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黄芪超滤液的纳滤工艺及纳滤液干燥方法研究

中国新药杂志 2024年第7期33卷 722-729页

作者：万玲娟何红杰王博轩辕亮董建斌刘晓霞冯晓莉魏舒畅甘肃中医药大学甘肃省中药制药工艺工程研究中心兰州730000 兰州和盛堂制药股份有限公司兰州730000

目的:建立黄芪超滤液的纳滤浓缩工艺及纳滤液的干燥方法。方法:以黄芪甲苷、毛蕊异黄酮葡萄糖苷、毛蕊异黄酮、芒柄花苷、黄芪多糖、乙醇浸出物为评价指标,以滤过温度、操作压力、膜面错流速度为考察因素,采用AHP-熵权法的主客观组合赋... 详细信息

目的:建立黄芪超滤液的纳滤浓缩工艺及纳滤液的干燥方法。方法:以黄芪甲苷、毛蕊异黄酮葡萄糖苷、毛蕊异黄酮、芒柄花苷、黄芪多糖、乙醇浸出物为评价指标,以滤过温度、操作压力、膜面错流速度为考察因素,采用AHP-熵权法的主客观组合赋权和L_(9)(3~4)正交设计法,优选出黄芪超滤液的最佳纳滤工艺;比较冷冻干燥、真空干燥、常压干燥及微波干燥对纳滤液的影响,通过综合评分和指纹图谱联合使用,优选出纳滤浓缩液的最佳干燥方法。结果:黄芪超滤液的最佳纳滤工艺为压力0.16 MPa,温度40℃,错流速度4.5 m·s^(-1);纳滤液最佳干燥方法为真空干燥法。结论:本研究可为高品质黄芪提取物的工业化生产提供一种高效节能的技术。

关键词：纳滤真空干燥 AHP-熵权法指纹图谱

Failure mechanism and influencing factors of cement sheath integrity under alternating pressure

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Petroleum Science 2023年第4期20卷 2413-2427页

作者： Kuan-Hai Deng Nian-Tao Zhou Yuan-Hua Lin Yan-Xian Wu Jie Chen chang shu Peng-Fei Xie State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation(Southwest Petroleum University) ChengduSichuan610500China Engineering Technology Research Institute PetroChina Xinjiang Oilfield CompanyKaramayXinjiang834000China CNPC Xibu Drilling Engineering Company Limited UrumqiXinjiang830000China Engineering Technology Research Institute PetroChina Southwest Oil&Gas Field CompanyChengduSichuan610066China

The failure of cement sheath integrity can be easily caused by alternating pressure during large-scale multistage hydraulic fracturing in shale-gas *** elastic-plastic mechanical model of casing-cement sheath-formation(CSF)system under alternating pressure is established based on the Mohr-Coulomb criterion and thick-walled cylinder theory,and it has been solved by MATLAB programming combining global optimization algorithm with Global *** failure mechanism of cement sheath integrity is investigated,by which it can be seen that the formation of interface debonding is mainly related to the plastic strain accumulation,and there is a risk of interface debonding under alternating pressure,once the cement sheath enters plasticity whether in shallow or deep well *** matching relationship between the mechanical parameters(elastic modulus and Poisson's ratio)of cement sheath and its integrity failure under alternating pressure in whole well sections is studied,by which it has been found there is a“critical range”in the Poisson's ratio of cement *** the Poisson's ratio is below the“critical range”,there is a positive correlation between the yield internal pressure of cement sheath(SYP)and its elastic ***,when the Poisson's ratio is above the“critical range”,there is a negative *** elastic modulus of cement sheath is closely related to its Poisson's ratio,and restricts each *** and reasonable matching between mechanical parameters of cement sheath and CSF system under different working conditions can not only reduce the cost,but also protect the cement sheath integrity.

