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Absence of enhancement in a lesion does not preclude primary central nervous system T-cell lymphoma:A case report

World Journal of Clinical Cases 2024年第2期12卷 374-382页

作者： chan-seop kim Chi-Hoon Choi Kyung Sik Yi Yook kim Jisun Lee chang Gok Woo Young Hun Jeon Department of Radiology Chungbuk National University HospitalChungbuk National University College of MedicineCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Pathology Chungbuk National University HospitalChungbuk National University College of MedicineCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Radiology Seoul National University HosptialSeoul 03080South Korea

BACKGROUND Primary central nervous system lymphoma(PCNSL)is a non-Hodgkin lymphoma that originates in the central nervous system(CNS)and is exclusively limited to the *** most PCNSLs are diffuse large B-cell lymphomas,primary CNS T-cell lymphomas(PCNSTLs)are *** typically demonstrate some degree of enhancement on contrast-enhanced magnetic resonance imaging(MRI).To the best of our knowledge,non-enhancing PCNSTL has not been reported *** SUMMARY A 69-year-old male presented to the neurology department with complaints of mild cognitive impairment and gradual onset of left lower leg weakness over a span of two *** MRI showed asymmetric T2-hyperintense lesions within the *** enhancement was observed on the contrast-enhanced T1 *** initial diagnosis was neuro-Behçet’s *** high-dose steroid therapy,no alterations in the lesions were identified on initial *** patient’s symptoms deteriorated *** MRI performed one month after the initial scan revealed an increased lesion ***,brain biopsy confirmed the diagnosis of *** patient underwent definitive combined ***,the patient developed bacteremia and died of septic shock approximately three months after *** The absence of enhancement in the lesion did not rule out PCNSTL.A biopsy approach is advisable for pathological confirmation.

关键词： Central nervous system neoplasms Non-Hodgkin Lymphoma T-cell Lymphoma Primary central nervous system lymphoma Primary central nervous system T-cell lymphoma Case report

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Fostering tissue engineering and regenerative medicine to treat musculoskeletal disorders in bone and muscle

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Bioactive Materials 2024年第10期40卷 345-365页

作者： Soyeon Park Khandoker Asiqur Rahaman Yu-chan kim Hojeong Jeon Hyung-seop Han Biomaterials Research Center Biomedical Research DivisionKorea Institute of Science and TechnologySeoul02792Republic of Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul02841Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea

The musculoskeletal system,which is vital for movement,support,and protection,can be impaired by disorders such as osteoporosis,osteoarthritis,and muscular *** review focuses on the advances in tissue engineering and regenerative medicine,specifically aimed at alleviating these *** explores the roles of cell therapy,particularly Mesenchymal Stem Cells(MSCs)and Adipose-Derived Stem Cells(ADSCs),biomaterials,and biomolecules/external stimulations in fostering bone and muscle *** current research underscores the potential of MSCs and ADSCs despite the persistent challenges of cell scarcity,inconsistent outcomes,and safety ***,integrating exogenous materials such as scaffolds and external stimuli like electrical stimulation and growth factors shows promise in enhancing musculoskeletal *** review emphasizes the need for comprehensive studies and adopting innovative techniques together to refine and advance these multi-therapeutic strategies,ultimately benefiting patients with musculoskeletal disorders.

关键词： Musculoskeletal disorders Tissue engineering Regenerative medicine Bone Muscle

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Fabrication of Fullerene-Reinforced Aluminum Matrix Nanocomposites

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Acta Metallurgica Sinica(English Letters) 2017年第10期30卷 973-982页

作者： Hamed Asgharzadeh Hamid Faraghi Hyoung seop kim Department of Materials Engineering Faculty of Mechanical EngineeringUniversity of Tabriz Department of Materials Science and Engineering Pohang University of Science and Technology (POSTECH)

