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Journal of Magnesium and Alloys 2019年第4期7卷 648-660页

作者： Jong Un Lee Ye Jin Kim Sang-Hoon Kim Jeong Hun Lee Min-Seong Kim Shi-Hoon Choi Byoung Gi Moon Young Min Kim Sung hyuk park School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Ulsan Regional Division Korea Institute of Industrial TechnologyUlsan 44413Republic of Korea Department of Printed Electronics Engineering Sunchon National UniversitySuncheonJeonnam 57922Republic of Korea Implementation Research Division Korea Institute of Materials ScienceChangwon 51508Republic of Korea

In this study,the texture of a rolled Mg alloy is effectively modified through the application of precompression and subsequent annealing treatment,leading to a remarkable improvement in the bending formability of the alloy at room *** induces lattice reorientation through{10-12}twinning,and annealing treatment reduces the stored strain energy of the precompressed material,which results in the formation of a stable grain structure with two dominant texture *** an increase in precompression,the tensile strain in the outer region of the bending samples is accommodated to a greater extent due to more pronounced{10-12}twinning and basal *** a result,the bending formability of the material at room temperature improves with greater *** variation in microstructure,texture,and bending behavior in relation to the degree of precompression is discussed in detail.

关键词： Magnesium Bending Formability Twinning Texture

Patients’perspectives on the conventional synthetic cast vs a newly developed open cast for ankle sprains

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World Journal of Orthopedics 2020年第11期11卷 492-498页

作者： Byung Cho Min Ji Soo Yoon Chin Youb Chung Moon Seok park Ki hyuk Sung Kyoung Min Lee Department of Orthopaedic Surgery Seoul National University Bundang HospitalSeongnam 463-707GyeonggiSouth Korea

BACKGROUND Orthopedic physicians typically apply a cast to immobilize a body part that has been *** have been no significant structural changes or advances in synthetic casts since the development of the modern *** Opencast®is a recently developed type of cast that allows ventilation and direct visual inspection of the skin to avoid cast-related *** this novel cast appears to have more benefits than the conventional synthetic cast,its clinical efficacy and advantages have not been *** To investigate the clinical efficacy and advantages of the newly developed Opencast®based on patients’perspectives in those with ankle inversion *** A specifically designed questionnaire consisting of 19 items was used to compare patients’opinions and concerns of the Opencast®and the conventional synthetic *** items were focused on subjective patient satisfaction,discomfort,and adverse effects while wearing the *** with an ankle inversion injury diagnosed as a high-grade ankle sprain were *** subjects were randomized and instructed to fill the questionnaire after wearing a synthetic cast or an Opencast®for 2 *** were then required to fill the questionnaire again,after switching to the alternative type of cast for 2 more *** A total of 22 subjects participated in the *** synthetic cast appeared to be more rigid and stable than the Opencast®,but there was no significant difference in the amount of pain *** likelihood of adverse effects when wearing the synthetic cast was significantly *** satisfaction tended to be rated higher after wearing the Opencast®.Opencast®showed more subjective vulnerability than the synthetic cast,but there was no significant difference in the redo *** were more anxious about removal of the synthetic cast than of the Opencast®.CONCLUSION The results indicate that the Opencast®could replace the conventional synthetic cast as it offers i

关键词： Clinical utility Comparison Open cast Conventional cast Cast material Ankle sprain

Low-dose amitriptyline combined with proton pump inhibitor for functional chest pain

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World Journal of Gastroenterology 2013年第30期19卷 4958-4965页

作者： Se Woo park hyuk Lee Hyun Jik Lee Jun Chul park Sung Kwan Shin Sang Kil Lee Yong chan Lee Ji Eun Kim Department of Internal Medicine Institute of GastroenterologyYonsei University College of Medicine Biostatistics Collaboration Unit Yonsei University College of Medicine

