检索结果-南通市图书馆

维普期刊数据库博看期刊

Health correlates, addictive behaviors, and peer victimization among adolescents in China

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2018年第5期14卷 454-460页

作者： Qi-Qi chen Meng-Tong chen Yu-Hong Zhu Ko Ling chan Patrick Ip Department of Applied Social Sciences The Hong Kong Polytechnic UniversityHung HomHong KongChina Department of Social Work Renmin University of ChinaHaidianBeijingChina Department of Pediatrics and Adolescent Medicine The University of Hong KongPokfulamHong KongChina

Background Peer victimization has been recognized as a common social problem affecting children and adolescents in all parts of the world. This study aims to examine the prevalence of different types of peer victimization and to evaluate the associations between peer victimization and health correlates. Methods Using a large population sample of 18,341 adolescents aged 15–17 years from 6 cities in China, this study esti-mated the prevalence of different types of peer victimization, addictive behaviors, and health-related variables with self-administrated questionnaires. A three-phase logistical regression analysis was conducted to investigate the associations between peer victimization and addictive behaviors as well as health-related factors among adolescents. Results A total of 42.9% of the surveyed Chinese adolescents have been bullied by peers, with boys reporting higher rate on overt victimization (36.9%) and girls on relational forms (33.9%). School environment (34.7%) was the most frequent scene of peer violence, followed by neighborhood, family, and internet. Addictive behaviors except substance abuse were found related to higher possibility of peer victimization (aOR 1.21–1.73, P<0.001). Peer victimization was significantly associated with more depressive symptoms, post-traumatic stress disorder symptoms, and suicide ideation and deliberate self-harm (aOR 1.05–2.27, P<0.001), and poorer self-esteem and health-related quality of life (aOR 0.95–0.97, P<0.001). Conclusion Possible explanations of the associations found in this study are discussed and implications for future services are raised.

关键词： Addictive behavior Adolescent Health Peer victimization

铁磁非晶丝对复合材料受力状态的响应行为研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

合成纤维 2024年第4期53卷 75-80页

作者：辛诚陈永当王海飞李婵西安工程大学机电工程学院陕西西安710600

采用VARTM工艺制备碳纤维增强树脂基复合材料和内嵌非晶丝的复合材料,通过铁磁非晶丝阻抗变化情况来分析复合材料的受力状态响应行为。试验结果表明:试件断裂损伤主要表现为基体裂纹的产生,层间出现分层断裂,材料损伤加剧直至整个试件... 详细信息

采用VARTM工艺制备碳纤维增强树脂基复合材料和内嵌非晶丝的复合材料,通过铁磁非晶丝阻抗变化情况来分析复合材料的受力状态响应行为。试验结果表明:试件断裂损伤主要表现为基体裂纹的产生,层间出现分层断裂,材料损伤加剧直至整个试件发生断裂;在各拉伸应力下,铁磁非晶丝的阻抗均表现出随着拉伸应力的增加先增加后减小的趋势,验证了铁磁非晶丝监测复合材料的结构健康的可行性。

关键词：铁磁非晶丝碳纤维复合材料 VARTM 阻抗

OSDA-free synthesis of FeZSM-22 zeolite from natural minerals for n -octane hydroisomerization

在线全文

学校读者我要写书评

暂无评论

miR-192对结直肠癌细胞系增殖、迁移和侵袭能力的影响

中国化学工程学报（英文版） 2024年第2期 51页

作者： Tiesen Li Ting chen Yinghui Ye Peng Dong Tinghai Wang Qingyan Cui chan Wang Yuanyuan Yue

来源：博看期刊评论

在线全文

博看期刊

学校读者我要写书评

暂无评论

国际检验医学杂志 2024年第1期45卷 60-63页

作者：陈颖李伟滔李娜周婵徐咏强南方医科大学附属东莞医院病理科广东东莞523059

目的探究微小RNA-192(miR-192)对结直肠癌(CC)细胞系增殖、迁移和侵袭能力的影响。方法分别设立A组(SW1116 CC细胞转染生理盐水)、B组(SW1116 CC细胞转染miR-192模拟物)及C组(SW1116 CC细胞转染miR-192抑制剂)。分别以MTT法检测各组... 详细信息

