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Synergistic Effect of Metal Nanoparticles on the Antimicrobial Activities of Antibiotics against Biorecycling Microbes

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Journal of Materials Science & Technology 2016年第6期32卷 524-532页

作者： chandni khurana Purnima Sharma O.E Pandey Bhupendra Chudasama Laboratory of Nanomedicine School of Physics and Materials ScienceThapar UniversityPatiala 147004India Department of Applied Sciences Chandigarh UniversityMohali 160055India Department ofBiotechnology Thapar UniversityPatiala 147004India

Biorecycling microbes, which have critical functionalities in natural cycles, are essential to sustain eco-system of the earth. Any alterations in these cycles caused by the mutations of microbes could be a potential threat to life on earth. Antibiotics leached from pharmaceutical waste, animal food and agribusiness prod- ucts are accumulating in the environment. Metal nanoparticles are also accumulating in environment because of their extensive use as biocidal agent in domestic products. Interaction of antibiotics and metal nanoparticles with eco-ffiendly microorganisms has a potential to alter the ecosystem of the earth. In this article, we have studied the antibacterial activities of silver and copper nanoparticles and their for- mulations with antibiotics, tetracycline, and kanamycin against biorecycling microbes, Bacillus subtilis and Pseudomonas fluorescens. Strong synergistic effect of metal nanoparticles on the antimicrobial ac- tivities of commercial antibiotics has been observed. Antimicrobial activity of tetracycline improves by 286%-346% and 0%-28% when being tested in the presence of 250 ppm of silver and copper nanoparticles, respectively. For kanamycin, the improvement is 154%-289% for silver and 3%-20% for copper nanoparticles. Irrespective of the antibiotics and tested organisms, synergy is more prominent for silver nanoparticles even at their minimum active concentration （100 ppm）. This study demonstrates that the combination of metal nanoparticles with antibiotics could be more fatal to ecosystem than either the metal nanoparticles or the antibiotics alone.

关键词： Synergy Nanoparticles Antibiotics Biorecycling microbes Antibacterial activities

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Antioxidant and lipoxygenase inhibitory properties of a novel flavonoid from Pistacia chinensis Bunge and its molecular docking analysis

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Traditional Medicine Research 2025年第2期10卷 30-36页

作者： Abdur Rauf Zuneera Akram Naveed Muhammad Najla AlMasoud Taghrid Saad Alomar Saima Naz Abdul Wadood chandni Hayat Marcello Iriti Department of Chemistry University of SwabiAmbar 23561Pakistan Department of Pharmacology Faculty of Pharmaceutical SciencesBaqai Medical UniversityKarachi 74600Pakistan Department of Pharmacy Abdul Wali Khan University MardanMardan 23200Pakistan Department of Chemistry College of SciencePrincess Nourah bint Abdulrahman UniversityRiyadh 11671Saudi Arabia Department of Biotechnology BKUC-Bacha Khan University CharsaddaCharsadda 24620Pakistan Department of Biochemistry Abdul Wali Khan University MardanMardan 23200Pakistan Department of Biomedical Surgical and Dental SciencesUniversity of MilanMilan 20129Italy National Interuniversity Consortium of Materials Science and Technology(INSTM) Firenze 50121Italy

Background:Pistacia chinensis Bunge has been traditionally used to manage various conditions,including asthma,pain,inflammation,hepatoprotection,and *** study was conducted to investigate the antioxidant and anti-lipoxygenase(LOX)properties of the isolated compound 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one from Pistacia ***:LOX assay and antioxidant activity using 2,2-diphenyl-1-picrylhydrazyl(DPPH)assay were *** docking studies were conducted using a molecular operating ***:The LOX assay revealed significant inhibitory effects at 0.2µM concentration,with an IC50 value of 37.80µ*** antioxidant effect demonstrated dose-dependency across 5 to 100µg/mL concentrations,reaching 93.09%at 100µg/mL,comparable to ascorbic acid’s 95.43%*** docking studies highlighted strong interactions with the lipoxygenase enzyme,presenting an excellent docking score of-10.98 kcal/***:These findings provide valuable insights into Pistacia chinensis’chemical components and biological effects,reinforcing its traditional medicinal applications.

关键词： Pistacia chinensis Bunge antioxidant DPPH assay antilipoxygenase docking analysis

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Deep insights into the advancements and applications of perovskite based photovoltaic cells

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Journal of Energy Chemistry 2018年第3期27卷 753-763页

作者： chandni Devi Rajesh Mehra Electronics and Communication Department NITTTR

The organometal halide perovskite materials have a blend of surprising optoelectronic properties, for example high value of absorption coefficient and abrupt optical retention edge, lifetime, long charge carrier diffusion length and many more. Brought in conjunction with the capacity for manufacturing at low temperature, likewise from the solution, devices based on perovskite, particularly solar cells have been contemplated seriously with striking advancements in performance, in the course of recent years. The amalgamation of minimal effort, high efficiency and extra applications gives incredible potential to commercialization of these cells. The applications and performance of perovskite cells frequently relate with the structures of the device. Numerous creative structures of the devices were produced, targeting for vast scale manufacture, diminishing creation cost, upgrading the PCE and subsequently expanding the prospective for future applications. This paper outlines the various advanced structures of PSC, challenges confronted by these PSCs and their future perspectives. The commercial applications of PSC are additionally talked about in this paper.