AIM:To investigate the efficacy of amitriptyline with proton pump inhibitor(PPI)for the treatment of functional chest pain(FCP).METHODS:This was a randomized,open-label trial investigating the addition of low dose amitriptyline(10 mg at bedtime)to a conventional dose of rabeprazole(20 mg/d)(group A,n = 20)vs a double-dose of rabeprazole(20 mg twice daily)(group B,n = 20)for patients with FCP whose symptoms were refractory to *** primary efficacy endpoints were assessed by global symptom score assessment and the total number of individuals with > 50% improvement in their symptom ***:The between-group difference in global symptom scores was statistically significant during the last week of treatment(overall mean difference;3.75 ± 0.31 vs 4.35 ± 0.29,the between-group difference;P 50%,whereas only 26.3% of patients in group B had a similar treatment response(70.6% vs 26.3%,P = 0.008).Specifically,patients in group A had a significantly greater improvement in the domains of body pain and general health perception than did patients in group B(52.37 ± 17.00 vs 41.32 ± 12.34,P = 0.031 and 47.95 ± 18.58 vs 31.84 ± 16.84,P = 0.01,respectively).CONCLUSION:Adding amitriptyline to a PPI was more effective than a double-dose of PPI in patients with FCP refractory to a conventional dose of PPI.

关键词： Functional chest pain Proton pump inhibitor Amitriptyline

Pattern of instent neointimal formation compared to native atherosclerosis in the coronary bifurcation lesions： volumetric intravascular ultrasound analysis

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Chinese Medical Journal 2013年第18期126卷 3505-3510页

作者： XU Jian-qiang Young Bin Song Joo-Yong Hahn Seung-hyuk Choi Jin-Ho Choi LU Cheng-zhi Sang Hoon Lee Kyung Pyo Hong Jeung Euy park Hyeon-Cheol Gwon Division of Cardiology Department of Medicine Samsung MedicalCenter Sungkyunkwan University School of Medicine Seoul Korea Cardiovascular CenterTianjin First Central Hospital Tianjin 300192 China

Background No clinical study has systematically analyzed and compared circumferential neointimal and plaque distribution of stent neointimal proliferation and in native atherosclerotic plaques. This study aimed to investigate and compare the pattern of instent neointimal formation and native atherosclerosis in the coronary bifurcation lesions by volumetric analysis using systematic intravascular ultrasound （IVUS）. Methods We examined bifurcation lesions in native coronary artery （plaque group, n=102） and stented bifurcations at 9-month follow-up （neointima group, n=51） using volumetric IVUS analysis of both the main vessel （MV） and side branch （SB）. Three 5-mm segments were analyzed; the proximal MV （MVp）, distal MV （MVd） and SB ostium （SBo）. For each segment, volumetric analysis was performed in each of four quadrants （divided according to the branch takeoff and the geometric center of the lumen）; carinal, epicardial, abcarinal, and myocardial. The eccentricity index was defined as the ratio of the abcarinal plaque （or neointimal） volume to the carinal plaque （or neointimal） volume. Results The plaque distribution differed significantly between the four quadrants, with the largest in the abcarinal quadrant, followed by the myocardial, epicardial, and carinal quadrants. The distribution of neointima was similar in the MV, but the four quadrants in the SB did not differ significantly. The eccentricity indices of both the MVd （P 〈0.001） and SBo （P=-0.001） were significantly higher for the plaque group than the neointima group. Conclusions The distribution of neointimal proliferation seems to have a similar pattern to that of atherosclerotic plaque in native coronary arteries. Darticularlv in the main vessel, but the trend is less prominent.

关键词： atherosclerosis bifurcations plaque distribution neointimal distribution intravascular ultrasound

A case of hypereosinophilic syndrome presenting with intractable gastric ulcers

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World Journal of Gastroenterology 2009年第48期15卷 6129-6133页

作者： Tae Young park chang Hwan Choi Suh Yoon Yang InSoo Oh In-Do Song Hyun Woong Lee Hyung Joon Kim Jae hyuk Do Sae Kyung chang Ah Ra Cho Young Joo Cha Department of Internal Medicine Chung-Ang University College of Medicine Department of Laboratory Medicine Chung-Ang University College of Medicine