目的探究微小RNA-192(miR-192)对结直肠癌(CC)细胞系增殖、迁移和侵袭能力的影响。方法分别设立A组(SW1116 CC细胞转染生理盐水)、B组(SW1116 CC细胞转染miR-192模拟物)及C组(SW1116 CC细胞转染miR-192抑制剂)。分别以MTT法检测各组细胞增殖情况,以流式细胞术检测各组细胞凋亡情况,以划痕实验检测细胞迁移能力,以Transwell实验检测细胞侵袭能力。采用实时荧光定量聚合酶链式反应(qRT-PCR)检测各组细胞miR-192及WNT家族成员2B(WNT2B)mRNA表达水平。结果 B组SW1116 CC细胞存活率、单克隆形成数目分别为(57.32±6.19)%、(284.59±15.08)个,均低于A组的(76.21±8.23)%、(601.47±23.16)个与C组的(89.52±10.62)%、(2 150.68±34.79)个,而凋亡率为(20.52±2.52)%,高于A组的(13.78±1.62)%与C组的(11.62±1.41)%;C组SW1116 CC细胞存活率、单克隆形成数目均高于A组,而凋亡率低于A组(均P<0.05)。B组SW1116 CC细胞划痕宽度为(785.10±46.18)mm,高于A组的(601.32±33.21)mm与C组的(326.99±17.48)mm,而C组划痕宽度低于A组,B组穿膜细胞数为(624.67±19.05)个,少于A组的(875.23±27.30)个与C组的(1 204.17±34.59)个,且C组穿膜细胞数多于A组(均P<0.05)。B组SW1116 CC细胞miR-192 mRNA相对表达水平为(3.01±0.26),相较于A组的(1.87±0.20)及C组的(0.97±0.23)均更高,且C组miR-192 mRNA相对表达水平低于A组,B组WNT2B mRNA表达水平为(2.16±0.26),相较于A组的(4.11±0.50)与C组的(6.08±0.72)均更低,且C组WNT2B mRNA表达水平高于A组(均P<0.05)。结论 miR-192可抑制CC的恶性演进,其主要作用机制之一可能与调控WNT2B表达有关。

关键词：结直肠癌微小RNA-192 WNT家族成员2B 恶性演进机制

乙型肝炎病毒DNA载量对晚期肝细胞癌系统治疗安全性及预后的影响

在线全文

学校读者我要写书评

暂无评论

中华医学杂志 2024年第14期104卷 1160-1167页

作者：郑杏容彭建新宋欣刘波钟崇陈希瑶张博翔彭亮朱康顺谢婵中山大学附属第三医院感染性疾病科，广州510630 广州中医药大学第二附属医院肝胆外科，广州510120 中山大学附属第三医院普外科，广州510630 广州中医药大学第一附属医院肝胆外科，广州510405 广州医科大学附属第二医院微创介入科介入放射学实验室，广州510260

目的观察乙型肝炎(乙肝)病毒(HBV)阳性对接受系统治疗的晚期肝细胞癌(肝癌)患者发生肝损害、HBV再激活(HBVr)及HBVr对系统治疗预后的影响。方法回顾性收集2018年7月至2020年12月中山大学附属第三医院等4家医院403例乙肝相关肝癌患者的... 详细信息

目的观察乙型肝炎(乙肝)病毒(HBV)阳性对接受系统治疗的晚期肝细胞癌(肝癌)患者发生肝损害、HBV再激活(HBVr)及HBVr对系统治疗预后的影响。方法回顾性收集2018年7月至2020年12月中山大学附属第三医院等4家医院403例乙肝相关肝癌患者的临床资料,分析系统治疗期间肝损害及HBVr发生率,并分析HBVr对生存预后的影响。结果共纳入403例患者,359例(89.1%)为男性,年龄(51.5±12.1)岁。进行倾向性评分匹配(PSM)前,高HBV-DNA(基线HBV-DNA>1000 U/ml,n=147)组与低HBV-DNA(基线HBV DNA≤1000 U/ml,n=256)组相比,肝硬化、TNM及巴塞罗那分期(BCLC)晚期患者比例较高(P0.05)。对169例有生存数据的患者进行生存分析,发现高HBV-DNA组和低HBV-DNA组的中位总生存期(OS)分别为11.49个月(95%CI:7.77~12.89)和16.65个月(95%CI:10.54~21.99,P=0.008),中位无进展生存期(PFS)分别为7.41个月(95%CI:5.06~8.67)和10.55个月(95%CI:6.72~13.54,P=0.038),差异均有统计学意义,但有无HBVr、有无肝损害的患者OS和PFS差异均无统计学意义(均P>0.05)。结论系统治疗前HBV-DNA>1000 U/ml并不增加乙肝相关肝癌患者系统治疗时肝损害或HBVr的风险,该类患者可以安全地接受系统治疗。