关键词： Solar cells Flexibility ETM Perovskite HTM Structures

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Building momentum for sustainable behaviors in developing regions using Locally Managed Decentralized Circular Economy principles

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Chinese Journal of Chemical Engineering 2019年第7期27卷 1566-1571页

作者： chandni Joshi Jeffrey Seay Department of Chemical and Materials Engineering University of Kentucky

Despite the current threat from climate change,plastic collecting in the world's oceans,and the steady loss of biodiversity,the world continually fails to take action with regard to our rapidly changing ***,waiting on governments to act is no longer a viable *** change is needed and the pace of diplomacy is simply too *** governments are reactionary and taking action to solve future problems is not a priority,even as the threat of potential ecological catastrophe draws ever *** is in the hands of individuals,and it is our decisions and behaviors that will influence the future of our planet and our ability to inhabit ***,building momentum for sustainable behavior must begin with *** neoliberal approach to environmental protection posits that individuals are motivated by rational self-interest,and that economic incentives are necessary to achieve environmental ***,recent research suggests that monetary gain alone actually negatively impacts behavior,and often neglects the rural *** a result,models for projects designed to benefit the environment need more than just a monetary incentive,they must incorporate all three pillars of sustainability:environment,economy and *** approach for building momentum for sustainable behavior with regard to municipal solid waste management,particularly in the developing world,is by implementing Locally Managed Decentralized Circular Economy(LMDCE)*** contribution will describe the role behavioral economics plays in the choices made by producers and *** results of a case study on applying LMDCE principles in Uganda to manage waste plastic accumulation by conversion to fuel oil will be presented.

关键词： Pyrolysis Fuel Pollution Appropriate technology Behavioral economics Municipal solid waste

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Efficient design of perovskite solar cell using mixed halide and copper oxide

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Chinese Physics B 2018年第1期27卷 607-613页

作者： Navneet kour Rajesh Mehra chandni Department of Electronics and Communication Engineering NITTTR

Solar cells based on perovskites have emerged as a transpiring technology in the field of photovoltaic. These cells exhibit high power conversion efficiency. The perovskite material is observed to have good absorption in the entire visible spectrum which can be well illustrated by the quantum efficiency curve. In this paper, theoretical analysis has been done through device simulation for designing solar cell based on mixed halide perovskite. Various parameters have efficacy on the solar cell efficiency such as defect density, layer thickness, doping concentration, band offsets, etc. The use of copper oxide as the hole transport material has been analyzed. The analysis divulges that due to its mobility of charge carriers, it can be used as an alternative to spiro-OMeTAD. With the help of simulations, reasonable materials have been employed for the optimal design of solar cell based on perovskite material. With the integration of copper oxide into the solar cell structure, the results obtained are competent enough. The simulations have shown that with the use of copper oxide as hole transport material with mixed halide perovskite as absorber, the power conversion efficiency has improved by 6%. The open circuit voltage has shown an increase of 0.09 V, short circuit current density has increased by 2.32 mA/cm2, and improvement in fill factor is 8.75%.

关键词： perovskite solar cell band offset device simulation hole transport material

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Spectroscopic study of strangeness=-3Ω^(-)baryon

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Chinese Physics C 2022年第10期46卷 43-51页

作者： chandni Menapara Ajay Kumar Rai Department of Physics Sardar Vallabhbhai National Institute of TechnologySurat-395007GujaratIndia

Ω^(-)baryon with sss quarks has been investigated through many theoretical studies so far but scarcely observed in ***,an attempt has been made to explore properties of Ω with hypercentral Constituent Quark Model(hCQM)with a linear confining *** resonance mass spectra have been obtained for 1S-4S,1P-4P,1D-3D,and *** Regge trajectory has been investigated for the linear nature based on calculated data along with the magnetic *** present work has been compared with various approaches and known experimental findings.

关键词： mass spectra strange baryon Regge trajectory magnetic moment

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Spectroscopic investigation of light strange S=−1Λ and Σ and S=−2Ξbaryons

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Chinese Physics C 2021年第6期45卷 91-108页

作者： chandni Menapara Ajay Kumar Rai Department of Physics Sardar Vallabhbhai National Institute of TechnologySurat-395007GujaratIndia

The present study is dedicated to light-strange∧with strangeness S=−1 and isospin I=0,with S=−1 and I=1,andΞbaryon with S=−2 andI=1/*** this study,the hypercentral constituent quark model with linear confining potential has been employed along with a first order correction term to obtain the resonance masses up to approximately 4 *** calculated states include 1S-5S,1P-4P,1D-3D,1F-2F,and 1G(in a few cases)along with all possible spin-parity *** trajectories have been explored for the linearity of the calculated masses for(n,M^(2))and(J,M^(2)).Magnetic moments have been intensively studied for ground state spin 1/2 and,3/2 in addition to the configuration mixing of the first negative parity state ***,the transition magnetic moments and radiative decay widths have been presented.

