Quality of Life Index; and liver-cancer specific HRQOL instruments, e.g., EORTC QLQ-HCC18, FACT-Hepatobiliary(FACT-Hep), FACT-Hep Symptom Index, Trial Outcome Index. Important utilization of HRQOL in HCC patients included description of symptomatology and HRQOL of patients, treatment endpoint in clinical trial, prognostication of survival, benchmarking of palliative care service and health care valuation. In this review, difficulties regarding the use of HRQOL data in research and clinical practice, including choosing a suitable instrument, problems of missing data, data interpretation, analysis and presentation are examined. Potential solutions are also discussed.

关键词： Hepatocellular carcinoma Health related quality of life Palliative care Prognosis Survival The European Organisation for Research and Treatment of Cancer QLQ-C30 QLQ-HCC18 Index score Functional Assessment of Cancer Therapy EQ-5D Spitzer Short form 36 FHSI-8 World Health Organization Quality of Life Assessment

Apocrine hidrocystoma of the conjunctiva

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International Journal of Ophthalmology(English edition) 2012年第2期5卷 247-248页

作者： Boyun Kim Nam yeo Kang Department of Ophthalmology Bucheon St. Mary's Hospital College of Medicine The Catholic University of Korea Bucheon Kyunggi-do 420-717 Korea

Dear Sir, I am Dr. Boyun Kim, form the Department of Ophthalmology, Bucheon St. Mary’s Hospital, Bucheon, Korea. I write to present a case report of apocrine hidrocystoma on temporal bulbar conjunctiva. Apocrine hidrocystoma (AH) is a benign cutaneous cystic nodule arising from apocrine glands of Moll [1]. This lesion usually occurs on eyelids and canthus [1,2], ears, chest, shoulders in adults but its occurrence in conjunctiva [3] is

关键词： Figure Apocrine hidrocystoma of the conjunctiva

Injury of thalamocortical connection between the mediodorsal nucleus of the thalamus and the orbitofrontal cortex in a patient with traumatic brain injury

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Neural Regeneration Research 2018年第6期13卷 1118-1120页

作者： Sung Ho Jang Seong Ho Kim Sang Seok yeo Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Neurosurgery College of Medicine Yeungnam University Department of Physical Therapy College of Health Sciences Dankook University

The prefrontal cortex（PFC）is responsible for personality expression and various cognitive functions,including working memory,recognition memory,decision making,attention,and motivation（Frey and Petrides,2000,2002;M... 详细信息

关键词： TBI OFC DTI MD

The role of mitochondria in redox signaling of muscle homeostasis

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Journal of Sport and Health Science 2020年第5期9卷 386-393页

作者： Li Li Ji dongwook yeo Chounghun Kang Tianou Zhang The Laboratory of Physiological Hygiene and Exercise Science University of Minnesota Twin CitiesMinneapolisMN 55455USA Department of Orthopedic Surgery Mayo ClinicRochesterMN 55905USA Department of Physical Education Inha UniversityIncheon 22212Republic of Korea Department of Kinesiology Health and NutritionUniversity of Texas at San AntonioSan AntonioTX 78249USA

In the past,contraction-induced production of reactive oxygen species(ROS)has been implicated in oxidative stress to skeletal *** research advances,clear evidence has revealed a more complete role of ROS under both physiologic and pathologic *** to the role of ROS is the redox signaling pathways that control exercise-induced major physiologic and cellular responses and adaptations,such as mitochondrial biogenesis,mitophagy,mitochondrial morphologic dynamics,antioxidant defense,and *** current review focuses on how muscle contraction and immobilization may activate or inhibit redox signalings and their impact on muscle mitochondrial homeostasis and physiologic implications.