关键词：免疫治疗肝细胞癌慢性乙型病毒性肝炎安全性

Effects of BTA2 as the third component on the charge carrier generation and recombination behavior of PTB7:PC71BM photovoltaic system

在线全文

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2021年第1期15卷 127-137页

作者： Leijing Liu Hao Zhang Bo Xiao Yang Liu Bin Xu chen Wang Shanpeng Wen Erjun Zhou Gang chen chan Im Wenjing Tian State Key Laboratory of Supramolecular Structures and Materials Jilin UniversityChangchun 130012China CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China State Key Laboratory on Integrated Optoelectronics and College of Electronic Science&Engineering Jilin UniversityChangchun 130012China Key Laboratory of Physics and Technology for Advanced Batteries Ministry of EducationJilin UniversityChangchun 130012China Department of Chemistry Konkuk UniversitySeoul 05029Republic of Korea

Effects of a benzotriazole(BTA)-based small molecule,BTA2,as the third component on the charge carrier generation and recombination behavior of poly[[4,8-bis[(2-ethylhexyl)oxy]benzo[1,2-b:4,5-b']dithiophene-2,6-diyl][3-fluoro-2-[(2-ethylhexyl)carbonyl]thieno[3,4-b]thiophenediyl]](PTB7):[6,6]-phenyl-C71-butyric acid methyl ester(PC71BM)organic solar cells(OSCs)were investigated by optical simulation of a transfer matrix model(TMM),photo-induced charge extraction by linearly increasing voltage(photo-CELIV)technique,atomic force microscope(AFM),and the Onsager–Braun model ***2 is an A_(2)-A_(1)-D-A_(1)-A_(2)-type non-fullerene small molecule with thiazolidine-2,4-dione,BTA,and indacenodithiophene as the terminal acceptor(A_(2)),bridge acceptor(A_(1)),and central donor(D),*** short-circuit current density of the OSCs with BTA2 can be enhanced significantly owing to a complementary absorption *** optical simulation of TMM shows that the ternary OSCs exhibit higher internal absorption than the traditional binary OSCs without BTA2,resulting in more photogenerated excitons in the ternary *** photo-CELIV investigation indicates that the ternary OSCs suffer higher charge trap-limited bimolecular recombination than the binary *** images show that BTA2 aggravates the phase separation between the donor and the acceptor,which is disadvantageous to charge carrier *** Onsager-Braun model analysis confirms that despite the charge collection efficiency of the ternary OSCs being lower than that of the binary OSCs,the optimized photon absorption and exciton generation processes of the ternary OSCs achieve an increase in photogenerated current and thus improve power conversion efficiency.

关键词： third component organic solar cells charge carrier generation charge carrier recombination bimolecular recombination

Data-Driven Prediction of Mechanical Properties in Support of Rapid Certification of Additively Manufactured Alloys

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2018年第12期117卷 343-366页

作者： Fuyao Yan Yu-Chin chan Abhinav Saboo Jiten Shah Gregory BOlson Wei chen Department of Materials Science and Engineering Northwestern University2220 Campus DrEvanstonIL 60208USA Department of Mechanical Engineering Northwestern University2145 Sheridan RdEvanstonIL 60208USA QuesTek Innovations LLC 1820 Ridge AveEvanstonIL 60201USA Product Development&Analysis LLC 1776 Legacy CircleSuite#115NapervilleIL 60563USA.

Predicting the mechanical properties of additively manufactured parts is often a tedious process,requiring the integration of multiple stand-alone and expensive ***,as properties are highly location-dependent due to repeated heating and cooling cycles,the properties prediction models must be run for multiple locations before the part-level performance can be analyzed for certification,compounding the computational *** work has proposed a rapid prediction framework that replaces the physics-based mechanistic models with Gaussian process metamodels,a type of machine learning model for statistical inference with limited *** metamodels can predict the varying properties within an entire part in a fraction of the time while providing uncertainty *** framework was demonstrated with the prediction of the tensile yield strength of Ferrium?PH48S maraging stainless steel fabricated by additive *** agreement was found between the metamodels and the mechanistic models,and the computation was dramatically decreased from hours of physics-based simulations to less than a second with *** method can be extended to predict various materials properties in different alloy systems whose processstructure-property-performance interrelationships are linked by mechanistic *** is powerful for rapidly identifying the spatial properties of a part with compositional and processing parameter variations,and can support part certification by providing a fast interface between materials models and part-level thermal and performance simulations.