关键词： Casing-cement sheath-formation system Mechanical model Matching relationship Cement sheath integrity Critical range Mechanical parameters

自显影体外开窗、烟囱与Ⅳb型杂交技术在胸主动脉腔内修复术中重建左锁骨下动脉效果的对比研究

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中华普通外科杂志 2024年第9期39卷 662-666页

作者：翟浠烨舒畅张译丹范博文韩辉田川方坤罗明尧中国医学科学院北京协和医学院阜外医院血管外科中心、国家心血管病中心、心血管疾病国家重点实验室北京100037 中南大学湘雅二医院血管外科长沙410011 阜外华中心血管病医院血管外科郑州450046 云南阜外心血管病医院血管外科昆明650102

目的对比自显影体外开窗、烟囱与Ⅳb型杂交技术在胸主动脉腔内修复术中重建左锁骨下动脉的效果。方法回顾性分析中国医学科学院阜外医院2016年1月至2019年12月312例行胸主动脉腔内修复术并重建左锁骨下动脉血供患者的临床及随访资料。结... 详细信息

目的对比自显影体外开窗、烟囱与Ⅳb型杂交技术在胸主动脉腔内修复术中重建左锁骨下动脉的效果。方法回顾性分析中国医学科学院阜外医院2016年1月至2019年12月312例行胸主动脉腔内修复术并重建左锁骨下动脉血供患者的临床及随访资料。结果35例为Ⅳb型杂交血管搭桥组,93例为烟囱组,184例为体外开窗组。随访时间12~24个月。所有患者随访期间均未出现人工血管及支架闭塞,左锁骨下动脉血流通畅。19例患者在末次随访时存在内漏,三组间差异无统计学意义(P>0.05)。11例患者进行了再干预手术治疗,均为烟囱组及体外开窗组患者,但差异无统计学意义(P>0.05)。住院期间,28例患者出现并发症,其中搭桥组院内并发症发生率最高(P0.05)。结论体外开窗和烟囱技术重建左锁骨下动脉血流的安全性和疗效相似,对于左锁骨下动脉的血流重建效果确切,早期并发症低于Ⅳb型杂交技术,但内漏再干预率高。

关键词：主动脉疾病支架自显影体外开窗烟囱支架 Ⅳb型杂交左锁骨下动脉

Short-term results in canines of novel stent-graft design for chimney technique in TEVAR

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Journal of Interventional Medicine 2020年第3期3卷 128-131页

作者： Ming Li chang shu Benhao Xiao Dingxiao Liu Weichang Zhang Department of Vascular Surgery The Second Xiangya HospitalCentral South UniversityChangsha410011China Department of Vascular Surgery Fuwai HospitalChinese Academy of Medical SciencesBeijing100037China Lifetech Scientific Co.Ltd China

Introduction:Parallel stent-stent grafting is a major endovascular technique used to preserve the supra-aortic branches during thoracic endovascular aortic repair(TEVAR)of aortic pathologies involving the aortic *** short-and mid-term results of this technique are satisfactory;however,endoleak remains a major ***,here we designed a new chimney stent-graft to decrease the endoleak ***:To testify the feasibility and safety of the new chimney stent-graft system in a canine *** and methods:Six Labrador retrievers were ***-operative data were collected and all operations were performed under general *** main and chimney stent-grafts were implanted through the abdominal aorta and left subclavian artery approaches,*** digital subtraction angiography(DSA)was performed to confirm the immediate *** dogs were fed separately for 6 months and sacrificed after aortic *** thoracic aorta and the main and chimney stent-grafts were harvested for histopathologic ***:No complications were found in follow-up *** branch arteries were ***?ammatory responses were observed around the stent-grafts in 3 experimental animals,and slight hyperplasia was observed in the surrounding tissues compared with the normal *** was no mural thrombus in the stent,endothelial cells were noted on the inner surface of the stent,and thrombus was formed in the outer skirt and gutter *** histopathologic examinations revealed similar results to those of gross necropsy ***:This study demonstrated the feasibility and safety of the Longuette stent-graft and the first to report a revised stent-graft specific for chimney technique.

关键词： Thoracic endovascular aortic repair Chimney technique Canine model In vivo experiment Stent-graft

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定日镜场效率参数模型的研究

兰州文理学院学报（自然科学版） 2024年第5期38卷 30-36,53页

作者：解慧张建国李舒畅李腾飞程翔晋中学院数学系山西晋中030619 晋中学院物理系山西晋中030619 晋中学院信息技术与工程系山西晋中030619

针对定日镜场相关效率参数问题,根据几何光学知识,计算出定日镜场中太阳高度角和方位角、每个定日镜与地面的倾角.采用光线追踪法,通过阴影遮挡效率、余弦效率、大气透射率集热器截断效率和镜面反射率构建光学效率参数模型,建立定日镜... 详细信息

针对定日镜场相关效率参数问题,根据几何光学知识,计算出定日镜场中太阳高度角和方位角、每个定日镜与地面的倾角.采用光线追踪法,通过阴影遮挡效率、余弦效率、大气透射率集热器截断效率和镜面反射率构建光学效率参数模型,建立定日镜场的输出热功率的优化模型,在定日镜场达到额定功率的条件下,得出定日镜单位面积镜面平均输出热功率的优值.