关键词： Antioxidant Exercise Peroxisome-proliferator-activated receptorγcoactivator 1-α Reactive oxygen species Redox signaling Skeletal muscle

Conventional processes and membrane technology for carbon dioxide removal from natural gas:A review

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Journal of Natural Gas Chemistry 2012年第3期21卷 282-298页

作者： Zee Ying yeo Thiam Leng Chew Abdul Rahman Mohamed Siang-Piao Chai Chemical Engineering Discipline School of EngineeringMonash University46150 Bandar SunwaySelangorMalaysia Faculty of Engineering and Green Technology(FEGT) Perak CampusUniversiti Tunku Abdul RahmanJalan UniversitiBandar Barat31900 KamparPerakMalaysia School of Chemical Engineering Engineering CampusUniversiti Sains MalaysiaSeri Ampangan14300 Nibong TebalPenangMalaysia

Membrane technology is becoming more important for CO,_ separation from natural gas in the new era due to its process simplicity, relative ease of operation and control, compact, and easy to scale up as compared with conventional processes. Conventional processes such as absorption and adsorption for CO2 separation from natural gas are generally more energy demanding and costly for both operation and maintenance. Polymeric membranes are the current commercial membranes used for CO2 separation from natural gas. However, polymeric membranes possess drawbacks such as low permeability and selectivity, plasticization at high temperatures, as well as insufficient thermal and chemical stability. The shortcomings of commercial polymeric membranes have motivated researchers to opt for other alternatives, especially inorganic membranes due to their higher thermal stability, good chemical resistance to solvents, high mechanical strength and long lifetime. Surface modifications can be utilized in inorganic membranes to further enhance the selectivity, permeability or catalytic activities of the membrane. This paper is to provide a comprehensive review on gas separation, comparing membrane technology with other conventional methods of recovering CO2 from natural gas, challenges of current commercial polymeric membranes and inorganic membranes for CO2 removal and membrane surface modification for improved selectivity.

关键词： membrane technology inorganic membrane CO2 separation natural gas: surface modification

环境生物有效性:耐药性诱导研究的潜在重要元素

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Science Bulletin 2022年第22期67卷 2269-2271页

作者： Han yeong Kaw 俞景马雪菁 Bee Geok yeo 朱利中王玮 Department of Environmental Science Zhejiang UniversityHangzhou 310058China Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control Hangzhou 310058China Laboratory of Organic Geochemistry(LOG) Tokyo University of Agriculture and TechnologyFuchu 183-8509Japan

Antimicrobial resistance(AMR)is unquestionably-one of the most severe,international public health crises that mankind faces now and in the next decades,with the latest data indicating global deaths quintuple over the past five years to claim nearly 5 million lives[1],which seems substantially underestimated the projected health impact(10 million deaths)and economic burden(US$100 trillion)of AMR by 2050[2].To counteract the burgeoning AMR crisis,the One Health initiative has called for international collective effort in improving human,animal and environmental health through integrated management of this interfacial *** which,the environmental dimension is often underrepresented,especially soil compartment as the origin,reservoir and transmission route for propagating antibiotic resistance genes(ARGs)in microbiota that exacerbate AMR[3].

关键词： collective reservoir resistance

Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice

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Translational Neurodegeneration 2019年第1期8卷 317-332页

作者： Hyeon Joo Ham Sang-Bae Han Jaesuk Yun In Jun yeo Young Wan Ham Se Hyun Kim Pil-Hoon Park dong-Young Choi Jin Tae Hong College of Pharmacy and Medical Research Center Chungbuk National UniversityOsongsaengmyeong 1-roOsong-eupHeungdeok-guCheongjuChungbuk 28160Republic of Korea Department of Chemistry Utah Valley University800 W University PkwyOremUT 84058USA INISTst Co. LTD767Sinsu-roSuji-guYongin-si 16827Gyeonggi-doRepublic of Korea College of Pharmacy Yeungnam University280 Daehak RoadGyeonsanGyeongbuk 38541Republic of Korea