We report a rare case of hypereosinophilic syndrome(HES)presenting with intractable gastric ulcers.A 71-year-old man was admitted with epigastric *** endoscopic findings revealed multiple,active gastric ulcers in the gastric *** underwent Helicobacter pylori(H pylori)eradication therapy followed by proton pump inhibitor(PPI)***,follow-up endoscopy at 4,6,10 and 14 mo revealed persistent multiple gastric ulcers without significant *** proportion of his eosinophil count increased to 43%(total count:7903/mm 3).Abdominal-pelvic and chest computed tomography scans showed multiple small nodules in the liver and both *** endoscopic biopsy specimen taken from the gastric antrum revealed prominent eosinophilic infiltration,and the liver biopsy specimen also showed eosinophilic infiltration in the portal tract and sinusoid.A bone marrow biopsy disclosed eosinophilic hyperplasia as well as increased cellularity of 70%.The patient was finally diagnosed with HES involving the stomach,liver,lung,and bone *** gastric ulcers do not improve despite H pylori eradication and prolonged PPI therapy,infiltrative gastric disorders such as HES should be considered.

关键词：胃溃疡顽固性嗜酸粒细胞嗜酸性粒细胞综合征扫描显示质子泵抑制剂价格指数

Comparison of sequential and 7-,10-,14-d triple therapy for Helicobacter pylori infection

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World Journal of Gastroenterology 2012年第19期18卷 2377-2382页

作者： hyuk Soon Choi Hoon Jai Chun Sang Hoon park Bora Keum Yeon Seok Seo Yong Sik Kim Yoon-Tae Jeen Soon Ho Um Hong Sik Lee chang Duck Kim Ho Sang Ryu Division of Gastroenterology and Hepatology Department of Internal MedicineInstitute of Digestive Disease and NutritionKorea University College of MedicineSeoul 136-705South Korea

AIM:To compare the effectiveness of sequential therapy for Helicobacter pylori(***) infection with that of triple therapy of varying ***:The 460 patients enrolled in this study had ***-associated gastritis or a gastric or duodenal *** screening,***-infected patients were randomly assigned to receive either conventional triple therapy for 7,10 or 14 d,or a new 10-d sequential *** of the 4 treatment groups included 115 *** outcomes of eradication therapy were assessed 4 wk after treatment by the urea breath test and ***:The overall eradication rate was 81.0%,and eradication rates were 75.7% for 7-d conventional triple therapy,81.9% for 10-d conventional triple therapy,84.4% for 14-d conventional triple therapy,and 82.0% for 10-d sequential *** intention-to-treat analysis nor per protocol analysis showed significant differences in eradication rates using sequential therapy or the standard triple therapy(P = 0.416 and P = 0.405,respectively).CONCLUSION:There are no significant differences between 10-d sequential eradication therapy for *** and any duration of standard triple treatment in Korean patients.

关键词：疗法三联感染幽门螺旋杆菌幽门螺杆菌十二指肠协议分析治疗

Impact of tumor location on clinical outcomes of gastric endoscopic submucosal dissection

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World Journal of Gastroenterology 2014年第26期20卷 8631-8637页

作者： Ji Young Yoon Choong Nam Shim Sook Hee Chung Wan park Hyunsoo Chung hyuk Lee Sung Kwan Shin Sang Kil Lee Yong chan Lee Jun Chul park Department of Internal Medicine Institute of GastroenterologyYonsei University College of Medicine

AIM:To determine whether there is a correlation between the location of the lesion and endoscopic submucosal dissection(ESD)***:From January 2008 to December 2010,ESD of 1443 gastric tumors was *** bloc resection rate,complete resection rate,procedure time and complication rate were analyzed according to the tumor ***:The rates of en bloc resection and complete resection were 91%(1318/1443)and 89%(1287/1443),*** post-ESD bleeding rate was 4.3%,and perforation rate was 2.7%.Tumors located in the upper third of the stomach were associated with a longer procedure time and significantly higher rates of incomplete resection,piecemeal resection,and perforation than tumors below the upper third of the *** wall lesions had significantly longer procedure times and higher rates of incomplete resection and piecemeal resection than lesions in other *** multivariate analysis,posterior wall lesions and upper third lesions were significantly associated with incomplete resection and perforation,*** post-ESD bleeding analysis,location was not a significant related ***:More advanced endoscopic techniques are required during ESD for lesions located in the upper third or posterior wall of the stomach to decrease complications and improve therapeutic outcomes.