Fullerene-reinforced A1 matrix nanocomposites were fabricated by high-energy mechanical milling followed by consolidation through hot extrusion or high-pressure torsion（HPT）. The results indicate that a relatively homogeneous microstructure consisting of elongated, micrometer-sized A1 grains is formed in the hot-extruded specimens. However, the microstructure is not uniform along the radius of the HPT disks, which includes coarse grains near the center of the disk and ultrafine grains in the middle and along the edge of the specimen. Microstructural evaluations of the HPT disks indicate that A1 grain refinement occurs due to the addition of fullerene, as grain size is reduced to 60 nm from 118 nm. The formation of the harmful aluminum carbide phase is not detected during the fabrication of Al/C（60） nanocomposites. The hardness, yield stress, and ultimate tensile strength of the Al-2 vol.% C（60） nanocomposites are about 27-160% higher than those of the monolithic A1 samples, revealing the effective strengthening of fullerene particles in A1 matrix. Moreover,mechanical properties of the Al/fullerene nanocomposites are significantly enhanced（59-272%） by utilizing HPT in comparison to hot-extruded specimens due to their much finer A1 grain structure. The reduction in the number and the size of the dimples, as well as the formation of smooth regions on the tensile fracture surface of Al/C（60）, results in their overall lower ductility compared to monolithic Al.

关键词： Aluminum Fullerene High-pressure torsion Hot extrusion Microstructure Mechanical properties

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Investigation of long-wavelength elastic wave propagation through wet bentonite-filled rock joints

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第10期15卷 2496-2507页

作者： Ji-Won kim Song-Hun Chong Jin-seop kim Geon-Young kim Disposal Performance Demonstration R&D Division Korea Atomic Energy Research InstituteDaejeon34057Republic of Korea Department of Civil Engineering Sunchon National UniversitySuncheon57922Republic of Korea

The saturation of the compacted bentonite buffer in the deep geological repository can cause bentonite swelling,intrusion into rock fractures,and ***,erosion and subsequent bentonite mass loss due to groundwater inflow can aggravate the overall integrity of the engineered barrier ***,the coupled hydro-mechanical interaction between the buffer and rock during groundwater inflow and bentonite intrusion should be evaluated to guarantee the long-term safety of deep geological *** study investigated the effect of bentonite erosion and intrusion on the elastic wave propagation characteristics in jointed rocks using a quasi-static resonant column *** rock specimens with different joint conditions(*** surface saturation and bentonite filling)were prepared using granite rock discs sampled from the Korea Underground Research Tunnel(KURT)and Gyeongju *** long-wavelength longitudinal and shear wave velocities were measured under different normal stress levels.A Hertzian-type power model was used to fit the wave velocities,and the relationship between the two fitted parameters provided the trend of joint *** simulations using three-dimensional distinct element code(3DEC)were conducted to better understand how the long-wavelength wave propagates through wet bentonite-filled rock joints.

关键词： Engineered barrier system Bentonite erosion and intrusion Jointed rock mass Long-wavelength elastic wave velocity Quasi-static resonant column test Three-dimensional distinct element code(3DEC)

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A neural network model for high entropy alloy design

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npj Computational Materials 2023年第1期9卷 1734-1746页

作者： Jaemin Wang Hyeonseok Kwon Hyoung seop kim Byeong-Joo Lee Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Graduate Institute of Ferrous and Energy materials Technology(GIFT) Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Center for Heterogenic Metal Additive Manufacturing Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Institute for Convergence Research and Education in Advanced Technology Yonsei UniversitySeoul 03722Republic of Korea Advanced Institute for Materials Research(WPI-AIMR) Tohoku UniversitySendai 980-8577Japan

A neural network model is developed to search vast compositional space of high entropy alloys(HEAs).The model predicts the mechanical properties of HEAs better than several other ***’s because the special structure of the model helps the model understand the characteristics of constituent elements of *** addition,thermodynamics descriptors were utilized as input to the model so that the model predicts better by understanding the thermodynamic properties of HEAs.A conditional random search,which is good at finding local optimal values,was selected as the inverse predictor and designed two HEAs using the *** experimentally verified that the HEAs have the best combination of strength and ductility and this proves the validity of the model and alloy design *** strengthening mechanism of the designed HEAs is further discussed based on microstructure and lattice distortion *** present alloy design approach,specialized in finding multiple local optima,could help researchers design an infinite number of new alloys with interesting properties.