关键词： Additive manufacturing spatially-varying properties Gaussian process modeling statistical sensitivity analysis maraging stainless steel yield strength.

甘蔗渣和菠萝渣对黑水虻幼虫生长发育和肠道微生物的影响

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

环境昆虫学报 2024年第5期46卷 1245-1254页

作者：岳海林陈慧婵管文菲刘文谢秀凤陈礼芬董斌黄敏叶明强广东农工商职业技术学院广州510665 广东省农业科学院蚕业与农产品加工研究所广州510610

本研究旨在研究甘蔗渣和菠萝渣饲喂黑水虻Hermetia illucens幼虫对其幼虫的生长性能及其肠道微生物的影响。试验分别以未发酵和自然发酵的甘蔗渣、菠萝渣为基础饲料,辅以不同比例的豆腐渣配制成不同饲料配方喂养黑水虻,测定黑水虻幼虫... 详细信息

本研究旨在研究甘蔗渣和菠萝渣饲喂黑水虻Hermetia illucens幼虫对其幼虫的生长性能及其肠道微生物的影响。试验分别以未发酵和自然发酵的甘蔗渣、菠萝渣为基础饲料,辅以不同比例的豆腐渣配制成不同饲料配方喂养黑水虻,测定黑水虻幼虫的生长性能及肠道微生物。结果显示,与以纯豆腐渣为基础饲料的对照(CK)相比,处理Ⅳ(80%发酵菠萝渣+20%豆腐渣)喂养黑水虻幼虫可显著提高预蛹前黑水虻幼虫平均体长、体重、生长性能及饲料利用率,降低料重比,养殖7 d后幼虫平均体长、体重、获得生物量、生长率、饲料利用率分别比CK高11.58%、46.69%、47.12%、46.75%、24.10%,料重比降低了19.18%。分别与以未发酵果渣为基础饲料的处理(Ⅰ、Ⅲ)相比,处理Ⅱ和Ⅳ提高了黑水虻预蛹前幼虫平均体长、体重、幼虫生长率和饲料利用率,降低了料重比。黑水虻幼虫肠道菌群聚类良好,处理Ⅰ~Ⅳ黑水虻幼虫肠道中,拟杆菌门的平均相对丰度显著高于CK,而处理Ⅱ~Ⅳ厚壁菌门的平均相对丰度显著低于CK,处理Ⅰ厚壁菌门的平均相对丰度差异低于CK但不显著。与CK比,处理Ⅰ~Ⅳ黑水虻幼虫肠道中,营发酵单胞菌属相对丰度(40.10%以上)显著增加,肠球菌属相对丰度显著降低,摩根氏菌属、放线菌属相对丰度降低但差异不显著,普罗威登斯菌属相对丰度增加但差异不显著。研究表明,处理Ⅳ黑水虻幼虫生长性能和饲料转化性能优于其他处理,发酵果渣处理优于非发酵处理,且不同饲料配方会引起黑水虻幼虫肠道菌群相对丰度的改变。

关键词：甘蔗渣菠萝渣黑水虻幼虫生长性能肠道微生物

Peptide asparaginyl ligases——renegade peptide bond makers

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2020年第3期63卷 296-307页

作者： James P.Tam Ning-Yu chan Heng Tai Liew Shaun J.Tan Yu chen School of Biological Sciences Nanyang Technological UniversitySingapore 637551Singapore Synzymes and Natural Products Center Nanyang Technological UniversitySingapore 637551Singapore NTU Institute of Structural Biology Nanyang Technological UniversitySingapore 636921Singapore

Making peptide bonds is tightly controlled by genetic code and machinery which includes cofactors,ATP,and *** this regard,the stand-alone and genetic-code-independent peptide ligases constitute a new family of renegade peptide-bond makers.A prime example is butelase-1,an Asn/Asp(Asx)-specific ligase that structurally belongs to the asparaginyl endopeptidase ***-1 specifically recognizes a C-terminal Asx-containing tripeptide motif,Asn/Asp-Xaa-Yaa(Xaa and Yaa are any amino acids),to form a site-specific Asn-Xaa peptide bond either intramolecularly as cyclic proteins or intermolecularly as modified *** work in the past five years has validated that butelase-1 is a potent and versatile *** we review the advances in ligases,with a focus on butelase-1,and their applications in engineering bioactive peptides and precision protein modifications,antibody-drug conjugates,and live-cell labeling.

关键词： asparaginyl endopeptidase Asn-specific ligation bioorthogonal ligation butelase chemoenzymatic ligation live-cell labeling protein engineering protein modification site-specific labeling tandem ligation