关键词： Endoscopic submucosal dissection Gastric neoplasm

金属间化合物厚度对静液挤压Al/Cu蜂窝状棒材各向异性的影响（英文）

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Transactions of Nonferrous Metals Society of China 2016年第2期26卷 456-463页

作者： Tae-hyuk LEE Moon-soo SIM Sin-hyeong JOO Kyoung-tae park Ha-guk JEONG Jong-hyeon LEE Graduate School of Department of Advanced Materials Engineering Chungnam National University Rapidly Solidified Materials Research Center Chungnam National University Graduate School of Energy Science & Technology Chungnam National University Rare Metal R&D Group Korea Institute of Industrial Technology Advanced Fusion Process R&D Group Korea Institute of Industrial Technology

研究了金属间化合物厚度对蜂窝状棒材热性能和力学性能的影响。在200℃下采用重复静液挤压制备Al/Cu蜂窝状棒材。在制备过程中,Al/Cu界面生成1μm厚的金属间化合物层。经420℃退火0.5-2 h后续热处理后,可获得不同厚度的金属间化合物层,... 详细信息

研究了金属间化合物厚度对蜂窝状棒材热性能和力学性能的影响。在200℃下采用重复静液挤压制备Al/Cu蜂窝状棒材。在制备过程中,Al/Cu界面生成1μm厚的金属间化合物层。经420℃退火0.5-2 h后续热处理后,可获得不同厚度的金属间化合物层,最厚可达10.1μm。经鉴定,金属间化合物层为Al2Cu（θ）、AlCu（η2）和Al4Cu9（γ1）相。随着金属间化合物层厚度的增加,纵向和截面方向上的热导率分别减小11.9%（从（268±4.8）到（236±4.4）W/（m·K））和10.4%（从（210±3.2）到（188±2.8）W/（m·K））,Al/Cu蜂窝状棒材的抗拉强度和伸长率分别是（103±8.4）MPa和（73±6.2）%。当金属间化合物层厚度达到7.7μm时,抗拉强度增加至（131±6.5）MPa,随着金属间化合物层厚度增加至10.1μm时,抗拉强度降低至（124±3.9）MPa。随着金属间化合物层厚度增加,蜂窝状棒材的伸长率急剧下降至（29±2.5）%。

关键词：金属间化合物 Al/Cu蜂窝状棒材各向异性热导率拉伸强度静液挤压

M-IDM: A Multi-Classication Based Intrusion Detection Model in Healthcare IoT

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Computers, Materials & Continua 2021年第5期 1537-1553页

作者： Jae Dong Lee Hyo Soung Cha Shailendra Rathore Jong hyuk park Healthcare AI Team National Cancer CenterGoyang-si10408Korea Department of Computer Science and Engineering Seoul National University of Science and Technology(SeoulTech)Seoul01811Korea

In recent years,the application of a smart city in the healthcare sector via loT systems has continued to grow exponentially and various advanced network intrusions have emerged since these loT devices are being *** studies focused on security threat detection and blocking technologies that rely on testbed data obtained from a single medical IoT device or simulation using a well-known dataset,such as the NSL-KDD ***,such approaches do not reect the features that exist in real medical scenarios,leading to failure in potential threat *** address this problem,we proposed a novel intrusion classication architecture known as a Multi-class Classication based Intrusion Detection Model(M-IDM),which typically relies on data collected by real devices and the use of convolutional neural networks(i.e.,it exhibits better performance compared with conventional machine learning algorithms,such as naïve Bayes,support vector machine(SVM)).Unlike existing studies,the proposed architecture employs the actual healthcare IoT environment of National Cancer Center in South Korea and actual network data from real medical devices,such as a patient’s monitors(i.e.,electrocardiogram and thermometers).The proposed architecture classies the data into multiple classes:Critical,informal,major,and minor,for intrusion ***,we experimentally evaluated and compared its performance with those of other conventional machine learning algorithms,including naïve Bayes,SVM,and logistic regression,using neural networks.

关键词： Smart city healthcare IoT neural network intrusion classication machine learning

Anaplastic Hemangiopericytoma Presenting as an intraparenchymal mass—Case report

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Anaplastic Hemangiopericytoma Presenting as an intraparenchy...