关键词： alloy alloys microstructure

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Computational design of Mg alloys with minimal galvanic corrosion

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Journal of Magnesium and Alloys 2022年第7期10卷 1972-1980页

作者： Krishnamohan Thekkepat Hyung-seop Han Ji-Won Choi Seung-Cheol Lee Eul Sik Yoon Guangzhe Li Hyun-Kwang Seok Yu-chan kim Jae-Hun kim Pil-Ryung Cha Indo-Korea Science and Technology Center JakkurBangalore 560065India Division of Nano&Information Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea Electronic Materials Research Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea Center for Biomaterials Biomedical Research InstituteKorea Institute of Science and TechnologySeoul 02792Republic of Korea Department of Plastic and Reconstructive Surgery Korea University College of MedicineSeoul 02841Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul 02792Republic of Korea School of Advanced Materials Engineering Kookmin UniversitySeoul 02707Republic of Korea

Formation of galvanic cells between constituent phases is largely responsible for corrosion in Mg-based *** develop a methodology to calculate the electrochemical potentials of intermetallic compounds and alloys using a simple model based on the Born-Haber *** electrochemical potentials are used to predict and control the formation of galvanic cells and minimize *** demonstrate the applicability of our model by minimizing galvanic corrosion in Mg-3wt%Sr-x Zn alloy by tailoring the Zn *** methodology proposed in this work is applicable for any general alloy system and will facilitate efficient design of corrosion resistant alloys.

关键词： Galvanic corrosion First-principles Cluster expansion Thermodynamics Modeling Magnesium alloys

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Superior anti-icing strategy by combined sustainable liquid repellence and electro/photo-responsive thermogenesis of oil/MWNT composite

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Journal of Materials Science & Technology 2020年第14期47卷 106-116页

作者： Aeree kim Seonghyeon kim Myoung Huh Hyungmo kim chan Lee Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang37673Republic of Korea Korea Atomic Energy Research Institute(KAERI) Daejeon34057Republic of Korea

This paper introduces an effective anti-icing strategy that uses passive anti-icing property and active de-icing functions *** dual capabilities can alleviate the icing problem more effectively than either a passive or active function *** developed material is a slippery liquid-repellent elastic conductor(SLEC);it is an organogel that is composed of multi-walled carbon nanotubes,oil,and *** SLEC maintains passive water-droplet sliding ability even on wet surfaces that frequently occur in cold conditions(e.g.,during condensation and defrosting),suppresses ice nucleation,and shows ice adhesion strength as low as^20 *** SLEC releases heat when it is subject to electrical or photonic stimulation,and can therefore it can prevent ice formation and melt ice that has already formed on a *** material has sustainable liquid repellence by syneresis and replenishment;this ability ensures long-lasting anti-icing property,and results in exceptional *** durability is stable against mechanical *** superior dual anti-icing capabilities together with the sustainable and stable liquid repellence should generate synergistic effects,and yield a powerful anti-icing tool that can broaden the range of icing applications.

关键词： Anti-icing De-icing Icephobic Soft conductor Self-healing Nanocomposite Liquid repellence

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Improving ionic conductivity of von-Alpen-type NASICON ceramic electrolytes via magnesium doping

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Journal of Advanced Ceramics 2023年第5期12卷 1058-1066页

作者： Il-seop Jang Wooseok Go Bo-Ye Song Hayoung Park Yun chan Kang Jinyoung Chun Emerging Materials R&D Division Korea Institute of Ceramic Engineering and Technology(KICET)Jinju 52851Republic of Korea Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea Energy Storage and Distribution Resources Division Lawrence Berkeley National LaboratoryBerkeley 94720USA