Background:Neuroinflammation and accumulation ofβ-amyloid(Aβ)play a significant role in the onset and progression of Alzheimer’s disease(AD).Our previous study demonstrated that signal transducer and activator of transcription-3(STAT3)plays a major role in neuroinflammation and ***:In the present study,we investigated the inhibitory effect of bee venom phospholipase A2(bvPLA2)on memory deficiency in Tg2576 mice,which demonstrate genetic characteristics of AD and the mechanism of its action at the cellular and animal *** in vivo study,we examined the effect of bvPLA2 on improving memory by conducting several behavioral tests with the administration of bvPLA2(1 mg/kg)to Tg2576 *** in vitro study,we examined the effect of bvPLA2 on amyloidogenesis and neuroinflammation by treating bvPLA2 on LPSactivated BV2 ***:We found that bvPLA2 alleviated memory impairment in Tg2576 mice,as demonstrated in the behavioral tests assessing *** the bvPLA2-treated group,Aβ,amyloid precursor protein(APP),and β-secretase 1(BACE1)levels and β-secretase activity were significantly *** of pro-inflammatory cytokines and inflammation-related proteins decreased in the brain of bvPLA2-treated group,whereas anti-inflammatory cytokines *** addition,bvPLA2 reduced STAT3 phosphorylation in the brains of the bvPLA2-treated *** the cellular level,bvPLA2 inhibits production of nitric oxide,pro-inflammatory cytokines,and inflammation-related proteins including ***,bvPLA2 inhibits the production of Aβin cultured BV-2 *** from the docking experiment,pull-down assay,and the luciferase assay show that bvPLA2 directly binds STAT3 and,thus,regulates gene expression ***,when the STAT3 inhibitor and bvPLA2 were administered together,the anti-amyloidogenic and anti-inflammatory effects were further enhanced than when they were administered ***:These results suggest that bvPLA2 could r

关键词： Bee venom phospholipase A2 Alzheimer’s disease Amyloidogenesis Neuroinflammation STAT3

基于0.18-μm锗硅BiCMOS工艺的60 GHz匹配型高隔离小型化变压器巴伦

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红外与毫米波学报 2022年第1期41卷 299-304页

作者：张大为徐鑫李斌徐辉于洪喜李军马凯学 THANGARASU Bharatha Kumar yeo Kiat Seng 中国空间技术研究院西安分院微波技术研究所中国陕西西安710049 天津大学微电子学院中国天津300072 新加坡科技设计大学新加坡487372

介绍了一种工作在60 GHz频率的具有输出端口间高隔离和全端口匹配特性的小型化变压器巴伦芯片,该芯片采用0.18-μm锗硅BiCMOS工艺设计并加工。通过在60 GHz变压器巴伦的输出端口之间引入隔离电路,提高巴伦的隔离度性能并改善输出端口匹... 详细信息

介绍了一种工作在60 GHz频率的具有输出端口间高隔离和全端口匹配特性的小型化变压器巴伦芯片,该芯片采用0.18-μm锗硅BiCMOS工艺设计并加工。通过在60 GHz变压器巴伦的输出端口之间引入隔离电路,提高巴伦的隔离度性能并改善输出端口匹配性能;在此基础上,提出了一种基于左手材料传输线的隔离电路,能大大改善传统隔离电路中分布式传输线尺寸大的问题;为了进一步实现巴伦的小型化,在设计中采用了负载电容补偿技术,同时能改善变压器巴伦输入端口的匹配性能。设计的巴伦芯片经过电磁场仿真,其结果与在片测试结果有较高的一致性,验证了提出的设计方法,设计的巴伦芯片具有全端口匹配和输出端口间高隔离度的特性。基于实测结果,在60 GHz频率处,设计的巴伦芯片实现了超过25 dB的输出端口隔离度和优于18 dB的输出端口回波损耗,且占用尺寸极小,仅为0.022 mm^(2)。

关键词：变压器巴伦隔离电路 60 GHz 左手材料传输线