关键词： mass spectra strange baryon Regge trajectory magnetic moment

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Spectroscopic properties of Δ baryons

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Chinese Physics C 2021年第2期45卷 119-125页

作者： chandni Menapara Zalak Shah Ajay Kumar Rai Department of Applied Physics Sardar Vallabhbhai National Institute of TechnologySurat-395007GujaratIndia

The resonance state of theΔ baryon,which exists in four isospin(I=3/2)states,has been studied using the hypercentral constituent quark model(hCQM)with a simple linear potential with added first order *** calculated data ranges for 1S-5S,1P-5P,1D-4D and 1F-2F are given,with possible spin-parity assignments for all the *** magnetic moments have also been obtained for all four ***\pidecay channel width has been calculated for a few *** linear nature of the data has been verified through Regge trajectories.

关键词： mass spectra light baryon magnetic moment Regge trajectory

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A systematic review on the imaging findings in auditory neuropathy spectrum disorder

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Journal of Otology 2024年第3期19卷 166-172页

作者： Supriya Mathew chandni Jain Department of Audiology All India Institute of Speech and HearingMysuruKarnatakaIndia

Purpose:The present systematic review examined imaging findings in the Auditory Neuropathy Spectrum Disorder(ANSD)***:Electronic databases such as Pub Med,Google Scholar,J Gate,and Science Direct were used to conduct a literature *** articles retrieved through the literature search were assessed in two *** the first stage,title and abstract screening were done;in the second stage,a full-length article review was *** the 379 shortlisted records,19 articles were chosen for the full-length ***:The selected articles performed imaging using Computerized tomography(CT)and magnetic resonance imaging(MRI).In most studies,cochlear nerve deficiency(CND)was the most prevalent anomaly in the ANSD ***,MRI was the imaging modality of choice recommended in most *** was also noted that CND was a characteristic feature of unilateral ***:From this systematic review,it is clear that integrating imaging studies into diagnostic protocol would help to understand the underlying pathology better and expedite decision-making and intervention for ANSD patients.

关键词： ANSD Imaging Computerized tomography Magnetic resonance imaging Cochlear nerve deficiency

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Correlation of periodontal inflamed surface area with glycated hemoglobin,interleukin-6 and lipoprotein(a)in type 2 diabetes with retinopathy

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World Journal of Diabetes 2024年第4期15卷 686-696页

作者： Nusreen Jamal Thazhe Poyil Rosamma Joseph Vadakkekuttical chandni Radhakrishnan Department of Periodontics Government Dental College(Affiliated to Kerala University of Health Sciences)Calicut 673008KeralaIndia Department of Medicine Government Medical College(Affiliated to Kerala University of Health Sciences)Calicut 673008KeralaIndia

BACKGROUND The two-way relationship between periodontitis and type 2 diabetes mellitus(T2DM)is well *** hyperglycemia contributes to increased periodontal destruction and severe periodontitis,accentuating diabetic *** inflammatory link exists between diabetic retinopathy(DR)and periodontitis,but the studies regarding this association and the role of lipoprotein(a)[Lp(a)]and interleukin-6(IL-6)in these conditions are scarce in the *** To determine the correlation of periodontal inflamed surface area(PISA)with glycated Hb(HbA1c),serum IL-6 and Lp(a)in T2DM subjects with *** This cross-sectional study comprised 40 T2DM subjects with DR and 40 T2DM subjects without *** subjects were assessed for periodontal parameters[bleeding on probing(BOP),probing pocket depth,clinical attachment loss(CAL),oral hygiene index-simplified,plaque index(PI)and PISA],and systemic parameters[HbA1c,fasting plasma glucose and postprandial plasma glucose,fasting lipid profile,serum IL-6 and serum Lp(a)].RESULTS The proportion of periodontitis in T2DM with and without DR was 47.5%and 27.5%*** of periodontitis,CAL,PISA,IL-6 and Lp(a)were higher in T2DM with DR group compared to T2DM without DR *** difference was observed in the mean percentage of sites with BOP between T2DM with DR(69%)and T2DM without DR(41%),but there was no significant difference in PI(P>0.05).HbA1c was positively correlated with CAL(r=0.351,P=0.001),and PISA(r=0.393,P≤0.001)in study subjects.A positive correlation was found between PISA and IL-6(r=0.651,P<0.0001);PISA and Lp(a)(r=0.59,P<0.001);CAL and IL-6(r=0.527,P<0.0001)and CAL and Lp(a)(r=0.631,P<0.001)among study *** Despite both groups having poor glycemic control and comparable plaque scores,the periodontal parameters were higher in DR as compared to T2DM without *** a bidirectional link exists between periodontitis and DM,the presence of DR may have contr

关键词： Type 2 diabetes mellitus Periodontitis Periodontal inflamed surface Area Glycated Hb Diabetic retinopathy

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