关键词：光线追踪法定日镜场几何光学光学效率

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Long-term improvements in water conservation functions at Qilian Mountain National Park, northwest China

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Journal of Mountain Science 2023年第10期20卷 2885-2897页

作者： GAO Xiang HUANG Xing-xing chang shu-hang DANG Qian-wen WEN Rui-yang LO Kevin LI Jie YAN An College of Earth and Environmental Sciences Lanzhou UniversityLanzhou 730000China Department of Geography Hong Kong Baptist UniversityHong Kong 999077China

Water conservation is one of the most important ecosystem *** study uses the InVEST model to examine the water conservation function of the Qilian Mountain National Park(QMNP),an important water supply area in northwest *** analyzed the spatiotemporal water conservation patterns of QMNP from 1988 to *** showed that the water conservation capacity in QMNP has increased over the past 32 years,reaching a peak of 6.495×108 m3 in *** area with an increased water conservation capacity is 12 times larger than the area with a reduced *** also examined how climatic,land-use,vegetation coverage,and topographical factors influence water conservation *** found that precipitation is the main climatic factor in water *** water conservation function also varies with land-cover type,with forests having the highest capacity,followed by ***,topographical factors,including altitude and slope,also shape the spatial patterns of water conservation functions in QMNP.

关键词： Water conservation function Ecosystem services InVEST model Qilian Mountain National Park Northwest China

基于“精血俱耗致衰”探讨高龄复发性流产的证治思路

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湖南中医药大学学报 2024年第6期44卷 1079-1084页

作者：舒畅刘雁峰邓楠李影闫菲徐子涵金凡惠北京中医药大学北京100029 北京中医药大学东直门医院北京100700

复发性流产是临床常见的妊娠并发症,近年来伴随高龄孕产妇人数的增加,复发性流产发病率逐渐增加。从“精血俱耗致衰”的角度切入,通过探讨其理论内涵,提出高龄复发性流产的发生与精血虚衰关系密切;进一步总结高龄复发性流产患者病机以... 详细信息

复发性流产是临床常见的妊娠并发症,近年来伴随高龄孕产妇人数的增加,复发性流产发病率逐渐增加。从“精血俱耗致衰”的角度切入,通过探讨其理论内涵,提出高龄复发性流产的发生与精血虚衰关系密切;进一步总结高龄复发性流产患者病机以肾虚为本,以精血虚耗为主,同时可兼具血瘀、寒凝、气滞等病理因素,与心、肝、脾等多脏相关。治疗以益精养血为主,妊娠前补肾调肝、交通心肾,妊娠期健脾益肾、固摄胎元,从而减少复发性流产的发生。

关键词：精血俱耗复发性流产滑胎脏腑辨证生殖衰老

International Exchanges of Beijing Capital Agribusiness Group

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International Understanding 2015年第1期 38-41页

作者： shu chang

Beijing Capital Agribusiness Group(hereinafter referred to as CAG),previously known as Beijing Municipal State Farm Administration,is an industry leader of strong brand competitiveness with 133 thousand hectares of st... 详细信息

关键词： thousand leader owned hereinafter exchanges asset instructions seriously friendly subsidiary

Analysis of E-procurement Strategy of Aviation Enterprise with e-SCM

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International Journal of Plant Engineering and Management 2015年第4期20卷 213-224页

作者： chang Guang-shu Henan Aviation Economy Research Center Zhengzhou University of Aeronautics

The e-commerce has been more and more important for the procurement of material and parts in aviation enterprise. As a trend and hot-point of supply chain management, the electronic supply chain management should be utilized to achieve the rapid, healthy and orderly development of e-procurement. In this paper, the main reasons for applying e-SCM in the advanced experience both at home and abroad were firstly analyzed. Then, several revelations were proposed so as to promote the rapid development of e-procurement in aviation enterprise

关键词： e-procurement e-SCM supply chain aviation enterprise