NASICON (sodium (Na) superionic conductor) compounds have attracted considerable attention as promising solid electrolyte materials for advanced Na-based batteries. In this study, we investigated the improvement in ionic conductivities of von-Alpen-type NASICON (vA-NASICON) ceramic electrolytes by introducing a magnesium ion (Mg^(2+)) as a heterogeneous element. The optimal Mg-doped vA-NASICON exhibited a high ionic conductivity of 3.64×10^(−3) S·cm^(−1), which was almost 80% higher than that of un-doped vA-NASICON. The changes in physicochemical properties of the vA-NASICONs through the Mg introduction were systematically analyzed, and their effects on the ionic conductivities of the vA-NASICON were studied in detail. When the optimal ratio of Mg^(2+) was used in a synthetic process, the relative density (96.6%) and grain boundary ionic conductivity (σgb) were maximized, which improved the total ionic conductivity (σt) of the vA-NASICON. However, when Mg^(2+) was introduced in excess, the ionic conductivity decreased because of the formation of an undesired sodium magnesium phosphate (NaxMgyPO_(4)) secondary phase. The results of this study are expected to be effectively applied in the development of advanced sodium-based solid electrolytes with high ionic conductivities.

关键词： NASICON solid electrolyte von-Alpen-type magnesium(Mg)doping ionic conductivity

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On Univalence of the Power Deformation z（f（z）/z）c

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Chinese Annals of Mathematics,Series B 2012年第6期33卷 823-830页

作者： Yong chan kim Toshiyuki SUGAWA Department of Mathematics Education Yeungnam University Graduate School of Information Sciences Tohoku University

The authors mainly concern the set Uf of c E C such that the power deformation z（f-（z）/z）c is univalent in the unit disk ｜z｜〈 1 for a given analytic univalent function f（z） = z ＋ a2z2 ＋ ... in the unit disk. It is shown that Uf is a compact, polynomially convex subset of the complex plane C unless f is the identity function. In particular, the interior of Uf is simply connected. This fact enables us to apply various versions of the X-lemma for the holomorphic family z（f（z）/z）c of injections parametrized over the interior of Uf. The necessary or sufficient conditions for Uf to contain 0 or 1 as an interior point are also given.

关键词： Univalent function Holomorphic motion Quasiconformal extension Grunsky inequality Univalence criterion

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Yolk-shell-structured （***.s）9S8 solid-solution powders：Synthesis and application as anode materials for Na-ionbatteries

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Nano Research 2017年第9期10卷 3178-3188页

作者： Jung Hyun kim Yun chan Kang Department of Materials Science and Engineering Korea University Anam-Dong Seongbuk-Gu Seou1136-713 Republic of Korea

Multicomponent metal sulfide materials with a yolk–shell structure and a single phase were studied for the first time as anode materials for sodium-ion batteries. Yolk–shell-structured Fe–Ni–O powders with a molar ratio of iron and nickel components of 1/1 were prepared via one-pot spray pyrolysis. The prepared Fe–Ni–O powders were transformed into yolk–shell-structured (Fe0.5Ni0.5)9S8 solid-solution powders via a sulfidation process. The initial discharge and charge capacities of the (Fe0.5Ni0.5)9S8 powders at a current density of 1 A·g−1 were 601 and 504 mA·h·g−1, respectively. The discharge capacities of the (Fe0.5Ni0.5)9S8 powders for the 2nd and 100th cycle were 530 and 527 mA·h·g−1, respectively, and their corresponding capacity retention measured from the 2nd cycle was 99%. The (Fe0.5Ni0.5)9S8 powders had high initial discharge and charge capacities at a low current density of 0.1 A·g−1, and the reversible discharge capacity decreased slightly from 568 to 465 mA·h·g−1 as the current density increased from 0.1 to 5.0 A·g−1. The synergetic effect of the novel yolk–shell structure and the multicomponent sulfide composition of the (Fe0.5Ni0.5)9S8 powders resulted in excellent sodium-ion storage performance.

关键词： metal sulfide multicomponent sulfide yolk–shell sodium-ion batteries spray pyrolysis

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